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  1. Article ; Online: Lymphocytic choriomeningitis virus meningoencephalitis in a renal transplant recipient following exposure to mice.

    Tanveer, Farah / Younas, Mariam / Fishbain, Joel

    Transplant infectious disease : an official journal of the Transplantation Society

    2018  Volume 20, Issue 6, Page(s) e13013

    Abstract: Solid organ transplant recipients (SOTR) are at increased risk for a wide variety of typical and atypical infections as a consequence of impaired cell mediated and humoral immunity. We report a case of meningoencephalitis in a renal transplant recipient ... ...

    Abstract Solid organ transplant recipients (SOTR) are at increased risk for a wide variety of typical and atypical infections as a consequence of impaired cell mediated and humoral immunity. We report a case of meningoencephalitis in a renal transplant recipient caused by lymphocytic choriomeningitis virus (LCMV) acquired by exposure to mice excreta. The clinical course was complicated by the development of hydrocephalus, requiring a ventriculoperitoneal shunt. To our knowledge, this is the first reported case of LCMV infection in a SOTR that was not organ donor derived.
    MeSH term(s) Adult ; Animals ; Feces/virology ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Kidney Failure, Chronic/surgery ; Kidney Transplantation/adverse effects ; Lymphocytic Choriomeningitis/therapy ; Lymphocytic Choriomeningitis/transmission ; Lymphocytic Choriomeningitis/virology ; Lymphocytic choriomeningitis virus/isolation & purification ; Male ; Meningoencephalitis/therapy ; Meningoencephalitis/transmission ; Meningoencephalitis/virology ; Mice/virology ; Physical Therapy Modalities ; Treatment Outcome
    Chemical Substances Immunoglobulins, Intravenous
    Language English
    Publishing date 2018-11-05
    Publishing country Denmark
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1476094-0
    ISSN 1399-3062 ; 1398-2273
    ISSN (online) 1399-3062
    ISSN 1398-2273
    DOI 10.1111/tid.13013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Epiploic Appendagitis: The Uncommon Intestinal Imitator.

    Garg, Rajat / Ma, Danny / Fishbain, Joel T

    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

    2017  Volume 16, Issue 1, Page(s) A36

    MeSH term(s) Colon/pathology ; Humans ; Male ; Peritonitis/diagnosis ; Peritonitis/pathology ; Radiography, Abdominal ; Tomography, X-Ray Computed ; Young Adult
    Language English
    Publishing date 2017-05-26
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2119789-1
    ISSN 1542-7714 ; 1542-3565
    ISSN (online) 1542-7714
    ISSN 1542-3565
    DOI 10.1016/j.cgh.2017.05.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Lack of effect of antibiotics on biopsy culture results in vertebral osteomyelitis.

    Saravolatz, Louis D / Labalo, Vladimir / Fishbain, Joel / Szpunar, Susan / Johnson, Leonard B

    Diagnostic microbiology and infectious disease

    2018  Volume 91, Issue 3, Page(s) 273–274

    Abstract: We report a retrospective study of 173 patients with vertebral osteomyelitis evaluating the effect of antibiotics administered prior to percutaneous and open biopsy cultures. Antibiotics given prior to these biopsies did not have a significant effect on ... ...

    Abstract We report a retrospective study of 173 patients with vertebral osteomyelitis evaluating the effect of antibiotics administered prior to percutaneous and open biopsy cultures. Antibiotics given prior to these biopsies did not have a significant effect on the yield of cultures.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/pharmacology ; Bacteria/drug effects ; Bacteria/isolation & purification ; Biopsy ; Female ; Humans ; Male ; Middle Aged ; Osteomyelitis/microbiology ; Retrospective Studies ; Spondylitis/microbiology ; Young Adult
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2018-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2018.02.017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Treatment of Acinetobacter infections.

    Fishbain, Joel / Peleg, Anton Y

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2010  Volume 51, Issue 1, Page(s) 79–84

    Abstract: Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose resistance patterns result in significant challenges for the clinician. Despite the prevalence and interest in A. baumannii infections, there is relatively limited well- ... ...

    Abstract Acinetobacter baumannii remains an important and difficult-to-treat pathogen whose resistance patterns result in significant challenges for the clinician. Despite the prevalence and interest in A. baumannii infections, there is relatively limited well-controlled scientific data to help the clinician select optimal empirical and subsequent targeted therapy for a variety of infections. We will review the currently available antimicrobial agents and discuss the clinical data supporting the use of the various agents.
    MeSH term(s) Acinetobacter Infections/drug therapy ; Acinetobacter baumannii/drug effects ; Anti-Infective Agents/therapeutic use ; Drug Resistance, Bacterial ; Drug Therapy, Combination ; Humans
    Chemical Substances Anti-Infective Agents
    Language English
    Publishing date 2010-07-01
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1086/653120
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The role of intravenous catheters in cardiovascular implantable electronic device infections: identifying potential targets for prevention.

    Othman, Hussein / Fishbain, Joel T / Khatib, Riad

    American journal of infection control

    2013  Volume 41, Issue 4, Page(s) 376–377

    Abstract: Infections related to cardiac implantable electronic devices (CIEDs) are increasing in prevalence and carry substantial morbidity and mortality. Complications involving peripheral intravenous catheters resulting in CIED infections have not yet been ... ...

    Abstract Infections related to cardiac implantable electronic devices (CIEDs) are increasing in prevalence and carry substantial morbidity and mortality. Complications involving peripheral intravenous catheters resulting in CIED infections have not yet been investigated and may pose an important risk factor. We report 5 cases of CIED infection related to documented complications of peripheral vascular devices.
    MeSH term(s) Catheters/microbiology ; Catheters/utilization ; Female ; Humans ; Male ; Middle Aged ; Pacemaker, Artificial/adverse effects ; Prosthesis-Related Infections/epidemiology ; Prosthesis-Related Infections/etiology ; Retrospective Studies
    Language English
    Publishing date 2013-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2012.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Invasive Bordetella holmesii infections.

    Fishbain, Joel T / Riederer, Kathleen / Sawaf, Hadi / Mody, Rupal

    Infectious diseases (London, England)

    2015  Volume 47, Issue 2, Page(s) 65–68

    Abstract: Bordetella holmesii is a rare cause of invasive human disease. The fastidious and unusual nature of this organism makes routine isolation and identification challenging. We report two cases of B. holmesii bacteremia that were rapidly identified by matrix- ...

    Abstract Bordetella holmesii is a rare cause of invasive human disease. The fastidious and unusual nature of this organism makes routine isolation and identification challenging. We report two cases of B. holmesii bacteremia that were rapidly identified by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS) when standard techniques failed to provide speciation. There are no current standards for susceptibility testing or treatment recommendations. The rare occurrence and challenges in identifying this pathogen led us to perform a comprehensive review of the epidemiology, clinical presentations, and treatment options for this potentially invasive pathogen.
    MeSH term(s) Aged ; Anti-Bacterial Agents/therapeutic use ; Bordetella/isolation & purification ; Bordetella Infections/diagnosis ; Bordetella Infections/drug therapy ; Bordetella Infections/microbiology ; Ciprofloxacin/therapeutic use ; Female ; Humans ; Male ; Young Adult
    Chemical Substances Anti-Bacterial Agents ; Ciprofloxacin (5E8K9I0O4U)
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2839775-7
    ISSN 2374-4243 ; 2374-4235
    ISSN (online) 2374-4243
    ISSN 2374-4235
    DOI 10.3109/00365548.2014.968609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinical value of chest computerized tomography scans in patients admitted with pneumonia.

    Garg, Deepak / Johnson, Leonard B / Szpunar, Susan / Fishbain, Joel T

    Journal of hospital medicine

    2014  Volume 9, Issue 7, Page(s) 447–450

    Abstract: Patients admitted with pneumonia often receive a chest computed tomography (CT) scan for a variety of reasons. We conducted this study to evaluate our overall utilization and the clinical impact of CT scans in patients admitted to our institution with ... ...

    Abstract Patients admitted with pneumonia often receive a chest computed tomography (CT) scan for a variety of reasons. We conducted this study to evaluate our overall utilization and the clinical impact of CT scans in patients admitted to our institution with pneumonia. Patients admitted to our facility from January 2008 through November 2011 with a confirmed diagnosis of pneumonia were eligible for evaluation. Information related to patient demographics, performance of a CT scan, pneumonia-related procedures, severity of illness, and outcomes was collected. One hundred ninety-five patients met inclusion criteria. Sixty-nine patients had CT scans performed. CT scans were performed more often in younger patients (58.1 ± 19.0 vs 66.8 ± 18.6, P = 0.002), individuals with lower CURB 65 (Confusion, Urea, Respiratory rate, Blood pressure, Age > 65) scores (1.7 ± 1.4 vs 2.2 ± 1.4, P = 0.037), and those with no infiltrates or consolidation on plain radiographs (26.9% vs 7.1%, P < 0.0001). Patients who had a procedure performed had longer average length of stays (15.3 ± 11.9 vs 6.8 ± 4.1 days, P = 0.016). Pneumonia-related procedures were more likely performed in patients who had a CT scan. Specific guidelines and objective rules need to be developed to prospectively guide the use of advanced imaging techniques in pneumonia patients.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Patient Admission/trends ; Pneumonia/diagnostic imaging ; Pneumonia/therapy ; Radiography, Thoracic/methods ; Radiography, Thoracic/standards ; Retrospective Studies ; Tomography, X-Ray Computed/methods ; Tomography, X-Ray Computed/standards
    Language English
    Publishing date 2014-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.2190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: MALDI-TOF identification of Gram-negative bacteria directly from blood culture bottles containing charcoal: Sepsityper® kits versus centrifugation-filtration method.

    Riederer, Kathleen / Cruz, Kristian / Shemes, Stephen / Szpunar, Susan / Fishbain, Joel T

    Diagnostic microbiology and infectious disease

    2015  Volume 82, Issue 2, Page(s) 105–108

    Abstract: Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry has dramatically altered the way microbiology laboratories identify clinical isolates. Direct blood culture (BC) detection may be hampered, however, by the presence ... ...

    Abstract Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry has dramatically altered the way microbiology laboratories identify clinical isolates. Direct blood culture (BC) detection may be hampered, however, by the presence of charcoal in BC bottles currently in clinical use. This study evaluates an in-house process for extraction and MALDI-TOF identification of Gram-negative bacteria directly from BC bottles containing charcoal. Three hundred BC aliquots were extracted by a centrifugation-filtration method developed in our research laboratory with the first 96 samples processed in parallel using Sepsityper® kits. Controls were colonies from solid media with standard phenotypic and MALDI-TOF identification. The identification of Gram-negative bacteria was successful more often via the in-house method compared to Sepsityper® kits (94.7% versus 78.1%, P≤0.0001). Our in-house centrifugation-filtration method was further validated for isolation and identification of Gram-negative bacteria (95%; n=300) directly from BC bottles containing charcoal.
    MeSH term(s) Bacteremia/diagnosis ; Bacteremia/microbiology ; Blood/microbiology ; Centrifugation/methods ; Charcoal/isolation & purification ; Filtration/methods ; Gram-Negative Bacteria/chemistry ; Gram-Negative Bacteria/classification ; Gram-Negative Bacteria/isolation & purification ; Humans ; Sensitivity and Specificity ; Specimen Handling/methods ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods
    Chemical Substances Charcoal (16291-96-6)
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Comparative Study ; Evaluation Studies ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604920-5
    ISSN 1879-0070 ; 0732-8893
    ISSN (online) 1879-0070
    ISSN 0732-8893
    DOI 10.1016/j.diagmicrobio.2015.03.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Aerosolized biologic toxins as agents of warfare and terrorism.

    Zapor, Michael / Fishbain, Joel T

    Respiratory care clinics of North America

    2004  Volume 10, Issue 1, Page(s) 111–122

    Abstract: Incomplete participation in the 1972 Biological Weapons Convention treaty and noncompliance by several signatory nations makes the malicious use of aerosolized biologic toxins a continuing threat. Unfortunately,prompt diagnosis of toxin exposure may be ... ...

    Abstract Incomplete participation in the 1972 Biological Weapons Convention treaty and noncompliance by several signatory nations makes the malicious use of aerosolized biologic toxins a continuing threat. Unfortunately,prompt diagnosis of toxin exposure may be confounded by a paucity of pathognomonic features and limited diagnostics, but the scenario of patients presenting en masse with a similar pulmonary syndrome should alert the clinician to the possibility of aerosolized toxin exposure. As knowledge of these agents increases, so too should the capabilities for detection,protection, diagnosis, and therapy. This improved understanding, coupled with ongoing public education and awareness and with detailed proactive planning will provide the framework for a prepared community.
    MeSH term(s) Aerosols ; Bioterrorism ; Disaster Planning ; Enterotoxins ; Humans ; Mycotoxins ; Respiratory Tract Infections/microbiology ; Respiratory Tract Infections/prevention & control ; Ricin ; Staphylococcus aureus ; Trichothecenes ; United States
    Chemical Substances Aerosols ; Enterotoxins ; Mycotoxins ; Trichothecenes ; Ricin (9009-86-3)
    Language English
    Publishing date 2004-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1384525-1
    ISSN 1078-5337
    ISSN 1078-5337
    DOI 10.1016/S1078-5337(03)00054-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Use of portable electronic devices in a hospital setting and their potential for bacterial colonization.

    Khan, Amber / Rao, Amitha / Reyes-Sacin, Carlos / Hayakawa, Kayoko / Szpunar, Susan / Riederer, Kathleen / Kaye, Keith / Fishbain, Joel T / Levine, Diane

    American journal of infection control

    2015  Volume 43, Issue 3, Page(s) 286–288

    Abstract: Portable electronic devices are increasingly being used in the hospital setting. As with other fomites, these devices represent a potential reservoir for the transmission of pathogens. We conducted a convenience sampling of devices in 2 large medical ... ...

    Abstract Portable electronic devices are increasingly being used in the hospital setting. As with other fomites, these devices represent a potential reservoir for the transmission of pathogens. We conducted a convenience sampling of devices in 2 large medical centers to identify bacterial colonization rates and potential risk factors.
    MeSH term(s) Bacteria/isolation & purification ; Environmental Microbiology ; Equipment and Supplies ; Fomites ; Hospitals ; Humans ; Mobile Applications
    Language English
    Publishing date 2015-03-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2014.11.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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