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  1. Article ; Online: Subcallosal Occlusion Following Anterior Communicating Aneurysm Treatment.

    Holay, Quentin / Piotin, Michel / Escalard, Simon

    Neurology

    2022  Volume 99, Issue 12, Page(s) 522–523

    MeSH term(s) Amnesia, Anterograde ; Aneurysm, Ruptured/complications ; Aneurysm, Ruptured/diagnostic imaging ; Cerebral Angiography ; Humans ; Imaging, Three-Dimensional ; Intracranial Aneurysm/complications ; Intracranial Aneurysm/diagnostic imaging ; Ischemic Stroke/diagnostic imaging ; Korsakoff Syndrome/diagnostic imaging ; Magnetic Resonance Imaging ; Male ; Middle Aged
    Language English
    Publishing date 2022-08-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000201067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Complication of Ear Impression: Foreign Body in the Eustachian Tube Eroding the Carotid Canal.

    Shenouda, Kerolos / Poillon, Guillaume / Gargula, Stéphane / Hervé, Camille / Escalard, Simon / Ayache, Denis / Daval, Mary

    The Laryngoscope

    2023  Volume 133, Issue 12, Page(s) 3358–3360

    Abstract: The realization of customized earing plugs and earmolds for hearing aids requires an impression of the external auditory canal to obtain a siliconized mold. Silicone used for ear impressions is known to be safe and inert but deposition of silicone in the ...

    Abstract The realization of customized earing plugs and earmolds for hearing aids requires an impression of the external auditory canal to obtain a siliconized mold. Silicone used for ear impressions is known to be safe and inert but deposition of silicone in the middle ear can middle and inner ear damages. We present a case of accidental injection of silicone in the middle ear and the Eustachian tube resulting in an erosion of the carotid canal. Laryngoscope, 133:3358-3360, 2023.
    MeSH term(s) Humans ; Eustachian Tube/surgery ; Ear, Middle ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/etiology ; Foreign Bodies/surgery ; Silicones/adverse effects ; Ear, Inner ; Ear Canal
    Chemical Substances Silicones
    Language English
    Publishing date 2023-08-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.30932
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  3. Article ; Online: Left temporal hemorrhage caused by cerebral venous reflux of a brachio-brachial hemodialysis fistula.

    Haruma, Jun / Escalard, Simon / Smajda, Stanislas / Piotin, Michel

    Neuroradiology

    2020  Volume 62, Issue 10, Page(s) 1341–1344

    Abstract: Central vein disease (CVD) is a well-known complication of central venous cannulations, indwelling dialysis catheters, and arteriovenous grafts. Brachiocephalic vein (BCV) stenosis or thrombotic occlusion can occur in dialysis patients, and the presence ... ...

    Abstract Central vein disease (CVD) is a well-known complication of central venous cannulations, indwelling dialysis catheters, and arteriovenous grafts. Brachiocephalic vein (BCV) stenosis or thrombotic occlusion can occur in dialysis patients, and the presence of an ipsilateral arteriovenous fistula can cause cerebral venous hypertension due to retrograde flow in the ipsilateral jugular vein. A 53-year-old man receiving hemodialysis (left brachiocephalic hemodialysis fistula) presented with impaired consciousness and seizures related to status epilepticus due to left temporal multifocal hemorrhages. Brain computed tomography and angiogram showed left cortical vein congestion without intracranial arteriovenous shunt. Complementary left brachial angiogram showed a left BCV stenosis and jugular and cerebral high-flow venous reflux with cortical venous reflux from the hemodialysis fistula. The left arm shunt resulted in severe cerebral venous hypertension due to ipsilateral stenosis of the BCV. BCV angioplasty immediately resolved the cerebral reflux. Patients with hemodialysis fistulas are at a higher risk of developing these intracerebral hemorrhage complications.
    MeSH term(s) Angiography, Digital Subtraction ; Arteriovenous Shunt, Surgical/adverse effects ; Brachiocephalic Veins ; Cerebral Angiography ; Cerebral Hemorrhage/diagnostic imaging ; Cerebral Hemorrhage/etiology ; Cerebral Hemorrhage/therapy ; Computed Tomography Angiography ; Contrast Media ; Glasgow Coma Scale ; Humans ; Kidney Failure, Chronic/therapy ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Renal Dialysis
    Chemical Substances Contrast Media
    Language English
    Publishing date 2020-05-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123305-1
    ISSN 1432-1920 ; 0028-3940
    ISSN (online) 1432-1920
    ISSN 0028-3940
    DOI 10.1007/s00234-020-02457-1
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  4. Article ; Conference proceedings: The GECKO 60 Active Wire for Neurovascular Interventions

    Piotin, Michel / Escalard, Simon / Smajda, Stanislas / Redjem, Hocine / Boisseau, William / Al Raaisi, Amira / Désilles, Jean-Philippe / Mazighi, Mikael / Delvoye, François

    The Arab Journal of Interventional Radiology

    2023  Volume 07, Issue S 01

    Event/congress PAIRS 2023 Annual Congress, Grand Hyatt Hotel, Dubai, UAE, 2023-02-11
    Language English
    Publishing date 2023-02-01
    Publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2542-7083 ; 2542-7075
    ISSN (online) 2542-7083
    ISSN 2542-7075
    DOI 10.1055/s-0043-1763461
    Database Thieme publisher's database

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  5. Article ; Online: Mechanical thrombectomy in basilar artery occlusions: impact of first-line strategy as a function of the occlusion level.

    Tournier, Louis / Cortese, Jonathan / Consoli, Arturo / Spelle, Laurent / Marnat, Gaultier / Sarov, Mariana / Zhu, Francois / Soize, Sebastien / Burel, Julien / Forestier, Géraud / Escalard, Simon / Pop, Raoul / Bonnet, Baptiste / Alias, Quentin / Ognard, Julien / Naggara, Olivier / Kyheng, Maeva / Lapergue, Bertrand / Caroff, Jildaz

    Journal of neurointerventional surgery

    2024  

    Abstract: Background: Retrospective studies suggest the superiority of first-line contact aspiration (CA) thrombectomy over stent-retriever (SR) in basilar artery occlusions (BAO). We aimed to investigate the impact of first-line mechanical thrombectomy per the ... ...

    Abstract Background: Retrospective studies suggest the superiority of first-line contact aspiration (CA) thrombectomy over stent-retriever (SR) in basilar artery occlusions (BAO). We aimed to investigate the impact of first-line mechanical thrombectomy per the occlusion level, considering differences in stroke etiology prevalence between proximal and distal BAO.
    Methods: A retrospective, multicentric analysis of the Endovascular Treatment in Ischemic Stroke Registry (ETIS) included consecutive BAO patients treated from January 2016 to May 2022. Patients were categorized into SR (±aspiration) and CA alone groups. Occlusion levels were determined through digital subtraction angiography. Favorable clinical outcome was defined as 90-day modified Rankin Scale (mRS) 0-3.
    Results: A total of 380 patients were analyzed (251 CA alone, 129 SR±aspiration). Globally, first-line SR showed lower recanalization rates (89.1% vs 94.8%, OR=0.29, 95% CI 0.16 to 0.53; p<0.001) and worse clinical outcomes (mRS 0-3: 46.0% vs 52.2%, OR=0.62, 95% CI 0.44 to 0.87; p=0.006) compared with CA. In proximal occlusions, SR was significantly associated with poorer clinical outcomes (mRS 0-3: 20.9% vs 37.1%; OR=0.40, 95% CI 0.19 to 0.83; p=0.014) despite similar recanalization rates. Conversely, in distal occlusions there was no difference in clinical outcomes although recanalization rates were higher with CA (modified Thrombolysis in Cerebral Infarction score (mTICI 2b/3): 97.7% vs 91.7%; OR=0.17, 95% CI 0.05 to 0.66; p=0.01).
    Conclusions: In our BAO population, CA demonstrated better angiographic outcomes in middle and distal occlusions and better clinical outcomes in proximal occlusions. This translated into better angiographic and clinical results in the global study population. Clinical results were particularly influenced by the negative impact of SR on 90-day mRS, independently of recanalization rates in proximal BAO.
    Language English
    Publishing date 2024-03-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/jnis-2024-021491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Treated unruptured cerebral aneurysm in elderly patients: a single center study.

    Metayer, Thomas / Blanc, Raphael / Smajda, Stanislas / Desilles, Jean Philippe / Redjem, Hocine / Escalard, Simon / Mazighi, Mikael / Tayeb, Adnan Al / Robichon, Erwan / Raaisi, Amira Al / Boisseau, William / Delvoye, Francois / Piotin, Michel

    Neuro-Chirurgie

    2023  Volume 70, Issue 1, Page(s) 101522

    Abstract: Introduction: The increase in life expectancy raises the question of the treatment of unruptured intracranial aneurysms in extremely old patients (>80 years). We present results in terms of occlusion and complications in both symptomatic and ... ...

    Abstract Introduction: The increase in life expectancy raises the question of the treatment of unruptured intracranial aneurysms in extremely old patients (>80 years). We present results in terms of occlusion and complications in both symptomatic and asymptomatic aneurysm.
    Methods: All patients aged >80 years admitted to the Foundation Adolphe de Rothschild between January 1, 2005 and March, 2023 were included. Aneurysms were grouped as compressive and non-compressive. Procedural complications were grouped as symptomatic (i.e., leading to any temporary or permanent neurological deficit) and severe (defined by modified Rankin Scale (mRS) ≥3 at follow-up).
    Results: Forty-two aneurysms were treated in the study period. Coiling (with or without remodeling) was the treatment of choice in 30 patients. Eighteen patients had compressive aneurysm. Six complications occurred (14.2%), all ischemic. The majority of complications occurred in symptomatic aneurysms, in 4 patients (66.6%). One of the patients treated by flow-diverter had severe complications (mRs ≥3) with hemiplegia.
    Conclusion: In extremely specific cases, treatment of unruptured aneurysm in people older than 80 years may be considered. Compressive aneurysm is associated with a high risk of complications. Treatments can be endovascular. Further prospective studies are required to confirm this hypothesis.
    MeSH term(s) Aged ; Humans ; Intracranial Aneurysm/surgery ; Intracranial Aneurysm/complications ; Treatment Outcome ; Endovascular Procedures/methods ; Embolization, Therapeutic/methods ; Prospective Studies ; Retrospective Studies ; Stents
    Language English
    Publishing date 2023-12-14
    Publishing country France
    Document type Journal Article
    ZDB-ID 207146-0
    ISSN 1773-0619 ; 0028-3770 ; 0150-9586
    ISSN (online) 1773-0619
    ISSN 0028-3770 ; 0150-9586
    DOI 10.1016/j.neuchi.2023.101522
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Embolization of the middle meningeal artery for the prevention of chronic subdural hematoma recurrence in high-risk patients: a randomized controlled trial-the EMPROTECT study protocol.

    Shotar, Eimad / Mathon, Bertrand / Rouchaud, Aymeric / Mounayer, Charbel / Salle, Henri / Bricout, Nicolas / Lejeune, Jean-Paul / Janot, Kevin / Zemmoura, Ilyess / Naggara, Olivier / Roux, Alexandre / Goutagny, Stéphane / Guedon, Alexis / Brunel, Herve / Troude, Lucas / Dufour, Henry / Bernat, Anne-Laure / Tuilier, Titien / Bresson, Damien /
    Apra, Caroline / Fouet, Mathilde / Escalard, Simon / Chauvet, Dorian / Baptiste, Amandine / Lebbah, Said / Dechartres, Agnès / Clarençon, Frédéric

    Journal of neurointerventional surgery

    2024  

    Abstract: Background: Middle meningeal artery (MMA) embolization has been proposed as a treatment of chronic subdural hematoma (CSDH). The benefit of the procedure has yet to be demonstrated in a randomized controlled trial. We aim to assess the efficacy of MMA ... ...

    Abstract Background: Middle meningeal artery (MMA) embolization has been proposed as a treatment of chronic subdural hematoma (CSDH). The benefit of the procedure has yet to be demonstrated in a randomized controlled trial. We aim to assess the efficacy of MMA embolization in reducing the risk of CSDH recurrence 6 months after burr-hole surgery compared with standard medical treatment in patients at high risk of postoperative recurrence.
    Methods: The EMPROTECT trial is a multicenter open label randomized controlled trial (RCT) involving 12 French centers. Adult patients (≥18 years) operated for CSDH recurrence or for a first episode with a predefined recurrence risk factor are randomized 1:1 to receive either MMA embolization within 7 days of the burr-hole surgery (experimental group) or standard medical care (control group). The number of patients to be included is 342.
    Results: The primary outcome is the rate of CSDH recurrence at 6 months. Secondary outcomes include the rate of repeated surgery for a homolateral CSDH recurrence during the 6-month follow-up period, the rate of disability and dependency at 1 and 6 months, defined by a modified Rankin Scale (mRS) score ≥4, mortality at 1 and 6 months, total cumulative duration of hospital stay during the 6-month follow-up period, directly or indirectly related to the CSDH and embolization procedure-related complication rates.
    Conclusions: The EMPROTECT trial is the first RCT evaluating the benefit of MMA embolization as a surgical adjunct for the prevention of CSDH recurrence. If positive, this trial will have a significant impact on patient care.
    Trial registration number: NCT04372147.
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2514982-9
    ISSN 1759-8486 ; 1759-8478
    ISSN (online) 1759-8486
    ISSN 1759-8478
    DOI 10.1136/jnis-2023-021249
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  8. Article ; Online: Long-term outcome of endovascular treatment for indirect carotid-cavernous fistulas.

    Baharvahdat, Humain / Qoorchi Moheb Seraj, Farid / Al-Raaisi, Amira / Blanc, Raphael / Najafi, Sajjad / Mirbolouk, Mohammad Hossein / Redjem, Hocine / Ebrahimnia, Feizollah / Escalard, Simon / Zabihyan, Samira / Desilles, Jean-Philipe / Mowla, Ashkan / Boisseau, Willian / Mazighi, Mikael / Smajda, Stanislas / Piotin, Michel

    Neurosurgical focus

    2023  Volume 56, Issue 3, Page(s) E5

    Abstract: Objective: Endovascular treatment (EVT) is the primary approach used to treat indirect carotid-cavernous fistulas (CCFs). In this study, the authors evaluated the immediate and long-term efficacy and safety of different endovascular techniques for ... ...

    Abstract Objective: Endovascular treatment (EVT) is the primary approach used to treat indirect carotid-cavernous fistulas (CCFs). In this study, the authors evaluated the immediate and long-term efficacy and safety of different endovascular techniques for indirect CCFs.
    Methods: The databases of two endovascular centers were retrospectively reviewed to collect the patients with indirect CCFs treated using endovascular techniques between 2013 and 2023. Demographics, clinical presentation, CCF features, EVT characteristics, and clinical and radiological outcomes were evaluated and analyzed. The analysis was performed to compare the clinical and radiological data between different endovascular approaches and different embolic materials.
    Results: Ninety-eight patients were included in the study. EVT was successful in 95 patients (96.9%). Immediate complete obliteration of the CCF was achieved in 93.9% of patients, with 98% undergoing embolization with liquid embolic agents (LEAs) and 95.6% undergoing coiling alone. Complete CCF obliteration was higher in the transvenous than in the transarterial approach (94.3% vs 75%, p = 0.010). At ≥ 6 months follow-up, complete CCF obliteration was achieved in all patients (100%). The rate of procedure-related complications was higher following LEAs than with coiling alone (32.0% vs 15.6%). New cranial nerve (CN) palsy was diagnosed in 26.0% and 2.2% after embolization with LEAs and coiling alone, respectively (p = 0.001), with complete CN palsy recovery in 78.6%. Procedure-related intracranial hemorrhage occurred in 3 patients (3.1%). Two patients experienced an ischemic stroke following Onyx migration into the internal carotid artery. Ocular symptoms improved in 93% (83/89) of the patients who were followed.
    Conclusions: In this study, complete obliteration of an indirect CCF was achieved in more than 90% of patients. Despite the occurrence of some new postprocedural ocular CN palsy, ocular symptoms improved in most patients in long-term follow-up. The transvenous approach was the most effective method for treating the indirect CCF. Coiling was safer than LEAs for the embolization of the indirect CCF.
    MeSH term(s) Humans ; Carotid-Cavernous Sinus Fistula/diagnostic imaging ; Carotid-Cavernous Sinus Fistula/surgery ; Treatment Outcome ; Retrospective Studies ; Embolization, Therapeutic/methods ; Endovascular Procedures/methods ; Paralysis/complications ; Paralysis/therapy
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2026589-X
    ISSN 1092-0684 ; 1092-0684
    ISSN (online) 1092-0684
    ISSN 1092-0684
    DOI 10.3171/2023.12.FOCUS23795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prediction of Early Intracranial Hypertension After Severe Traumatic Brain Injury: A Prospective Study.

    Martin, Mathieu / Lobo, David / Bitot, Valérie / Couffin, Séverine / Escalard, Simon / Mounier, Roman / Cook, Fabrice

    World neurosurgery

    2019  Volume 127, Page(s) e1242–e1248

    Abstract: Objective: This study aimed to assess the reliability of clinical features, noninvasive transcranial Doppler-related pulsatility index (PI) calculation, and optic nerve sheath diameter (ONSD) measured by ultrasound (US) and initial computed tomography ( ... ...

    Abstract Objective: This study aimed to assess the reliability of clinical features, noninvasive transcranial Doppler-related pulsatility index (PI) calculation, and optic nerve sheath diameter (ONSD) measured by ultrasound (US) and initial computed tomography (CT) scan (Marshall CT scan classification) in predicting the occurrence of early (<24 hours) high intracranial pressure (EHICP) (>20 mm Hg) after severe traumatic brain injury (TBI).
    Methods: We conducted an observational prospective study in a level 1 trauma center. Patients were measured simultaneously for PI and US ONSD in the triage zone. Patients were categorized into 2 groups: those who had EHICP after TBI (EHICP+) and those who did not (EHICP-).
    Results: Fifty-four patients were included; 32 were categorized as EHICP+ and 22 as EHICP-. PI >1.4 did not correlate with EHICP+ patients (69% vs. 46%, P = 0.09). US ONSD measurement was higher in the EHICP+ group (6.25; range, 6-6.95 vs. 5.7; range, 5.2-6.4; P = 0.005). The area under the receiver operating characteristic curve for US ONSD as a predictor of developing EHICP was 0.73 (95% confidence interval [CI], 0.59-0.86). CT ONSD measurement was higher in the EHICP+ group (6.71; range, 6.35-7.87 vs. 6.25; range, 5.8-6.93; P = 0.04). The area under the receiver operating characteristic curve for CT ONSD measurement as a predictor for EHICP+ was 0.67 (95% CI, 0.53-0.81). The diffuse injury III and IV categories in the Marshall CT scan classification were associated with the occurrence of EHICP (P = 0.004).
    Conclusions: None of the clinical features or noninvasive tools assessed in this study enabled clinicians to strictly ascertain EHICP. Further studies are needed to establish their potential role before intracranial pressure probe insertion.
    MeSH term(s) Adult ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/diagnostic imaging ; Female ; Humans ; Intracranial Hypertension/diagnostic imaging ; Intracranial Hypertension/etiology ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; Severity of Illness Index ; Young Adult
    Language English
    Publishing date 2019-04-19
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2019.04.121
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  10. Article ; Online: Early Brain Imaging Shows Increased Severity of Acute Ischemic Strokes With Large Vessel Occlusion in COVID-19 Patients.

    Escalard, Simon / Chalumeau, Vanessa / Escalard, Clément / Redjem, Hocine / Delvoye, François / Hébert, Solène / Smajda, Stanislas / Ciccio, Gabriele / Desilles, Jean-Philippe / Mazighi, Mikael / Blanc, Raphael / Maïer, Benjamin / Piotin, Michel

    Stroke

    2020  Volume 51, Issue 11, Page(s) 3366–3370

    Abstract: Background and purpose: Reports are emerging regarding the association of acute ischemic strokes with large vessel occlusion and coronavirus disease 2019 (COVID-19). While a higher severity of these patients could be expected from the addition of both ... ...

    Abstract Background and purpose: Reports are emerging regarding the association of acute ischemic strokes with large vessel occlusion and coronavirus disease 2019 (COVID-19). While a higher severity of these patients could be expected from the addition of both respiratory and neurological injury, COVID-19 patients with strokes can present with mild or none respiratory symptoms. We aimed to compare anterior circulation large vessel occlusion strokes severity between patients with and without COVID-19.
    Methods: We performed a comparative cohort study between patients with COVID-19 who had anterior circulation large vessel occlusion and early brain imaging within 3 hours from onset, in our institution during the 6 first weeks of the COVID-19 outbreak and a control group admitted during the same calendar period in 2019.
    Results: Twelve COVID-19 patients with anterior circulation large vessel occlusion and early brain imaging were included during the study period and compared with 34 control patients with anterior circulation large vessel occlusion and early brain imaging in 2019. Patients in the COVID-19 group were younger (
    Conclusions: Early brain imaging showed higher severity large vessel occlusion strokes in patients with COVID-19. Given the massive number of infected patients, concerns should be raised about the coming neurovascular impact of the pandemic worldwide.
    MeSH term(s) Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Case-Control Studies ; Cerebral Angiography ; Computed Tomography Angiography ; Coronavirus Infections/complications ; Diffusion Magnetic Resonance Imaging ; Female ; Hospital Mortality ; Humans ; Infarction, Anterior Cerebral Artery/complications ; Infarction, Anterior Cerebral Artery/diagnostic imaging ; Infarction, Anterior Cerebral Artery/physiopathology ; Infarction, Anterior Cerebral Artery/therapy ; Infarction, Middle Cerebral Artery/complications ; Infarction, Middle Cerebral Artery/diagnostic imaging ; Infarction, Middle Cerebral Artery/physiopathology ; Infarction, Middle Cerebral Artery/therapy ; Infarction, Posterior Cerebral Artery/complications ; Infarction, Posterior Cerebral Artery/diagnostic imaging ; Infarction, Posterior Cerebral Artery/physiopathology ; Infarction, Posterior Cerebral Artery/therapy ; Magnetic Resonance Angiography ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; SARS-CoV-2 ; Severity of Illness Index ; Stroke/complications ; Stroke/diagnostic imaging ; Stroke/physiopathology ; Stroke/therapy ; Thrombectomy ; Thrombolytic Therapy
    Keywords covid19
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.120.031011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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