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  1. Article ; Online: Miliaria Scarlatinosa, A Peculiar and Rare Form of Scarlet Fever - A Case Report.

    Stojković-Filipović, Jelena / Bosić, Martina / Nikolić, Miloš / Lalošević, Jovan

    Acta dermatovenerologica Croatica : ADC

    2023  Volume 29, Issue 4, Page(s) 228–231

    Abstract: Scarlet fever typically presents with distinctive erythematous papular rash following pharyngitis. Atypical forms may develop, making the diagnosis difficult. We present the case of a girl with fever, and unusual vesicular skin eruption (miliaria ... ...

    Abstract Scarlet fever typically presents with distinctive erythematous papular rash following pharyngitis. Atypical forms may develop, making the diagnosis difficult. We present the case of a girl with fever, and unusual vesicular skin eruption (miliaria scarlatinosa) preceded by a skin infection, without mucosal changes. Leukocyte count, C-reactive protein, and antistreptolysin O-titer were elevated. Bacteriological swabs of the skin injury revealed Streptococcus pyogenes. Histopathology was compatible with scarlet fever exanthema. Intramuscular penicillin and topical wound care induced complete remission. It is of great importance to be aware of uncommon clinical presentations of scarlet fever in order to establish a timely diagnosis and prevent potential complications.
    MeSH term(s) Female ; Humans ; Scarlet Fever/complications ; Scarlet Fever/diagnosis ; Streptococcus pyogenes ; Pharyngitis/complications ; Penicillins ; Miliaria/complications
    Chemical Substances Penicillins
    Language English
    Publishing date 2023-03-10
    Publishing country Croatia
    Document type Case Reports
    ZDB-ID 1180727-1
    ISSN 1847-6538 ; 1330-027X
    ISSN (online) 1847-6538
    ISSN 1330-027X
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  2. Article ; Online: Treatment of COVID 19-Repurposing drugs commonly used in dermatology.

    Stojkovic-Filipovic, Jelena / Bosic, Martina

    Dermatologic therapy

    2020  Volume 33, Issue 5, Page(s) e13829

    Abstract: For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of corona virus disease 19 ( ... ...

    Abstract For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of corona virus disease 19 (COVID-19) highlighted the urgent need for effective treatment, and initiated rapid search for therapies, able to counter the most severe disease effects. Many aspects of COVID-19 pathogenesis are unknown, but complex interplay of direct viral damage and immune response dysregulation is underline. Intensive research is undergoing for therapeutic targets of virus and high-efficiency and low toxicity targeted drugs. There is no available specific antiviral treatment of this disease, therefore repurposing of drugs already available for the treatment of other viral and autoimmune diseases has been a part of research efforts. Well known anti-inflammatory properties of chloroquine and hydroxychloroquine, agents widely used in dermatology, made them potential candidates for the treatment of COVID-19. We review pathogenesis and clinical characteristic of COVID-19, as well as treatment options that have been under evaluation in past several months. In addition, we focus more on chloroquine and hydroxychloroquine, their pharmacological properties, clinical utility, and current recommendations for their use in COVID-19.
    MeSH term(s) Antiviral Agents/therapeutic use ; COVID-19/complications ; Chloroquine/adverse effects ; Chloroquine/therapeutic use ; Dermatology ; Drug Repositioning ; Humans ; Hydroxychloroquine/adverse effects ; Hydroxychloroquine/therapeutic use ; SARS-CoV-2 ; COVID-19 Drug Treatment
    Chemical Substances Antiviral Agents ; Hydroxychloroquine (4QWG6N8QKH) ; Chloroquine (886U3H6UFF)
    Keywords covid19
    Language English
    Publishing date 2020-07-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13829
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  3. Article ; Online: Treatment of COVID 19—Repurposing drugs commonly used in dermatology

    Stojkovic‐Filipovic, Jelena / Bosic, Martina

    Dermatologic Therapy

    2020  Volume 33, Issue 5

    Keywords Dermatology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13829
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  4. Article: Treatment of Covid19 - Repurposing drugs commonly used in dermatology

    Stojkovic-Filipovic, Jelena / Bosic, Martina

    Dermatol. ther

    Abstract: For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of Corona Virus disease 19 ( ... ...

    Abstract For the last two decades, the outbreaks of diseases caused by coronaviruses and intermittent worldwide public health emergences have reminded us that they still represent a severe threat to global health. The recent outbreak of Corona Virus disease 19 (COVID-19) highlighted the urgent need for effective treatment, and initiated rapid search for therapies, able to counter the most severe disease effects. Many aspects of COVID-19 pathogenesis are unknown, but complex interplay of direct viral damage and immune response dysregulation is underline. Intensive research is undergoing for therapeutic targets of virus and high-efficiency and low toxicity targeted drugs. There is no available specific antiviral treatment of this disease, therefore repurposing of drugs already available for the treatment of other viral and autoimmune diseases has been a part of research efforts. Well known anti-inflammatory properties of Chloroquine and Hydroxychloroquine, agents widely used in dermatology, made them potential candidates for the treatment of COVID-19. We review pathogenesis and clinical characteristic of COVID-19, as well as treatment options that have been under evaluation in past several months. In addition, we focus more on Chloroquine and Hydroxychloroquine, their pharmacological properties, clinical utility, and current recommendations for their use in COVID-19. This article is protected by copyright. All rights reserved.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #598793
    Database COVID19

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  5. Article: Pemphigus herpetiformis - a case report of a rare form of pemphigus and review of the literature.

    Stojković-Filipović, Jelena / Lekić, Branislav / Milčić, Danijela / Milinković, Mirjana V

    Vojnosanitetski pregled

    2016  Volume 73, Issue 10, Page(s) 967–972

    Abstract: Introduction: Pemphigus herpetiformis is the rare variant of pemphigus with characteristic clinical features, histopathological findings different from the convectional pemphigus, and immunological findings consistent with pemphigus.: Case report: We ...

    Abstract Introduction: Pemphigus herpetiformis is the rare variant of pemphigus with characteristic clinical features, histopathological findings different from the convectional pemphigus, and immunological findings consistent with pemphigus.
    Case report: We presented a 65-year-old woman with initial pruritus followed by pruritic urticarial papules and plaques, some with annular rings of tense vesicles on the periphery, on the trunk and extremities, with no mucous lesions. Histopathological examination demonstrated spongiosis and intraepidermal vesicles in the mid or subcorneal epidermis in some biopsy specimen, with neutrophil and eosinophil infiltrate. Direct immunoflorescent microscopy revealed intercellular IgG deposition, most prominent in the upper layers of epidermis. Indirect immunoflorescent microscopy showed intercellular binding of IgG autoantibodies in the patient’s sera. Initially the patient was threated with systemic corticosteroids and azathioprine, but dapson provided complete clinical remission.
    Conclusion: This entity was established 40 years ago, and around 100 patients have been reported worldwide. It is important to be aware of this particular form of pemphigus because clinical presentation, course of the disease and therapeutic approach are different from conventional forms of pemphigus.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Aged ; Autoantibodies/blood ; Azathioprine/therapeutic use ; Biomarkers/blood ; Biopsy ; Dapsone/therapeutic use ; Dermatitis Herpetiformis/drug therapy ; Dermatitis Herpetiformis/immunology ; Dermatitis Herpetiformis/pathology ; Female ; Fluorescent Antibody Technique ; Humans ; Immunoglobulin G/blood ; Pemphigus/drug therapy ; Pemphigus/immunology ; Pemphigus/pathology ; Remission Induction ; Skin/drug effects ; Skin/immunology ; Skin/pathology ; Treatment Outcome
    Chemical Substances Adrenal Cortex Hormones ; Autoantibodies ; Biomarkers ; Immunoglobulin G ; Dapsone (8W5C518302) ; Azathioprine (MRK240IY2L)
    Language English
    Publishing date 2016-10
    Publishing country Serbia
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 123795-0
    ISSN 0042-8450
    ISSN 0042-8450
    DOI 10.2298/VSP150617044S
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  6. Article ; Online: Annular lichenoid dermatitis of youth-Recurrent case of rare skin disease treated with cyclosporine.

    Stojkovic-Filipovic, Jelena / Lekic, Branislav / Brasanac, Dimitrije / Lalosevic, Jovan / Gajic-Veljic, Mirjana / Nikolic, Milos

    Dermatologic therapy

    2020  Volume 33, Issue 3, Page(s) e13285

    Abstract: Annular lichenoid dermatitis of youth (ALDY), first described in 2003, represents an uncommon entity whose etiopathogenesis is still debated. Futhermore, the optimal treatment for ALDY is yet to be established. We report a 9-year-old girl who presented ... ...

    Abstract Annular lichenoid dermatitis of youth (ALDY), first described in 2003, represents an uncommon entity whose etiopathogenesis is still debated. Futhermore, the optimal treatment for ALDY is yet to be established. We report a 9-year-old girl who presented with annular and oval erythematous lesions mostly on her trunk, with several lesions on the neck, groin, flanks, and upper extremities. The lesions had histological and immunohistochemical features characteristic for ALDY. Treatment with H1-antihistamines, topical corticosteroid, and UVB therapy was unsuccessful, while systemic treatment with cyclosporine induced complete remission.
    MeSH term(s) Administration, Cutaneous ; Adolescent ; Child ; Cyclosporine/therapeutic use ; Female ; Humans ; Lichenoid Eruptions/chemically induced ; Lichenoid Eruptions/diagnosis ; Lichenoid Eruptions/drug therapy ; Neurodermatitis ; Skin
    Chemical Substances Cyclosporine (83HN0GTJ6D)
    Language English
    Publishing date 2020-03-26
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13285
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  7. Article ; Online: Dermatoscopy of amelanotic and hypomelanotic melanoma.

    Stojkovic-Filipovic, Jelena / Kittler, Harald

    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG

    2014  Volume 12, Issue 6, Page(s) 467–472

    Abstract: Amelanotic melanoma is a subtype of cutaneous melanoma without pigment. The clinical diagnosis is challenging because it may mimic benign or malignant melanocytic and non-melanocytic neoplasms and inflammatory skin diseases. In synchrony with the ... ...

    Abstract Amelanotic melanoma is a subtype of cutaneous melanoma without pigment. The clinical diagnosis is challenging because it may mimic benign or malignant melanocytic and non-melanocytic neoplasms and inflammatory skin diseases. In synchrony with the improvement of the diagnosis of pigmented lesions, dermatoscopy may assist the clinician in the diagnosis of non-pigmented skin neoplasms in general and of amelanotic melanoma in particular. We have searched the literature to extract the most relevant dermatoscopic clues to diagnose amelanotic and hypomelanotic melanomas by dermatoscopy. In addition we present eight consecutive cases and discuss their clinical and dermatoscopic characteristics in the light of published data.
    MeSH term(s) Dermoscopy ; Diagnosis, Differential ; Humans ; Melanoma, Amelanotic/diagnosis ; Melanoma, Amelanotic/pathology ; Skin/pathology ; Skin Diseases/diagnosis ; Skin Diseases/pathology ; Skin Neoplasms/diagnosis ; Skin Neoplasms/pathology
    Language English
    Publishing date 2014-06
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2093479-8
    ISSN 1610-0387 ; 1610-0379
    ISSN (online) 1610-0387
    ISSN 1610-0379
    DOI 10.1111/ddg.12368
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  8. Article ; Online: Pemphigus herpetiformis - a case report of a rare form of pemphigus and review of the literature

    Stojković-Filipović Jelena / Lekić Branislav / Milčić Danijela / Milinković Mirjana V.

    Vojnosanitetski Pregled, Vol 73, Iss 10, Pp 967-

    2016  Volume 972

    Abstract: Introduction. Pemphigus herpetiformis is the rare variant of pemphigus with characteristic clinical features, histopathological findings different from the convectional pemphigus, and immunological findings consistent with pemphigus. Case report. We ... ...

    Abstract Introduction. Pemphigus herpetiformis is the rare variant of pemphigus with characteristic clinical features, histopathological findings different from the convectional pemphigus, and immunological findings consistent with pemphigus. Case report. We presented a 65-year-old woman with initial pruritus followed by pruritic urticarial papules and plaques, some with annular rings of tense vesicles on the periphery, on the trunk and extremities, with no mucous lesions. Histopathological examination demonstrated spongiosis and intraepidermal vesicles in the mid or subcorneal epidermis in some biopsy specimen, with neutrophil and eosinophil infiltrate. Direct immunoflorescent microscopy revealed intercellular IgG deposition, most prominent in the upper layers of epidermis. Indirect immunoflorescent microscopy showed intercellular binding of IgG autoantibodies in the patient’s sera. Initially the patient was threated with systemic corticosteroids and azathioprine, but dapson provided complete clinical remission. Conclusion. This entity was established 40 years ago, and around 100 patients have been reported worldwide. It is important to be aware of this particular form of pemphigus because clinical presentation, course of the disease and therapeutic approach are different from conventional forms of pemphigus.
    Keywords pemphigus ; rare diseases ; diagnosis ; drug therapy ; treatment outcome ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2016-01-01T00:00:00Z
    Publisher Military Health Department, Ministry of Defance, Serbia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Gianotti-Crosti syndrome associated with Ebstein-Barr virus and Parvovirus B-19 coinfection in a male adult: case report and review of the literature.

    Stojkovic-Filipovic, Jelena / Skiljevic, Dusan / Brasanac, Dimitrije / Medenica, Ljiljana

    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia

    2016  Volume 151, Issue 1, Page(s) 106–111

    Abstract: Gianotti-Crosti syndrome (GCS) is a self-limiting, mostly childhood-appearing, cutaneous eruption with characteristic symmetric areal distribution. The original cases, described by Gianotti in 1955, were associated with hepatitis B virus infection, but ... ...

    Abstract Gianotti-Crosti syndrome (GCS) is a self-limiting, mostly childhood-appearing, cutaneous eruption with characteristic symmetric areal distribution. The original cases, described by Gianotti in 1955, were associated with hepatitis B virus infection, but other viral and bacterial infections, as well as immunizations, have been implied in etiology of this condition. Adult cases are rare and have been reported almost exclusively in women. We present the case of a 20-year-old Caucasian man who had typical clinical presentation: monomorphic pale, pink-to-flesh - colored or erythematous papules and papulovesicles localized symmetrically over the extensor surfaces of the extremities, buttocks and the face; some lesions were detected on knees, elbows and palms, as well. Laboratory tests revealed slight bilirubin and alanine aminotransaminase elevation. Serology tests demonstrated antibodies against Epstein-Barr virus and parvovirus B-19. Histology of skin biopsy specimens revealed a vesicular dermatitis with perivascular lymphocytic infiltrate. Oral and topical corticosteroids and oral antihistamines led to complete resolution of lesions in 3 weeks. GCS is rare in adults, especially men. To the best of our knowledge, this is the fifth male adult case and the first with Parvovirus B-19 and EBV coinfection.
    MeSH term(s) Acrodermatitis/complications ; Acrodermatitis/drug therapy ; Acrodermatitis/pathology ; Adult ; Buttocks/pathology ; Coinfection ; Drug Therapy, Combination ; Epstein-Barr Virus Infections/complications ; Epstein-Barr Virus Infections/virology ; Extremities/pathology ; Face/pathology ; Glucocorticoids/therapeutic use ; Herpesvirus 4, Human/isolation & purification ; Histamine Antagonists/therapeutic use ; Humans ; Male ; Parvoviridae Infections/complications ; Parvoviridae Infections/virology ; Parvovirus B19, Human/isolation & purification ; Treatment Outcome
    Chemical Substances Glucocorticoids ; Histamine Antagonists
    Language English
    Publishing date 2016-02
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 604114-0
    ISSN 1827-1820 ; 0026-4741 ; 0392-0488
    ISSN (online) 1827-1820
    ISSN 0026-4741 ; 0392-0488
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  10. Article ; Online: Prepubertal onset of hidradenitis suppurativa in a girl: A case report and literature review.

    Stojkovic-Filipovic, Jelena M / Gajic-Veljic, Mirjana D / Nikolic, Milos

    Indian journal of dermatology, venereology and leprology

    2015  Volume 81, Issue 3, Page(s) 294–298

    MeSH term(s) Age Factors ; Child ; Female ; Groin/pathology ; Hidradenitis Suppurativa/diagnosis ; Hidradenitis Suppurativa/therapy ; Humans
    Language English
    Publishing date 2015-05
    Publishing country India
    Document type Case Reports ; Letter ; Review
    ZDB-ID 416068-x
    ISSN 0973-3922 ; 0019-5162 ; 0378-6323
    ISSN (online) 0973-3922
    ISSN 0019-5162 ; 0378-6323
    DOI 10.4103/0378-6323.152741
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