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  1. Article ; Online: Chronic intermittent intracranial hypertension caused by sinus pericranii complicated with transverse sinus stenosis in a child: A unique case report.

    Tang, Min / Sun, Mingming / Wei, Shihui / Xu, Quangang

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-03-04
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.02.062
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    Zs.B 2831: Show issues Location:
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  2. Article ; Online: Two new glycosides from the root bark of

    Kong, Chuihao / Wang, Kaidi / Sun, Lei / Qin, Shihui / Wang, Renzhong / Xu, Fengqing

    Natural product research

    2024  , Page(s) 1–7

    Abstract: Two new glycosides, ethyl- ...

    Abstract Two new glycosides, ethyl-
    Language English
    Publishing date 2024-03-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2024.2324372
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  3. Article ; Online: The effect of Benex minimally invasive extraction technique on the height of alveolar bone resorption and the integrity of the alveolar socket after extraction in immediate implantation without flap in anterior teeth.

    Dai, Binbin / Sun, Liming / Chen, Fangzhi / Zhan, Shihui

    Minerva pediatrics

    2023  Volume 75, Issue 4, Page(s) 639–642

    MeSH term(s) Humans ; Tooth ; Alveolar Bone Loss
    Language English
    Publishing date 2023-02-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.23.07166-5
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  4. Article ; Online: Case report: Overlapping anti-AMPAR encephalitis with anti-IgLON5 disease post herpes simplex virus encephalitis.

    Sun, Shihui / Ren, Jiafeng / Zhong, Zhao / Ma, Xuxia / Shang, Danqing / Su, Changjun / Zhao, Xianchao

    Frontiers in immunology

    2024  Volume 14, Page(s) 1329540

    Abstract: Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly linked to herpes simplex virus 1 (HSV-1) as the most frequently identified virus. The main areas ... ...

    Abstract Autoimmune encephalitis (AE) is the result of an autoimmune process that occurs as a rapidly advancing encephalopathy. Autoimmune encephalitis was commonly linked to herpes simplex virus 1 (HSV-1) as the most frequently identified virus. The main areas affected by this invasion are the temporal lobe, frontal lobe, and limbic system. Limbic encephalitis is a highly uncommon occurrence involving anti-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) encephalitis and anti-IgLON family member 5 (IgLON5) disease, both belonging to the rare category. As far as we know, this is the first report showing that a patient diagnosed with AMPAR encephalitis overlapped with anti-IgLON5 disease post herpes simplex virus encephalitis (HSE), which helps to broaden the range of this uncommon autoimmune disease. We recommend autoantibody testing in all patients with HSE, particularly those involving neurological relapses or progression.
    MeSH term(s) Humans ; Brain Diseases ; Cell Adhesion Molecules, Neuronal ; Encephalitis, Herpes Simplex/drug therapy ; Hashimoto Disease ; Herpesvirus 1, Human
    Chemical Substances Cell Adhesion Molecules, Neuronal ; IgLON5 protein, human
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1329540
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  5. Article ; Online: Targeting LEF1-mediated epithelial-mesenchymal transition reverses lenvatinib resistance in hepatocellular carcinoma.

    Li, Xinxiu / Su, Hongmeng / Tang, Wenqing / Shu, Shihui / Zhao, Luyu / Sun, Jinghan / Fan, Hong

    Investigational new drugs

    2024  Volume 42, Issue 2, Page(s) 185–195

    Abstract: Acquired resistance is a significant hindrance to clinical application of lenvatinib in unresectable hepatocellular carcinoma (HCC). Further in-depth investigation of resistance mechanisms can help to develop additional therapeutic strategies to overcome ...

    Abstract Acquired resistance is a significant hindrance to clinical application of lenvatinib in unresectable hepatocellular carcinoma (HCC). Further in-depth investigation of resistance mechanisms can help to develop additional therapeutic strategies to overcome or delay resistance. In our study, two lenvatinib-resistant (LR) HCC cell lines were established by treatment with gradient increasing concentration of lenvatinib, named Hep3B-LR and HepG2-LR. Interestingly, continuous lenvatinib treatment reinforced epithelial-mesenchymal transition (EMT), cell migration, and cell invasion. Gene set enrichment analysis (GSEA) enrichment analysis of RNA-sequencing from Hep3B-LR and corresponding parental cells revealed that activation of Wnt signaling pathway was involved in this adaptive process. Active β-catenin and its downstream target lymphoid enhancer binding factor 1 (LEF1) were significantly elevated in LR HCC cells, which promoted lenvatinib resistance through mediating EMT-related genes. Data analysis based on Gene Expression Omnibus (GEO) and the Cancer Genome Atlas Program (TCGA) databases suggests that LEF1, as a key regulator of EMT, was a novel molecular target linked to lenvatinib resistance and poor prognosis in HCC. Using a small-molecule specific inhibitor ICG001 and knocking down LEF1 showed that targeting LEF1 restored the sensitivity of LR HCC cells to lenvatinib. Our results uncover upregulation of LEF1 confers lenvatinib resistance by facilitating EMT, cell migration, and invasion of LR HCC cells, indicating that LEF1 is a novel therapeutic target for overcoming acquired lenvatinib resistance.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/metabolism ; Liver Neoplasms/drug therapy ; Liver Neoplasms/genetics ; Liver Neoplasms/metabolism ; Lymphoid Enhancer-Binding Factor 1/genetics ; Lymphoid Enhancer-Binding Factor 1/metabolism ; Cell Line, Tumor ; Epithelial-Mesenchymal Transition/genetics ; Gene Expression Regulation, Neoplastic ; Phenylurea Compounds ; Quinolines
    Chemical Substances lenvatinib (EE083865G2) ; Lymphoid Enhancer-Binding Factor 1 ; LEF1 protein, human ; Phenylurea Compounds ; Quinolines
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604895-x
    ISSN 1573-0646 ; 0167-6997
    ISSN (online) 1573-0646
    ISSN 0167-6997
    DOI 10.1007/s10637-024-01426-2
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    Zs.A 1823: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Visual Dissemination of Intangible Cultural Heritage Information Based on 3D Scanning and Virtual Reality Technology.

    Xu, Wulong / Sun, Xijie / Pan, Shihui

    publication RETRACTED

    Scanning

    2022  Volume 2022, Page(s) 8762504

    Abstract: In order to meet the needs of modern people for the acquisition of intangible cultural heritage information, the authors propose a research method that combines 3D scanning and virtual reality technology. Taking the production process of Xiuyu as an ... ...

    Abstract In order to meet the needs of modern people for the acquisition of intangible cultural heritage information, the authors propose a research method that combines 3D scanning and virtual reality technology. Taking the production process of Xiuyu as an example, using Unity3D virtual reality technology combined with a digital platform, 3D modeling of Xiuyu is carried out, so that people can view the intangible cultural heritage information intuitively. The experimental results show that after using this method, more than 60% of more than 1000 people surveyed in the questionnaire want to experience intangible cultural heritage. In a survey of visualization platforms conducted at the same time, 90% of users are willing to combine jade carving technology with 3D scanning virtual reality technology.
    MeSH term(s) Humans ; Technology ; Virtual Reality
    Language English
    Publishing date 2022-09-25
    Publishing country England
    Document type Journal Article ; Retracted Publication
    ZDB-ID 391900-6
    ISSN 1932-8745 ; 0161-0457
    ISSN (online) 1932-8745
    ISSN 0161-0457
    DOI 10.1155/2022/8762504
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    Zs.A 3871: Show issues Location:
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  7. Article ; Online: Influence of Waste Toner on Asphalt Binder

    Prince Igor Itoua / Daquan Sun / Ping Li / Shihui Shen

    Molecules, Vol 28, Iss 2794, p

    Chemical and Rheological Characterization

    2023  Volume 2794

    Abstract: The growing amount of waste toner (WT) has posed a significant environmental challenge. Meanwhile, researchers are interested in the feasibility of utilizing waste toner as an asphalt binder modifier because its primary chemical components (Styrene- ... ...

    Abstract The growing amount of waste toner (WT) has posed a significant environmental challenge. Meanwhile, researchers are interested in the feasibility of utilizing waste toner as an asphalt binder modifier because its primary chemical components (Styrene-acrylic copolymer and carbon black) are known to improve asphalt properties. The objective of this study was to evaluate the chemical and rheological properties of the waste-toner-modified asphalt binder and hence determine the suitability of integrating waste toner for asphalt modification. The waste-toner-modified asphalt (TMA) binders were produced by blending base asphalt with two types of waste toners of different gradation sizes. Microscopic tests such as x-ray fluorescence (XRF), attenuated total reflectance transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy with energy dispersive X-ray (SEM-EDS) and fluorescence microscope, as well as rheology tests such as multiple stress creep recovery (MSCR) tests, oscillation tests, and bending beam rheometer tests were performed. The FTIR results showed that there was a chemical reaction between waste toners and base asphalt binder. A fluorescence effect was observed on the binders produced with different toners used in this research. The binder modified with an optimal content of 8%WTs revealed better high and low-temperature properties. Additionally, 8%WTs used in this research could change the PG70-22 binder to PG76-22 binder. The rutting properties of asphalt material were improved for its improved elasticity. In addition, the 200-mesh TMA binders were desirable with respect to waste toner particle size. Overall, there is a benefit to using waste toner in the asphalt industry.
    Keywords modified asphalt binder ; waste toner ; rheology ; recycled material ; microscopic test ; Organic chemistry ; QD241-441
    Subject code 690
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
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  8. Article ; Online: Influence of Waste Toner on Asphalt Binder: Chemical and Rheological Characterization.

    Itoua, Prince Igor / Sun, Daquan / Li, Ping / Shen, Shihui

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 6

    Abstract: The growing amount of waste toner (WT) has posed a significant environmental challenge. Meanwhile, researchers are interested in the feasibility of utilizing waste toner as an asphalt binder modifier because its primary chemical components (Styrene- ... ...

    Abstract The growing amount of waste toner (WT) has posed a significant environmental challenge. Meanwhile, researchers are interested in the feasibility of utilizing waste toner as an asphalt binder modifier because its primary chemical components (Styrene-acrylic copolymer and carbon black) are known to improve asphalt properties. The objective of this study was to evaluate the chemical and rheological properties of the waste-toner-modified asphalt binder and hence determine the suitability of integrating waste toner for asphalt modification. The waste-toner-modified asphalt (TMA) binders were produced by blending base asphalt with two types of waste toners of different gradation sizes. Microscopic tests such as x-ray fluorescence (XRF), attenuated total reflectance transform infrared spectroscopy (ATR-FTIR), and scanning electron microscopy with energy dispersive X-ray (SEM-EDS) and fluorescence microscope, as well as rheology tests such as multiple stress creep recovery (MSCR) tests, oscillation tests, and bending beam rheometer tests were performed. The FTIR results showed that there was a chemical reaction between waste toners and base asphalt binder. A fluorescence effect was observed on the binders produced with different toners used in this research. The binder modified with an optimal content of 8%WTs revealed better high and low-temperature properties. Additionally, 8%WTs used in this research could change the PG70-22 binder to PG76-22 binder. The rutting properties of asphalt material were improved for its improved elasticity. In addition, the 200-mesh TMA binders were desirable with respect to waste toner particle size. Overall, there is a benefit to using waste toner in the asphalt industry.
    Language English
    Publishing date 2023-03-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28062794
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    Zs.MO 81: Show issues

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  9. Article ; Online: Clinical features and prognosis in the first episode of optic neuritis with COVID-19.

    Li, Yuyu / Sun, Mingming / Xu, Xintong / Chen, Biyue / Chen, Xiyun / Wang, Yuhang / Wei, Shihui / Xu, Quangang / Zhou, Huanfen

    Acta ophthalmologica

    2023  Volume 102, Issue 3, Page(s) e398–e401

    MeSH term(s) Humans ; COVID-19 ; Optic Neuritis/diagnosis ; Prognosis
    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2408333-1
    ISSN 1755-3768 ; 1755-375X
    ISSN (online) 1755-3768
    ISSN 1755-375X
    DOI 10.1111/aos.15789
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    Ul I Zs.90: Show issues Location:
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  10. Article ; Online: Human Health Risk Prediction Method of Regional Atmospheric Environmental Pollution Sources Based on PMF and PCA Analysis under Artificial Intelligence Cloud Model

    Shihui Zhang / Xinghua Sun / Naidi Liu / Jing Mi

    International Journal of Analytical Chemistry, Vol

    2022  Volume 2022

    Abstract: In order to solve the problem that atmospheric particulate matter has become the primary pollutant with serious harm and complex sources in recent years, this paper proposes an accurate identification method of pollution sources based on a receptor model ...

    Abstract In order to solve the problem that atmospheric particulate matter has become the primary pollutant with serious harm and complex sources in recent years, this paper proposes an accurate identification method of pollution sources based on a receptor model to obtain the contribution rate of each pollution source category. This method takes the 75-day measured environmental receptor data of an area under the artificial intelligence cloud model as the basic data, uses the normrnd () function to expand the receptor data, and uses the positive definite matrix factor analysis (PMF) and principal component analysis (PCA) models to verify the rationality of the data expansion. The results are as follows: the number of extended simulated receptor component spectra has a certain effect on the PCA analysis results, but the effect is smaller than the extended range. All relative errors are less than 14%, and the relative error is the smallest when the six simulated receptor component spectra are expanded, that is, the PCA analysis results of the expanded data are most consistent with the measured data; the number of expanded simulated receptor component spectra has a certain influence on the PMF analysis results. But the relative error is less than 40%. When extending the spectrum of six simulated receptor components, the relative error is the smallest, that is, the PMF analysis results of the extended data are most consistent with the measured data. It is proven that this method provides a more direct basis for the targeted treatment of pollution sources that are more harmful to human health.
    Keywords Analytical chemistry ; QD71-142
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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