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Article: Moyse Charas, Francesco Redi, the Viper and the Royal Society of London.

Catellani, Patrizia / Console, Renzo

2004 Volume 34, Issue 1, Page(s) 2–10

Abstract: We have described the 17th century dispute on the nature of the poison of the viper and its possible use as an antidote which arose between published in Britain at that time. We have also seen the reciprocal interest of Charas and members of the Royal ... ...

Abstract	We have described the 17th century dispute on the nature of the poison of the viper and its possible use as an antidote which arose between published in Britain at that time. We have also seen the reciprocal interest of Charas and members of the Royal Society in each other's work, and how Charas settled in England for a few years at the time of discrimination against the Huguenots in France. We prefer to leave any conclusions from this story to individual readers. However the dispute seems to be part of a transition from an animate view of the world to one where empirical methods do not appear to need to invoke 'spirits'. The story also seems to illustrate the limitation of experiments there can still be disagreement. If there is a the feeling that the subject is of interest, we can broaden it to cover scientific exchanges and connections between British and French Scholars in the field of pharmaceutical chemistry in the 17th and 18th centuries. At that time a number of pharmacists and scientists moved or corresponded between the two countries influencing one another. That was when modern chemistry gradually evolved out of traditional origins.
MeSH term(s)	Animals ; Animals, Poisonous ; France ; History, 17th Century ; Italy ; Pharmacists/history ; Physicians/history ; Portraits as Topic/history ; Science/history ; Snakes ; Societies/history
Language	English
Publishing date	2004-03
Publishing country	England
Document type	Biography ; Historical Article ; Journal Article
ZDB-ID	2915813-8
ISSN	0079-1393
ISSN	0079-1393
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: The Role of Geriatric Assessment in the Management of Diffuse Large B-Cell Lymphoma.

Merli, Francesco / Pozzi, Stefano / Catellani, Hillary / Barbieri, Emiliano / Luminari, Stefano

Cancers

2023 Volume 15, Issue 24

Abstract: The treatment choice for an older patient with diffuse large B-cell lymphoma (DLBCL) depends on many other factors in addition to age, which alone does not reflect the complexity of the aging process. Functional features and comorbidity incidence differ ... ...

Abstract	The treatment choice for an older patient with diffuse large B-cell lymphoma (DLBCL) depends on many other factors in addition to age, which alone does not reflect the complexity of the aging process. Functional features and comorbidity incidence differ not only between younger and older patients but also among older patients themselves. The comprehensive geriatric assessment (CGA) quickly evaluates fitness status by investigating the patient's different functional areas, degree of autonomy, and presence of comorbidities. Various tools are available to evaluate frailty; which assessment tool to use should be based on the clinical aim. The simplified geriatric assessment (sGA) from the elderly project by the Fondazione Italiana Linfomi, prospectively tested on the largest number of patients, categorizes patients as fit, unfit, or frail, with a decreasing rate of overall survival. The elderly prognostic index (EPI), which combines sGA and IPI scores and hemoglobin level, is the first prognostic score for older patients, with three risk groups for survival. Future GAs should consider new parameters, including sarcopenia, which appears to be inversely related to survival. New tools based on prospective studies can help physicians choose the best treatment in light of the individual patient's characteristics.
Language	English
Publishing date	2023-12-14
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2527080-1
ISSN	2072-6694
ISSN	2072-6694
DOI	10.3390/cancers15245845
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Article: Virulence Characteristics and Distribution of the Pathogen Listeria ivanovii in the Environment and in Food

Rossi, Franca / Giaccone, Valerio / Colavita, Giampaolo / Amadoro, Carmela / Pomilio, Francesco / Catellani, Paolo

Microorganisms

2022 Volume 10, Issue 8

Abstract: ... Listeria ... ...

Abstract	Listeria ivanovii
Language	English
Publishing date	2022-08-20
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms10081679
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Article: The Epidemiology of Shoulder Injuries in Water Polo Players: A Monocentric Descriptive Study on Clinical and Radiological Presentation.

Minelli, Marco / Longo, Umile Giuseppe / Ranieri, Riccardo / Pascucci, Federico / Giunti, Filippo / Conti, Marco / Catellani, Francesco / Castagna, Alessandro

Journal of clinical medicine

2024 Volume 13, Issue 7

Abstract: Water polo players' shoulders are exposed to repeated overhead and throwing motions as well as direct and indirect traumas. Shoulder injuries account for over half of all injuries sustained by water polo players. This is a monocentric descriptive ... ...

Abstract	Water polo players' shoulders are exposed to repeated overhead and throwing motions as well as direct and indirect traumas. Shoulder injuries account for over half of all injuries sustained by water polo players. This is a monocentric descriptive epidemiological study on the clinical and radiological presentation of a consecutive series of water polo players from January 2002 to September 2022. All patients underwent clinical and physical examinations and an MRI arthrogram. A total of 92 water polo players were included in this study. Fifty-three patients (57.6%) reported at least one previous shoulder instability episode; 100% of patients in this group were diagnosed with a capsulolabral complex lesion, and 88.7% of these players complained of subjective symptoms of shoulder instability (RR: 4.4). A total of 39 out of 92 patients (42.4%) did not report previous shoulder dislocation episodes; the mean age at presentation in this group was significantly higher than the mean age of the patients who experienced previous instability episodes (
Language	English
Publishing date	2024-03-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm13071951
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Article ; Online: Motion acquisition of gait characteristics one week after total hip arthroplasty: a factor analysis.

Cattaneo, Andrea / Ghidotti, Anna / Catellani, Francesco / Fiorentino, Gennaro / Vitali, Andrea / Regazzoni, Daniele / Rizzi, Caterina / Bombardieri, Emilio

Archives of orthopaedic and trauma surgery

2024

Abstract: Introduction: Clinical gait analysis can be used to evaluate the recovery process of patients undergoing total hip arthroplasty (THA). The postoperative walking patterns of these patients can be significantly influenced by the choice of surgical ... ...

Abstract	Introduction: Clinical gait analysis can be used to evaluate the recovery process of patients undergoing total hip arthroplasty (THA). The postoperative walking patterns of these patients can be significantly influenced by the choice of surgical approach, as each procedure alters distinct anatomical structures. The aim of this study is twofold. The first objective is to develop a gait model to describe the change in ambulation one week after THA. The secondary goal is to describe the differences associated with the surgical approach. Materials and methods: Thirty-six patients undergoing THA with lateral (n = 9), anterior (n = 15), and posterior (n = 12) approaches were included in the study. Walking before and 7 days after surgery was recorded using a markerless motion capture system. Exploratory Factor Analysis (EFA), a data reduction technique, condensed 21 spatiotemporal gait parameters to a smaller set of dominant variables. The EFA-derived gait domains were utilized to study post-surgical gait variations and to compare the post-surgical gait among the three groups. Results: Four distinct gait domains were identified. The most pronounced variation one week after surgery is in the Rhythm (gait cycle time: Conclusions: This study identified a four-component gait model specific to THA patients. The results showed that patients after THA have longer stride time but shorter stride length, wider base of support, and longer stance time, although the posterior group had a statistically significant shorter stance time than the others. The findings of this research have the potential to simplify the reporting of gait outcomes, reduce redundancy, and inform targeted interventions in regards to specific gait domains.
Language	English
Publishing date	2024-03-14
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80407-1
ISSN	1434-3916 ; 0003-9330 ; 0344-8444
ISSN (online)	1434-3916
ISSN	0003-9330 ; 0344-8444
DOI	10.1007/s00402-024-05245-1
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Article ; Online: Medium-term follow up of active surveillance for early prostate cancer at a non-academic institution.

Leni, Riccardo / Roscigno, Marco / Barzaghi, Paolo / La Croce, Giovanni / Catellani, Michele / Saccà, Antonino / de Angelis, Mario / Montorsi, Francesco / Briganti, Alberto / Da Pozzo, Luigi Filippo

BJU international

2024 Volume 133, Issue 5, Page(s) 614–621

Abstract: Objectives: To report oncological outcomes of active surveillance (AS) at a single non-academic institution adopting the standardised Prostate Cancer Research International Active Surveillance (PRIAS) protocol.: Patients and methods: Competing risk ... ...

Abstract	Objectives: To report oncological outcomes of active surveillance (AS) at a single non-academic institution adopting the standardised Prostate Cancer Research International Active Surveillance (PRIAS) protocol. Patients and methods: Competing risk analyses estimated the incidence of overall mortality, metastases, conversion to treatment, and grade reclassification. The incidence of reclassification and adverse pathological findings at radical prostatectomy were compared between patients fulfilling all PRIAS inclusion criteria vs those not fulfilling at least one. Results: We analysed 341 men with Grade Group 1 prostate cancer (PCa) followed on AS between 2010 and 2022. There were no PCa deaths, two patients developed distant metastases and were alive at the end of the study period. The 10-year cumulative incidence of metastases was 1.9% (95% confidence interval [CI] 0.33-6.4%). A total of 111 men were reclassified, and 127 underwent definitive treatment. Men not fulfilling at least one PRIAS inclusion criteria (n = 43) had a higher incidence of reclassification (subdistribution hazards ratio 1.73, 95% CI 1.07-2.81; P = 0.03), but similar rates of adverse pathological findings at radical prostatectomy. Conclusion: Metastases in men on AS at a non-academic institution are as rare as those reported in established international cohorts. Men followed without stringent inclusion criteria should be counselled about the higher incidence of reclassification and reassured they can expect rates of adverse pathological findings comparable to those fulfilling all criteria. Therefore, AS should be proposed to all men with low-grade PCa regardless of whether they are followed at academic institutions or smaller community hospitals.
MeSH term(s)	Humans ; Male ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/surgery ; Prostatic Neoplasms/therapy ; Prostatic Neoplasms/mortality ; Watchful Waiting ; Middle Aged ; Aged ; Follow-Up Studies ; Prostatectomy ; Neoplasm Grading ; Neoplasm Metastasis
Language	English
Publishing date	2024-01-22
Publishing country	England
Document type	Journal Article
ZDB-ID	1462191-5
ISSN	1464-410X ; 1464-4096 ; 1358-8672
ISSN (online)	1464-410X
ISSN	1464-4096 ; 1358-8672
DOI	10.1111/bju.16259
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Article: Real-Life Experience of Continuously Infused Ceftolozane/Tazobactam in Patients with Bronchiectasis and Multidrug-Resistant

Venuti, Francesco / Gaviraghi, Alberto / De Nicolò, Amedeo / Stroffolini, Giacomo / Longo, Bianca Maria / Di Vincenzo, Alessia / Ranzani, Fabio Antonino / Quaranta, Matilde / Romano, Francesca / Catellani, Eleonora / Marchiaro, Carlotta / Cinnirella, Giacoma / D'Avolio, Antonio / Bonora, Stefano / Calcagno, Andrea

Antibiotics (Basel, Switzerland)

2023 Volume 12, Issue 7

Abstract: 1) Background: Ceftolozane/tazobactam (C/T) is a novel β-lactam/β-lactamase inhibitor with excellent activity against the multidrug-resistant (MDR) ...

Abstract	(1) Background: Ceftolozane/tazobactam (C/T) is a novel β-lactam/β-lactamase inhibitor with excellent activity against the multidrug-resistant (MDR)
Language	English
Publishing date	2023-07-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2681345-2
ISSN	2079-6382
ISSN	2079-6382
DOI	10.3390/antibiotics12071214
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Article: Successful treatment with benralizumab in a patient with eosinophilic granulomatosis with polyangiitis refractory to mepolizumab.

Menzella, Francesco / Galeone, Carla / Ghidoni, Giulia / Ruggiero, Patrizia / Capobelli, Silvia / Simonazzi, Anna / Catellani, Chiara / Scelfo, Chiara / Livrieri, Francesco / Facciolongo, Nicola

Multidisciplinary respiratory medicine

2021 Volume 16, Issue 1, Page(s) 779

Abstract: Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by necrotizing eosinophilic granulomatous inflammation that frequently involves the respiratory tract (90% of cases). Asthma in EGPA is systematically severe and often ... ...

Abstract	Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by necrotizing eosinophilic granulomatous inflammation that frequently involves the respiratory tract (90% of cases). Asthma in EGPA is systematically severe and often refractory to common treatment, it is corticosteroid resistant and can often anticipate the onset of systemic vasculitis by many years. A release of cytokines necessary for the activation, maturation and survival of eosinophils, such as IL-4, IL-5 and IL-13 occurs in the activated Th-2 phenotype. In particular, IL-5 level is high in active EGPA and its inhibition has become a key therapeutic target. Oral glucocorticoids (OCS) are effective treatment options but unfortunately, frequent relapses occur in many patients and they lead to frequent side effects. As for now, there are currently no official recommendations on doses and treatment schedules in the management of EGPA. Case presentation: In this article, we describe the case of a man with EGPA, severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP), with poor asthma and CRSwNP control despite OCS and mepolizumab treatment. Respiratory and vasculitis symptoms improved markedly after therapeutic switch to benralizumab. During the treatment, in addition to clinical effects, we witnessed a depletion of blood eosinophils, as well as an improvement in both pulmonary function tests, CT scan and skin lesions present initially. Conclusions: While there are many studies confirming the efficacy of benralizumab in EGPA, the most interesting aspect of our report is that efficacy was confirmed in a patient previously unresponsive to mepolizumab, known to be effective in EGPA.
Language	English
Publishing date	2021-06-24
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2677839-7
ISSN	2049-6958 ; 1828-695X
ISSN (online)	2049-6958
ISSN	1828-695X
DOI	10.4081/mrm.2021.779
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Article: Artificial Intelligence in the Advanced Diagnosis of Bladder Cancer-Comprehensive Literature Review and Future Advancement.

Diagnostics (Basel, Switzerland)

2023 Volume 13, Issue 13

Abstract: Artificial intelligence is highly regarded as the most promising future technology that will have a great impact on healthcare across all specialties. Its subsets, machine learning, deep learning, and artificial neural networks, are able to automatically ...

Abstract	Artificial intelligence is highly regarded as the most promising future technology that will have a great impact on healthcare across all specialties. Its subsets, machine learning, deep learning, and artificial neural networks, are able to automatically learn from massive amounts of data and can improve the prediction algorithms to enhance their performance. This area is still under development, but the latest evidence shows great potential in the diagnosis, prognosis, and treatment of urological diseases, including bladder cancer, which are currently using old prediction tools and historical nomograms. This review focuses on highly significant and comprehensive literature evidence of artificial intelligence in the management of bladder cancer and investigates the near introduction in clinical practice.
Language	English
Publishing date	2023-07-07
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662336-5
ISSN	2075-4418
ISSN	2075-4418
DOI	10.3390/diagnostics13132308
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Article ; Online: Radiotherapy in the era of COVID-19.

Lancia, Andrea / Bonzano, Elisabetta / Bottero, Marta / Camici, Marta / Catellani, Francesco / Ingrosso, Gianluca

Expert review of anticancer therapy

2020 Volume 20, Issue 8, Page(s) 625–627

MeSH term(s)	Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Dose Fractionation, Radiation ; Expert Testimony ; Humans ; Neoplasms/radiotherapy ; Neoplasms/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Practice Guidelines as Topic/standards ; Radiotherapy/standards ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-07-07
Publishing country	England
Document type	Editorial
ZDB-ID	2112544-2
ISSN	1744-8328 ; 1473-7140
ISSN (online)	1744-8328
ISSN	1473-7140
DOI	10.1080/14737140.2020.1785290
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