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  1. Article ; Online: Psychometric Evaluation of the Revised Iowa Pain Thermometer (IPT-R) in a Sample of Diverse Cognitively Intact and Impaired Older Adults: A Pilot Study.

    Ware, Laurie Jowers / Herr, Keela A / Booker, Staja Star / Dotson, Kelley / Key, Jennifer / Poindexter, Norma / Pyles, Gia / Siler, Bobbie / Packard, Abbot

    Pain management nursing : official journal of the American Society of Pain Management Nurses

    2020  Volume 16, Issue 4, Page(s) 475–482

    Abstract: ... Thermometer (IPT-R) to evaluate the psychometric properties of the IPT-R and to determine patient preference ... for a self-report pain assessment tool. A descriptive, correlational design was employed. The IPT-R was compared ... scales (IPT-R, IPT, and NRS) presented in random order. Participants were asked to identify the tool ...

    Abstract Self-report pain assessment tools are commonly used in clinical settings to determine patients' pain intensity. The Iowa Pain Thermometer (IPT) is a tool that was developed for research, but also can be used in clinical settings. However, its utility in clinical settings is challenging because it uses a 13-point scale (0-12 scale) that does not align with common electronic pain scoring metrics. Therefore, this study evaluated the psychometric properties of an 11-point (0-10 scale) adaptation of the Iowa Pain Thermometer (IPT-R) to evaluate the psychometric properties of the IPT-R and to determine patient preference for a self-report pain assessment tool. A descriptive, correlational design was employed. The IPT-R was compared with the original IPT and a numeric rating scale (NRS). This study was conducted in the southeastern United States with 75 adults ranging in age from 65-95 years with varying levels of cognition. Participants were primarily representative of black and white backgrounds. Participants were asked to rate current pain, worst pain during the past week, and reassessment of current pain after 10-minute intervals using three scales (IPT-R, IPT, and NRS) presented in random order. Participants were asked to identify the tool preferred (the easiest to use and that best represented their pain intensity). Spearman-rank correlations were performed to determine convergent validity and test-retest reliability. Based on the results of this preliminary study, the IPT-R has good validity and reliability. The participants in this sample preferred the IPT-R over the original IPT (0-12 scale) and the traditional NRS (0-10 scale). Clinicians may consider using this tool with diverse older patients to assess pain intensity.
    MeSH term(s) Aged ; Aged, 80 and over ; Case-Control Studies ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/psychology ; Female ; Humans ; Male ; Pain/complications ; Pain/diagnosis ; Pain/psychology ; Pain Measurement/instrumentation ; Pain Measurement/methods ; Patient Preference ; Pilot Projects ; Psychometrics ; Reproducibility of Results ; Sensitivity and Specificity
    Language English
    Publishing date 2020-06-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2213260-0
    ISSN 1532-8635 ; 1524-9042
    ISSN (online) 1532-8635
    ISSN 1524-9042
    DOI 10.1016/j.pmn.2014.09.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Long-chain alkanes and ent-labdane-type diterpenes from Gymnosperma glutinosum with cytotoxic activity against the murine lymphoma L5178Y-R.

    Gomez-Flores, R / Quintanilla-Licea, R / Verde-Star, M J / Morado-Castillo, R / Vázquez-Díaz, D / Tamez-Guerra, R / Tamez-Guerra, P / Rodríguez-Padilla, C

    Phytotherapy research : PTR

    2012  Volume 26, Issue 11, Page(s) 1632–1636

    Abstract: ... in vivo L5178Y-R lymphoma murine model. The present study was carried out to isolate and identify ... subfractions was assessed in vitro against L5178Y-R lymphoma cells. Structure elucidation of the active ... and concentration-dependent 20% to 56% cytotoxicity against L5178Y-R cells at concentrations ranging ...

    Abstract The antitumor potential of Gymnosperma glutinosum was previously reported using the in vitro and in vivo L5178Y-R lymphoma murine model. The present study was carried out to isolate and identify the cytotoxic compounds present in the Gymnosperma glutinosum leaf hexane extract. Gymnosperma glutinosum was collected in the semi-arid region of Escobedo, State of Nuevo León, México, but it is commonly found in northeastern Mexico; it is traditionally used as a treatment for diarrhea, ulcers and rheumatism. G. glutinosum leaves were extracted with hexane and further fractioned and subfractioned over silica gel by gradient elution with hexane, chloroform, ethyl acetate and methanol. The cytotoxicity of fractions and subfractions was assessed in vitro against L5178Y-R lymphoma cells. Structure elucidation of the active compounds was determined by spectroscopic methods. Fractions and subfractions showed significant (p < 0.05) and concentration-dependent 20% to 56% cytotoxicity against L5178Y-R cells at concentrations ranging from 7.8 µg/mL to 500 µg/mL. The bioassay-guided fractionation of the hexane extract resulted in the isolation and identification of the alkane hentriacontane and the diterpene ent-labd-7-en-13S,14R,15-triol as the metabolites responsible for the activity.
    MeSH term(s) Alkanes/chemistry ; Alkanes/isolation & purification ; Alkanes/pharmacology ; Animals ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/isolation & purification ; Antineoplastic Agents, Phytogenic/pharmacology ; Asteraceae/chemistry ; Cell Line, Tumor ; Diterpenes/chemistry ; Diterpenes/isolation & purification ; Diterpenes/pharmacology ; Lymphoma/pathology ; Mexico ; Mice ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Plant Leaves/chemistry
    Chemical Substances Alkanes ; Antineoplastic Agents, Phytogenic ; Diterpenes ; Plant Extracts
    Language English
    Publishing date 2012-11
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.4625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Long‐chain Alkanes and ent‐Labdane‐type Diterpenes from Gymnosperma glutinosum with Cytotoxic Activity Against the Murine Lymphoma L5178Y‐R

    Gomez‐Flores, R / Quintanilla‐Licea, R / Verde‐Star, M. J / Morado‐Castillo, R / Vázquez‐Díaz, D / Tamez‐Guerra, R / Tamez‐Guerra, P / Rodríguez‐Padilla, C

    Phytotherapy research. 2012 Nov., v. 26, no. 11

    2012  

    Abstract: ... in vivo L5178Y‐R lymphoma murine model. The present study was carried out to isolate and identify ... subfractions was assessed in vitro against L5178Y‐R lymphoma cells. Structure elucidation of the active ... and concentration‐dependent 20% to 56% cytotoxicity against L5178Y‐R cells at concentrations ranging ...

    Abstract The antitumor potential of Gymnosperma glutinosum was previously reported using the in vitro and in vivo L5178Y‐R lymphoma murine model. The present study was carried out to isolate and identify the cytotoxic compounds present in the Gymnosperma glutinosum leaf hexane extract. Gymnosperma glutinosum was collected in the semi‐arid region of Escobedo, State of Nuevo León, México, but it is commonly found in northeastern Mexico; it is traditionally used as a treatment for diarrhea, ulcers and rheumatism. G. glutinosum leaves were extracted with hexane and further fractioned and subfractioned over silica gel by gradient elution with hexane, chloroform, ethyl acetate and methanol. The cytotoxicity of fractions and subfractions was assessed in vitro against L5178Y‐R lymphoma cells. Structure elucidation of the active compounds was determined by spectroscopic methods. Fractions and subfractions showed significant (p < 0.05) and concentration‐dependent 20% to 56% cytotoxicity against L5178Y‐R cells at concentrations ranging from 7.8 µg/mL to 500 µg/mL. The bioassay‐guided fractionation of the hexane extract resulted in the isolation and identification of the alkane hentriacontane and the diterpene ent‐labd‐7‐en‐13S,14R,15‐triol as the metabolites responsible for the activity.
    Keywords animal models ; chloroform ; cytotoxicity ; diterpenoids ; fractionation ; hexane ; leaves ; lymphoma ; methanol ; mice ; silica gel ; Mexico
    Language English
    Dates of publication 2012-11
    Size p. 1632-1636.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    ZDB-ID 639136-9
    ISSN 1099-1573 ; 0951-418X
    ISSN (online) 1099-1573
    ISSN 0951-418X
    DOI 10.1002/ptr.4625
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Bibliometric Analysis of Spinopelvic Alignment in Total Hip Arthroplasty.

    Harrer, Samantha / Magnuson, Justin A / Toci, Gregory R / Star, Andrew M / Saxena, Arjun

    Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews

    2023  Volume 7, Issue 6

    Abstract: Introduction: Postoperative dislocation of unclear etiology remains a concern after total hip arthroplasty (THA). Interest is growing in the importance of spinopelvic alignment on stability in THA. The purpose of this study was to analyze publication ... ...

    Abstract Introduction: Postoperative dislocation of unclear etiology remains a concern after total hip arthroplasty (THA). Interest is growing in the importance of spinopelvic alignment on stability in THA. The purpose of this study was to analyze publication trends, areas of interest, and future research direction of spinopelvic alignment in THA.
    Methods: Articles on the topic of spinopelvic alignment in THA published between 1990 and 2022 were obtained through Web of Science Core Collection of Clarivate Analytics (WSCCA). Results were screened by title, abstract, and full text. The inclusion criterion was English-language peer-reviewed journal publications on the clinical topic of spinopelvic alignment in THA. Bibliometric software was used to characterize publication trends.
    Results: We screened 1,211 articles, yielding 132 meeting the inclusion criterion. From 1990 to 2022, published articles have steadily increased, peaking in 2021. Countries that have been the most productive in contributions to research are those in which THA is the most prevalent. Our analysis of keyword frequency showed increasing interest in "pelvic tilt," "anteversion," and "acetabular component" position.
    Conclusion: Our study identified that increasing attention is being given to spinopelvic mobility and PT in the setting of THA. The United States and France produced the most studies related to spinopelvic alignment.
    MeSH term(s) Humans ; Arthroplasty, Replacement, Hip/adverse effects ; Acetabulum/surgery ; Joint Dislocations/etiology ; Joint Dislocations/surgery ; Posture ; Postoperative Complications
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2898328-2
    ISSN 2474-7661 ; 1067-151X
    ISSN (online) 2474-7661
    ISSN 1067-151X
    DOI 10.5435/JAAOSGlobal-D-22-00182
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Diagnostics of Tuberculosis with Single-Walled Carbon Nanotube-Based Field-Effect Transistors.

    Wang, Jieyu / Shao, Wenting / Liu, Zhengru / Kesavan, Ganesh / Zeng, Zidao / Shurin, Michael R / Star, Alexander

    ACS sensors

    2024  Volume 9, Issue 4, Page(s) 1957–1966

    Abstract: Tuberculosis (TB) is still threatening millions of people's lives, especially in developing countries. One of the major factors contributing to the ongoing epidemic of TB is the lack of a fast, efficient, and inexpensive diagnostic strategy. In this work, ...

    Abstract Tuberculosis (TB) is still threatening millions of people's lives, especially in developing countries. One of the major factors contributing to the ongoing epidemic of TB is the lack of a fast, efficient, and inexpensive diagnostic strategy. In this work, we developed a semiconducting single-walled carbon nanotube (SWCNT)-based field-effect transistor (FET) device functionalized with anti-
    MeSH term(s) Nanotubes, Carbon/chemistry ; Transistors, Electronic ; Tuberculosis/diagnosis ; Tuberculosis/blood ; Biosensing Techniques/methods ; Biosensing Techniques/instrumentation ; Humans ; Mycobacterium tuberculosis/isolation & purification ; Antigens, Bacterial/immunology ; Antigens, Bacterial/blood ; Antigens, Bacterial/analysis ; Limit of Detection ; Acyltransferases ; Bacterial Proteins
    Chemical Substances Nanotubes, Carbon ; Antigens, Bacterial ; antigen 85B, Mycobacterium tuberculosis (EC 2.3.1.-) ; Acyltransferases (EC 2.3.-) ; Bacterial Proteins
    Language English
    Publishing date 2024-03-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.3c02694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Chinese parents' support of preschoolers' mathematical development.

    Yang, Qianru Tiffany / Star, Jon R / Harris, Paul L / Rowe, Meredith L

    Journal of experimental child psychology

    2023  Volume 236, Page(s) 105753

    Abstract: Research has documented the critical role played by the early home environment in children's mathematical development in Western contexts. Yet little is known about how Chinese parents support their preschoolers' development of math skills. The Chinese ... ...

    Abstract Research has documented the critical role played by the early home environment in children's mathematical development in Western contexts. Yet little is known about how Chinese parents support their preschoolers' development of math skills. The Chinese context is of particular interest because Chinese children outperform their Western counterparts in math, even early in development. The current study sought to fill this gap by examining a sample of 90 families of 4- and 5-year-olds from mainland China. Parental support-as measured by the frequency of parent-child engagement in home activities as well as parent number talk-and parents' role in children's numeracy skills were investigated. Results indicate wide variation among parents in both types of support. Frequency of engagement in formal numeracy activities, including counting objects and reading number story books, was related to children's knowledge of cardinality. A principal components analysis did not identify informal numeracy activities as a distinct home activity component, likely due to the infrequent occurrences of game-like numeracy activities among the Chinese families. Instead, a structured activity component emerged (e.g., playing musical instruments) and was positively related to children's arithmetic skills. Diversity, but not quantity, of parent number talk was related to children's symbolic magnitude understanding. The distinctive relationships between specific parental measures and child outcomes speak to the need for nuanced identification of home environment factors that are beneficial to particular math competencies. The findings also suggest cultural variations in the mechanisms that support children's mathematical development, highlighting the merits of investigating this topic in non-Western contexts.
    MeSH term(s) Humans ; Child, Preschool ; Reading ; Parent-Child Relations ; Mathematics ; Parents ; China
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218137-x
    ISSN 1096-0457 ; 0022-0965
    ISSN (online) 1096-0457
    ISSN 0022-0965
    DOI 10.1016/j.jecp.2023.105753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Consistency of Acetabular Height in Sequential Bilateral Total Hip Arthroplasty.

    Kong, Qingwu / Abdelfadeel, Walaa / Hwang, Rock / Saxena, Arjun / Star, Andrew

    Arthroplasty today

    2022  Volume 14, Page(s) 100–104

    Abstract: Background: Achieving appropriate leg length after surgery remains a concern for surgeons performing total hip arthroplasty (THA). The focus of surgeons trying to equalize leg length has been primarily on positioning of the femoral implant. This study ... ...

    Abstract Background: Achieving appropriate leg length after surgery remains a concern for surgeons performing total hip arthroplasty (THA). The focus of surgeons trying to equalize leg length has been primarily on positioning of the femoral implant. This study evaluates the impact of acetabular height on leg length and its impact on femoral component choices during THA.
    Methods: We reviewed standing pelvic radiographs of 100 patients who underwent staged bilateral THA by a single surgeon from 2016 to 2019. Leg length discrepancies and acetabular heights were determined from preoperative and postoperative radiographs. The difference between the first and second operative hips was compared at each stage of the procedures. Results were analyzed using paired t-tests.
    Results: There is a significant increase in mean leg length and acetabular height after both the first and second stages of the procedure. Although there was a small change in average acetabular height for each procedure, height increased or decreased by greater than 5 mm in 44 of 200 cases. Comparing left to right hips after the second surgery disclosed no statistically significant differences in acetabular height or leg length.
    Conclusion: Acetabular height and leg length changes with each stage of the procedure in sequential bilateral THA. In almost 25% of cases, the acetabular height changed by more than 5 mm. This has significant implications and needs to be considered during preoperative planning as well as operative decision-making. To account for these differences, a THA may require intraoperative acetabular assessment and changes in femoral positioning and sizing to achieve the optimal leg length.
    Language English
    Publishing date 2022-03-02
    Publishing country United States
    Document type Journal Article
    ISSN 2352-3441
    ISSN 2352-3441
    DOI 10.1016/j.artd.2022.01.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Dapagliflozin

    Arbel, Ronen / Azab, Abed N / Oberoi, Mansi / Aboalhasan, Enis / Star, Artyom / Elhaj, Khaled / Khalil, Fouad / Alnsasra, Hilmi

    Frontiers in pharmacology

    2024  Volume 15, Page(s) 1357673

    Abstract: Background and aim: Heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of heart failure (HF) hospitalizations and cardiovascular death (CVD). Both dapagliflozin and sacubitril-valsartan have recently shown ... ...

    Abstract Background and aim: Heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of heart failure (HF) hospitalizations and cardiovascular death (CVD). Both dapagliflozin and sacubitril-valsartan have recently shown convincing reductions in the combined risk of CVD and HF hospitalizations in patients with HF and mildly reduced ejection fraction (HFmrEF) or HFpEF. We aimed to investigate the cost-per-outcome implications of dapagliflozin vs sacubitril-valsartan in the treatment of HFmrEF or HFpEF patients.
    Methods: We compared the annualized cost needed to treat (CNT) to prevent the composite outcome of total HF hospitalizations and CVD with dapagliflozin or sacubitril-valsartan. The CNT was estimated by multiplying the annualized number needed to treat (aNNT) by the annual cost of therapy. The aNNT was calculated based on data collected from the DELIVER trial for dapagliflozin and a pooled analysis of the PARAGLIDE-HF and PARAGON-HF trials for sacubitril-valsartan. Costs were based on 2022 US prices. Scenario analyses were performed to attenuate the differences in the studies' populations.
    Results: The aNNT with dapagliflozin in DELIVER was 30 (95% confidence interval [CI]: 21-62)
    Conclusion: Dapagliflozin provides a better monetary value than sacubitril-valsartan in preventing the composite outcome of total HF hospitalizations and CVD among patients with HFmrEF or HFpEF.
    Language English
    Publishing date 2024-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2024.1357673
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Article ; Online: UMS labs ready to help state Health Dept test for Covid-19

    The Star, UNSPECIFIED

    2020  

    Keywords HT Communities. Classes. Races ; R Medicine (General) ; covid19
    Publishing date 2020-04-02
    Publisher The Star
    Publishing country my
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Phonological awareness and RAN contribute to Chinese reading and arithmetic for different reasons.

    Yang, Xiujie / Star, Jon R / Zhu, Xiangyi / Wang, Rong / Zhang, Yan / Tong, Jiajin / He, Zhonghui

    Cognitive processing

    2024  

    Abstract: The present study investigated how phonological awareness and rapid automatized naming (hereafter, RAN), simultaneously contributed to Chinese reading and arithmetic fluency. Specifically, we proposed a new hypothesized mechanism that processing speed ... ...

    Abstract The present study investigated how phonological awareness and rapid automatized naming (hereafter, RAN), simultaneously contributed to Chinese reading and arithmetic fluency. Specifically, we proposed a new hypothesized mechanism that processing speed would mediate the relations of RAN with Chinese reading and arithmetic fluency. One hundred and forty-five Chinese children at the fifth grade were administered with a battery of measures, including three phonological processing measures, character reading, and whole number computation, as well as nonverbal IQ, and vocabulary knowledge. Path analyses revealed that phonological awareness and RAN were uniquely related to character reading and arithmetic fluency, while phonological memory was not significantly correlated to either character reading or arithmetic fluency, after controlling for age, nonverbal IQ, and vocabulary knowledge. Further analysis indicated that processing speed demonstrated a mediating effect on the importance of RAN in character reading, rather than in arithmetic fluency. Results underscore the potential importance of phonological awareness and RAN in character reading and arithmetic fluency, and the mediating role of processing speed in RAN to promote Chinese character reading fluency.
    Language English
    Publishing date 2024-03-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2075054-7
    ISSN 1612-4790 ; 1612-4782
    ISSN (online) 1612-4790
    ISSN 1612-4782
    DOI 10.1007/s10339-024-01184-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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