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  1. Article ; Online: Clinical guideline highlights for the hospitalist: Pediatric direct hospital admission.

    Nassetta, Lauren B / Marlin, Brittany / Scalici, Paul

    Journal of hospital medicine

    2023  Volume 18, Issue 12, Page(s) 1120–1122

    Abstract: Guideline title: Direct Admission to the Hospital for Children in the United States RELEASE DATE: March 3, 2023 PRIOR VERSION(S): n/a DEVELOPER: American Academy of Pediatrics, Committee on Hospital Care FUNDING SOURCE: American Academy of Pediatrics ... ...

    Abstract Guideline title: Direct Admission to the Hospital for Children in the United States RELEASE DATE: March 3, 2023 PRIOR VERSION(S): n/a DEVELOPER: American Academy of Pediatrics, Committee on Hospital Care FUNDING SOURCE: American Academy of Pediatrics TARGET POPULATION: Children who are potential candidates for direct hospital admission.
    MeSH term(s) Child ; Humans ; United States ; Hospitalists ; Hospitalization ; Hospitals, Pediatric
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.1002/jhm.13202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Don't Go: Examining the Relationships Between Meaning, Work Environment and Turnover Intention Across the Entire Healthcare Team.

    Meese, Katherine A / Boitet, Laurence M / Sweeney, Katherine L / Gorman, C Allen / Nassetta, Lauren B / Patel, Nisha / Rogers, David A

    Journal of multidisciplinary healthcare

    2024  Volume 17, Page(s) 353–366

    Abstract: Introduction: Healthcare workers tend to have a strong sense of altruism in their work, which may be protective against turnover despite poor working conditions. Due to the increased distress noted during the pandemic, the challenges of working in ... ...

    Abstract Introduction: Healthcare workers tend to have a strong sense of altruism in their work, which may be protective against turnover despite poor working conditions. Due to the increased distress noted during the pandemic, the challenges of working in healthcare and changing attitudes about work may have surpassed the protective effect of meaning and purpose in work. This study empirically examines perceived meaning in work, and specific work-related factors that contribute to employees' intent to stay and to recommend working at the organization to others as COVID-19 transitions from a pandemic to endemic phase.
    Methods: Data from a survey of 4451 clinical and non-clinical healthcare workers were analyzed using regression and dominance analyses to identify specific predictors of turnover intention and net promoter score.
    Results: The variables that explained the greatest contribution to variance in turnover intention from highest to lowest were burnout, trust and confidence in senior leadership, perceived organizational support, sense of belonging, and sense of recognition. The variables that explained the greatest overall contribution to variance for net promoter score from highest to lowest were perceived organizational support, trust and confidence in senior leadership, resource availability, sense of recognition, and sense of belonging. While meaning in work was associated with turnover intent, organizational and team level factors such as trust and belonging were more predictive of the outcomes.
    Discussion: While meaning and purpose are important job resources, they are not sufficient to retain employees in the absence of trust, organizational support, belonging, recognition and access to necessary resources. Leaders must seek to foster environments that support trust, belonging and recognition in their retention efforts.
    Language English
    Publishing date 2024-01-23
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2453343-9
    ISSN 1178-2390
    ISSN 1178-2390
    DOI 10.2147/JMDH.S437816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Still Exhausted: The Role of Residual Caregiving Fatigue on Women in Medicine and Science Across the Pipeline.

    Meese, Katherine A / Boitet, Laurence M / Sweeney, Katherine L / Nassetta, Lauren / Mugavero, Michael / Hidalgo, Bertha / Reamey, Rebecca / Rogers, David A

    Journal of medical Internet research

    2023  Volume 25, Page(s) e47629

    Abstract: Understanding the impact of caregiving responsibilities on women in medicine is crucial for ensuring a healthy and intact workforce, as caregiving responsibilities have the potential to affect the careers of women in health care along the entire pipeline, ...

    Abstract Understanding the impact of caregiving responsibilities on women in medicine is crucial for ensuring a healthy and intact workforce, as caregiving responsibilities have the potential to affect the careers of women in health care along the entire pipeline, from students and trainees to physicians, physician-scientists, and biomedical researchers.
    MeSH term(s) Female ; Humans ; Medicine ; Fatigue ; Health Status ; Physicians ; Research Personnel
    Language English
    Publishing date 2023-06-14
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2028830-X
    ISSN 1438-8871 ; 1438-8871
    ISSN (online) 1438-8871
    ISSN 1438-8871
    DOI 10.2196/47629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Burnout During the COVID-19 Pandemic: A Report on Pediatric Residents.

    Zuniga, Linessa M / Schuh, Abigail / Schwartz, Alan / Seo-Mayer, Patricia / Cramton, Rachel / Sieplinga, Kira / Kaushik, Ruchi / Nassetta, Lauren / Homme, Jason H / Babal, Jessica / Mahan, John D / Batra, Maneesh

    Academic pediatrics

    2023  Volume 23, Issue 8, Page(s) 1620–1627

    Abstract: Background and objective: The Pediatric Resident Burnout and Resilience Consortium (PRB-RSC) has described the epidemiology of burnout in pediatric residents since 2016. We hypothesized burnout rates during the pandemic would increase. We explored ... ...

    Abstract Background and objective: The Pediatric Resident Burnout and Resilience Consortium (PRB-RSC) has described the epidemiology of burnout in pediatric residents since 2016. We hypothesized burnout rates during the pandemic would increase. We explored resident burnout during the COVID-19 pandemic and its relationship to resident perception of workload, training, personal life, and local COVID burden.
    Methods: Since 2016, PRB-RSC has sent an annual, confidential survey to over 30 pediatric and medicine-pediatrics residencies. In 2020 and 2021, seven questions were added to explore the relationship of COVID-19 and perceptions of workload, training, and personal life.
    Results: In 2019, 46 programs participated, 22 in 2020, and 45 in 2021. Response rates in 2020 (n = 1055, 68%) and 2021(n = 1702, 55%) were similar to those of previous years (P = .09). Burnout rates in 2020 were significantly lower than in 2019 (54% vs 66%, P < .001) but returned to pre-COVID levels in 2021 (65%, P = .90). In combined 2020-2021 data, higher rates of burnout were associated with reported increased workload (Adjusted Odds Ratio (AOR) 1.38, 95% CI 1.19-1.6) and concerns regarding the effect of COVID on training (AOR 1.35, 95% CI 1.2-1.53). Program-level county COVID burden in combined 2020-2021 data was not associated with burnout in this model (AOR=1.03, 95% CI 0.70-1.52).
    Conclusions: Burnout rates within reporting programs decreased significantly in 2020 and returned to prepandemic levels in 2021. Increased burnout was associated with perceived increases in workload and concerns regarding effect of the pandemic on training. Given these findings, programs should consider further investigation into workload and training uncertainty on burnout.
    MeSH term(s) Humans ; Child ; COVID-19/epidemiology ; Pandemics ; Burnout, Professional/epidemiology ; Workload ; Surveys and Questionnaires ; Internship and Residency
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2483385-X
    ISSN 1876-2867 ; 1876-2859
    ISSN (online) 1876-2867
    ISSN 1876-2859
    DOI 10.1016/j.acap.2023.05.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Drip System for Admissions to Resident Teams: Impact on Workload and Education.

    Berger, Stephanie / Nassetta, Lauren B / Hofto, Meghan E / Scalici, Paul / Pass, Robert F

    Southern medical journal

    2020  Volume 113, Issue 12, Page(s) 635–639

    Abstract: Objectives: Assigning patients to a call team every fourth day (bolus system) caused the maldistribution of patients among resident teams and required additional faculty effort for overflow patient care. We changed to a continuous daily rotation (drip ... ...

    Abstract Objectives: Assigning patients to a call team every fourth day (bolus system) caused the maldistribution of patients among resident teams and required additional faculty effort for overflow patient care. We changed to a continuous daily rotation (drip system) and examined the effect on clinical workload among resident teams, resident education, and faculty utilization.
    Methods: This is a retrospective study based on the daily records of 7 am team census, the attending physician schedules for a pediatric hospital medicine service with 5 teams, and the measures of resident education, including noon conference attendance, scores on in-service examinations, and duty hour violations. Data from the bolus system (May 2014-June 2015) were compared with the drip system (May 2016-June 2017).
    Results: Data from 348 bolus days and 338 drip days were analyzed. There was a decrease in interteam variation from 6.2 to 3.9 patients (
    Conclusions: Changing from a bolus to a drip model for admissions to inpatient teams resulted in a more even distribution of the workload and a more efficient use of physician resources without negatively affecting resident education.
    MeSH term(s) Academic Medical Centers/organization & administration ; Academic Medical Centers/statistics & numerical data ; Humans ; Internship and Residency/organization & administration ; Internship and Residency/statistics & numerical data ; Patient Admission ; Patient Care Team/organization & administration ; Patient Care Team/statistics & numerical data ; Retrospective Studies ; Workload/statistics & numerical data
    Language English
    Publishing date 2020-11-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 185329-6
    ISSN 1541-8243 ; 0038-4348
    ISSN (online) 1541-8243
    ISSN 0038-4348
    DOI 10.14423/SMJ.0000000000001183
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Quality Improvement Project to Improve Screening for Tobacco Use in Adolescent Inpatients at a Children's Hospital.

    Wagner, Lauren A / Molina, Adolfo L / Grizzle, Karisa / Hofto, Meghan E / Nassetta, Lauren B / Orr, Mary M / Samuy, Nichole / Schmit, Erinn O / Smola, Cassi / Harrington, Kathleen F / Walley, Susan C

    Children (Basel, Switzerland)

    2019  Volume 6, Issue 3

    Abstract: Tobacco use begins in adolescence for the majority of smokers. The purpose of this study was to increase screening and reporting of tobacco use in hospitalized adolescents at a tertiary care children's hospital. We completed a nursing focus group to ... ...

    Abstract Tobacco use begins in adolescence for the majority of smokers. The purpose of this study was to increase screening and reporting of tobacco use in hospitalized adolescents at a tertiary care children's hospital. We completed a nursing focus group to understand challenges and completed four iterative Plan-Do-Study-Act cycles, which included: (1) in-person nursing education regarding tobacco use screening, (2) addition of an e-cigarette-specific screening question, (3) the creation and dissemination of an educational video for nursing, and (4) adding the video as a mandatory component of nursing orientation. Run charts of the percentage of patients screened who reported tobacco use were created. Absolute counts of tobacco products used were also captured. From January 2016 to September 2018, 12,999 patients ≥13 years of age were admitted to the hospital. At baseline, 90.1% of patients were screened and 4.8% reported tobacco use. While the absolute number of adolescents reporting e-cigarette use increased from zero patients per month at baseline to five, the percentage of patients screened and reporting tobacco use was unchanged; the majority of e-cigarette users reported use of other tobacco products. This study demonstrates that adding e-cigarettes to screening increases reporting and suggests systems level changes are needed to improve tobacco use reporting.
    Language English
    Publishing date 2019-02-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children6030037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Treatment of congenital cytomegalovirus infection: implications for future therapeutic strategies.

    Nassetta, Lauren / Kimberlin, David / Whitley, Richard

    The Journal of antimicrobial chemotherapy

    2009  Volume 63, Issue 5, Page(s) 862–867

    Abstract: Cytomegalovirus (CMV) infection is the most common cause of congenital infection in the developed world, occurring in approximately 1% of all liveborns. Symptomatic disease occurs in 10% of all congenitally infected infants, resulting in a spectrum of ... ...

    Abstract Cytomegalovirus (CMV) infection is the most common cause of congenital infection in the developed world, occurring in approximately 1% of all liveborns. Symptomatic disease occurs in 10% of all congenitally infected infants, resulting in a spectrum of clinical manifestations that include microcephaly, chorioretinitis, hepatosplenomegaly and sensorineural hearing loss, among others. Even those children who are asymptomatic at birth have a risk of hearing loss, with approximately 8% experiencing this sequela. Overall, congenital CMV infection accounts for one-third of all cases of sensorineural hearing loss. The economic burden of disease exceeds $2 billion annually in the USA. Therefore, this infection has been the target for antiviral therapy. Studies performed by the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group (CASG) have evaluated ganciclovir for the treatment of symptomatic congenital CMV infection with central nervous system involvement. In a randomized, controlled clinical trial of ganciclovir treatment (6 mg/kg iv every 12 h for 6 weeks) brainstem-evoked responses were utilized as the primary endpoint and demonstrated stabilization of hearing both at 6 months and >1 year. Treatment was associated with neutropenia in over 60% of treated patients. Since ganciclovir must be given intravenously, studies with its prodrug, valganciclovir, have been performed to assess pharmacokinetics and pharmacodynamics. Currently, a clinical trial of 6 weeks versus 6 months of valganciclovir is being performed by the CASG. Notably, only intravenous ganciclovir and orally administered valganciclovir have been used to treat congenital CMV infection. Hopefully, other drugs such as maribavir will be available for evaluation in this population.
    MeSH term(s) Antiviral Agents/adverse effects ; Antiviral Agents/therapeutic use ; Clinical Trials as Topic ; Cytomegalovirus Infections/complications ; Cytomegalovirus Infections/congenital ; Cytomegalovirus Infections/drug therapy ; Ganciclovir/analogs & derivatives ; Ganciclovir/therapeutic use ; Hearing Loss, Central/prevention & control ; Humans ; Infant ; Neutropenia/chemically induced ; United States ; Valganciclovir
    Chemical Substances Antiviral Agents ; Valganciclovir (GCU97FKN3R) ; Ganciclovir (P9G3CKZ4P5)
    Language English
    Publishing date 2009-03-14
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkp083
    Database MEDical Literature Analysis and Retrieval System OnLINE

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