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Article: Innovative use of a flipped-classroom approach to teach fundamental nursing skills.

Wilson, Kimberly E / Hobbs, Jill R

Teaching and learning in nursing : official journal of the National Organization for Assciate Degree Nursing

2022 Volume 18, Issue 1, Page(s) 144–147

Abstract: Prelicensure nursing students are required to master fundamental nursing skills. The COVID-19 pandemic created challenges in maintaining excellence while teaching skill acquisition. The purpose of this study was to evaluate skill validation scores and ... ...

Abstract	Prelicensure nursing students are required to master fundamental nursing skills. The COVID-19 pandemic created challenges in maintaining excellence while teaching skill acquisition. The purpose of this study was to evaluate skill validation scores and student satisfaction and self-confidence using a flipped classroom approach and a low-fidelity simulation model to innovatively teach skill acquisition. Researchers used a quasi-experimental method to compare skill validation scores of a control group and intervention group using independent samples t-test. Researchers also evaluated whether prelicensure nursing students had satisfaction and self-confidence with this teaching strategy. Findings suggested that skills validations scores were no different using a flipped-classroom approach than in-person instruction. Prelicensure nursing students were satisfied and self-confident following the implementation of this teaching strategy. This teaching strategy has the potential to decrease in-person clinical practice time, provide alternative opportunities for clinical make-up and remediation, and decrease cost.
Language	English
Publishing date	2022-09-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2424501-X
ISSN	1557-3087 ; 1557-2013
ISSN (online)	1557-3087
ISSN	1557-2013
DOI	10.1016/j.teln.2022.08.002
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Article ; Online: Stellate Ganglion Blockade for Corticobasal Syndrome Pain: A Case Report and Potential New Discovery.

Hobbs, Leith / Fuller, Redgy / Cameron-Smith, Erin

Movement disorders clinical practice

2023 Volume 10, Issue 5, Page(s) 848–849

Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Journal Article
ISSN	2330-1619
ISSN (online)	2330-1619
DOI	10.1002/mdc3.13691
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Article: Effects of incubation temperature on the upper thermal tolerance of the imperiled longfin smelt (

Yanagitsuru, Yuzo R / Mauduit, Florian / Lundquist, Alexis J / Lewis, Levi S / Hobbs, James A / Hung, Tien-Chieh / Connon, Richard E / Fangue, Nann A

Conservation physiology

2024 Volume 12, Issue 1, Page(s) coae004

Abstract: Upper thermal limits in many fish species are limited, in part, by the heart's ability to meet increased oxygen demand during high temperatures. Cardiac plasticity induced by developmental temperatures can therefore influence thermal tolerance. Here, we ... ...

Abstract	Upper thermal limits in many fish species are limited, in part, by the heart's ability to meet increased oxygen demand during high temperatures. Cardiac plasticity induced by developmental temperatures can therefore influence thermal tolerance. Here, we determined how incubation temperatures during the embryonic stage influence cardiac performance across temperatures during the sensitive larval stage of the imperiled longfin smelt. We transposed a cardiac assay for larger fish to newly hatched larvae that were incubated at 9°C, 12°C or 15°C. We measured heart rate over increases in temperature to identify the Arrhenius breakpoint temperature (T
Language	English
Publishing date	2024-02-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2721508-8
ISSN	2051-1434
ISSN	2051-1434
DOI	10.1093/conphys/coae004
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Article ; Online: Propofol-induced interference with activated partial thromboplastin time-based monitoring of therapeutic heparin anticoagulation.

Negaard, Briana J / Hobbs, Ryan / Frye, Jared R / Merrill, Anna E

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

2022 Volume 80, Issue 7, Page(s) 445–451

Abstract: Purpose: The activated partial thromboplastin time (aPTT) is a coagulation assay commonly utilized for monitoring therapeutic heparin anticoagulation. aPTT methods based on optical detection are vulnerable to spectral interference from hemolysis, ... ...

Abstract	Purpose: The activated partial thromboplastin time (aPTT) is a coagulation assay commonly utilized for monitoring therapeutic heparin anticoagulation. aPTT methods based on optical detection are vulnerable to spectral interference from hemolysis, icterus, lipemia, and other substances. Intravenous lipid emulsions of primarily 20% have been shown to interfere with multiple clinical laboratory assays, including those measuring aPTT by optical methods, but there is limited data on propofol's effect. The primary objective of this study was to determine the rate of interference of propofol with aPTT measurements in patients receiving both propofol and intravenous heparin. Methods: A retrospective observational cohort study of intensive care unit patients who received concomitant propofol and heparin infusions (N = 38 patients) and whose heparin therapy was monitored by aPTT (N = 531 aPTTs) was conducted. Review of the electronic medical record was completed to obtain relevant clinical and laboratory data, while the laboratory information system was queried for analytical interference with the aPTT assay. Results: A total of 109 aPTTs (21%) spanning 21 patients (55%) had documented aPTT interference. All 21 patients had at least one aPTT requiring ultracentrifugation prior to reporting, and 12 aPTTs from 4 patients were unreportable due to interference. Patients with and without aPTT interference received similar doses of propofol. None of the cases of aPTT interference were caused by hemolysis or hyperbilirubinemia. Conclusion: A potential medication-assay interaction was observed in approximately half of patients who received concomitant propofol and heparin infusions and had aPTT measured for anticoagulation management. Sample ultracentrifugation removes the optical interference in most cases but significantly prolongs aPTT reporting and delays appropriate adjustments to heparin dosing.
MeSH term(s)	Humans ; Heparin ; Partial Thromboplastin Time ; Propofol/adverse effects ; Retrospective Studies ; Hemolysis ; Anticoagulants
Chemical Substances	Heparin (9005-49-6) ; Propofol (YI7VU623SF) ; Anticoagulants
Language	English
Publishing date	2022-11-12
Publishing country	England
Document type	Observational Study ; Journal Article
ZDB-ID	1224627-x
ISSN	1535-2900 ; 1079-2082
ISSN (online)	1535-2900
ISSN	1079-2082
DOI	10.1093/ajhp/zxac337
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Article ; Online: Triclosan and Methyl Triclosan in Prey Fish in a Wastewater-Influenced Estuary.

Lin, Diana / Hamilton, Coreen / Hobbs, James / Miller, Ezra / Sutton, Rebecca

Environmental toxicology and chemistry

2023 Volume 42, Issue 3, Page(s) 620–627

Abstract: While the antimicrobial ingredient triclosan has been widely monitored in the environment, much less is known about the occurrence and toxicity of its major transformation product, methyl triclosan. An improved method was developed and validated to ... ...

Abstract	While the antimicrobial ingredient triclosan has been widely monitored in the environment, much less is known about the occurrence and toxicity of its major transformation product, methyl triclosan. An improved method was developed and validated to effectively extract and quantify both contaminants in fish tissue and used to characterize concentrations in small prey fish in areas of San Francisco Bay where exposure to triclosan via municipal wastewater discharges was expected to be highest. Concentrations of triclosan (0.44-57 ng/g wet wt, median 1.9 ng/g wet wt) and methyl triclosan (1.1-200 ng/g wet wt, median 36 ng/g wet wt) in fish tissue decreased linearly with concentrations of nitrate in site water, used as indicators of wastewater influence. The total concentrations of triclosan and methyl triclosan measured in prey fish were below available toxicity thresholds for triclosan, but there are few ecotoxicological studies to evaluate impacts of methyl triclosan. Methyl triclosan represented up to 96% of the total concentrations observed. These results emphasize the importance of monitoring contaminant transformation products, which can be present at higher levels than the parent compound. Environ Toxicol Chem 2023;42:620-627. © 2023 SETAC.
MeSH term(s)	Animals ; Triclosan/toxicity ; Wastewater ; Estuaries ; Environmental Monitoring/methods ; Water Pollutants, Chemical/analysis ; Fishes
Chemical Substances	methyl triclosan (5174UR1DP5) ; Triclosan (4NM5039Y5X) ; Wastewater ; Water Pollutants, Chemical
Language	English
Publishing date	2023-02-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	46234-2
ISSN	1552-8618 ; 0730-7268
ISSN (online)	1552-8618
ISSN	0730-7268
DOI	10.1002/etc.5557
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Article ; Online: Consumer knowledge of mental health conditions, awareness of mental health support services, and perception of community pharmacists' role in mental health promotion.

Singleton, Judith / Stevens, Julie E / Truong, Raymond / McCulloch, Adam / Ara, Elay / Cooper, Maria B / Hobbs, Britany / Hotham, Elizabeth / Suppiah, Vijayaprakash

The International journal of pharmacy practice

2023 Volume 32, Issue 2, Page(s) 170–179

Abstract: ... of participants were aware of Mental Health Week and the R U OK? Campaign, respectively. Whilst 12.4 ...

Abstract	Objective: To explore community pharmacy consumers' knowledge and attitudes of mental illness, support services, and community pharmacists' role in supporting people living with mental illness (PLMI). Methods: This survey was conducted in 15 community pharmacies between June and September 2019. Participants were aged 18 years or older without prior or ongoing history of mental illness and/or with close family members with mental illness. Open-ended responses to the anonymous questionnaire were analysed using content analysis. Key findings: Majority of the 380 participants were female (57.4%) with a mean age 52.9 years and 33.7% having completed university. Most (70.3%) believed that people with mental illness had a negative image due to poor health literacy providing possible solutions of 'awareness campaigns', 'education and training', and 'increased government funding for mental health (MH) support services'. Only 33.7% and 63.7% of participants were aware of Mental Health Week and the R U OK? Campaign, respectively. Whilst 12.4% of participants had participated in MH campaigns, only 3.4% were aware of community pharmacists-led MH educational activities. There were significant differences between adults (<65 years) and older adults (≥65 years old) with the latter reporting a more negative image for mental illness (P < 0.05) and having less exposure and engagement with MH resources (P < 0.001) and campaigns (P < 0.01). Conclusion: Despite awareness, participants reported low engagement with MH campaigns. Additionally, older adults had lower MH literacy and exposure to resources and campaigns. This study highlighted that the community lacked awareness of what pharmacists can offer to support PLMIs.
MeSH term(s)	Humans ; Male ; Female ; Aged ; Middle Aged ; Pharmacists/psychology ; Mental Health ; Community Pharmacy Services ; Mental Disorders/therapy ; Health Promotion ; Attitude of Health Personnel ; Perception ; Professional Role
Language	English
Publishing date	2023-12-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1087040-4
ISSN	2042-7174 ; 0961-7671
ISSN (online)	2042-7174
ISSN	0961-7671
DOI	10.1093/ijpp/riad091
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Article ; Online: Gut microbiome health and dysbiosis: A clinical primer.

Bidell, Monique R / Hobbs, Athena L V / Lodise, Thomas P

Pharmacotherapy

2022 Volume 42, Issue 11, Page(s) 849–857

Abstract: ... as well as the consequences of a disrupted microbiome (i.e., dysbiosis). Management strategies to restore ...

Abstract	The gut microbiome has been referred to as the "forgotten organ." Although much about the gut microbiome remains incompletely understood, data on its clinical importance is emerging at rapid speed. Many practicing clinicians may be unaware of the essential role that the microbiome plays in both health and disease. This review aims to improve clinical understanding of the gut microbiome by discussing key terminology and foundational concepts. The role of a healthy microbiome in normal host function is described, as well as the consequences of a disrupted microbiome (i.e., dysbiosis). Management strategies to restore the gut microbiome from a disrupted to a healthy state are also briefly discussed. Lastly, we review emerging areas for therapeutic potential and opportunity to bring determinants of microbiome health from the bench to bedside.
MeSH term(s)	Humans ; Dysbiosis ; Gastrointestinal Microbiome
Language	English
Publishing date	2022-10-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	603158-4
ISSN	1875-9114 ; 0277-0008
ISSN (online)	1875-9114
ISSN	0277-0008
DOI	10.1002/phar.2731
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Article: Bioturbation by a reintroduced digging mammal reduces fuel loads in an urban reserve.

Ryan, C M / Hobbs, R J / Valentine, L E

Ecological applications : a publication of the Ecological Society of America

2020 Volume 30, Issue 2, Page(s) e02018

Abstract: Digging animals may alter many characteristics of their environment as they disrupt and modify the ground's surface by creating foraging pits or burrows. Extensive disturbance to the soil and litter layer changes litter distribution and availability, ... ...

Abstract	Digging animals may alter many characteristics of their environment as they disrupt and modify the ground's surface by creating foraging pits or burrows. Extensive disturbance to the soil and litter layer changes litter distribution and availability, potentially altering fuel loads. In many landscapes, including peri-urban areas, fire management to reduce fuel loads is complex and challenging. The reintroduction of previously common digging animals, many of which are now threatened, may have the added benefit of reducing fuel loads. We experimentally examined how the reintroduction of a marsupial bandicoot, quenda (Isoodon fusciventer), altered surface fuel loads in an urban bush reserve in Perth, Western Australia. Foraging activities of quenda (where they dig for subterranean food) were substantial throughout the reserve, creating a visibly patchy distribution in surface litter. Further, in open plots where quenda had access, compared to fenced plots where quenda were excluded, quenda foraging significantly reduced litter cover and litter depth. Similarly, estimated surface fuel loads were nearly halved in open plots where quenda foraged compared to fenced plots where quenda were absent (3.6 cf. 6.4 Mg/ha). Fire behavior modeling, using the estimated surface fuel loads, indicated the predicted rate of spread of fire were significantly lower for open plots where quenda foraged compared to fenced plots under both low (29.2 cf. 51.4 m/h; total fuels) and high (74.3 cf. 130.4 m/h; total fuels) fire conditions. Although many environments require fire, including the bushland where this study occurred, fire management can be a considerable challenge in many landscapes, including urban bushland reserves, which are usually small and close to human infrastructure. The reintroduction of previously common digging species may have potential value as a complimentary tool for reducing fuel loads, and potentially, fire risk.
MeSH term(s)	Animals ; Ecosystem ; Fires ; Humans ; Marsupialia ; Plants ; Soil ; Western Australia
Chemical Substances	Soil
Language	English
Publishing date	2020-01-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1074505-1
ISSN	1939-5582 ; 1051-0761
ISSN (online)	1939-5582
ISSN	1051-0761
DOI	10.1002/eap.2018
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Article ; Online: Strengthening effectiveness evaluations through gender integration to improve programs for women, newborn, child, and adolescent health.

Morgan, Rosemary / Garrison-Desany, Henri / Hobbs, Amy J / Wilson, Emily

Global health action

2022 Volume 15, Issue sup1, Page(s) 2006420

Abstract: Over the past decade, there has been substantial progress towards integrating our understanding of social determinants of reproductive, maternal, newborn, child, and adolescent health (RMNCAH) into health planning and programs. For these programs, gender ...

Abstract	Over the past decade, there has been substantial progress towards integrating our understanding of social determinants of reproductive, maternal, newborn, child, and adolescent health (RMNCAH) into health planning and programs. For these programs, gender inequity remains one of the most harmful factors for women's access to healthcare. Designing RMNCAH programs to be gender-responsive through active engagement with and overcoming of gender-related barriers remains paramount to increasing women's access to and use of health programs. However, the integration of gender within RMNCAH programs and their evaluation is often non-existent or is limited in scope. Building on a prior framework for comprehensive gender analysis in RMNCAH, we discuss key steps used to incorporate a gender lens and analytical approach in the Real Accountability: Data Analysis for Results (RADAR) evaluation framework. In order to effectively address these key areas, gender must be integrated into all stages of the evaluation, including tool development and programmatic activities that are associated with each question. Our paper includes practical activities and tools that evaluators may use to integrate gender into their evaluation tools.
MeSH term(s)	Adolescent ; Adolescent Health ; Child ; Family ; Female ; Health Planning ; Humans ; Infant, Newborn ; Interpersonal Relations ; United States
Language	English
Publishing date	2022-09-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2540569-X
ISSN	1654-9880 ; 1654-9880
ISSN (online)	1654-9880
ISSN	1654-9880
DOI	10.1080/16549716.2021.2006420
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Article ; Online: Comparing Risk Assessment Between Payers and Providers: Inconsistent Agreement in Medical Comorbidity Records for Patients Undergoing Total Joint Arthroplasty.

Hobbs, John R / Magnuson, Justin A / Woelber, Erik / Sarangdhar, Kalpak / Courtney, P Maxwell / Krueger, Chad A

The Journal of arthroplasty

2023 Volume 38, Issue 10, Page(s) 2105–2113

Abstract: Background: The proper risk adjustment for total hip arthroplasty (THA) and total knee arthroplasty (TKA) relies on an accurate assessment of comorbidity profiles by both the payer and the institution. The purpose of this study was to determine how ... ...

Abstract	Background: The proper risk adjustment for total hip arthroplasty (THA) and total knee arthroplasty (TKA) relies on an accurate assessment of comorbidity profiles by both the payer and the institution. The purpose of this study was to determine how strongly comorbidities tracked by our institution agreed with the same comorbidities reported by payers in patients undergoing THA and TKA. Methods: All patients of a single payer undergoing primary THA and TKA at a single institution between January 5, 2021 and March 31, 2022 were included (n = 876). There were 8 commonly collected medical comorbidities obtained from institutional medical records and matched with patient records reported by the payer. Fleiss Kappa tests were used to determine agreement of payer data with institutional records. There were 4 medical risk calculations collected from our institutional records and compared with an insurance member risk score reported by the payer. Results: Comorbidities reported by the institution differed significantly from those reported by payers, with Kappa varying between 0.139 and 0.791 for THA, and 0.062 and 0.768 for TKA. Diabetes was the only condition to demonstrate strong agreement for both procedures (THA; k = 0.791, TKA; k = 0.768). The insurance member risk score demonstrates the closest association with total cost and surplus for THA regardless of insurance type and for TKA procedures paid for with private commercial insurance. Conclusion: There is a lack of agreement between medical comorbidities within payer and institutional records for both THA and TKA. These differences may put institutions at a disadvantage within value-based care models and when optimizing patients perioperatively.
MeSH term(s)	Humans ; Arthroplasty, Replacement, Knee ; Risk Assessment ; Arthroplasty, Replacement, Hip ; Comorbidity ; Risk Factors
Language	English
Publishing date	2023-05-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	632770-9
ISSN	1532-8406 ; 0883-5403
ISSN (online)	1532-8406
ISSN	0883-5403
DOI	10.1016/j.arth.2023.05.011
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