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  1. Article: Im Gespräch: Gerd Hasenfuß, Kardiologe und Präsident des 122. Internistenkongresses, zum demografischen Wandel

    Siegmund-Schultze, Nicola / Hasenfuß, Gerd

    Deutsches Ärzteblatt : Ausgabe A, Praxis-Ausgabe : niedergelassene Ärzte

    2016  Volume 113, Issue 14, Page(s) 658

    Language German
    Document type Article
    ZDB-ID 1453475-7
    ISSN 0012-1207
    Database Current Contents Medicine

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  2. Article: Resümee von Professor Dr. Gerd Hasenfuß, Kongresspräsident der DGIM 2016 und Vorsitzender der DGIM 2015/2016

    Hasenfuß, Gerd

    DMW - Deutsche Medizinische Wochenschrift

    2016  Volume 141, Issue 11, Page(s) 819–820

    Language German
    Publishing date 2016-06-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0042-108891
    Database Thieme publisher's database

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  3. Book ; Online: Digitales Gesundheitswesen: Chancen, Nutzen, Risiken

    Albrecht, Urs-Vito / Hasenfuß, Gerd / Rebscher, Herbert / Staeck, Florian / Winkler, Eva C.

    (Diskurse / Frankfurter Forum ; Heft 16 (Oktober 2017))

    2017  

    Author's details Autoren: PD Dr. Urs-Vito Albrecht, Prof. Dr. Gerd Hasenfuß, Prof. Dr. h.c. Herbert Rebscher, Dr. Florian Staeck, Prof. Dr. Dr. Eva Winkler
    Series title Diskurse / Frankfurter Forum ; Heft 16 (Oktober 2017)
    Diskurse
    Collection Diskurse
    Language German
    Size 1 Online-Ressource (42 Seiten), Illustrationen, Diagramme
    Publisher Frankfurter Forum für gesellschafts- und gesundheitspolitische Grundsatzfragen e.V
    Publishing place Hanau
    Publishing country Germany
    Document type Book ; Online
    Note Open Access
    HBZ-ID HT020016233
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Is myosin activation a new treatment for heart failure?

    Hasenfuss, Gerd

    European journal of heart failure

    2020  Volume 22, Issue 9, Page(s) 1659–1661

    MeSH term(s) Cardiac Myosins ; Cardiotonic Agents/therapeutic use ; Heart Failure/drug therapy ; Humans ; Myosins
    Chemical Substances Cardiotonic Agents ; Cardiac Myosins (EC 3.6.1.-) ; Myosins (EC 3.6.4.1)
    Language English
    Publishing date 2020-09-01
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 1483672-5
    ISSN 1879-0844 ; 1388-9842
    ISSN (online) 1879-0844
    ISSN 1388-9842
    DOI 10.1002/ejhf.1983
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Geschlechtsspezifische Unterschiede in der Kardiologie.

    Sandek, Anja / Hasenfuß, Gerd

    Innere Medizin (Heidelberg, Germany)

    2022  Volume 64, Issue 8, Page(s) 727–735

    Abstract: Background: Evidence in cardiovascular patient care is currently skewed to the disadvantage of women. This article provides a summary of the current state of knowledge on gender differences with a special focus on the epidemiology, pathophysiology, risk ...

    Title translation Gender-specific differences in cardiology.
    Abstract Background: Evidence in cardiovascular patient care is currently skewed to the disadvantage of women. This article provides a summary of the current state of knowledge on gender differences with a special focus on the epidemiology, pathophysiology, risk factors and treatment of the most frequent cardiovascular diseases.
    Material and methods: Evaluation and discussion of background research and expert recommendations.
    Results: The necessity for a gender-specific analysis of results is a relatively recent development in clinical trials. There is increasing evidence for pathogenic mechanisms specific for women as well as pharmacodynamic and pharmacokinetic differences between women and men. Women are currently less likely to receive treatment for cardiac diseases according to medical guidelines than men.
    Conclusion: For improvement of the treatment options and effective disease prevention, it is pivotal to investigate pathogenetic mechanisms specific to women.
    MeSH term(s) Humans ; Male ; Female ; Sex Characteristics ; Heart Diseases/epidemiology ; Risk Factors
    Language German
    Publishing date 2022-12-01
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ISSN 2731-7099
    ISSN (online) 2731-7099
    DOI 10.1007/s00108-022-01437-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Secondary prevention of cardiovascular diseases: current state of the art.

    Hasenfuß, Gerd

    Kardiologia polska

    2018  Volume 76, Issue 12, Page(s) 1671–1679

    Abstract: Prevention strategies for cardiac events depend of the risk for such an event. A very high risk is defined as a risk > 10% over 10 years. For example, a patient with known coronary artery disease has such a very high risk of death. However, a patient ... ...

    Abstract Prevention strategies for cardiac events depend of the risk for such an event. A very high risk is defined as a risk > 10% over 10 years. For example, a patient with known coronary artery disease has such a very high risk of death. However, a patient with diabetes and severe hypertension without known coronary artery disease carries the same risk. Here, secondary preven-tion and primary prevention overlap. Prevention guidelines include a number of general recommendations, such as changes in behaviour, nutrition, body weight, and physical activity as well as smoking intervention strategies. Drug treatment-based prevention strategies address diabetes mellitus, hypercholesterolaemia, platelet aggregation, and arterial hypertension. Follow-ing hospitalisation for heart failure or acute coronary syndrome, participation in a centre-based or home-based rehabilitation programme is recommended. There are a number of new treatment options with a promising potential to reduce the rate of events in patients with cardiovascular diseases and in patients with cardiovascular risk factors. Very recent treatment strategies include the PCSK9 inhibitors for hypercholesterolaemia and the SGLT2 inhibitors for reduction of cardiovascular events in patients with diabetes mellitus and increased cardiovascular risk.
    MeSH term(s) Acute Coronary Syndrome/complications ; Acute Coronary Syndrome/prevention & control ; Cardiovascular Diseases/complications ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/prevention & control ; Humans ; Hypercholesterolemia/complications ; Hypercholesterolemia/prevention & control ; Hypertension/complications ; Hypertension/prevention & control ; Practice Guidelines as Topic ; Risk Factors ; Secondary Prevention/standards ; Stroke/complications ; Stroke/prevention & control
    Language English
    Publishing date 2018-10-19
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 411492-9
    ISSN 1897-4279 ; 0022-9032
    ISSN (online) 1897-4279
    ISSN 0022-9032
    DOI 10.5603/KP.a2018.0198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book: Diagnostik und Therapie der diastolischen Herzinsuffizienz

    Hasenfuß, Gerd / Wachter, Rolf

    22 Tabellen

    2008  

    Author's details G. Hasenfuß ; R. Wachter
    Keywords Herzinsuffizienz
    Subject Herzmuskelinsuffizienz ; Herzschwäche ; Heart failure ; Cardiac failure ; Myokardinsuffizienz
    Language German
    Size VIII, 80 S. : Ill., graph. Darst., 7190 mm x 127 mm, 120 gr.
    Publisher Thieme
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT015728338
    ISBN 978-3-13-147431-5 ; 3-13-147431-9
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2008 A 6539 order for loan Magazin

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  8. Article ; Online: Programm 2020 der Deutschen Gesellschaft für Innere Medizin.

    Hasenfuß, Gerd

    Deutsche medizinische Wochenschrift (1946)

    2017  Volume 142, Issue 3, Page(s) 145–146

    Title translation Program 2020 of the German Society of Internal Medicine.
    Language German
    Publishing date 2017-02
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0043-100120
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  9. Article ; Online: Digitale Medizin--die Herausforderung.

    Hasenfuß, Gerd

    Deutsche medizinische Wochenschrift (1946)

    2016  Volume 141, Issue 7, Page(s) 451

    Title translation Digital medicine--a new challenge.
    MeSH term(s) Delivery of Health Care, Integrated/trends ; Genomics ; Humans ; Medical Informatics ; Mobile Applications ; Telemedicine
    Language German
    Publishing date 2016-04
    Publishing country Germany
    Document type Editorial
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0042-104300
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  10. Article ; Online: Noninvasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM.

    Rapöhn, Marcel / Cyganek, Lukas / Voigt, Niels / Hasenfuß, Gerd / Lehnart, Stephan E / Wegener, Jörg W

    American journal of physiology. Heart and circulatory physiology

    2024  Volume 326, Issue 3, Page(s) H599–H611

    Abstract: Patient-derived induced pluripotent stem cells (iPSCs) can be differentiated into atrial and ventricular cardiomyocytes to allow for personalized drug screening. A hallmark of differentiation is the manifestation of spontaneous beating in a two- ... ...

    Abstract Patient-derived induced pluripotent stem cells (iPSCs) can be differentiated into atrial and ventricular cardiomyocytes to allow for personalized drug screening. A hallmark of differentiation is the manifestation of spontaneous beating in a two-dimensional (2-D) cell culture. However, an outstanding observation is the high variability in this maturation process. We valued that contractile parameters change during differentiation serving as an indicator of maturation. Consequently, we recorded noninvasively spontaneous motion activity during the differentiation of male iPSC toward iPSC cardiomyocytes (iPSC-CMs) to further analyze similar maturated iPSC-CMs. Surprisingly, our results show that identical differentiations into ventricular iPSC-CMs are variable with respect to contractile parameters resulting in two distinct subpopulations of ventricular-like cells. In contrast, differentiation into atrial iPSC-CMs resulted in only one phenotype. We propose that the noninvasive and cost-effective recording of contractile activity during maturation using a smartphone device may help to reduce the variability in results frequently reported in studies on ventricular iPSC-CMs.
    MeSH term(s) Humans ; Male ; Induced Pluripotent Stem Cells ; Myocytes, Cardiac ; Cell Differentiation ; Phenotype ; Heart Ventricles
    Language English
    Publishing date 2024-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603838-4
    ISSN 1522-1539 ; 0363-6135
    ISSN (online) 1522-1539
    ISSN 0363-6135
    DOI 10.1152/ajpheart.00527.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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