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  1. Book ; Online ; E-Book: Clinical cardiac electrophysiology

    Katritsis, Demosthenes G. / Morady, Fred

    a practical guide

    2022  

    Abstract: Offering a clear and consistent framework for recognition, diagnosis, and treatment of a wide range of cardiac arrhythmia disturbances, Clinical Cardiac Electrophysiology: A Practical Guide covers the fundamental analytical skills needed in this ... ...

    Author's details Demosthenes G. Katritsis, Fred Morady
    Abstract Offering a clear and consistent framework for recognition, diagnosis, and treatment of a wide range of cardiac arrhythmia disturbances, Clinical Cardiac Electrophysiology: A Practical Guide covers the fundamental analytical skills needed in this challenging area. This portable, highly accessible handbook focuses on the basics of clinical electrophysiology-- how and when to perform an electrophysiology study as well as principles of ablation and other invasive therapies--all in a succinct and modern format
    Keywords Electrocardiography ; Heart / Electric properties ; Arrhythmias, Cardiac / diagnosis ; Electrophysiology / methods ; Arrhythmias, Cardiac / therapy ; Heart Conduction System / physiopathology ; Heart ; Electric properties
    Language English
    Size 1 Online-Ressource (XII, 379 Seiten), Illustrationen, Diagramme
    Publisher Elsevier
    Publishing place Philadelphia, PA
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021593679
    ISBN 978-0-323-79339-1 ; 9780323793384 ; 0-323-79339-8 ; 032379338X
    DOI 10.1016/C2019-0-05527-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Diagnosis and cure of supraventricular tachycardia.

    Morady, Fred

    Heart rhythm

    2021  Volume 18, Issue 4, Page(s) 651–652

    MeSH term(s) Catheter Ablation/methods ; Electrocardiography/methods ; Humans ; Tachycardia, Supraventricular/diagnosis ; Tachycardia, Supraventricular/surgery
    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2020.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6278: Show issues Location:
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  3. Article: A Brash, Politically Incorrect, Opinionated and Brilliant Friend.

    Morady, Fred

    Arrhythmia & electrophysiology review

    2017  Volume 6, Issue 1, Page(s) 17

    Language English
    Publishing date 2017-06-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2813970-7
    ISSN 2050-3377 ; 2050-3369
    ISSN (online) 2050-3377
    ISSN 2050-3369
    DOI 10.15420/aer.2017.6.1:PP5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Conversations With Legends in Cardiac Electrophysiology.

    Daoud, Emile / Morady, Fred

    JACC. Clinical electrophysiology

    2020  Volume 6, Issue 9, Page(s) 1217.e1–1217.e6

    MeSH term(s) Communication ; Electrophysiologic Techniques, Cardiac ; Humans
    Language English
    Publishing date 2020-07-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2020.08.012
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  5. Article ; Online: Ventricular arrhythmias in patients with bicuspid aortic valves.

    Ghannam, Michael / Kovacs, Boldizsar / Liang, Jackson / Attili, Anil / Cochet, Hubert / Latchamsetty, Rakesh / Jongnarangsin, Krit / Morady, Fred / Bogun, Frank

    Journal of cardiovascular electrophysiology

    2024  

    Abstract: Introduction: Bicuspid aortic valves (BAV) are the most common congenital heart defects and the extent of ventricular arrhythmias (VA) in patients with BAV is unclear. The objective of this study is to describe VAs and late gadolinium enhancement ... ...

    Abstract Introduction: Bicuspid aortic valves (BAV) are the most common congenital heart defects and the extent of ventricular arrhythmias (VA) in patients with BAV is unclear. The objective of this study is to describe VAs and late gadolinium enhancement cardiac magnetic resonance imaging (LGE-CMR) in patients with BAV.
    Methods: A total of 19 patients with BAV (18 males, age: 58 ± 13 years) were referred for VA ablation procedures. Ten patients had BAVs at the time of ablation, nine patients had prior aortic valve replacement for a BAV. All but one patient had LGE-CMR and all patients underwent programmed ventricular stimulation at the time of the ablation.
    Results: Frequent PVCs were the targeted VAs in 17/19 patients and VT in 2/19 patients. Monomorphic ventricular tachycardia (VT) was inducible in 6 patients. A total of 15 VTs were inducible (2.5 ± 1.0 VTs per patient with a mean cycle length of 322 ± 83 msec). LGE was present in 13 patients. Patients with inducible VT had larger borderzone and core scar compared to non-inducible patients (7.8 ± 2.1 cm
    Conclusions: VAs in patients with BAV often originate from the perivalvular area and patients often have LGE and inducible VT. LGE may be due to ventricular remodeling secondary to the presence of BAV and harbors the arrhythmogenic substrate for VT.
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.16235
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    Zs.A 2863: Show issues Location:
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  6. Article ; Online: Posterior left atrial isolation is associated with a lower incidence of atrial tachycardia in patients with persistent atrial fibrillation.

    Chou, Andrew / Jongnarangsin, Krit / Yokokawa, Miki / Ghannam, Michael / Liang, Jackson J / Oral, Hakan / Morady, Fred / Chugh, Aman

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2024  

    Abstract: Background: Patients may develop atrial tachycardia (AT) after left atrial (LA) ablation of persistent atrial fibrillation (AF).: Methods: The population consisted of 101 consecutive patients (age = 64.3 ± 8.7 years, 70 males (69%), LA = 4.6 ± 0.8 cm, ...

    Abstract Background: Patients may develop atrial tachycardia (AT) after left atrial (LA) ablation of persistent atrial fibrillation (AF).
    Methods: The population consisted of 101 consecutive patients (age = 64.3 ± 8.7 years, 70 males (69%), LA = 4.6 ± 0.8 cm, ejection fraction = 48.5 ± 16%) undergoing their initial procedure for persistent AF. After pulmonary vein isolation, patients either underwent posterior LA isolation (n = 50; study group) or linear ablation at the LA roof with verification of conduction block (n = 51; control group).
    Results: A repeat procedure was performed in 17 (34%) and 28 (55%) patients in the study and control groups, respectively (p = 0.02). Patients in the study group were less likely to develop AT (9/50 [18%] vs. 18/51 [35%]; p = 0.02), roof-dependent (1/50 [2%] vs. 8/51 [16%]; p = 0.008), and multi-loop AT (6/50 [12%] vs. 14/51 [27%]; p = 0.03) as compared to controls. Among various factors, only posterior LA isolation was associated with a lower likelihood of AT recurrence and roof tachycardia at redo procedure (OR, 0.37; 95% CI, 0.1 to 1.00, p = 0.05, and OR, 0.1, 95% CI, 0.01 to 0.96; p < 0.05, respectively).
    Conclusions: In patients with persistent AF, posterior LA isolation is associated with a lower risk of a redo procedure, roof-dependent macro-reentry, and post-ablation AT in general as compared to controls who only received roof ablation. Posterior LA isolation also obviates the need for pacing maneuvers, and may be a more definitive endpoint than linear ablation at the LA roof.
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-024-01769-z
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    Zs.A 5214: Show issues Location:
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  7. Article: Catheter ablation of supraventricular arrhythmias: state of the art.

    Morady, Fred

    Heart rhythm

    2013  Volume 1, Issue 5 Suppl, Page(s) 67C–84C

    MeSH term(s) Catheter Ablation/history ; Catheter Ablation/methods ; Electrophysiologic Techniques, Cardiac/history ; Electrophysiologic Techniques, Cardiac/methods ; Forecasting ; History, 20th Century ; History, 21st Century ; Humans ; Tachycardia, Supraventricular/history ; Tachycardia, Supraventricular/surgery
    Language English
    Publishing date 2013-04-09
    Publishing country United States
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2004.10.020
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  8. Article: Source Determination in Atrial Fibrillation.

    Latchamsetty, Rakesh / Morady, Fred

    Arrhythmia & electrophysiology review

    2018  Volume 7, Issue 3, Page(s) 165–168

    Abstract: Techniques to ablate persistent atrial fibrillation (AF) continue to evolve. Recent technological and strategic innovations have included a focus on mapping and ablating AF sources. These attempts have not yet yielded a consistent improvement in clinical ...

    Abstract Techniques to ablate persistent atrial fibrillation (AF) continue to evolve. Recent technological and strategic innovations have included a focus on mapping and ablating AF sources. These attempts have not yet yielded a consistent improvement in clinical outcomes following AF ablation. Advancements in these techniques in the next few years, however, may enhance our ability to map and ablate AF as well as further our understanding of the mechanisms behind AF initiation, perpetuation, and recurrence.
    Language English
    Publishing date 2018-10-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2813970-7
    ISSN 2050-3377 ; 2050-3369
    ISSN (online) 2050-3377
    ISSN 2050-3369
    DOI 10.15420/aer:2018:25:2
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  9. Article ; Online: Incidental left atrial appendage isolation after catheter ablation of persistent atrial fibrillation: Mechanisms and long-term risk of thromboembolism.

    Ghannam, Michael / Jongnarangsin, Krit / Emami, Hamed / Yokokawa, Miki / Liang, Jackson J / Saeed, Mohammed / Oral, Hakan / Morady, Fred / Chugh, Aman

    Journal of cardiovascular electrophysiology

    2023  Volume 34, Issue 5, Page(s) 1152–1161

    Abstract: Introduction: Incidental left atrial appendage (LAA) isolation may occur during radiofrequency ablation of persistent atrial fibrillation (AF). The study aims to describe the mechanisms and long-term thromboembolic risk related to incidental LAA ... ...

    Abstract Introduction: Incidental left atrial appendage (LAA) isolation may occur during radiofrequency ablation of persistent atrial fibrillation (AF). The study aims to describe the mechanisms and long-term thromboembolic risk related to incidental LAA isolation.
    Methods: Patients who experienced incidental LAA isolation after AF ablation were included. Culprit sites where ablation resulted in LAA isolation were identified. Thromboembolic risk despite oral anticoagulation (OAC) was compared to that in a propensity-matched control group without LAA isolation.
    Results: Forty-one patients with LAA isolation, and 82 matched patients without LAA isolation were included. The patient age, ejection fraction, LA diameter, and CHA
    Conclusions: Incidental LAA isolation may occur during ablation of atrial arrhythmias in the vicinity of, or even at sites remote from the appendage. Patients with incidental LAA isolation had higher rates of thromboembolism compared to patients without isolation. Since thromboembolism may occur despite prescription for OAC, the risks of LAA isolation must be weighed against clinical benefit and appendage occlusion devices should be considered in vulnerable patients.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Atrial Appendage/surgery ; Treatment Outcome ; Thromboembolism/etiology ; Thromboembolism/prevention & control ; Catheter Ablation/methods
    Language English
    Publishing date 2023-04-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025989-2
    ISSN 1540-8167 ; 1045-3873
    ISSN (online) 1540-8167
    ISSN 1045-3873
    DOI 10.1111/jce.15889
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2863: Show issues Location:
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  10. Article ; Online: Implications of the anatomy of papillary muscle connections for mapping and ablation of focal ventricular arrhythmias.

    Huntrakul, Anurut / Yokokawa, Miki / Ghannam, Michael / Liang, Jackson / Patel, Smita / Cochet, Hubert / Latchamsetty, Rakesh / Jongnarangsin, Krit / Morady, Fred / Bogun, Frank

    Heart rhythm

    2023  Volume 20, Issue 10, Page(s) 1445–1454

    Abstract: Background: Ventricular arrhythmias (VAs) originating from papillary muscles (PAPs) can be challenging when targeted with catheter ablation. Reasons may include premature ventricular complex pleomorphism, structurally abnormal PAPs, or unusual origins ... ...

    Abstract Background: Ventricular arrhythmias (VAs) originating from papillary muscles (PAPs) can be challenging when targeted with catheter ablation. Reasons may include premature ventricular complex pleomorphism, structurally abnormal PAPs, or unusual origins of VAs from PAP-myocardial connections (PAP-MYCs).
    Objective: The purpose of this study was to correlate PAP anatomy with mapping and ablation of PAP VAs.
    Methods: In a series of 43 consecutive patients with frequent PAP arrhythmias referred for ablation, the anatomy and structure of PAPs and VA origins were analyzed using multimodality imaging. Successful ablation sites were analyzed for location on the PAP body or a PAP-MYC.
    Results: In a total of 17 of 43 patients (40%), VAs originated from a PAP-MYC (in 5 of 17 patients, the PAP inserted into the mitral valve anulus); and in 41 patients, VAs originated from a PAP body. VAs from a PAP-MYC more often had delayed R-wave transition than did other PAP VAs (69% vs 28%; P < .001). Patients with failed procedures had more PAP-MYCs (24.8 ± 8 PAP-MYCs per patient vs 16 ± 7 PAP-MYCs per patient; P < .001).
    Conclusion: Multimodality imaging identifies anatomic details of PAPs that facilitate mapping and ablation of VAs. In more than a third of patients with PAP VAs, VAs originate from connections between PAPs and the surrounding myocardium or between other PAPs. VA electrocardiographic morphologies are different when VAs originate from PAP-connection sites as compared with VAs originating from the PAP body.
    MeSH term(s) Humans ; Papillary Muscles/surgery ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/surgery ; Ventricular Premature Complexes/diagnosis ; Ventricular Premature Complexes/surgery ; Electrocardiography ; Mitral Valve/surgery ; Catheter Ablation ; Heart Ventricles
    Language English
    Publishing date 2023-06-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2023.06.009
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