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Article: Diagnosis and treatment of early active rheumatoid arthritis.

Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2009 Volume 23, Issue 12, Page(s) 956–961

Abstract: A 59-year-old patient comes to a community pharmacy with unexplained, worsening bilateral foot pain and inflammation. Following evaluation of the situation, the pharmacist suggests that the patient has rheumatoid arthritis (RA). After a visit and ... ...

Abstract	A 59-year-old patient comes to a community pharmacy with unexplained, worsening bilateral foot pain and inflammation. Following evaluation of the situation, the pharmacist suggests that the patient has rheumatoid arthritis (RA). After a visit and consultation with her physician, the patient begins a complicated, rapidly evolving therapeutic regimen for RA. Through extensive counseling and education, the pharmacist is able to help the patient better manage her new medication regimen and understand expected outcomes. Pharmacists can play a very active role in helping patients with RA manage their therapies to optimize health outcomes.
MeSH term(s)	Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Community Pharmacy Services/organization & administration ; Female ; Humans ; Middle Aged ; Patient Education as Topic ; Pharmacists ; Professional Role ; Referral and Consultation
Chemical Substances	Antirheumatic Agents
Language	English
Publishing date	2009-03-03
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/tcp.n.2008.956
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Article ; Online: Treatment of postherpetic neuralgia: focus on pregabalin.

Cappuzzo, Kimberly A

Clinical interventions in aging

2009 Volume 4, Page(s) 17–23

Abstract: Postherpetic neuralgia (PHN) is a devastating, chronic pain syndrome that can develop following an outbreak of herpes zoster and becomes increasingly common as patients age. PHN can be difficult to treat and often requires trials of multiple agents to ... ...

Abstract	Postherpetic neuralgia (PHN) is a devastating, chronic pain syndrome that can develop following an outbreak of herpes zoster and becomes increasingly common as patients age. PHN can be difficult to treat and often requires trials of multiple agents to achieve significant pain relief. Pregabalin is the newest agent to gain approval for PHN. Data suggest efficacy for relief of pain and sleep disturbance secondary to PHN in affected patients. Although there are no head-to-head comparisons, pregabalin appears comparable to gabapentin and other first-line agents for treating PHN.
MeSH term(s)	Aged ; Analgesics/administration & dosage ; Analgesics/adverse effects ; Analgesics/pharmacokinetics ; Analgesics/pharmacology ; Analgesics/therapeutic use ; Dose-Response Relationship, Drug ; Humans ; Neuralgia, Postherpetic/drug therapy ; Neuralgia, Postherpetic/physiopathology ; Pregabalin ; gamma-Aminobutyric Acid/administration & dosage ; gamma-Aminobutyric Acid/adverse effects ; gamma-Aminobutyric Acid/analogs & derivatives ; gamma-Aminobutyric Acid/pharmacokinetics ; gamma-Aminobutyric Acid/pharmacology ; gamma-Aminobutyric Acid/therapeutic use
Chemical Substances	Analgesics ; Pregabalin (55JG375S6M) ; gamma-Aminobutyric Acid (56-12-2)
Language	English
Publishing date	2009-05-14
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2364924-0
ISSN	1178-1998 ; 1176-9092
ISSN (online)	1178-1998
ISSN	1176-9092
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Article: Communicating with seniors and their caregivers.

Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2008 Volume 23, Issue 9, Page(s) 695–709

Abstract: Conducting a patient interview is an important initial step in evaluating patients and monitoring their drug therapy. Communicating with seniors can be challenging, and ensuring optimal communication is key to a successful interview. Pharmacists can help ...

Abstract	Conducting a patient interview is an important initial step in evaluating patients and monitoring their drug therapy. Communicating with seniors can be challenging, and ensuring optimal communication is key to a successful interview. Pharmacists can help patients optimize patient health care outcomes by understanding and preparing for potential factors that can influence the communication process, being prepared for the interview, and using good communication techniques.
MeSH term(s)	Aged/physiology ; Aged/psychology ; Attitude of Health Personnel ; Caregivers/psychology ; Communication ; Communication Barriers ; Confidentiality ; Humans ; Pharmacists ; Professional-Patient Relations
Language	English
Publishing date	2008-05-15
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/tcp.n.2008.695
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Zs.MO 209: Show issues

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Article: Herbal product use in a patient with polypharmacy.

Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2007 Volume 21, Issue 11, Page(s) 911–915

Abstract: A 70-year-old homebound patient was experiencing new onset porthostatic hypotension and lightheadedness. The pharmacist conducted a thorough medication review, which revealed the use of several herbal products, including St. John's wort, in addition to ... ...

Abstract	A 70-year-old homebound patient was experiencing new onset porthostatic hypotension and lightheadedness. The pharmacist conducted a thorough medication review, which revealed the use of several herbal products, including St. John's wort, in addition to several prescription medications. The pharmacist counseled the patient on the potential hazards of using herbal products with prescription medications. This prompted the patient to discontinue all herbal supplements with the subsequent resolution of his lightheadedness and orthostasis. He also experienced improvement in his pain control. Pharmacists need to be vigilant in establishing a dialogue with their patients about the pros and cons of herbal product use, particularly with prescription medications.
MeSH term(s)	Aged ; Analgesics, Opioid/therapeutic use ; Dizziness/etiology ; Herb-Drug Interactions ; Humans ; Hypotension, Orthostatic/etiology ; Male ; Methadone/therapeutic use ; Osteoarthritis/drug therapy ; Pain/drug therapy ; Plants, Medicinal/adverse effects ; Polypharmacy
Chemical Substances	Analgesics, Opioid ; Methadone (UC6VBE7V1Z)
Language	English
Publishing date	2007-01-22
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/tcp.n.2006.911
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Zs.A 3412: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 209: Show issues

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Article: Anticoagulation in elderly patients who fall frequently: a therapeutic dilemma.

Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2006 Volume 20, Issue 7, Page(s) 601–605

Abstract: There is general agreement that patients with persistent atrial fibrillation, who are at risk of having a stroke, need to be anticoagulated. However, clinicians often are in a difficult dilemma when these patients also are at increased risk of falling. ... ...

Abstract	There is general agreement that patients with persistent atrial fibrillation, who are at risk of having a stroke, need to be anticoagulated. However, clinicians often are in a difficult dilemma when these patients also are at increased risk of falling. Falls can lead to serious injuries in anticoagulated individuals, including intracranial hemorrhages. This case study describes an 88-year-old patient with a history of falling. She received multiple injuries following a fall, including a subdural hematoma. Warfarin was among the patient's many medications. Upon admission to the hospital this patient had a supratherapeutic INR that most likely contributed to her injuries. A question facing the medical team was should she continue to receive warfarin to prevent stroke after discharge from the hospital? Much controversy exists over whether older patients receiving anticoagulation therapy are at increased risk of major hemorrhagic complications. This article discusses the relationship between anticoagulation, falling, and the risks of hemorrhagic events. It also discusses opinions on when to restart anticoagulation following resolution of the subdural hematoma. In addition, the patient was taking multiple medications that are known to contribute to falls in older people. Recommendations for lowering this patient's fall risks are presented.
Language	English
Publishing date	2006-03-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/tcp.n.2005.601
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3412: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 209: Show issues

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Article: Review of isolated systolic hypertension in older adults.

Kamath, Neetha / Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2010 Volume 25, Issue 6, Page(s) 374–378

Abstract: A 75-year-old patient comes to a community pharmacy to refill her blood pressure (BP) medications. She approached the pharmacist complaining of a headache and an unusually high BP reading that she had gotten from the automated machine. The patient was ... ...

Abstract	A 75-year-old patient comes to a community pharmacy to refill her blood pressure (BP) medications. She approached the pharmacist complaining of a headache and an unusually high BP reading that she had gotten from the automated machine. The patient was unaware of her usual BP, but knew that the reading was unusually high for her. Following evaluation of the patient and after obtaining several high systolic BP readings, the pharmacist appropriately calls for an ambulance. At the hospital, the patient is told she is in need of triple-bypass surgery. After her hospital stay, the patient is now diligent about refilling her BP medications on time and consistently monitors and records her BP at home. Isolated systolic hypertension is a growing concern in older adults, and a large percentage of adults are not appropriately managed. Pharmacists play an active role in educating patients on the importance of high BP monitoring and adherence to minimize the risk of cardiovascular events.
MeSH term(s)	Aged ; Antihypertensive Agents/therapeutic use ; Blood Pressure ; Blood Pressure Determination ; Community Pharmacy Services/organization & administration ; Female ; Humans ; Hypertension/diagnosis ; Hypertension/drug therapy ; Hypertension/physiopathology ; Medication Adherence ; Patient Education as Topic/methods ; Pharmacists/organization & administration ; Professional Role ; Systole
Chemical Substances	Antihypertensive Agents
Language	English
Publishing date	2010-06
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/TCP.n.2010.374
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3412: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 209: Show issues

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Article ; Online: Treatment of postherpetic neuralgia

Kimberly A Cappuzzo

Clinical Interventions in Aging, Vol 2009, Iss default, Pp 17-

focus on pregabalin

2008 Volume 23

Abstract: Kimberly A CappuzzoThe Geriatric Pharmacotherapy Program, Virginia Commonwealth University ...

Abstract	Kimberly A CappuzzoThe Geriatric Pharmacotherapy Program, Virginia Commonwealth University, School of Pharmacy, Richmond, Virginia, USAAbstract: Postherpetic neuralgia (PHN) is a devastating, chronic pain syndrome that can develop following an outbreak of herpes zoster and becomes increasingly common as patients age. PHN can be difficult to treat and often requires trials of multiple agents to achieve significant pain relief. Pregabalin is the newest agent to gain approval for PHN. Data suggest efficacy for relief of pain and sleep disturbance secondary to PHN in affected patients. Although there are no head-to-head comparisons, pregabalin appears comparable to gabapentin and other first-line agents for treating PHN.Keywords: pregabalin, postherpetic neuralgia, neuropathic pain
Keywords	Medicine (General) ; R5-920 ; Medicine ; R ; DOAJ:Medicine (General) ; DOAJ:Health Sciences ; Geriatrics ; RC952-954.6
Language	English
Publishing date	2008-12-01T00:00:00Z
Publisher	Dove Medical Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Postherpetic neuralgia in an elderly patient.

Cappuzzo, Kimberly A / Krogsund, René Roberts

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2007 Volume 22, Issue 7, Page(s) 593–598

Abstract: A 67-year-old patient presented to the community pharmacy with poorly controlled postherpetic neuralgia (PHN) pain following an episode of herpes zoster. The clinical pharmacist did a medication review and found that, although the patient was receiving ... ...

Abstract	A 67-year-old patient presented to the community pharmacy with poorly controlled postherpetic neuralgia (PHN) pain following an episode of herpes zoster. The clinical pharmacist did a medication review and found that, although the patient was receiving medications proven effective in the treatment of PHN, she was not receiving optimal therapy. Additionally, the patient was experiencing intolerable side effects. The pharmacist provided recommendations to the patient's primary care physician that ultimately improved the patient's pain control. Managing PHN pain requires practitioners to be vigilant in titrating pain regimens and trying various combinations of therapies with different mechanisms of action. Such an approach is one that tailors medication therapy to each individual patient, provides the most relief, and restores a patient's quality of life.
MeSH term(s)	Aged ; Consultants ; Drug-Related Side Effects and Adverse Reactions ; Female ; Herpes Zoster/complications ; Herpes Zoster/drug therapy ; Humans ; Neuralgia, Postherpetic/drug therapy ; Neuralgia, Postherpetic/etiology ; Pain/drug therapy ; Pain/etiology ; Pharmacists ; Professional Role ; Treatment Outcome
Language	English
Publishing date	2007-08-11
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/tcp.n.2007.593
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.MO 209: Show issues

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Article: Vitamin D deficiency: appropriate replenishment therapies and the effects of vitamin D toxicity.

Carlton, Sean / Clopton, David / Cappuzzo, Kimberly A

The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

2010 Volume 25, Issue 3, Page(s) 171–177

Abstract: An 84-year-old patient diagnosed with a vitamin D deficiency was given a prescription for ergocalciferol (vitamin D2) 50,000 units weekly. The prescription was incorrectly filled for ergocalciferol 50,000 units daily. Incorrect therapy continued for two ... ...

Abstract	An 84-year-old patient diagnosed with a vitamin D deficiency was given a prescription for ergocalciferol (vitamin D2) 50,000 units weekly. The prescription was incorrectly filled for ergocalciferol 50,000 units daily. Incorrect therapy continued for two months. The patient's vitamin D level increased from < 7.0 ng/mL to 100 ng/mL over a six-month span. The patient complained of decreased appetite and significant weight loss and presented with an elevated International Normalized Ratio at a pharmacist-run anticoagulation clinic. In conjunction with the physician, the pharmacist discontinued vitamin D therapy and monitored levels.Vitamin D plays an integral role in the body's ability to absorb calcium and regulate calcium homeostasis. Further benefits have been reported regarding the role of vitamin D in muscle strength, cardiovascular health, and in preventing osteoporosis and falls. Vitamin D deficiency is widespread in the older adult population as a result of low dietary intake, decreased sun exposure, decreased intrinsic vitamin D production, and decreased vitamin D receptor activity. Replenishment using high-dose ergocalciferol is one common replenishment therapy. Patients also are able to supplement with nonprescription vitamin D products of varying strengths. While many older patients can be expected to have vitamin D deficiencies, pharmacists should be aware of appropriate replenishment therapies and correct dosing of different vitamin D products. Pharmacists also should be familiar with possible toxic effects of vitamin D, particularly as public awareness of benefits continues to increase.
MeSH term(s)	Aged, 80 and over ; Appetite ; Dose-Response Relationship, Drug ; Ergocalciferols/administration & dosage ; Ergocalciferols/adverse effects ; Ergocalciferols/therapeutic use ; Female ; Humans ; International Normalized Ratio ; Vitamin D Deficiency/drug therapy ; Vitamins/administration & dosage ; Vitamins/adverse effects ; Vitamins/therapeutic use ; Weight Loss/drug effects
Chemical Substances	Ergocalciferols ; Vitamins
Language	English
Publishing date	2010-03
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1107921-6
ISSN	2331-0936 ; 0888-5109
ISSN (online)	2331-0936
ISSN	0888-5109
DOI	10.4140/TCP.n.2010.171
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 3412: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 209: Show issues

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Article: Teriparatide for severe osteoporosis.

Cappuzzo, Kimberly A / Delafuente, Jeffrey C

The Annals of pharmacotherapy

2004 Volume 38, Issue 2, Page(s) 294–302

Abstract: Objective: To review the pharmacology, toxicology, pharmacokinetics, pharmacodynamics, efficacy, safety, therapeutic controversies, administration, patient counseling, and formulary recommendations for teriparatide (rDNA origin).: Data sources: A ... ...

Abstract	Objective: To review the pharmacology, toxicology, pharmacokinetics, pharmacodynamics, efficacy, safety, therapeutic controversies, administration, patient counseling, and formulary recommendations for teriparatide (rDNA origin). Data sources: A MEDLINE search (1966-May 2003) of articles using the key words parathyroid hormone and osteoporosis, parathyroid hormone and fracture, and teriparatide was conducted to identify relevant literature in the English language. Additional references were obtained from bibliographies of those articles. Some clinical trial data not yet published were obtained from the manufacturer. Study selection and data extraction: All articles obtained from the data sources were reviewed; all data deemed relevant were included. Data synthesis: Teriparatide, recombinant human parathyroid hormone (1-34) [rhPTH (1-34)], is the first anabolic agent to treat postmenopausal women with osteoporosis and men with idiopathic or hypogonadal osteoporosis who are at high risk for osteoporotic fracture. Daily subcutaneous injections of teriparatide significantly increase both spine and hip bone-mineral density (BMD) while decreasing the incidence of fractures in both women and men. Common adverse effects noted with teriparatide use were nausea, headache, dizziness, and arthralgias. An increased incidence of osteosarcoma in rats during preclinical trials with teriparatide led to a black box warning for the drug. Conclusions: Teriparatide substantially increases spine and hip BMD and may offer additional benefits to patients with severe osteoporosis. Clinical trials comparing teriparatide with other available agents to treat osteoporosis are needed to more clearly define its place in therapy. Long-term safety and efficacy are not known.
MeSH term(s)	Adult ; Aged ; Animals ; Biological Availability ; Calcium/blood ; Calcium/urine ; Counseling ; Female ; Fractures, Bone/etiology ; Half-Life ; Humans ; Male ; Middle Aged ; Neoplasms, Experimental/chemically induced ; Osteoporosis/complications ; Osteoporosis/drug therapy ; Randomized Controlled Trials as Topic ; Teriparatide/adverse effects ; Teriparatide/pharmacokinetics ; Teriparatide/therapeutic use
Chemical Substances	Teriparatide (10T9CSU89I) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2004-02
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1101370-9
ISSN	1542-6270 ; 1060-0280
ISSN (online)	1542-6270
ISSN	1060-0280
DOI	10.1345/aph.1D353
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