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  1. Article: Chaenomelin, a New Phenolic Glycoside, and Anti-

    Kim, Kyung Ah / Kang, Dong-Min / Ko, Yoon-Joo / Ra, Moon-Jin / Jung, Sang-Mi / Yu, Jeong-Nam / Ahn, Mi-Jeong / Kim, Ki Hyun

    Plants (Basel, Switzerland)

    2024  Volume 13, Issue 5

    Abstract: ... Salix ... ...

    Abstract Salix chaenomeloides
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants13050701
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Adjuvant therapy with toceranib for hepatocellular carcinoma and cholangiocarcinoma in a Pomeranian.

    Choi, Lee / Choi, Jin-Young / Yoon, Hun-Young / Bae, Kieun / Yoon, Kyong-Ah / Kim, Jung-Hyun

    Veterinarni medicina

    2023  Volume 68, Issue 2, Page(s) 83–89

    Abstract: A 10-year-old spayed female Pomeranian dog was referred for hepatic mass evaluation. Blood tests revealed mildly elevated alkaline phosphatase activities. Computed tomography revealed a mass with multiple nodules on the right hepatic medial lobe adjacent ...

    Abstract A 10-year-old spayed female Pomeranian dog was referred for hepatic mass evaluation. Blood tests revealed mildly elevated alkaline phosphatase activities. Computed tomography revealed a mass with multiple nodules on the right hepatic medial lobe adjacent to the caudal
    Language English
    Publishing date 2023-02-23
    Publishing country Czech Republic
    Document type Case Reports
    ZDB-ID 412227-6
    ISSN 0375-8427 ; 0590-5214
    ISSN 0375-8427 ; 0590-5214
    DOI 10.17221/49/2022-VETMED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Exercise as an antidepressant: exploring its therapeutic potential.

    Hwang, Dong-Joo / Koo, Jung-Hoon / Kim, Tae-Kyung / Jang, Yong-Chul / Hyun, Ah-Hyun / Yook, Jang-Soo / Yoon, Chang-Sun / Cho, Joon-Yong

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1259711

    Abstract: The COVID-19 pandemic has increased the prevalence of depressive disorders worldwide, requiring alternative treatments beyond medication and psychotherapy. Exercise has positive effects on the brain; therefore, it has emerged as a promising therapeutic ... ...

    Abstract The COVID-19 pandemic has increased the prevalence of depressive disorders worldwide, requiring alternative treatments beyond medication and psychotherapy. Exercise has positive effects on the brain; therefore, it has emerged as a promising therapeutic option for individuals with depression. Considerable research involving humans and animals offers compelling evidence to support the mental health benefits of physical activity or exercise mediated by the regulation of complex theoretical paradigms. However, challenges such as conducting long-term follow-up assessments and considering individual characteristics remain in human studies despite extensive efforts. While animal studies provide valuable insights into the potential benefits of exercise and its impact on outcomes related to depression and anxiety in rodents exposed to different stress paradigms, translating the findings to humans requires careful evaluation. More research is needed to establish precise exercise prescription guidelines and to better understand the complex relationship between exercise and depressive disorders. Therefore, this concise review explores the evidence supporting exercise intervention as an antidepressant treatment and its underlying mechanisms.
    Language English
    Publishing date 2023-09-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1259711
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Identification of CT-derived Internal Area in Failed Surgical Stented Bioprostheses for Valve-in-Valve Implantation.

    Lee, Seung-Ah / Koo, Hyun Jung / Kang, Do-Yoon / Ahn, Jung-Min / Park, Duk-Woo / Park, Seung-Jung / Kim, Dae-Hee / Kang, Joon-Won / Yang, Dong Hyun

    Radiology. Cardiothoracic imaging

    2024  Volume 5, Issue 6, Page(s) e230103

    MeSH term(s) Bioprosthesis/adverse effects ; Aortic Valve/diagnostic imaging ; Transcatheter Aortic Valve Replacement ; Tomography, X-Ray Computed
    Language English
    Publishing date 2024-01-02
    Publishing country United States
    Document type Journal Article
    ISSN 2638-6135
    ISSN (online) 2638-6135
    DOI 10.1148/ryct.230103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Comparison of posttreatment stability after total mandibular arch distalization with mini-implants and mandibular setback surgery.

    Kook, Yoon-Ah / Choi, Tae-Hyun / Park, Jae Hyun / Kim, So-Hyun / Lee, Nam-Ki

    The Angle orthodontist

    2023  Volume 94, Issue 2, Page(s) 159–167

    Abstract: Objectives: To compare posttreatment stability in skeletal Class III patients between those treated by total mandibular arch distalization (TMAD) with buccal mini-implants and those by mandibular setback surgery (MSS).: Materials and methods: The ... ...

    Abstract Objectives: To compare posttreatment stability in skeletal Class III patients between those treated by total mandibular arch distalization (TMAD) with buccal mini-implants and those by mandibular setback surgery (MSS).
    Materials and methods: The samples included 40 Class III adults, 20 treated by TMAD using buccal interradicular mini-implants and 20 treated with MSS. Lateral cephalograms were taken at pretreatment, posttreatment, and at least 1-year follow-up, and 24 variables were compared using statistical analysis.
    Results: Mandibular first molars moved distally 1.9 mm with intrusion of 1.1 mm after treatment in the TMAD group. The mandibular incisors moved distally by 2.3 mm. The MSS group exhibited a significant skeletal change of the mandible, whereas the TMAD group did not. During retention, there were no skeletal or dental changes other than 0.6 mm labial movement of the mandibular incisors (P < .05) in the MSS group. There was 1.4° of mesial tipping (P < .01) and 0.4 mm of mesial movement of the mandibular molars and 1.9° of labial tipping (P < .001) and 0.8 mm of mesial movement of the mandibular incisors in the TMAD group. These dental changes were not significantly different between the two groups.
    Conclusions: The TMAD group showed a slightly decreased overjet with labial tipping of the mandibular incisors and mesial tipping of the first molars during retention. Posttreatment stability of the mandibular dentition was not significantly different between the groups. It can be useful to plan camouflage treatment by TMAD with mini-implants in mild-to-moderate Class III patients.
    MeSH term(s) Adult ; Humans ; Maxilla ; Tooth Movement Techniques ; Cephalometry ; Mandible/surgery ; Overbite
    Language English
    Publishing date 2023-12-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390289-4
    ISSN 1945-7103 ; 0003-3219
    ISSN (online) 1945-7103
    ISSN 0003-3219
    DOI 10.2319/062723-447.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Huge Primary Pleural Cyst Mimicking an Exophytic Echinococcal Cyst: A Case Report.

    Yoon, Jaeshin / Lim, Hyun Ah / Kim, Hee Kyung / Kim, Kyung Soo

    Journal of chest surgery

    2023  Volume 56, Issue 4, Page(s) 286–289

    Abstract: A 58-year-old woman presented with an incidental asymptomatic mass occupying the entire right lower thorax. A radiologic study demonstrated a huge cystic mass, initially suggestive of an exophytic echinococcal cyst. After unsuccessful catheter drainage, ... ...

    Abstract A 58-year-old woman presented with an incidental asymptomatic mass occupying the entire right lower thorax. A radiologic study demonstrated a huge cystic mass, initially suggestive of an exophytic echinococcal cyst. After unsuccessful catheter drainage, the patient was referred for surgery, and curative resection of the lung-, heart-, and diaphragm-compressing mass was performed under video-assisted thoracoscopic surgery. Culture studies revealed no growth of parasitic, bacterial, or fungal infections, and the final pathological result confirmed a primary pleural cyst. Thoracic cystic masses mostly manifest as bronchogenic or pericardial cysts, while primary pleural cysts have rarely been reported. We present a rare case of a huge pleural cyst that initially mimicked an echinococcal cyst.
    Language English
    Publishing date 2023-03-06
    Publishing country Korea (South)
    Document type Case Reports
    ISSN 2765-1606
    ISSN 2765-1606
    DOI 10.5090/jcs.22.137
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Oxidative Stress-Mediated RUNX3 Mislocalization Occurs Via Jun Activation Domain-Binding Protein 1 and Histone Modification.

    Kang, Kyoung Ah / Piao, Mei Jing / Fernando, Pincha Devage Sameera Madushan / Herath, Herath Mudiyanselage Udari Lakmini / Boo, Hye-Jin / Yoon, Sang Pil / Hyun, Jin Won

    Applied biochemistry and biotechnology

    2024  

    Abstract: Runt domain transcription factor 3 (RUNX3) suppresses many different cancer types and is disabled by mutations, epigenetic repression, or cytoplasmic mislocalization. In this study, we investigated whether oxidative stress is associated with RUNX3 ... ...

    Abstract Runt domain transcription factor 3 (RUNX3) suppresses many different cancer types and is disabled by mutations, epigenetic repression, or cytoplasmic mislocalization. In this study, we investigated whether oxidative stress is associated with RUNX3 accumulation from the nucleus to the cytoplasm in terms of histone modification. Oxidative stress elevated histone deacetylase (HDAC) level and lowered that of histone acetyltransferase. In addition, oxidative stress decreased the expression of mixed lineage leukemia (MLL), a histone methyltransferase, but increased the expression of euchromatic histone-lysine N-methyltransferase 2 (EHMT2/G9a), which is also a histone methyltransferase. Moreover, oxidative stress-induced RUNX3 phosphorylation, Src activation, and Jun activation domain-binding protein 1 (JAB1) expression were inhibited by knockdown of HDAC and G9a, restoring the nuclear localization of RUNX3 under oxidative stress. Cytoplasmic RUNX3 localization was followed by oxidative stress-induced histone modification, activated Src along with RUNX3 phosphorylation, and induction of JAB1, resulting in RUNX3 inactivation.
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392344-7
    ISSN 1559-0291 ; 0273-2289
    ISSN (online) 1559-0291
    ISSN 0273-2289
    DOI 10.1007/s12010-024-04944-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Naringenin Induces Cellular Apoptosis in Melanoma Cells

    Fernando, Pincha Devage Sameera Madushan / Zhen, Ao Xuan / Piao, Mei Jing / Herath, Herath Mudiyanselage Udari Lakmini / Kang, Kyoung Ah / Yoon, Sang-Pil / Boo, Hye-Jin / Hyun, Chang Lim / Hyun, Jin Won

    Anticancer research

    2024  Volume 44, Issue 3, Page(s) 1079–1086

    Abstract: Background/aim: Melanoma is a prevalent malignant tumor that arises from melanocytes. The treatment of malignant melanoma has become challenging due to the development of drug resistance. It is, therefore, imperative to identify novel therapeutic drug ... ...

    Abstract Background/aim: Melanoma is a prevalent malignant tumor that arises from melanocytes. The treatment of malignant melanoma has become challenging due to the development of drug resistance. It is, therefore, imperative to identify novel therapeutic drug candidates for controlling malignant melanoma. Naringenin is a flavonoid abundant in oranges and other citrus fruits and recognized for its numerous medicinal benefits. The objective of the study was to assess the anti-carcinogenic potential of naringenin by evaluating its ability to regulate the cellular production of reactive oxygen species (ROS) and its effect on mitochondrial function and apoptosis in melanoma cells.
    Materials and methods: Cell viability, intracellular ROS levels, cell apoptosis, and mitochondrial functions were evaluated.
    Results: Naringenin decreased melanoma cell viability and triggered generation of ROS, leading to cell apoptosis. In addition, it stimulated mitochondrial damage in melanoma cells by elevating the levels of Ca
    Conclusion: Naringenin caused oxidative stress and mitochondrial damage, and activated autophagy in melanoma cells, leading to cell apoptosis. These findings indicate the potential of naringenin as a new therapeutic candidate for melanoma.
    MeSH term(s) Humans ; Reactive Oxygen Species/metabolism ; Melanoma/pathology ; Cell Line, Tumor ; Apoptosis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Membrane Potential, Mitochondrial ; Flavanones
    Chemical Substances Reactive Oxygen Species ; naringenin (HN5425SBF2) ; Proto-Oncogene Proteins c-bcl-2 ; Flavanones
    Language English
    Publishing date 2024-02-29
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16903
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Photobiomodulation Recovers the Submandibular Gland in Vismodegib-Treated Rats.

    Kim, Yoon-Ah / Abueva, Celine / Padalhin, Andrew / Park, So Young / Lee, Ha Young / Ryu, Hyun-Seok / Chung, Phil-Sang / Woo, Seung Hoon

    Photobiomodulation, photomedicine, and laser surgery

    2024  Volume 42, Issue 2, Page(s) 159–167

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Rats ; Animals ; Submandibular Gland/metabolism ; Zinc Finger Protein GLI1/metabolism ; Zinc Finger Protein GLI1/pharmacology ; Low-Level Light Therapy ; Signal Transduction ; Anilides ; Pyridines
    Chemical Substances HhAntag691 ; Zinc Finger Protein GLI1 ; Anilides ; Pyridines
    Language English
    Publishing date 2024-02-02
    Publishing country United States
    Document type Journal Article
    ISSN 2578-5478
    ISSN (online) 2578-5478
    DOI 10.1089/photob.2023.0063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Evaluation of Non-Thermal Decontamination Processes to Have the Equivalence of Thermal Process in Raw Ground Chicken.

    Park, Eunyoung / Park, Sangeun / Hwang, Jeong Hyeon / Jung, Ah Hyun / Park, Sung Hee / Yoon, Yohan

    Food science of animal resources

    2022  Volume 42, Issue 1, Page(s) 142–152

    Abstract: The present study was aimed at examining the antibacterial effects of non-thermal decontamination processes, which are equivalent to thermal treatment, to ensure microbiological safety of raw ground chicken. ...

    Abstract The present study was aimed at examining the antibacterial effects of non-thermal decontamination processes, which are equivalent to thermal treatment, to ensure microbiological safety of raw ground chicken.
    Language English
    Publishing date 2022-01-01
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3016289-0
    ISSN 2636-0780 ; 2636-0772
    ISSN (online) 2636-0780
    ISSN 2636-0772
    DOI 10.5851/kosfa.2021.e69
    Database MEDical Literature Analysis and Retrieval System OnLINE

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