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Article ; Online: Comparison of prilocaine/lidocaine cream with piroxicam gel for reducing pain during cannulation of arteriovenous fistula for adults undergoing haemodialysis: A randomized crossover clinical trial.

Shaheen, Samia / Arshad, Abdul Rehman / Khattak, Muhammad Adnan Khan

2022 , Page(s) 11297298221142375

Abstract: Background: Pain is a traumatic experience for most patients on hemodialysis. In this trial, we compared prilocaine/lidocaine cream with piroxicam gel for pain reduction during arteriovenous fistula needling.: Methods: This randomized double-blind ... ...

Abstract	Background: Pain is a traumatic experience for most patients on hemodialysis. In this trial, we compared prilocaine/lidocaine cream with piroxicam gel for pain reduction during arteriovenous fistula needling. Methods: This randomized double-blind crossover clinical trial was done at dialysis unit of a tertiary care hospital from June to August 2022. Adult patients, aged 18-75 years, on maintenance hemodialysis through an arteriovenous fistula were selected randomly. Pain severity during needling of fistula was assessed during initial two hemodialysis sessions without application of any drug. Patients were then randomized into two groups receiving 5% prilocaine/lidocaine cream or 0.5% piroxicam gel 1 h before the next two hemodialysis sessions. After a 7-day washout period, patients crossed over to other groups for another two hemodialysis sessions. Pain was assessed on all these occasions. Primary outcome was reduction in pain with each intervention. Results: There were 32 patients aged 46.44 ± 11.58 years. Pain intensity was 6.69 ± 0.58, 3.13 ± 1.28, and 4.55 ± 1.95 without any medication, prilocaine/lidocaine cream and piroxicam gel respectively. There was greater pain reduction with prilocaine/lidocaine cream than piroxicam gel (3.56 ± 1.35 vs 2.14 ± 1.78; Conclusion: Prilocaine/lidocaine cream provides better pain relief than piroxicam gel during arteriovenous fistula needling.
Language	English
Publishing date	2022-12-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/11297298221142375
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Control of SARS-CoV-2 infection in skilled nursing facilities in Detroit, Michigan: a model for emerging infectious diseases.

Joshi, Seema / Arshad, Samia / Lindsay, Abigail / Heinonen, Jessica / Misikir, Helina / Zervos, John / Prentiss, Tyler / Verkler, Jelena / Numi, Mariia / Czander, Bonnie / David, Randy E / Mossing, Michael / Kilgore, Paul E / Rehman, Najibah / Zervos, Marcus

Infection control and hospital epidemiology

2024 , Page(s) 1–3

Abstract: An infection prevention bundle that consisted of the development of a response team, public-academic partnership, daily assessment, regular testing, isolation, and environmental controls was implemented in 26 skilled nursing facilities in Detroit, ... ...

Abstract	An infection prevention bundle that consisted of the development of a response team, public-academic partnership, daily assessment, regular testing, isolation, and environmental controls was implemented in 26 skilled nursing facilities in Detroit, Michigan (March 2020-April 2021). This intervention was associated with sustained control of severe acute respiratory coronavirus virus 2 infection among residents and staff.
Language	English
Publishing date	2024-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	639378-0
ISSN	1559-6834 ; 0195-9417 ; 0899-823X
ISSN (online)	1559-6834
ISSN	0195-9417 ; 0899-823X
DOI	10.1017/ice.2024.35
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Article: Exploring the Relationship of Comorbidities, Smoking Status, HRCT Findings With COVID-19 Disease Severity and Outcomes.

Khan Raja, Sohail / Rafique Shiekh, Rubina / Arshad Abbasi, Mohammad Ali / Tariq, Samia / Saleem, Humayun / Tariq, Maham / Akbar, Amna / Jadoon, Sarosh Khan / Tasneem, Sabahat / Saleem Khan, Mohammad

Cureus

2024 Volume 16, Issue 1, Page(s) e52937

Abstract: Introduction: Coronavirus disease 2019 (COVID-19) is a serious illness that can affect multiple organs including the lungs. The COVID-mortality risk is attributed to the quick transmission of the virus, the severity of disease, and preclinical risk ... ...

Abstract	Introduction: Coronavirus disease 2019 (COVID-19) is a serious illness that can affect multiple organs including the lungs. The COVID-mortality risk is attributed to the quick transmission of the virus, the severity of disease, and preclinical risk factors, such as the presence of comorbidities. High-resolution computed tomography (HRCT) can predict disease severity in COVID-19 patients. Methodology: This was a retrospective cohort study in which data were obtained from COVID centers at tertiary care hospitals in Azad Jammu and Kashmir. Details of clinical characteristics and HRCT findings along with details of smoking and comorbid history were obtained. Results: Fever at hospital admission, HRCT findings, and having a partner predicted disease severity showed a significant p-value of <0.05. Old age and living in a combined household were associated with severe outcomes (p<0.05). Symptoms of shortness of breath (SOB) on hospital admission could predict the need for ICU admission in COVID-19 patients. Conclusion: HRCT has a good predictive value for disease severity in patients with COVID-19, and old age is a risk factor. Although, limited associations were established in the analysis, in this study hyperlipidemia and hypertension significantly affected the course of disease. Further studies should be done to explore the relationship.
Language	English
Publishing date	2024-01-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.52937
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Synergistic antibacterial activity of surfactant free Ag-GO nanocomposites.

Ahmad, Muhammad Ashfaq / Aslam, Samia / Mustafa, Faiza / Arshad, Usman

Scientific reports

2021 Volume 11, Issue 1, Page(s) 196

Abstract: Graphene oxide-silver (Ag-GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag-GO nanocomposite formation excluding the aid of surfactants and reductants and was successfully ... ...

Abstract	Graphene oxide-silver (Ag-GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag-GO nanocomposite formation excluding the aid of surfactants and reductants and was successfully applied to negative Escherichia Coli (E coli) to investigate antibacterial activity by varying doze concentration. The successful formation of Ag-GO nanocomposite via facile one step route was confirmed using Fourier transform infrared spectroscopy (FTIR) and Raman Spectroscopy. The absorption spectra (peak ~ 300 nm) for GO and the (peak ~ 420 nm) for silver nanoparticles were observed. XRD study confirmed the formation of Ag-GO nanocomposite while atomic force microscopy (AFM) showed crumbled GO sheets decorated with Ag nanoparticles. It was observed that the functional groups of GO facilitated the binding of Ag nanoparticles to GO network and enhanced the antibacterial activity of the nanocomposite.
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Escherichia coli/drug effects ; Graphite/chemistry ; Metal Nanoparticles/chemistry ; Nanocomposites/chemistry ; Silver/chemistry ; Silver/pharmacology ; Staphylococcus aureus/drug effects ; Surface-Active Agents/chemistry
Chemical Substances	Anti-Bacterial Agents ; Surface-Active Agents ; graphene oxide ; Silver (3M4G523W1G) ; Graphite (7782-42-5)
Language	English
Publishing date	2021-01-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-020-80013-w
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Article ; Online: Remote Sensing for Precise Nutrient Management in Agriculture

Tayyaba Samreen / Sidra Tahir / Samia Arshad / Sehrish Kanwal / Faraz Anjum / Muhammad Zulqernain Nazir / Sidra-Tul-Muntaha

Environmental Sciences Proceedings, Vol 23, Iss 32, p

2023 Volume 32

Abstract: Agricultural sustainability and food security are adversely affected by nutrient deficiency in the soil that in turn reduces crop yield. To restore soil fertility, precision agriculture (PA) techniques are highly encouraged. The PA techniques include the ...

Abstract	Agricultural sustainability and food security are adversely affected by nutrient deficiency in the soil that in turn reduces crop yield. To restore soil fertility, precision agriculture (PA) techniques are highly encouraged. The PA techniques include the use of integrated sensors, information systems, better-quality machinery, and informed management to improve productivity. The quality and quantity of agricultural products can be improved by precision farming. The use of remote sensing is a nondestructive technique that facilitates the application of PA. The nutrient use efficiency of crops can be improved by using PA technology. In this regard, various remote sensing techniques including hyperspectral remote sensing, visible light remote sensing, and the back-propagation neural network (BPNN) model combined with ordinary kriging (OK) known as BPNKOK are currently being employed to improve soil nutrients management. These techniques assist in non-destructive monitoring of plant growth and hence aid in sustaining crop yields.
Keywords	precision agriculture ; remote sensing ; nutrient management ; soil fertility ; Environmental sciences ; GE1-350
Subject code	630
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Synergistic antibacterial activity of surfactant free Ag–GO nanocomposites

Muhammad Ashfaq Ahmad / Samia Aslam / Faiza Mustafa / Usman Arshad

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 9

Abstract: Abstract Graphene oxide–silver (Ag–GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag–GO nanocomposite formation excluding the aid of surfactants and reductants and was ... ...

Abstract	Abstract Graphene oxide–silver (Ag–GO) nanocomposite has emerged as a vital antibacterial agent very recently. In this work, we report a facile one step route of Ag–GO nanocomposite formation excluding the aid of surfactants and reductants and was successfully applied to negative Escherichia Coli (E coli) to investigate antibacterial activity by varying doze concentration. The successful formation of Ag–GO nanocomposite via facile one step route was confirmed using Fourier transform infrared spectroscopy (FTIR) and Raman Spectroscopy. The absorption spectra (peak ~ 300 nm) for GO and the (peak ~ 420 nm) for silver nanoparticles were observed. XRD study confirmed the formation of Ag–GO nanocomposite while atomic force microscopy (AFM) showed crumbled GO sheets decorated with Ag nanoparticles. It was observed that the functional groups of GO facilitated the binding of Ag nanoparticles to GO network and enhanced the antibacterial activity of the nanocomposite.
Keywords	Medicine ; R ; Science ; Q
Subject code	540
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Managing Butterfly Career Attitudes

Muhammad Latif Khan / Rohani Salleh / Muhammad Umair Javaid / Muhammad Zulqarnain Arshad / Muhammad Shoaib Saleem / Samia Younas

Sustainability, Vol 15, Iss 5099, p

The Moderating Interplay of Organisational Career Management

2023 Volume 5099

Abstract: A protean career attitude is the most attractive and coping career adjustment attitude nowadays. Based on the social exchange theory, this study empirically analyses the association between protean career attitude and affective organisational commitment ... ...

Abstract	A protean career attitude is the most attractive and coping career adjustment attitude nowadays. Based on the social exchange theory, this study empirically analyses the association between protean career attitude and affective organisational commitment for Malaysian hotel industry employees. It also examines the COVID-19 situation’s retrospective repercussions and career uncertainty. The study also investigates the moderating role of organisational career management on the relationship between protean career attitudes and affective organisational commitment. During the pandemic, a cross-sectional survey was given to 403 hotel managers working in four- or five-star hotels. The data were analysed using structural equation modelling in Smart-PLS. The results showed that self-directed and value-driven protean career attitudes undermine affective organisational commitment. Organisational career management significantly moderated the relationship between a protean career attitude and affective organisational commitment. In light of this, organisational career management is essential when dealing with protean careers. Lastly, the person’s practical implications are significant. People should have a protean career attitude to deal with unpredictability, such as the COVID-19 epidemic and remain invincible over the long run.
Keywords	COVID-19 ; protean career attitude ; organisational career management ; affective organisational commitment ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	300
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: In Vitro Biofilm-Mediated Biodegradation of Pesticides and Dye-Contaminated Effluents Using Bacterial Biofilms.

Liaqat, Iram / Khalid, Awais / Rubab, Saima / Rashid, Farzana / Latif, Asma Abdul / Naseem, Sajida / Bibi, Asia / Khan, Bushra Nisar / Ansar, Waiza / Javed, Arshad / Afzaal, Muhammad / Summer, Muhammad / Majid, Samia / Ali, Sikander / Aftab, Muhammad Nauman

Microorganisms

2023 Volume 11, Issue 9

Abstract: Overuse of pesticides in agricultural soil and dye-polluted effluents severely contaminates the environment and is toxic to animals and humans making their removal from the environment essential. The present study aimed to assess the biodegradation of ... ...

Abstract	Overuse of pesticides in agricultural soil and dye-polluted effluents severely contaminates the environment and is toxic to animals and humans making their removal from the environment essential. The present study aimed to assess the biodegradation of pesticides (cypermethrin (CYP) and imidacloprid (IMI)), and dyes (malachite green (MG) and Congo red (CR)) using biofilms of bacteria isolated from pesticide-contaminated soil and dye effluents. Biofilms of indigenous bacteria, i.e.,
Language	English
Publishing date	2023-08-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11092163
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Article ; Online: Efficacy of Chemotherapy for Locally Advanced and Metastatic Pancreatic Cancer: A Real-life Experience and Outcome from a Tertiary Care Centre.

Yasmeen, Samia / Arshad, Farah / Shaukat, Sabah / Badar, Farhana / Kazmi, Syed Ather Saeed / Ahmad, Usman

Journal of cancer & allied specialties

2021 Volume 7, Issue 2, Page(s) e409

Abstract: Introduction: To report response rates, progression-free survival (PFS) and overall survival (OS) in patients with advanced pancreatic cancer treated with different available chemotherapeutic regimens over 10 years.: Materials and methods: This is a ... ...

Abstract	Introduction: To report response rates, progression-free survival (PFS) and overall survival (OS) in patients with advanced pancreatic cancer treated with different available chemotherapeutic regimens over 10 years. Materials and methods: This is a retrospective observational study. All patients with locally advanced and metastatic pancreatic cancer (MPC) at Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, from January 2008 to December 2017 were studied. Data were collected from the hospital information system. The characteristics and outcomes of all the patients were analysed. PFS and OS were also estimated. Kaplan-Meier curves and log-rank test were applied, and SPSS version 20 was used for data analysis. Results: Eighty-seven subjects with a median age of 56 years (range 21-76) were included. Sixty-two (71%) subjects were male. The most common tumour location was the head of the pancreas in 46 (53%) of all the subjects. Sixty-three (72%) subjects had elevated carbohydrate antigen-19.9 values. About 47 (54%) subjects had locally advanced pancreatic cancer (LAPC), and 40 (46%) subjects had MPC. Chemotherapy regimens used were FOLFIRINOX in 23 (26%), gemcitabine (GEM) based in 66 (65%) and capecitabine (CAP) based in 8 (9%) of the subjects. One (1%) subject had a complete response, 12 (14%) had a partial response, 10 (11%) had stable disease and 59 (68%) of the subjects had progressive disease. The objective response rate (ORR) was 15% and the disease control rate (DCR) was 26%. In MPC, the ORR was 10%, DCR was 18% and tumour progression was seen in 72% of the patients, while in LAPC, the ORR was 19.1, DCR 34% and tumour progression was documented in 64% of the patients, respectively. The FOLFIRINOX chemotherapy regimen had better ORR, DCR and lesser number of progressions as compared to GEM- and CAP-based chemotherapy regimens. The median PFS of the whole group was 32 weeks, and the median OS was 54 weeks. The PFS was significantly higher for LAPC (39 weeks) as compared to the MPC group (25 weeks) ( Conclusion: Based on our results, FOLFIRINOX remained the most effective chemotherapy regimen despite the dose modifications and toxicities in all groups, indicating that modified FOLFIRINOX could be considered as a first-line regimen in Southeast Asian population.
Language	English
Publishing date	2021-05-31
Publishing country	Pakistan
Document type	Journal Article
ISSN	2411-989X
ISSN (online)	2411-989X
DOI	10.37029/jcas.v7i2.409
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Article: Assessment of neuropharmacological consequences induced by dexamethasone administration in rats model of neurodegenerative diseases.

Farhan, Muhammad / Khan, Samia / Ahmed Soomro, Ayesha / Ahmed, Shoaib / Bibi, Anila / Rabab Zehra, Syeda / Arshad, Maria / Riaz, Fatima / Rehman, Sadia / Asif, Saher

Pakistan journal of pharmaceutical sciences

2023 Volume 36, Issue 6, Page(s) 1735–1741

Abstract: Stress is a well-known and frequently used term among present generation. It has been referred to the response of body to any challenge for a change. It is a natural process and our body is designed to cope with it. However, if stress becomes chronic, it ...

Abstract	Stress is a well-known and frequently used term among present generation. It has been referred to the response of body to any challenge for a change. It is a natural process and our body is designed to cope with it. However, if stress becomes chronic, it can lead to mental health problems. Stress due to the prolonged administration of glucocorticoid is enabled to produce impressive alterations in rats model shoeing depressive like behavior. In this investigation; purpose was to study the impact of episodic treatment of dexamethasone with respect to behavioral changes in rats. It was hypothesized that repeated administration of dexamethasone could increase stress and thus, psychological stress leading to mood disorders and behavior deficits in rats. Rats were injected daily with DEX (10 mg/ml/kg, orally) and the different behavioral models of the animals were assessed. DEX-treated rats exhibited depressive behavior like greater time to start mobility in a novel environment and elevated anxiety-like behavior in elevated plus maze. However, time spent in light compartment was shorter with repeated administration of DEX. From results it is demonstrated that the administration of DXM for weeks induced stress and consequently, induced a depression-like behaviors in rats models.
MeSH term(s)	Rats ; Animals ; Dexamethasone/pharmacology ; Neurodegenerative Diseases ; Glucocorticoids/pharmacology ; Depression/chemically induced ; Depression/drug therapy ; Anxiety ; Behavior, Animal ; Stress, Psychological
Chemical Substances	Dexamethasone (7S5I7G3JQL) ; Glucocorticoids
Language	English
Publishing date	2023-12-20
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
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