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  1. Article: Retraction: The Association of Serum Ferritin Levels With Non-scarring Alopecia in Women.

    Aslam, Muhammad Fawad / Khalid, Mariam / Amad Aslam, Muhammad

    Cureus

    2024  Volume 16, Issue 2, Page(s) r136

    Abstract: This retracts the article DOI: 10.7759/cureus.32123.]. ...

    Abstract [This retracts the article DOI: 10.7759/cureus.32123.].
    Language English
    Publishing date 2024-02-06
    Publishing country United States
    Document type Retraction of Publication
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.r136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Systematic Review of the Economic Burden of Diabetes in Eastern Mediterranean Region Countries.

    Arshad, Muhammad Subhan / Alqahtani, Faleh / Rasool, Muhammad Fawad

    Diabetes, metabolic syndrome and obesity : targets and therapy

    2024  Volume 17, Page(s) 479–487

    Abstract: Diabetes Mellitus (DM) is a highly prevalent non-communicable disease with high mortality and morbidity, which imposes a significant financial impact on individuals and the healthcare system. The identification of various cost components through cost of ... ...

    Abstract Diabetes Mellitus (DM) is a highly prevalent non-communicable disease with high mortality and morbidity, which imposes a significant financial impact on individuals and the healthcare system. The identification of various cost components through cost of illness analysis could be helpful in health-care policymaking. The current systematic review aims to summarize the economic burden of DM in the Eastern Mediterranean Region (EMR) countries. The original studies published in the English language between January 2010 and June 2023 reported the cost of DM was identified by searching four different databases (Google Scholar, PubMed, Science Direct, and Cochrane Central). Two reviewers independently screened the search results and extracted the data according to a predefined format, whereas the third reviewer's opinion was sought to resolve any discrepancies. The costs of DM reported in the included studies were converted to USD dates reported in the studies. After the systematic search and screening process, only 10 articles from EMR countries met the eligibility criteria to be included in the study. There are substantial variations in the reported costs of DM and the methodologies used in the included studies. The mean annual cost per patient of DM (both direct and indirect cost) ranged from 555.20 USD to 1707.40 USD. The average annual direct cost ranged from 155.8 USD to 5200 USD and indirect cost ranged from 93.65 USD to 864.8 USD per patient. The studies included in the review obtained a median score of 8.65 (6.5 ─ 11.5) on the quality assessment tool based on Alison's checklist for evaluation of cost of illness studies. There is a significant economic burden associated with DM, which directly affects the patients and healthcare system. Future research should focus on refining cost estimation methodologies, improving the understanding of study findings, and making it easier to compare studies.
    Language English
    Publishing date 2024-02-01
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2494854-8
    ISSN 1178-7007
    ISSN 1178-7007
    DOI 10.2147/DMSO.S440282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Predictive Ability of LRINEC Score for Lower Extremity Amputation in Moderate to Severe Diabetic Foot Infection.

    Hameed, Abdul / Khan, Shahid Mehmood / Khalil, Muhammad Tawab / Tariq, Ahmed / Fawad, Muhammad / Leghari, Muhammad Ajmal

    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP

    2024  Volume 34, Issue 4, Page(s) 456–460

    Abstract: Objective: To assess the predictive ability of the laboratory risk indicator for necrotising fasciitis (LRINEC) score for lower extremity amputation in patients with moderate to severe diabetic foot infection (DFI).: Study design: Observational study. ...

    Abstract Objective: To assess the predictive ability of the laboratory risk indicator for necrotising fasciitis (LRINEC) score for lower extremity amputation in patients with moderate to severe diabetic foot infection (DFI).
    Study design: Observational study. Place and Duration of the Study: Department of General Surgery, Combined Military Hospital, Rawalpindi, Pakistan, from June to September 2023.
    Methodology: Patients admitted to the surgical ward with moderate to severe DFI were included by convenience sampling. Patients with severe sepsis, unstable haemodynamics, pressure injuries, and terminal illnesses were excluded. Demographic and clinical data of patients were noted down. LRINEC score was calculated on the day of admission. Final outcome (amputation or otherwise) was recorded on the 30th day the since the day of admission.
    Results: Two hundred patients with moderate to severe DFI were included. The median age of patients was 56 years (IQR 49-66 years). The median duration of diabetes was 11 years (IQR 4 - 18.75 years). The median LRINEC score at admission was 6 (IQR 3-9). The majority of the patients (65.5%) had some other medical comorbid besides diabetes. Patients who had amputation due to DFI at 30 days post-admission had higher LRINEC scores on admission as compared to those patients who did not have amputation (Median 8 vs. 2, p <0.001). The cut-off point of LRINEC score ≥6.5 at admission had sensitivity of 74% and specificity of 94% in predicting amputation.
    Conclusion: The LRINEC score may be used as an objective scoring system to predict the risk of amputation in patients with moderate to severe DFI in indoor clinical settings.
    Key words: Diabetic foot, LRINEC score, Limb loss, Necrotising fasciitis.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Fasciitis, Necrotizing/surgery ; Diabetic Foot/surgery ; Retrospective Studies ; Risk Factors ; Skin Diseases ; Amputation, Surgical ; Lower Extremity/surgery ; Diabetes Mellitus
    Language English
    Publishing date 2024-04-05
    Publishing country Pakistan
    Document type Observational Study ; Journal Article
    ZDB-ID 2276646-7
    ISSN 1681-7168 ; 1022-386X
    ISSN (online) 1681-7168
    ISSN 1022-386X
    DOI 10.29271/jcpsp.2024.04.456
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Impact of Irrigation Timing and Weed Management Practices on Chlorophyll Content and Morphological Traits of Tomato (Solanum lycopersicum Mill.)

    Fawad, Muhammad / Khan, Muhammad Azim

    Gesunde Pflanzen. 2022 June, v. 74, no. 2

    2022  

    Abstract: Weeds are a major biotic constraint; compete with crop for the same resources and ultimately reduce productivity. This study evaluated the impact of irrigation intervals and weed management treatments on chlorophyll content and morphological growth of ... ...

    Title translation Auswirkung des Bewässerungszeitpunkts und der Unkrautbekämpfungsmaßnahmen auf den Chlorophyllgehalt und die morphologischen Eigenschaften der Tomate (Solanum lycopersicum Mill.)
    Abstract Weeds are a major biotic constraint; compete with crop for the same resources and ultimately reduce productivity. This study evaluated the impact of irrigation intervals and weed management treatments on chlorophyll content and morphological growth of tomato to find an appropriate integrated weed management strategy. Two-year field experiments (2018/2019) were conducted at district Mardan (34°15′38″ N and 72°6′36″ E). Tomato F1 hybrid (Taj‑3592) was transplanted during March. The experiments were laid out in a randomized complete-block design in split-plot arrangement with three replications. The main block comprised three irrigation intervals (3, 6, and 9 days) and the sub-block included weed management treatments: transparent polythene, black polythene, weeding except Orobanche, sole weeding of Orobanche, weeding of all weeds, copper oxychloride 1.5 kg a.i ha⁻¹ (single dose), copper oxychloride 1.5 kg a.i ha⁻¹ (split doses), copper oxychloride + humic acid 25 kg ha⁻¹ (single dose), copper oxychloride + humic acid 25 kg ha⁻¹ (split doses), copper sulphate 2 kg ha⁻¹ (single dose), copper sulphate 2 kg ha⁻¹ (split doses), ammonium sulphate 200 kg ha⁻¹ (single dose), ammonium sulphate 200 kg ha⁻¹ (split doses), pendimethalin 33 EC 1.44 kg a.i ha⁻¹, glyphosate 48 SL 1.5 kg a.i ha⁻¹, and weedy check. Lowest relative weed density (RWD) of O. cernua (2.23%) and highest RWD of O. cernua (38.01%) were recorded in the 3‑ and 9‑day irrigation intervals, respectively. However, 3‑day irrigation interval resulted in highest fresh weed biomass (5794 kg ha⁻¹). Moreover, the 6‑day irrigation interval significantly increased chlorophyll content by 11 and 5%, leaf area by 23 and 6%, and number of branches plant⁻¹ by 30 and 22% compared to 9‑ and 3‑day irrigation intervals, respectively. Among the weed management treatments, black polythene resulted in the highest weed control efficiency (96%), increasing chlorophyll content by 16%, leaf area by 33%, and number of branches plant⁻¹ by 64% vs. weedy check. Consequently, 6‑day irrigation intervals × black polythene could be the best weed management strategy, followed by transparent polythene, weeding of all weeds, pendimethalin, glyphosate, and ammonium sulphate.
    Keywords Solanum lycopersicum ; ammonium sulfate ; biomass ; chlorophyll ; copper oxychloride ; copper sulfate ; glyphosate ; humic acids ; integrated weed management ; irrigation scheduling ; leaf area ; pendimethalin ; tomatoes ; weeds
    Language English
    Dates of publication 2022-06
    Size p. 317-332.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 820036-1
    ISSN 1439-0345 ; 0367-4223
    ISSN (online) 1439-0345
    ISSN 0367-4223
    DOI 10.1007/s10343-021-00611-0
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Forecasting the strength of preplaced aggregate concrete using interpretable machine learning approaches.

    Javed, Muhammad Faisal / Fawad, Muhammad / Lodhi, Rida / Najeh, Taoufik / Gamil, Yaser

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8381

    Abstract: Preplaced aggregate concrete (PAC) also known as two-stage concrete (TSC) is widely used in construction engineering for various applications. To produce PAC, a mixture of Portland cement, sand, and admixtures is injected into a mold subsequent to the ... ...

    Abstract Preplaced aggregate concrete (PAC) also known as two-stage concrete (TSC) is widely used in construction engineering for various applications. To produce PAC, a mixture of Portland cement, sand, and admixtures is injected into a mold subsequent to the deposition of coarse aggregate. This process complicates the prediction of compressive strength (CS), demanding thorough investigation. Consequently, the emphasis of this study is on enhancing the comprehension of PAC compressive strength using machine learning models. Thirteen models are evaluated with 261 data points and eleven input variables. The result depicts that xgboost demonstrates exceptional accuracy with a correlation coefficient of 0.9791 and a normalized coefficient of determination (R
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-57896-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Boosting-based ensemble machine learning models for predicting unconfined compressive strength of geopolymer stabilized clayey soil.

    Abdullah, Gamil M S / Ahmad, Mahmood / Babur, Muhammad / Badshah, Muhammad Usman / Al-Mansob, Ramez A / Gamil, Yaser / Fawad, Muhammad

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2323

    Abstract: The present research employs new boosting-based ensemble machine learning models i.e., gradient boosting (GB) and adaptive boosting (AdaBoost) to predict the unconfined compressive strength (UCS) of geopolymer stabilized clayey soil. The GB and AdaBoost ... ...

    Abstract The present research employs new boosting-based ensemble machine learning models i.e., gradient boosting (GB) and adaptive boosting (AdaBoost) to predict the unconfined compressive strength (UCS) of geopolymer stabilized clayey soil. The GB and AdaBoost models were developed and validated using 270 clayey soil samples stabilized with geopolymer, with ground-granulated blast-furnace slag and fly ash as source materials and sodium hydroxide solution as alkali activator. The database was randomly divided into training (80%) and testing (20%) sets for model development and validation. Several performance metrics, including coefficient of determination (R
    Language English
    Publishing date 2024-01-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-52825-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Optic Disc Pit Associated With Choroidal Coloboma: Case Report And Short Review.

    Jamil, Muhammad Usman / Mahmood, Aysal / Rizvi, Syed Fawad

    Journal of Ayub Medical College, Abbottabad : JAMC

    2024  Volume 35, Issue 3, Page(s) 507–509

    Abstract: Optic disc pits are hypothesized to form because of failure of embryonic fissure closure, which can also present with congenital defects in the choroid, RPE, and neurosensory retina. It is also associated with serous macular detachment. We present a case ...

    Abstract Optic disc pits are hypothesized to form because of failure of embryonic fissure closure, which can also present with congenital defects in the choroid, RPE, and neurosensory retina. It is also associated with serous macular detachment. We present a case report of a 32-year-old man with an optic disc pit and independent choroidal coloboma below the inferior peripapillary area in the left eye, associated with macular retinoschisis with serous detachment.
    MeSH term(s) Adult ; Humans ; Male ; Coloboma/complications ; Coloboma/diagnosis ; Eye Abnormalities/complications ; Optic Disk ; Retinal Detachment/etiology ; Retinal Detachment/complications ; Retinoschisis/complications ; Retinoschisis/diagnosis
    Language English
    Publishing date 2024-02-25
    Publishing country Pakistan
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2192473-9
    ISSN 1819-2718 ; 1025-9589
    ISSN (online) 1819-2718
    ISSN 1025-9589
    DOI 10.55519/JAMC-03-11574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Chronic kidney disease and physiologically based pharmacokinetic modeling: a critical review of existing models.

    Zamir, Ammara / Alqahtani, Faleh / Rasool, Muhammad Fawad

    Expert opinion on drug metabolism & toxicology

    2024  Volume 20, Issue 1-2, Page(s) 95–105

    Abstract: Introduction: Physiologically based pharmacokinetic (PBPK) modeling is a paradigm shift in this era for determining the exposure of drugs in pediatrics, geriatrics, and patients with chronic diseases where clinical trials are difficult to conduct.: ... ...

    Abstract Introduction: Physiologically based pharmacokinetic (PBPK) modeling is a paradigm shift in this era for determining the exposure of drugs in pediatrics, geriatrics, and patients with chronic diseases where clinical trials are difficult to conduct.
    Areas covered: This review has collated data regarding published PBPK models on chronic kidney disease (CKD), including the drug and system-specific input model parameters and model evaluation criteria. Four databases were used from 13th June 2023 to 10
    Expert opinion: This review will provide insights for researchers on applying PBPK models in managing patients with different levels of CKD to prevent undesirable side effects and increase the effectiveness of drug therapy.
    MeSH term(s) Humans ; Child ; Models, Biological ; Renal Insufficiency, Chronic ; Computer Simulation ; Glomerular Filtration Rate
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2214462-6
    ISSN 1744-7607 ; 1742-5255
    ISSN (online) 1744-7607
    ISSN 1742-5255
    DOI 10.1080/17425255.2024.2311154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A hybrid heuristic-driven technique to study the dynamics of savanna ecosystem

    Khan, Muhammad Fawad / Sulaiman, Muhammad / Alshammari, Fahad Sameer

    Stoch Environ Res Risk Assess. 2023 Jan., v. 37, no. 1 p.1-25

    2023  

    Abstract: Savanna fire has many types: Savanna woody, Savanna vegetation, and grassland. In this paper, Savanna vegetation is studied, characterized by low trees and high grass. It grows in hot and seasonally dry conditions. The Savanna vegetation is described by ... ...

    Abstract Savanna fire has many types: Savanna woody, Savanna vegetation, and grassland. In this paper, Savanna vegetation is studied, characterized by low trees and high grass. It grows in hot and seasonally dry conditions. The Savanna vegetation is described by relating to the environment and climate. Savanna vegetation is considered a metastable mixture of trees and grass and is advanced to explain stability. The Savanna vegetation is modeled with first-order linear differential equations having grass, trees, and sapling (young trees) as components. Furthermore, the model is evaluated numerically by integrating the global search technique Sine-Cosine algorithm and local search technique Interior point algorithm. Comprehensive numerical experiments are conducted to analyze numerical results. To validate solution of proposed technique, Runge-Kutta order four method isolution is taken as a reference solution. The solutions are compared graphically with the results of the reference technique. Performance indicators Mean Absolute Deviation, Root Mean Squared Error, and Error in Nash-Sutcliffe Efficiency are implemented to verify consistency, and multiple independent runs are drawn. Furthermore, the scheme is evaluated through convergence graphs as well.
    Keywords algorithms ; climate ; ecosystems ; grasses ; grasslands ; hybrids ; models ; risk ; savannas
    Language English
    Dates of publication 2023-01
    Size p. 1-25.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1481263-0
    ISSN 1436-3259 ; 1435-151X ; 1436-3240 ; 0931-1955
    ISSN (online) 1436-3259 ; 1435-151X
    ISSN 1436-3240 ; 0931-1955
    DOI 10.1007/s00477-022-02270-7
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Relation of poverty with treatment-seeking behavior and antibiotic misuse among UTI patients in Pakistan.

    Hussain, Iltaf / Shukar, Sundus / Subhan Arshad, Muhammad / Rasool, Muhammad Fawad / Chang, Jie / Fang, Yu

    Frontiers in public health

    2024  Volume 12, Page(s) 1357107

    Abstract: Objective: The current study aimed to assess the relation between multi-dimension poverty, treatment-seeking behavior, and antibiotic misuse among urinary tract infection (UTI) patients.: Method: A cross-sectional approach was utilized to recruit ... ...

    Abstract Objective: The current study aimed to assess the relation between multi-dimension poverty, treatment-seeking behavior, and antibiotic misuse among urinary tract infection (UTI) patients.
    Method: A cross-sectional approach was utilized to recruit patients who had a history of UTI in the previous month from two provinces of Pakistan. The treatment-seeking behavior and antibiotic misuse data were collected on a self-developed questionnaire, whereas the poverty data were collected on a modified multi-dimension poverty index (MPI). Descriptive statistics were applied to summarize the data. The logistic regression analysis was carried out to assess the association of multi-dimension poverty with patient treatment-seeking behavior and antibiotic misuse.
    Results: A total of 461 participants who had UTI symptoms in the previous month were recruited. Most of the participants in the severely deprived stage treated the UTI (
    Conclusion: The current study highlighted that poverty plays an important role in antibiotic misuse. Poorer subgroups were associated with informal consultations and the incompletion of the antibiotic course. Further studies are needed to explore the potential role of poverty in treatment-seeking behavior and antibiotic misuse.
    MeSH term(s) Humans ; Anti-Bacterial Agents/therapeutic use ; Pakistan/epidemiology ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/epidemiology ; Urinary Tract Infections/diagnosis ; Surveys and Questionnaires ; Poverty
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-03-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1357107
    Database MEDical Literature Analysis and Retrieval System OnLINE

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