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Article ; Online: Sustainable Environmental Economics in Farmers’ Production Factors via Irrigation Resources Utilization Using Technical Efficiency and Allocative Efficiency

Michel Mivumbi / Xiaoling Yuan

Sustainability, Vol 15, Iss 4101, p

2023 Volume 4101

Abstract: This study reports the results of farmers’ production via irrigation resources utilization and efficiency parameters of technical efficiency and allocative efficiency by way of sustainable environmental economics. The hypothesis is that factors of ... ...

Abstract	This study reports the results of farmers’ production via irrigation resources utilization and efficiency parameters of technical efficiency and allocative efficiency by way of sustainable environmental economics. The hypothesis is that factors of farmers’ production affect technical efficiency and allocative efficiency in the irrigation scheme as sustainable environmental economics. Data from cross section and panel data were used and then the productivity parameters measurement of the production function are outlined in two scenarios: first, the data report that the parameters such as output elasticity determine factors of inefficiency and technical efficiency. Second, it presents the scores for the allocative efficiency to explain whether production factors (resources) are optimally, under- or over-allocated by farmers in the irrigation systems under environmental sustainability. This paper presents the productivity and efficiency parameters estimated using stochastic frontier analysis for the translog production function, which was estimated by the MLE method, and the allocative efficiency for the factor inputs allocation in the irrigation systems estimated by ordinary least square for the Cobb-Douglas production function. This study concludes that collective farmers lead into technical inefficiency and over use of factors of production.
Keywords	sustainable environment ; irrigation ; allocative efficient ; technical efficient ; elasticities ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	338
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Virulence Factors and Carbapenem-Resistance Mechanisms in Hypervirulent

Liao, Yiqun / Gong, Junjie / Yuan, Xiaoliang / Wang, Xiaoling / Huang, Yuanhong / Chen, Xiaohong

Infection and drug resistance

2024 Volume 17, Page(s) 1551–1559

Abstract: ... ...

Abstract	Hypervirulent
Language	English
Publishing date	2024-04-20
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2494856-1
ISSN	1178-6973
ISSN	1178-6973
DOI	10.2147/IDR.S461903
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Article ; Online: miR-155-5p promotes hepatic steatosis via PICALM-mediated autophagy in aging hepatocytes.

Chen, Xiaoling / Lu, Ting / Zheng, Ying / Lin, Zhiyong / Liu, Chaoqi / Yuan, Ding / Yuan, Chengfu

Archives of gerontology and geriatrics

2024 Volume 120, Page(s) 105327

Abstract: Background: Hepatic steatosis, a lipid disorder characterized by the accumulation of intrahepatic fat, is more prevalent in the elderly population. This study investigates the role of miR-155-5p in the autophagy dysregulation of aging hepatic steatosis.! ...

Abstract	Background: Hepatic steatosis, a lipid disorder characterized by the accumulation of intrahepatic fat, is more prevalent in the elderly population. This study investigates the role of miR-155-5p in the autophagy dysregulation of aging hepatic steatosis. Methods: We established an aging mouse model in vivo and a hepatocellular senescence model induced by low serum and palmitic acid in vitro. The fluctuations of microRNAs were derived from RNA-seq data and confirmed by qPCR in 4- and 18-month-old mouse liver tissues. Hematoxylin-eosin (H&E) staining observed pathological changes. Markers of senescence, autophagy, and lipolysis genes were analyzed using Western blot and qPCR. Bioinformatics analysis predicted miR-155-5p's target gene PICALM, confirmed by dual luciferase reporter assay and transfection of miR-155-5p mimic/inhibitor into senescent hepatocytes. Results: Senescent markers (p21, p16, and p-P53) and miR-155-5p were up-regulated in aging liver tissues and senescent hepatocytes. Bioinformatics analysis identified PICALM as a target gene of miR-155-5p, a finding further supported by dual luciferase reporter assays. Inhibition of miR-155-5p reduced expression of senescent marker genes (p16, p21, p-P53), improved autophagy (evidenced by increased LC3B-II and ATG5, and decreased P62), and enhanced lipolysis (indicated by increased ATGL and p-HSL) in senescent hepatocytes. Oil red O staining confirmed that miR-155-5p inhibition significantly reduced lipid accumulation in these cells. Conclusions: This study suggests a potential new therapeutic approach for age-related hepatic steatosis through the inhibition of miR-155-5p to enhance autophagy.
MeSH term(s)	Aged ; Mice ; Animals ; Humans ; Tumor Suppressor Protein p53/metabolism ; Hepatocytes/metabolism ; Hepatocytes/pathology ; MicroRNAs/genetics ; Aging ; Autophagy ; Luciferases/metabolism ; Lipids ; Monomeric Clathrin Assembly Proteins/metabolism
Chemical Substances	Tumor Suppressor Protein p53 ; MicroRNAs ; Luciferases (EC 1.13.12.-) ; Lipids ; PICALM protein, human ; Monomeric Clathrin Assembly Proteins ; MIRN155 microRNA, human ; Mirn155 microRNA, mouse
Language	English
Publishing date	2024-01-09
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	603162-6
ISSN	1872-6976 ; 0167-4943
ISSN (online)	1872-6976
ISSN	0167-4943
DOI	10.1016/j.archger.2024.105327
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Article: Enhancing the accumulation of linoleic acid and α-linolenic acid through the pre-harvest ethylene treatment in

Li, Hongbo / Ma, Xiaoling / Wang, Weiqi / Zhang, Jiaxi / Liu, Yuanzhe / Yuan, Deyi

Frontiers in plant science

2023 Volume 14, Page(s) 1080946

Abstract: ... Camellia ... ...

Abstract	Camellia oleifera
Language	English
Publishing date	2023-02-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1080946
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Article ; Online: Understanding the Antecedents and Effects of mHealth App Use in Pandemics: A Sequential Mixed-Method Investigation.

Jin, Xiaoling / Yuan, Zhangshuai / Zhou, Zhongyun

International journal of environmental research and public health

2023 Volume 20, Issue 1

Abstract: Pandemics such as COVID-19 pose serious threats to public health and disrupt the established systems for obtaining healthcare services. Mobile health (mHealth) apps serve the general public as a potential method for coping with these exogenous challenges. ...

Abstract	Pandemics such as COVID-19 pose serious threats to public health and disrupt the established systems for obtaining healthcare services. Mobile health (mHealth) apps serve the general public as a potential method for coping with these exogenous challenges. However, prior research has rarely discussed the antecedents and effects of mHealth apps and their use as a coping method during pandemics. Based on the technology acceptance model, empowerment theory, and event theory, we developed a research model to examine the antecedents (technology characteristics and event strength) and effects (psychological empowerment) of mHealth apps and their use. We tested this research model through a sequential mixed-method investigation. First, a quantitative study based on 402 Chinese mHealth users who used the apps during the COVID-19 pandemic was conducted to validate the theoretical model. A follow-up qualitative study of 191 online articles and reviews on mHealth during the COVID-19 pandemic was conducted to cross-validate the results and explain the unsupported findings of the quantitative study. The results show that (1) the mHealth app characteristics (perceived usefulness and perceived ease of use) positively affect mHealth app use; (2) mHealth app use positively affects the psychological empowerment of mHealth users; and (3) the characteristics of pandemic events (event criticality and event disruption) have positive moderating effects on the relationship between mHealth app characteristics and mHealth app use. This study explains the role of mHealth apps in the COVID-19 pandemic on the micro-level, which has implications for the ways in which mHealth apps are used in response to public pandemics.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Pandemics ; Mobile Applications ; Telemedicine/methods ; Confidentiality
Language	English
Publishing date	2023-01-02
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20010834
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Article ; Online: miR-743b-3p promotes hepatic lipogenesis via branched-chain amino acids (BCAA) metabolism by targeting PPM1K in aged mice.

Lu, Ting / Zheng, Ying / Chen, Xiaoling / Lin, Zhiyong / Liu, Chaoqi / Yuan, Chengfu

Archives of gerontology and geriatrics

2024 Volume 123, Page(s) 105424

Abstract: Background: Lipid metabolism disorders appear to play an important role in the ageing process, thus understanding the cellular and molecular mechanisms underlying the association of ageing with elevated vulnerability to lipid metabolism related diseases ...

Abstract	Background: Lipid metabolism disorders appear to play an important role in the ageing process, thus understanding the cellular and molecular mechanisms underlying the association of ageing with elevated vulnerability to lipid metabolism related diseases is crucial towards promoting quality of life in old age. MicroRNAs (miRNAs) have emerged as crucial regulators of lipid metabolism, and some miRNAs have key roles in ageing. Methods: In this study, we investigated changes in liver lipid metabolism of ageing mice and the mechanisms of the altered expression of miRNAs in the ageing liver which contributes to the age-dependent increase in lipid synthesis. Here we found that miR-743b-3p was higher expressed in the liver tissues of ageing mice through the small RNA sequencing and bioinformatics analysis, and its target PPM1K was predicted and confirmed the target relationship of miR-743b-3p with PPM1K in the aged mouse liver tissues and the cultured senescent hepatocytes in vitro. Moreover, using the transfected miR-743b-3p mimics/inhibitors into the senescent hepatocyte AML12. Results: We found that miR-743b-3p inhibition reversed the hepatocyte senescence, and finally decreased the expression of genes involved in lipid synthesis(Chrebp, Fabp4, Acly and Pparγ) through increasing the target gene expression of PPM1K which regulated the expression of branched-chain amino acids (BCAA) metabolism-related genes (Bckdhα, Bckdk, Bcat2, Dbt). Conclusions: These results identify that age-induced expression of miR-743b-3p inhibits its target PPM1K which induces BCAA metabolic disorder and regulates hepatocyte lipid accumulation during ageing.
Language	English
Publishing date	2024-03-26
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	603162-6
ISSN	1872-6976 ; 0167-4943
ISSN (online)	1872-6976
ISSN	0167-4943
DOI	10.1016/j.archger.2024.105424
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Article: Extracting Additional Influences From Physician Profiles With Topic Modeling: Impact on Ratings and Page Views in Online Healthcare Communities.

Wei, Xiaoling / Hsu, Yuan-Teng

Frontiers in psychology

2022 Volume 13, Page(s) 830841

Abstract: How physicians can get better ratings and more page views in online healthcare communities is an important issue. Based on 38,457 physicians' profiles from a popular online healthcare community in China, we used Latent Dirichlet Allocation model, which ... ...

Abstract	How physicians can get better ratings and more page views in online healthcare communities is an important issue. Based on 38,457 physicians' profiles from a popular online healthcare community in China, we used Latent Dirichlet Allocation model, which is a common topic model, to analyze the non-English text to obtain more doctor's latent characteristics. We found five of the most frequently mentioned topics. In addition to the first topic (doctor's academic rank and practice name), "research ability," "foreign experience," "committee position," and "clinical experience" were included as unstructured descriptions in the doctor's profile. Inferences about physician ratings and page views could be improved if these themes were set as characteristics of physicians. Specifically, in our findings, Physicians' mentions of their "research ability" and "foreign experience" had a significant positive impact on physician ratings. Surprisingly, physicians mentioning more "clinical experience" had a significant negative impact on physician ratings. Moreover, while descriptions about "foreign experience" and "committee position" had a significant positive impact on page views, physician mentions of "research ability" had a significant negative impact on page views. These results provide new insights into the ways in which online healthcare community managers or physicians create their personal online profiles.
Language	English
Publishing date	2022-04-01
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2563826-9
ISSN	1664-1078
ISSN	1664-1078
DOI	10.3389/fpsyg.2022.830841
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Article ; Online: Hepcidin contributes to largemouth bass (Micropterus salmoides) against bacterial infections.

Zhang, Weixiang / Li, Bo / Yu, Ruying / Xu, Wenyan / Liu, Xiaoling / Su, Jianguo / Yuan, Gailing

International journal of biological macromolecules

2024 Volume 266, Issue Pt 1, Page(s) 131144

Abstract: The increasing emergence and dissemination of bacterial pathogens in largemouth bass culture accelerate the desire for new treatment measures. Antimicrobial peptides as the host's antimicrobial source dominate the preferred molecules for discovering ... ...

Abstract	The increasing emergence and dissemination of bacterial pathogens in largemouth bass culture accelerate the desire for new treatment measures. Antimicrobial peptides as the host's antimicrobial source dominate the preferred molecules for discovering antibacterial agents. Here, the potential of Hepcidin-1 from largemouth bass (Micropterus salmoides) (MsHep-1) against bacterial infection is demonstrated. MsHep-1 not only improved the survival rate in infection experiments involving Nocardia seriolae (12 %) and Aeromonas hydrophila (18 %) but also coped with iron overload conditions in vivo. Moreover, the antibacterial activity of MsHep-1 in vitro was identified against both gram-negative and gram-positive bacteria. Mechanistic studies show MsHep-1 leads to bacterial death by changing the bacterial membrane potential and disrupting the bacterial membrane structure. These findings demonstrate that MsHep-1 may play an important role in the host response to bacterial infection. It provides promising strategies in the application of immunosuppression prevention and control in fish. AMPs may be a promising and available reservoir for treating the current bacterial diseases.
Language	English
Publishing date	2024-03-29
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2024.131144
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Article ; Online: Heterogeneous Feature Selection Based on Neighborhood Combination Entropy.

Zhang, Pengfei / Li, Tianrui / Yuan, Zhong / Luo, Chuan / Liu, Keyu / Yang, Xiaoling

IEEE transactions on neural networks and learning systems

2024 Volume 35, Issue 3, Page(s) 3514–3527

Abstract: Feature selection aims to remove irrelevant or redundant features and thereby remain relevant or informative features so that it is often preferred for alleviating the dimensionality curse, enhancing learning performance, providing better readability and ...

Abstract	Feature selection aims to remove irrelevant or redundant features and thereby remain relevant or informative features so that it is often preferred for alleviating the dimensionality curse, enhancing learning performance, providing better readability and interpretability, and so on. Data that contain numerical and categorical representations are called heterogeneous data, and they exist widely in many real-world applications. Neighborhood rough set (NRS) can effectively deal with heterogeneous data by using neighborhood binary relation, which has been successfully applied to heterogeneous feature selection. In this article, the NRS model as a unified framework is used to design a feature selection method to handle categorical, numerical, and heterogeneous data. First, the concept of neighborhood combination entropy (NCE) is presented. It can reflect the probability of pairs of the neighborhood granules that are probably distinguishable from each other. Then, the conditional neighborhood combination entropy (cNCE) based on NCE is proposed under the condition of considering decision attributes. Moreover, some properties and relationships between cNCE and NCE are derived. Finally, the functions of inner and outer significances are constructed to design a feature selection algorithm based on cNCE (FScNCE). The experimental results show the effectiveness and superiority of the proposed algorithm.
Language	English
Publishing date	2024-02-29
Publishing country	United States
Document type	Journal Article
ISSN	2162-2388
ISSN (online)	2162-2388
DOI	10.1109/TNNLS.2022.3193929
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Article ; Online: Comparative evaluation of soundscapes in human activities spatial contexts of pedestrian spaces adjacent to arterial roads.

Lu, Xiaodong / Xie, Zhuangxiu / Zhu, Peisheng / Dai, Xiaoling / Zhang, Yuan / Tao, Wanqi / Wang, Shiyuan

The Science of the total environment

2024 Volume 928, Page(s) 172198

Abstract: Pedestrian spaces adjacent to arterial roads are characterized by the dominance of traffic noise alongside various human activities. Research on the impact of traffic noise on the soundscape evaluation of pedestrian spaces has not considered human ... ...

Abstract	Pedestrian spaces adjacent to arterial roads are characterized by the dominance of traffic noise alongside various human activities. Research on the impact of traffic noise on the soundscape evaluation of pedestrian spaces has not considered human activities spatial contexts. To address this research gap, the present study constructed auditory environments for pedestrian spaces in the contexts of commuting, residential, and commercial activities. A total of seven auditory environments were subjected to laboratory auditory evaluations, including perceived dominance of sound source, acoustic comfort, and perceived affective quality of the soundscape. The results indicated that in pedestrian spaces with constant traffic noise, the presence of significant human activity sounds led to a decreased perceived dominance of traffic noise and an increased acoustic comfort, despite the higher acoustic energy. Thus, pedestrian spaces with a variety of human activity received better soundscape evaluations. The elements that reflected the human activities spatial contexts, including the types and intensity of human activities, played a crucial role in soundscape evaluations. Better acoustic comfort was reported in pedestrian spaces characterized by low-intensity residential activities and high-intensity commercial activities. Additionally, pedestrian spaces with more intense activities offered an actively engaging soundscape. The findings can provide reference for a more accurate evaluation of the soundscape in pedestrian spaces and guide the soundscape design of pedestrian environments.
Language	English
Publishing date	2024-04-04
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2024.172198
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