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  1. Book ; Online: Phytol and phytyldiol concentrations at DYFAMED time series station and sediment trap, supplementary data to: Cuny, Philippe; Marty, Jean-Claude; Chiav?rini, Jacques; Vescovali, Isabelle; Raphel, Danielle; Rontani, Jean-Fran?ois (2002): One-year seasonal survey of the chlorophyll photodegradation process in the northwestern Mediterranean Sea. Deep Sea Research Part II: Topical Studies in Oceanography, 49(11), 1987-2005

    Cuny, Philippe / Chiav?rini, Jacques / Marty, Jean-Claude / Raphel, Danielle / Rontani, Jean-Fran?ois / Vescovali, Isabelle

    2002  

    Abstract: Particulate samples from the water column were collected monthly from depths of 5-150 m, between May 1996 and March 1997, in the northwestern Mediterranean Sea (Ligurian Sea) as part of the DYFAMED project within the French JGOFS program. These samples ... ...

    Abstract Particulate samples from the water column were collected monthly from depths of 5-150 m, between May 1996 and March 1997, in the northwestern Mediterranean Sea (Ligurian Sea) as part of the DYFAMED project within the French JGOFS program. These samples were analyzed by gas chromatography-electron impact mass spectrometry for their phytol and 3-methylidene-3,7,11-trimethylhexadecan-1,2-diol (phytyldiol) content. The corresponding Chlorophyll Phytyl side chain Photodegradation Index, molar ratio of phytyldiol to phytol, was calculated and the mean amount of chlorophyll photodegraded within the euphotic zone estimated. Seasonal differences in the chlorophyll photodegradation process appear in the one-year study. The chlorophyll appeared more photodegraded in the surface water (generally more than 40% photodegraded at 5-10 m) than at the deep chlorophyll maximum (DCM) (40-50 m) observed in the summer stratified waters (about 20% photodegraded). This difference was attributed to the healthy state of the phytoplankton community (coincidence with the highest primary production levels) and to the lower intensity of irradiance at the DCM level. On the other hand, the bulk of the detrital chlorophyll (chlorophyll associated with phytodetritus, phaeopigments) undergoes photodegradation before it sinks out of the photic zone. However, in January (winter mixed water) the pigments exported towards the sea floor were less photodegraded. This is thought to result from a shorter period of residence of the pigments in the photic zone due to vertical convection and grazing activity of macrozooplankton (salps), which are producers of rapid sinking fecal pellets.
    Language English
    Dates of publication 2002-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/S0967-0645(02)00023-1
    DOI 10.1594/PANGAEA.738645
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  2. Book ; Online: Particulate organic carbon and nitrogen concentrations and fluxes at time series station DYNAPROC, supplementary data to: Goutx, Madeleine; Momzikoff, Andr?; Striby, L; Andersen, Val?rie; Marty, Jean-Claude; Vescovali, Isabelle (2000): High-frequency fluxes of labile compounds in the central Ligurian Sea, northwestern Mediterranean. Deep Sea Research Part I: Oceanographic Research Papers, 47(3), 533-556

    Goutx, Madeleine / Andersen, Val?rie / Marty, Jean-Claude / Momzikoff, Andr? / Striby, L / Vescovali, Isabelle

    2000  

    Abstract: Sinking particles were collected every 4?h with drifting sediment traps deployed at 200?m depth in May 1995 in a 1-D vertical system during the DYNAPROC observations in the northwestern Mediterranean sea. POC, proteins, glucosamine and lipid classes were ...

    Abstract Sinking particles were collected every 4?h with drifting sediment traps deployed at 200?m depth in May 1995 in a 1-D vertical system during the DYNAPROC observations in the northwestern Mediterranean sea. POC, proteins, glucosamine and lipid classes were used as indicators of the intensity and quality of the particle flux. The roles of day/night cycle and wind on the particle flux were examined. The transient regime of production from late spring bloom to pre-oligotrophy determined the flux intensity and quality. POC fluxes decreased from, on average, 34 to 11 mg/m**2/d, representing 6-14% of the primary production under late spring bloom conditions to 1-2% under pre-oligotrophic conditions. Total protein and chloroplast lipid fluxes correlated with POC and reflected the input of algal biomass into the traps. As the season proceeded, changes in the biochemical composition of the exported material were observed. The C/N ratio rose from 7.8 to 12. Increases of serine (10-28% of total proteins), total lipids (7-9 to 14-28% of POC) and reserve lipids (1-5 to 5-22% of total lipids) were noticeable, whereas total protein content in POC decreased (20-27 to 18-7%). N-acetyl glucosamine, a tracer of fecal pellet flux, showed that zooplankton grazing was a major vector of downward export during the decaying bloom. Against this background pattern, episodic events specifically increased the flux, modifying the quality and the settling velocity of particles. Day/night signals in biotracers (POC, N-acetyl glucosamine, protein and chloroplast lipids) showed that zooplankton migrations were responsible for sedimentation of fresh material through fast sinking particles (V=170-180?m/d) at night. Periodic signatures of re-processed material (high lipolysis and bacterial biomass indices) suggested that other zooplankton fecal pellets or small aggregates, probably of lower settling velocities (V<170?m/d), contributed to the flux during calm periods. At the beginning of the experiment, during the development of a prymnesiophyte bloom in the upper layers, the sterol signal with no periodicity enabled us to estimate high particle settling velocities (>=600?m/d) likely related to large aggregate formation. A wind event increased biotracer fluxes (POC, protein, chloroplast lipids). The rapid transmission of surface signals through extremely fast sinking particles could be a general feature of particle fluxes in marine areas unaffected by horizontal advection.
    Language English
    Dates of publication 2000-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/S0967-0637(99)00101-6
    DOI 10.1594/PANGAEA.738702
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  3. Book ; Conference proceedings: Energy and protein metabolism and nutrition

    Ortigues-Marty, Isabelle

    [proceedings of the 2nd EAAP International Symposium on Energy and Protein Metabolism and Nutrition]

    (EAAP publication ; 124)

    2007  

    Institution Europäische Vereinigung für Tierproduktion
    Event/congress International Symposium on Energy and Protein Metabolism and Nutrition (2, 2007, Vichy)
    Author's details scientific ed.: I. Ortigues-Marty. [ISEP 2007, France, Vichy, 9 - 13 Sept. Organised by EAAP]
    Series title EAAP publication ; 124
    Publication / European Association for Animal Production
    Collection Publication / European Association for Animal Production
    Language English
    Size 647 S. : Ill., graph. Darst.
    Publisher Wageningen Academic Publ
    Publishing place Wageningen
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    HBZ-ID HT015297279
    ISBN 978-90-8686-041-8 ; 90-8686-041-9
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

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    Shelf markLoan statusLocation
    078/1073 available for loan (reading room) Freihandmagazin (U1)

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  4. Article ; Online: Editorial.

    Ortigues-Marty, Isabelle

    Animal : an international journal of animal bioscience

    2018  Volume 12, Issue 1, Page(s) 1

    Language English
    Publishing date 2018-01-02
    Publishing country England
    Document type Editorial
    ZDB-ID 2257920-5
    ISSN 1751-732X ; 1751-7311
    ISSN (online) 1751-732X
    ISSN 1751-7311
    DOI 10.1017/S1751731117003081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Z 7718: Show issues

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  5. Article ; Online: Not just another kinase mutation!

    Plo, Isabelle / Marty, Caroline

    Blood

    2020  Volume 134, Issue 26, Page(s) 2335–2337

    MeSH term(s) Humans ; Hypereosinophilic Syndrome ; Janus Kinase 2 ; Leukemia ; Mutation ; Oncogenes ; Polycythemia Vera
    Chemical Substances JAK2 protein, human (EC 2.7.10.2) ; Janus Kinase 2 (EC 2.7.10.2)
    Language English
    Publishing date 2020-01-08
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2019003650
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.140: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 364: Show issues

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  6. Article ; Online: Recent advances in therapies for primary myelofibrosis.

    Vainchenker, William / Yahmi, Nasrine / Havelange, Violaine / Marty, Caroline / Plo, Isabelle / Constantinescu, Stefan N

    Faculty reviews

    2023  Volume 12, Page(s) 23

    Abstract: Primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET) form the ... ...

    Abstract Primary myelofibrosis (PMF), polycythemia vera (PV) and essential thrombocythemia (ET) form the classical
    Language English
    Publishing date 2023-09-26
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2732-432X
    ISSN (online) 2732-432X
    DOI 10.12703/r/12-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Gene therapies for RyR1-related myopathies.

    Marty, Isabelle / Beaufils, Mathilde / Fauré, Julien / Rendu, John

    Current opinion in pharmacology

    2022  Volume 68, Page(s) 102330

    Abstract: Myopathies related to variations in the RYR1 gene are genetic diseases for which the therapeutic options are sparse, in part because of the very large size of the gene and protein, and of the distribution of variations all along the sequence. Taking ... ...

    Abstract Myopathies related to variations in the RYR1 gene are genetic diseases for which the therapeutic options are sparse, in part because of the very large size of the gene and protein, and of the distribution of variations all along the sequence. Taking advantage of the progress made in the gene therapy field, different approaches can be applied to the different genetic variations, either at the mRNA level or directly at the DNA level, specifically with the new gene editing tools. Some of those have already been tested in cellulo and/or in vivo, and for the development of the most innovative gene editing technology, inspiration can be sought in other genetic diseases.
    MeSH term(s) Humans ; Ryanodine Receptor Calcium Release Channel/genetics ; Ryanodine Receptor Calcium Release Channel/metabolism ; Muscular Diseases/genetics ; Muscular Diseases/therapy ; Muscular Diseases/metabolism ; Muscle, Skeletal/metabolism ; Mutation
    Chemical Substances Ryanodine Receptor Calcium Release Channel
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2037057-X
    ISSN 1471-4973 ; 1471-4892
    ISSN (online) 1471-4973
    ISSN 1471-4892
    DOI 10.1016/j.coph.2022.102330
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5608: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Triadin regulation of the ryanodine receptor complex.

    Marty, Isabelle

    The Journal of physiology

    2015  Volume 593, Issue 15, Page(s) 3261–3266

    Abstract: The calcium release complex is the major player in excitation-contraction coupling, both in cardiac and skeletal muscle. The core of the complex is the ryanodine receptor, and triadin is a regulating protein. Nevertheless, the precise function of triadin ...

    Abstract The calcium release complex is the major player in excitation-contraction coupling, both in cardiac and skeletal muscle. The core of the complex is the ryanodine receptor, and triadin is a regulating protein. Nevertheless, the precise function of triadin is only partially understood. Besides its function in the anchoring of calsequestrin at the triad/dyad, our recent results allow us to propose hypotheses on new triadin scaffolding functions, based on the studies performed using different models, from triadin knockout mice to human patients, and expression in non-muscle cells, taking into account the presence of multiple triadin isoforms.
    MeSH term(s) Animals ; Calcium Signaling ; Carrier Proteins/metabolism ; Congresses as Topic ; Humans ; Muscle Proteins/metabolism ; Ryanodine Receptor Calcium Release Channel/metabolism
    Chemical Substances Carrier Proteins ; Muscle Proteins ; Ryanodine Receptor Calcium Release Channel ; triadin
    Language English
    Publishing date 2015-08-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/jphysiol.2014.281147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uc I Zs.65: Show issues Location:
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  9. Article ; Online: Triadin regulation of the ryanodine receptor complex.

    Marty, Isabelle

    The Journal of physiology

    2014  

    Abstract: The calcium release complex is the major player in excitation-contraction coupling, both in cardiac and skeletal muscle. The core of the complex is the ryanodine receptor, and triadin is a regulating protein. Nevertheless, the precise function of triadin ...

    Abstract The calcium release complex is the major player in excitation-contraction coupling, both in cardiac and skeletal muscle. The core of the complex is the ryanodine receptor, and triadin is a regulating protein. Nevertheless, the precise function of triadin is only partially understood. Besides its function in the anchoring of calsequestrin at the triad/dyad, our recent results allow us to propose hypotheses on new triadin scaffolding functions, based on the studies performed using different models, from triadin knockout mice to human patients, and expression in non-muscle cells, taking into account the presence of multiple triadin isoforms.
    Language English
    Publishing date 2014-09-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/jphysiol.2014.281147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.65: Show issues Location:
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  10. Article ; Online: Enzymes' Power for Plastics Degradation.

    Tournier, Vincent / Duquesne, Sophie / Guillamot, Frédérique / Cramail, Henri / Taton, Daniel / Marty, Alain / André, Isabelle

    Chemical reviews

    2023  Volume 123, Issue 9, Page(s) 5612–5701

    Abstract: Plastics are everywhere in our modern way of living, and their production keeps increasing every year, causing major environmental concerns. Nowadays, the end-of-life management involves accumulation in landfills, incineration, and recycling to a lower ... ...

    Abstract Plastics are everywhere in our modern way of living, and their production keeps increasing every year, causing major environmental concerns. Nowadays, the end-of-life management involves accumulation in landfills, incineration, and recycling to a lower extent. This ecological threat to the environment is inspiring alternative bio-based solutions for plastic waste treatment and recycling toward a circular economy. Over the past decade, considerable efforts have been made to degrade commodity plastics using biocatalytic approaches. Here, we provide a comprehensive review on the recent advances in enzyme-based biocatalysis and in the design of related biocatalytic processes to recycle or upcycle commodity plastics, including polyesters, polyamides, polyurethanes, and polyolefins. We also discuss scope and limitations, challenges, and opportunities of this field of research. An important message from this review is that polymer-assimilating enzymes are very likely part of the solution to reaching a circular plastic economy.
    MeSH term(s) Plastics/metabolism ; Polyurethanes ; Polymers ; Recycling
    Chemical Substances Plastics ; Polyurethanes ; Polymers
    Language English
    Publishing date 2023-03-14
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 207949-5
    ISSN 1520-6890 ; 0009-2665
    ISSN (online) 1520-6890
    ISSN 0009-2665
    DOI 10.1021/acs.chemrev.2c00644
    Database MEDical Literature Analysis and Retrieval System OnLINE

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