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Article ; Online: Trials and tribulations in systemic lupus erythematosus.

Wofsky, David

Bulletin of the NYU hospital for joint diseases

2010  Volume 68, Issue 3, Page(s) 175–178

Abstract: The pace of clinical trials activity in systemic lupus erythematosus (SLE) continues to accelerate. After decades of reliance on largely empiric approaches, a solid evidence-based foundation to guide our use of traditional agents, such as ... ...

Abstract The pace of clinical trials activity in systemic lupus erythematosus (SLE) continues to accelerate. After decades of reliance on largely empiric approaches, a solid evidence-based foundation to guide our use of traditional agents, such as cyclophosphamide and azathioprine, is finally developing. In addition, we are learning how to integrate relatively new immunosuppressive agents, such as mycophenolate mofetil, into the treatment of SLE. These advances provide an important backdrop for recent trials designed to determine the potential value of several promising biologic therapies for SLE.
MeSH term(s) Clinical Trials as Topic ; Evidence-Based Medicine ; Humans ; Immunosuppressive Agents/therapeutic use ; Lupus Erythematosus, Systemic/drug therapy ; Treatment Outcome
Chemical Substances Immunosuppressive Agents
Language English
Publishing date 2010
Publishing country United States
Document type Journal Article ; Review
ZDB-ID 390411-8
ISSN 1936-9727 ; 2328-5273 ; 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
ISSN (online) 1936-9727 ; 2328-5273
ISSN 1936-9719 ; 0018-5647 ; 0883-9344 ; 2328-4633
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