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  1. Book: Electrophysiological foundations of cardiac arrhythmias

    Wit, Andrew L. / Wellens, Hein J. J. / Josephson, Mark E.

    a bridge between basic mechanisms and clincial electrophysiology

    2017  

    Author's details Andrew L. Wit, Jein J. Wellens, Mark E. Josephson
    Language English
    Size xxiv, 648 Seiten, Illustrationen, Diagramme
    Publisher Cardiotext Publishing
    Publishing place Minneapolis, Minn
    Publishing country United States
    Document type Book
    Accompanying material Zugang zu Online-Ausgabe über Code
    HBZ-ID HT017167223
    ISBN 978-0-9790164-5-5 ; 9781942909125 ; 0-9790164-5-2 ; 1942909128
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: HRS 40th anniversary viewpoints: Present at the creation-My viewpoint on the origins of cellular and clinical electrophysiology of arrhythmias.

    Wit, Andrew L

    Heart rhythm

    2019  Volume 16, Issue 8, Page(s) 1294–1295

    MeSH term(s) Anniversaries and Special Events ; Arrhythmias, Cardiac/history ; Arrhythmias, Cardiac/physiopathology ; Electrophysiologic Techniques, Cardiac/history ; Heart Conduction System/physiopathology ; History, 20th Century ; Humans
    Language English
    Publishing date 2019-07-29
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2019.05.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Afterdepolarizations and triggered activity as a mechanism for clinical arrhythmias.

    Wit, Andrew L

    Pacing and clinical electrophysiology : PACE

    2018  

    Abstract: Afterdepolarizations cause triggered arrhythmias. One kind occurs after repolarization is complete, delayed afterdepolarizations (DADs). Another occurs as an interruption in repolarization, early afterdepolarizations (EADs). Afterdepolarizations initiate ...

    Abstract Afterdepolarizations cause triggered arrhythmias. One kind occurs after repolarization is complete, delayed afterdepolarizations (DADs). Another occurs as an interruption in repolarization, early afterdepolarizations (EADs). Afterdepolarizations initiate arrhythmias when they depolarize membrane potential to threshold potential for triggering action potentials. DADs usually occur mostly when Ca
    Language English
    Publishing date 2018-06-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.13419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Mark E. Josephson, MD, Personal Remembrances.

    Wit, Andrew L

    Heart rhythm

    2017  Volume 14, Issue 5, Page(s) 631–633

    Language English
    Publishing date 2017
    Publishing country United States
    Document type Editorial
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2017.02.029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Interaction Between Na

    Kleber, Andre G / Wit, Andrew L

    Circulation research

    2020  Volume 127, Issue 12, Page(s) 1549–1551

    MeSH term(s) Heart ; Sodium
    Chemical Substances Sodium (9NEZ333N27)
    Language English
    Publishing date 2020-12-03
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80100-8
    ISSN 1524-4571 ; 0009-7330 ; 0931-6876
    ISSN (online) 1524-4571
    ISSN 0009-7330 ; 0931-6876
    DOI 10.1161/CIRCRESAHA.120.318316
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Editorial Commentary: Important contributions of basic electrophysiology to the prevention and therapy of drug induced cardiac arrhythmias.

    Wit, Andrew L

    Trends in cardiovascular medicine

    2017  Volume 27, Issue 7, Page(s) 460–462

    Language English
    Publishing date 2017-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2017.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Basic Electrophysiologic Mechanisms of Sudden Cardiac Death Caused by Acute Myocardial Ischemia and Infarction.

    Wit, Andrew L

    Cardiac electrophysiology clinics

    2017  Volume 9, Issue 4, Page(s) 525–536

    Abstract: Sudden cardiac death caused by acute ischemia results from electrophysiologic changes in myocardium deprived of its blood supply. These changes include a reduction in resting potential and phase 0 depolarization and an increase in intercellular ... ...

    Abstract Sudden cardiac death caused by acute ischemia results from electrophysiologic changes in myocardium deprived of its blood supply. These changes include a reduction in resting potential and phase 0 depolarization and an increase in intercellular resistivity that slow conduction, cause conduction block, and lead to reentrant excitation and ventricular fibrillation. Reperfusion of a coronary artery after a short period of occlusion leads to similar changes.
    MeSH term(s) Action Potentials/physiology ; Death, Sudden, Cardiac ; Electrophysiological Phenomena/physiology ; Gap Junctions/physiology ; Humans ; Myocardial Infarction/physiopathology ; Myocardial Ischemia/physiopathology
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2017.07.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comment on the First Symposium on Quantitative Analysis of Cardiac Arrhythmias.

    Wit, Andrew L

    Computers in biology and medicine

    2015  Volume 65, Page(s) 149

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/physiopathology ; Congresses as Topic ; Electrophysiologic Techniques, Cardiac ; Humans
    Language English
    Publishing date 2015-10-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2015.04.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Challenges Associated with Interpreting Mechanisms of AF.

    Roney, Caroline H / Wit, Andrew L / Peters, Nicholas S

    Arrhythmia & electrophysiology review

    2020  Volume 8, Issue 4, Page(s) 273–284

    Abstract: Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus regarding the mechanisms causing AF. Studies report different mechanisms for AF, ranging from hierarchical drivers to anarchical multiple ... ...

    Abstract Determining optimal treatment strategies for complex arrhythmogenesis in AF is confounded by the lack of consensus regarding the mechanisms causing AF. Studies report different mechanisms for AF, ranging from hierarchical drivers to anarchical multiple activation wavelets. Differences in the assessment of AF mechanisms are likely due to AF being recorded across diverse models using different investigational tools, spatial scales and clinical populations. The authors review different AF mechanisms, including anatomical and functional re-entry, hierarchical drivers and anarchical multiple wavelets. They then describe different cardiac mapping techniques and analysis tools, including activation mapping, phase mapping and fibrosis identification. They explain and review different data challenges, including differences between recording devices in spatial and temporal resolutions, spatial coverage and recording surface, and report clinical outcomes using different data modalities. They suggest future research directions for investigating the mechanisms underlying human AF.
    Language English
    Publishing date 2020-05-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2813970-7
    ISSN 2050-3377 ; 2050-3369
    ISSN (online) 2050-3377
    ISSN 2050-3369
    DOI 10.15420/aer.2019.08
    Database MEDical Literature Analysis and Retrieval System OnLINE

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