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  1. Article: Impact Assessment on Floral Composition and Spread Potential of Mikania micrantha H.B.K. in an Urban Scenario

    Banerjee, Achyut Kumar / C. Sudhakar Reddy / Anjana Dewanji

    Proceedings of the National Academy of Sciences, India, Section B: biological sciences. 2017 Sept., v. 87, no. 3

    2017  

    Abstract: ... H.B.K., and its growth in a rapidly urbanizing city, Kolkata. The two primary objectives were ...

    Abstract The present study is concerned with one of the top ten worst weeds of the world, Mikania micrantha H.B.K., and its growth in a rapidly urbanizing city, Kolkata. The two primary objectives were to assess the impact of this invasive plant on floral diversity as well as its potential for spread into new areas. A quadrat based assessment was conducted to estimate the impact of M. micrantha on floral diversity at 69 terrestrial sites which were subsequently grouped on the basis of the infestation size of M. micrantha. A significant reduction in the number of native species with increasing infestation size of M. micrantha was noted. The clay component of soil texture along major roadsides, as found in this study, significantly favoured extra-large growth of M. micrantha in contrast to the sandy loam soil type which generally favours their luxuriant growth in forest areas. The ‘distance from road network’ analysis revealed that most of the large infestations were along highways and that the satellite infestations of M. micrantha did not readily progress into larger infestations along minor roads. Application of remote sensing technology identified the vulnerability of the ‘sparse vegetation’ land use class for future spread of infestation. Although majority of the infested sites comprised of satellite populations with very few extra-large patches, the rapid rate of urbanization within cities highlights the need for ‘early detection and rapid response’ to prevent large scale invasion in future.
    Keywords Mikania micrantha ; cities ; clay ; ecological invasion ; forests ; highways ; indigenous species ; invasive species ; land use ; remote sensing ; sandy loam soils ; urbanization ; weeds ; India
    Language English
    Dates of publication 2017-09
    Size p. 777-788.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2707745-7
    ISSN 2250-1746 ; 0369-8211
    ISSN (online) 2250-1746
    ISSN 0369-8211
    DOI 10.1007/s40011-015-0650-6
    Database NAL-Catalogue (AGRICOLA)

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  2. Article: Microwave-assisted, montmorillonite K-10 catalyzed three-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions

    Veeranarayana Reddy, Mudumala / Reddy, Gangireddy Chandra Sekhar / Jeong, Yeon Tae

    Tetrahedron. 2012 Aug. 26, v. 68, no. 34

    2012  

    Abstract: An efficient, rapid, and green synthesis of 2H-indazolo[2,1-b]phthalazine-triones has been ... Montmorillonite K-10 combination and offers many advantages, such as excellent product yields, shorter ...

    Abstract An efficient, rapid, and green synthesis of 2H-indazolo[2,1-b]phthalazine-triones has been accomplished under solvent-free conditions by the reaction of phthalhydrazide, aldehydes and 5,5-dimethylcyclohexane-1,3-dione. This approach exploits the synthetic potential of microwave irradiation and Montmorillonite K-10 combination and offers many advantages, such as excellent product yields, shorter reaction time, reusable catalyst, easy isolation of products, and environmentally benign reaction conditions.
    Keywords aldehydes ; catalysts ; chemical reactions ; chemical structure ; microwave radiation ; microwave treatment ; montmorillonite
    Language English
    Dates of publication 2012-0826
    Size p. 6820-6828.
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 204285-x
    ISSN 1464-5416 ; 0040-4020 ; 0563-2064
    ISSN (online) 1464-5416
    ISSN 0040-4020 ; 0563-2064
    DOI 10.1016/j.tet.2012.06.045
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells.

    Pelish, Henry E / Ciesla, William / Tanaka, Nori / Reddy, Krishna / Shair, Matthew D / Kirchhausen, Tomas / Lencer, Wayne I

    Biochemical pharmacology

    2006  Volume 71, Issue 12, Page(s) 1720–1726

    Abstract: ... intestinal cell line T84. Secramine B interfered with a cAMP-gated and Ba2+-sensitive K+ channel, presumably ... in the regulation of the chloride secretory response and identify secramine B an inhibitor of cAMP-dependent K+ ... V. cholerae infection and can be life threatening. Here we report that secramine B, a small molecule ...

    Abstract Cyclic AMP- (cAMP) and calcium-dependent agonists stimulate chloride secretion through the coordinated activation of distinct apical and basolateral membrane channels and ion transporters in mucosal epithelial cells. Defects in the regulation of Cl- transport across mucosal surfaces occur with cystic fibrosis and V. cholerae infection and can be life threatening. Here we report that secramine B, a small molecule that inhibits activation of the Rho GTPase Cdc42, reduced cAMP-stimulated chloride secretion in the human intestinal cell line T84. Secramine B interfered with a cAMP-gated and Ba2+-sensitive K+ channel, presumably KCNQ1/KCNE3. This channel is required to maintain the membrane potential that sustains chloride secretion. In contrast, secramine B did not affect the Ca2+-mediated chloride secretion pathway, which requires a separate K+ channel activity from that of cAMP. Pirl1, another small molecule structurally unrelated to secramine B that also inhibits Cdc42 activation in vitro, similarly inhibited cAMP-dependent but not Ca2+-dependent chloride secretion. These results suggest that Rho GTPases may be involved in the regulation of the chloride secretory response and identify secramine B an inhibitor of cAMP-dependent K+ conductance in intestinal epithelial cells.
    MeSH term(s) Benzazepines/pharmacology ; Cell Line ; Cyclic AMP/antagonists & inhibitors ; Cyclic AMP/pharmacology ; Humans ; Intestinal Mucosa/cytology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/metabolism ; Ion Channel Gating ; Ion Transport ; Potassium/metabolism ; cdc42 GTP-Binding Protein/antagonists & inhibitors
    Chemical Substances Benzazepines ; secramine B ; Cyclic AMP (E0399OZS9N) ; cdc42 GTP-Binding Protein (EC 3.6.5.2) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 2006-03-18
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 208787-x
    ISSN 1873-2968 ; 0006-2952
    ISSN (online) 1873-2968
    ISSN 0006-2952
    DOI 10.1016/j.bcp.2006.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: SlumberNet: deep learning classification of sleep stages using residual neural networks.

    Jha, Pawan K / Valekunja, Utham K / Reddy, Akhilesh B

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4797

    Abstract: ... conditions. Employing k-fold cross-validation and data augmentation techniques, SlumberNet achieved high ...

    Abstract Sleep research is fundamental to understanding health and well-being, as proper sleep is essential for maintaining optimal physiological function. Here we present SlumberNet, a novel deep learning model based on residual network (ResNet) architecture, designed to classify sleep states in mice using electroencephalogram (EEG) and electromyogram (EMG) signals. Our model was trained and tested on data from mice undergoing baseline sleep, sleep deprivation, and recovery sleep, enabling it to handle a wide range of sleep conditions. Employing k-fold cross-validation and data augmentation techniques, SlumberNet achieved high levels of overall performance (accuracy = 97%; F1 score = 96%) in predicting sleep stages and showed robust performance even with a small and diverse training dataset. Comparison of SlumberNet's performance to manual sleep stage classification revealed a significant reduction in analysis time (~ 50 × faster), without sacrificing accuracy. Our study showcases the potential of deep learning to facilitate sleep research by providing a more efficient, accurate, and scalable method for sleep stage classification. Our work with SlumberNet further demonstrates the power of deep learning in mouse sleep research.
    MeSH term(s) Animals ; Mice ; Deep Learning ; Neural Networks, Computer ; Sleep Stages/physiology ; Sleep ; Polysomnography/methods ; Electroencephalography/methods
    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-54727-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A study on measure of resilience and impact of demanding clinical training on young medical professional's burnout in a tertiary care hospital, Andhra Pradesh.

    Thomas, K Roma / Reddy, B Venkatashiva

    Journal of education and health promotion

    2023  Volume 12, Page(s) 390

    Abstract: Background: The psychological state of medical students gaining concern on the part of medical institutions in several countries. Numerous studies are being conducted to study stress, burnout, and depression in medical students in India and globally. ... ...

    Abstract Background: The psychological state of medical students gaining concern on the part of medical institutions in several countries. Numerous studies are being conducted to study stress, burnout, and depression in medical students in India and globally. However, little is known about medical student resilience, particularly in India. The objectives of this study were to study the resilience, self-perceptions of stress coping skills, and burnout among medical students in clinical training in a tertiary care health center, to study factors associated with resilience among medical students in clinical training in a tertiary care health center and to study the relationship between resilience and self-perceptions of stress coping skills and symptoms of burnout.
    Materials and methods: This cross-sectional study was conducted in a tertiary healthcare hospital in district Guntur, Andhra Pradesh from November 2020 to December 2020, among 186 adult male and female medical students, aged more than 20 years, enrolled in the regular degree course and part of patient care or at least last three months. Participants were randomly selected and a structured questionnaire with Connor Davidson Resilience Scale 10 was used for interviewing. Descriptive and inferential statistics were conducted to measure associations between outcome and explanatory variables. We used multiple linear regression to examine the association between dependent and independent variables. A
    Results: In the present study, 109 (58.0%) were females. The mean age of the study participants was 25.4 years (standard deviation 2.78). The mean score resilience score of the study participants using Connor Davidson Resilience Scale 10 was 25.1 (standard deviation 7.97). Of the total 44 (23.7%) of the study, participants reported the presence of burnout. A significant positive correlation was between resilience and self-perceptions of stress-coping skills with a Pearson Correlation coefficient of 0.393. Among the study participants, the mean resilience score was higher among those not having any symptoms of burnout. In the hierarchical stepwise multiple linear regression analysis, male gender (
    Conclusion: Our study samples had higher resilience and lower burnout prevalence compared to the West. The stressful clinical event experienced by medical students demands training and innovative strategies to foster communication and teamwork skills among medical teams.
    Language English
    Publishing date 2023-11-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2715449-X
    ISSN 2319-6440 ; 2277-9531
    ISSN (online) 2319-6440
    ISSN 2277-9531
    DOI 10.4103/jehp.jehp_321_23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Canine ocular thelaziosis: first report in Andhra Pradesh.

    Sivajothi, S / Sudhakara Reddy, B / Swetha, K

    Journal of parasitic diseases : official organ of the Indian Society for Parasitology

    2023  Volume 47, Issue 3, Page(s) 689–691

    Abstract: Thelaziosis is a vector-borne zoonotic disease with worldwide distribution, including in India and reports on canine ocular thelaziosis are very limited. The present case documentation will provide basic information to initiate the geographical ... ...

    Abstract Thelaziosis is a vector-borne zoonotic disease with worldwide distribution, including in India and reports on canine ocular thelaziosis are very limited. The present case documentation will provide basic information to initiate the geographical epidemiological studies which will help to prevent the spread to these zoonotic diseases in the specified location. This communication reports about the rare case of canine ocular thelaziosis in Andhra Pradesh with the morphological features of the parasite and the management of ocular manifestations with suitable antimicrobial and anti-inflammatory eye drops along with ivermectin injections.
    Language English
    Publishing date 2023-05-25
    Publishing country India
    Document type Journal Article
    ZDB-ID 2548456-4
    ISSN 0975-0703 ; 0971-7196
    ISSN (online) 0975-0703
    ISSN 0971-7196
    DOI 10.1007/s12639-023-01597-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Numerical entropy analysis of MHD electro-osmotic flow of peristaltic movement in a nanofluid.

    Reddy, M Gnaneswara / Reddy, K Venugopal / Souayeh, Basma / Fayaz, H

    Heliyon

    2024  Volume 10, Issue 5, Page(s) e27185

    Abstract: The present study investigates the MHD electro-osmotic flow of entropy generation analysis for peristaltic movement in a nanofluid with temperature-dependent viscosity. Long wavelengths, i.e., The magnitude of a wave's energy corresponds directly to its ... ...

    Abstract The present study investigates the MHD electro-osmotic flow of entropy generation analysis for peristaltic movement in a nanofluid with temperature-dependent viscosity. Long wavelengths, i.e., The magnitude of a wave's energy corresponds directly to its frequency while being inversely related to its wavelength in terms of velocity, temperature, and concentration, govern and confine the flow stream in the laminar region. Ohmic heating and hall effects are also included. Graphs are used to obtain and examine numerical solutions for axial velocity, temperature, concentration, Bejan number, and entropy generation. The effects of this research can help to improve pumping and gastrointestinal movements in different engineering devices. Debye-Huckel and lubrication approximations are studied to access the Boltzmann distribution of electric potential across an electric double layer. The investigations of an existing model are important in illuminating the microfluidics machinery used at the micro level for various transport phenomena in which fluids as well as particles are transported together. The current study has many applications and can be further extended to a three-dimensional profile with appropriate modifications and assumptions. When studying entropy generation, it is essential to examine the irreversible factors, while also taking into account the velocity and thermal slip conditions at channel boundaries. Moreover, the concept of entropy generation holds significant importance in comprehending various biological phenomena. Hence, the current research holds promising implications for both industrial and medical fields. The entropy generation is minimum at left wall of the channel for negative values of Helmholtz-Smoluchowski velocity.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e27185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Visible Light-Induced Metal-free Arylation of Coumarin-3-carboxylates with Arylboronic Acids.

    Banik, Swarnayu / Saikiran, Aita / Permula, Prathyusha / Srivishnu, K S / Sridhar, B / Reddy, B V Subba

    Chemistry, an Asian journal

    2024  Volume 19, Issue 8, Page(s) e202400042

    Abstract: The present work represents a novel methodology for the selective arylation of coumarin-3-carboxylates with arylboronic acids via a photochemical route, marking the first-ever attempt for the direct alkenyl C-H arylation using rose bengal as a ... ...

    Abstract The present work represents a novel methodology for the selective arylation of coumarin-3-carboxylates with arylboronic acids via a photochemical route, marking the first-ever attempt for the direct alkenyl C-H arylation using rose bengal as a photocatalyst, which is a readily available and cost-effective alternative to transition metal catalysis. The reaction proceeds smoothly in MeOH/H
    Language English
    Publishing date 2024-03-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202400042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Risk factors, clinical indicators, and pathological findings of abomasal ulcers in tropical dairy buffaloes.

    Yasaswini, Duvvuru / Kumari, K Nalini / Shobhamani, B / Prameela, D Rani / Reddy, B Sudhakara / Reddy, K Praveen / Reddy, P Ravi Kanth

    Veterinary research communications

    2023  Volume 47, Issue 3, Page(s) 1139–1154

    Abstract: The current study aimed at identifying the risk factors and initial diagnostic aids for abomasal ulcers. The risk factor analysis confirmed a significant association (P < 0.05) of abomasal ulcers with concentrate-rich diets (OR, 4.795; CI, 1.212-15.974) ... ...

    Abstract The current study aimed at identifying the risk factors and initial diagnostic aids for abomasal ulcers. The risk factor analysis confirmed a significant association (P < 0.05) of abomasal ulcers with concentrate-rich diets (OR, 4.795; CI, 1.212-15.974) and concurrent disorders (OR, 2.978; CI, 0.987-8.980), while the buffaloes in early lactation (OR, 2.777; CI, 0.703-10.972) showed a higher tendency (P = 0.078) for the disorder. The depressed demeanour, dark or black manure (melena), anemia, tachycardia, decreased milk production, anorexia, tachypnea, absence of rumination, abdominal guarding, kyphosis, and tachypnea were the most frequent clinical signs. Subjecting the abomasal fluid for cultural isolation, gram staining, and stormy clot fermentation test identified the presence of clostridium perfringes, while screening through uniplex PCR detected cpa toxin. The buffaloes affected with type-3 and 4 abomasal ulcers exhibited a higher peritoneal fluid to serum ratio of total protein, albumin, and glucose with a low (P < 0.01) serum-ascites albumin gradient (SAAG) concentration compared to reference values of healthy buffaloes. The first two principal components of PCA explained 54.50% of the total variances with lymphocytes, creatine kinase, and rumen chloride levels as the top contributors to dimension I, and albumin, total protein, sodium, and methylene blue reduction time (MBRT) for rumen liquor as the major contributors to dimension II. The vector plot revealed lymphocytopenia, decreased hemoglobin, hypoalbuminemia, hypokalemia, decreased rumen pH, neutrophilia, eosinophilia, leucocytosis, greater MBRT, and higher rumen chloride, serum creatine kinase, and blood urea nitrogen as the major indicators for abomasal ulcers. Histopathological studies revealed infiltration of inflammatory cells in the mucosa along with multifocal areas of necrosis, degeneration, and eroded muscle structure. The study projected a few high-scored clinical signs and extremely variable clinical indicators as initial diagnostic aids of abomasal ulcers, which can be confirmed by ultrasonography and peritoneal fluid examination.
    MeSH term(s) Female ; Animals ; Ulcer/complications ; Ulcer/metabolism ; Ulcer/veterinary ; Buffaloes ; Chlorides/metabolism ; Stomach Ulcer/complications ; Stomach Ulcer/pathology ; Stomach Ulcer/veterinary ; Lactation/physiology ; Risk Factors ; Rumen/pathology
    Chemical Substances Chlorides
    Language English
    Publishing date 2023-01-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 406735-6
    ISSN 1573-7446 ; 0165-7380
    ISSN (online) 1573-7446
    ISSN 0165-7380
    DOI 10.1007/s11259-023-10070-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Transition metals-doped g-C

    Kalidasan, Kavya / Mallapur, Srinivas / Munirathnam, K / Nagarajaiah, H / Reddy, M B Madhusudana / Kakarla, Raghava Reddy / Raghu, Anjanapura V

    Chemosphere

    2024  Volume 352, Page(s) 141354

    Abstract: Graphitic carbon nitride (g- ... ...

    Abstract Graphitic carbon nitride (g-C
    MeSH term(s) Catalysis ; Light ; Nanostructures ; Semiconductors ; Wastewater
    Chemical Substances Wastewater
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2024.141354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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