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  1. Article: True Heroes of COVID-19 Battle - Our Nightingales.

    Francis, Varsha / Gulia, Ashish

    Indian journal of palliative care

    2020  Volume 26, Issue Suppl 1, Page(s) S184–S185

    Keywords covid19
    Language English
    Publishing date 2020-06-30
    Publishing country India
    Document type Journal Article
    ISSN 0973-1075
    ISSN 0973-1075
    DOI 10.4103/IJPC.IJPC_204_20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: True heroes of COVID-19 battle – Our nightingales

    Varsha Francis / Ashish Gulia

    Indian Journal of Palliative Care, Vol 26, Iss 5, Pp 184-

    2020  Volume 185

    Keywords Medicine (General) ; R5-920 ; covid19
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: True heroes of COVID-19 battle – Our nightingales

    Gulia, Ashish / Francis, Varsha

    Indian Journal of Palliative Care

    2020  Volume 26, Issue 5, Page(s) 184

    Keywords Public Health, Environmental and Occupational Health ; Health Policy ; covid19
    Language English
    Publisher Medknow
    Publishing country in
    Document type Article ; Online
    ISSN 0973-1075
    DOI 10.4103/ijpc.ijpc_204_20
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Inflammatory Subcutaneous Pseudotumour due to Migrating Foreign Body through Concealed Colonic Perforation

    Vikas Jadhav / Varsha Rangankar / Anmol Singh / Purnachandra Lamghare / Merry Francis Kallely

    Journal of Clinical and Diagnostic Research, Vol 16, Iss 4, Pp TD03-TD

    A Case Report

    2022  Volume 05

    Abstract: Foreign body ingestion though a common occurrence, rarely leads to bowel perforation. Thus, foreign body migration presents a diagnostic challenge. The author presents a case report of a 75-year-old female with a inflammatory subcutaneous pseudotumour ... ...

    Abstract Foreign body ingestion though a common occurrence, rarely leads to bowel perforation. Thus, foreign body migration presents a diagnostic challenge. The author presents a case report of a 75-year-old female with a inflammatory subcutaneous pseudotumour due to migrating foreign body through a concealed colonic perforation. The patient presented with insidious abdominal pain and fever since two months, with local tenderness and palpable lumbar in right lumbar region on examination. The diagnosis was initially made on ultrasound and confirmed on Computed Tomography (CT). Surgical removal of the foreign body was done.
    Keywords abscess ; chicken bone ; computed tomography ; foreign body ingestion ; ultrasound ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Amine functionalized carbon quantum dots from paper precursors for selective binding and fluorescent labelling applications

    Lisa John, Varsha / Joy, Francis / Jose Kollannoor, Amy / Joseph, Kuruvilla / Nair, Yamuna / T. P., Vinod

    Journal of colloid and interface science. 2022 July, v. 617

    2022  

    Abstract: We report a novel synthesis route for preparing carbon quantum dots (CQDs) of customized surface functionality from readily available precursors. The synthetic strategy is based on the chemical modification of paper precursors prior to preparing CQDs ... ...

    Abstract We report a novel synthesis route for preparing carbon quantum dots (CQDs) of customized surface functionality from readily available precursors. The synthetic strategy is based on the chemical modification of paper precursors prior to preparing CQDs from them. The pre-synthesis modification of paper precursors with (3-Aminopropyl) triethoxy silane (APTES) enabled us to synthesize CQDs with amine functional groups on the surface. The silane coupling via condensation between the ethoxy group of APTES and the cellulose hydroxyl group on the paper resulted in the tethering of amine groups on the paper substrates, which are retained as surface-bound species during the synthesis of CQDs from the modified paper. Amine functionalization on the surface of CQDs helped us use them in applications such as DNA binding. We analyzed the interaction of CQDs with calf thymus DNA (CT-DNA), and the results imply their propensity as an efficient biological probe. The synthetic strategy presented here can also be extended to other functional groups.
    Keywords DNA ; calves ; cellulose ; fluorescence ; paper ; silane
    Language English
    Dates of publication 2022-07
    Size p. 730-744.
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.03.070
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Amine functionalized carbon quantum dots from paper precursors for selective binding and fluorescent labelling applications.

    Lisa John, Varsha / Joy, Francis / Jose Kollannoor, Amy / Joseph, Kuruvilla / Nair, Yamuna / T P, Vinod

    Journal of colloid and interface science

    2022  Volume 617, Page(s) 730–744

    Abstract: We report a novel synthesis route for preparing carbon quantum dots (CQDs) of customized surface functionality from readily available precursors. The synthetic strategy is based on the chemical modification of paper precursors prior to preparing CQDs ... ...

    Abstract We report a novel synthesis route for preparing carbon quantum dots (CQDs) of customized surface functionality from readily available precursors. The synthetic strategy is based on the chemical modification of paper precursors prior to preparing CQDs from them. The pre-synthesis modification of paper precursors with (3-Aminopropyl) triethoxy silane (APTES) enabled us to synthesize CQDs with amine functional groups on the surface. The silane coupling via condensation between the ethoxy group of APTES and the cellulose hydroxyl group on the paper resulted in the tethering of amine groups on the paper substrates, which are retained as surface-bound species during the synthesis of CQDs from the modified paper. Amine functionalization on the surface of CQDs helped us use them in applications such as DNA binding. We analyzed the interaction of CQDs with calf thymus DNA (CT-DNA), and the results imply their propensity as an efficient biological probe. The synthetic strategy presented here can also be extended to other functional groups.
    MeSH term(s) Amines ; Carbon ; DNA ; Quantum Dots ; Silanes
    Chemical Substances Amines ; Silanes ; Carbon (7440-44-0) ; DNA (9007-49-2)
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2022.03.070
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 71/707: Show issues

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  8. Article: Rapid Formation and Rupture of Multiple Abdominal Pseudoaneurysms: A Life Threatening Case of Segmental Arterial Mediolysis.

    Cheng, Ernest M / Chen, Kerry L / Sharma, Varsha / Yee, Juliana / Power, Mark / Lemech, Lubomyr D / Chu, Francis

    Annals of vascular diseases

    2021  Volume 14, Issue 3, Page(s) 256–259

    Abstract: We present a 62-year-old gentleman with rapidly forming abdominal pseudoaneurysms due to segmental arterial mediolysis (SAM). With rupture of his pseudoaneurysms, he underwent angiography and successful coil embolisation. In this case, we demonstrate the ...

    Abstract We present a 62-year-old gentleman with rapidly forming abdominal pseudoaneurysms due to segmental arterial mediolysis (SAM). With rupture of his pseudoaneurysms, he underwent angiography and successful coil embolisation. In this case, we demonstrate the potential for rapid progression of pseudoaneurysms in SAM, with the need for prompt diagnosis and urgent endovascular intervention.
    Language English
    Publishing date 2021-08-18
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2394256-3
    ISSN 1881-6428 ; 1881-641X
    ISSN (online) 1881-6428
    ISSN 1881-641X
    DOI 10.3400/avd.cr.20-00172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease.

    Kolic, Jelena / Sun, WenQing Grace / Cen, Haoning Howard / Ewald, Jessica / Rogalski, Jason C / Sasaki, Shugo / Sun, Han / Rajesh, Varsha / Xia, Yi Han / Moravcova, Renata / Skovsø, Søs / Spigelman, Aliya F / Manning Fox, Jocelyn E / Lyon, James / Beet, Leanne / Xia, Jianguo / Lynn, Francis C / Gloyn, Anna L / Foster, Leonard J /
    MacDonald, Patrick E / Johnson, James D

    medRxiv : the preprint server for health sciences

    2024  

    Abstract: Population level variation and molecular mechanisms behind insulin secretion in response to carbohydrate, protein, and fat remain uncharacterized despite ramifications for personalized nutrition. Here, we define prototypical insulin secretion dynamics in ...

    Abstract Population level variation and molecular mechanisms behind insulin secretion in response to carbohydrate, protein, and fat remain uncharacterized despite ramifications for personalized nutrition. Here, we define prototypical insulin secretion dynamics in response to the three macronutrients in islets from 140 cadaveric donors, including those diagnosed with type 2 diabetes. While islets from the majority of donors exhibited the expected relative response magnitudes, with glucose being highest, amino acid moderate, and fatty acid small, 9% of islets stimulated with amino acid and 8% of islets stimulated with fatty acids had larger responses compared with high glucose. We leveraged this insulin response heterogeneity and used transcriptomics and proteomics to identify molecular correlates of specific nutrient responsiveness, as well as those proteins and mRNAs altered in type 2 diabetes. We also examine nutrient-responsiveness in stem cell-derived islet clusters and observe that they have dysregulated fuel sensitivity, which is a hallmark of functionally immature cells. Our study now represents the first comparison of dynamic responses to nutrients and multi-omics analysis in human insulin secreting cells. Responses of different people's islets to carbohydrate, protein, and fat lay the groundwork for personalized nutrition.
    One-sentence summary: Deep phenotyping and multi-omics reveal individualized nutrient-specific insulin secretion propensity.
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.05.24.23290298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: External quality assessment of COVID-19 real time reverse transcription PCR laboratories in India

    Harmanmeet Kaur / Labanya Mukhopadhyay / Nivedita Gupta / Neeraj Aggarwal / Lucky Sangal / Varsha Potdar / Francis Yesuraj Inbanathan / Jitendra Narayan / Swati Gupta / Salaj Rana / Neetu Vijay / Harpreet Singh / Jasmine Kaur / Vinit Kumar / Nirmal Kaundal / Priya Abraham / Vasanthapuram Ravi

    PLoS ONE, Vol 17, Iss

    2022  Volume 2

    Abstract: Sudden emergence and rapid spread of COVID-19 created an inevitable need for expansion of the COVID-19 laboratory testing network across the world. The strategy to test-track-treat was advocated for quick detection and containment of the disease. Being ... ...

    Abstract Sudden emergence and rapid spread of COVID-19 created an inevitable need for expansion of the COVID-19 laboratory testing network across the world. The strategy to test-track-treat was advocated for quick detection and containment of the disease. Being the second most populous country in the world, India was challenged to make COVID-19 testing available and accessible in all parts of the country. The molecular laboratory testing network was augmented expeditiously, and number of laboratories was increased from one in January 2020 to 2951 till mid-September, 2021. This rapid expansion warranted the need to have inbuilt systems of quality control/ quality assurance. In addition to the ongoing inter-laboratory quality control (ILQC), India implemented an External Quality Assurance Program (EQAP) with assistance from World Health Organization (WHO) and Royal College of Pathologists, Australasia. Out of the 953 open system rRTPCR laboratories in both public and private sector who participated in the first round of EQAP, 891(93.4%) laboratories obtained a passing score of > = 80%. The satisfactory performance of Indian COVID-19 testing laboratories has boosted the confidence of the public and policy makers in the quality of testing. ILQC and EQAP need to continue to ensure adherence of the testing laboratories to the desired quality standards.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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