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  1. Book ; Online ; E-Book: Wearable/personal monitoring devices present to future

    Gargiulo, Gaetano D. / Naik, Ganesh R.

    2022  

    Author's details edited by Gaetano D. Gargiulo, Ganesh R. Naik
    Keywords Wearable technology
    Subject code 002
    Language English
    Size 1 online resource (298 pages)
    Publisher Springer
    Publishing place Singapore
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 981-16-5324-0 ; 981-16-5323-2 ; 978-981-16-5324-7 ; 978-981-16-5323-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Applied Biomedical Engineering

    Gargiulo, Gaetano D / McEwan, Alistair

    2011  

    Keywords Biotechnology
    Language English
    Size 1 electronic resource (514 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030644849
    ISBN 9789535144540 ; 9535144545
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book ; Online: Advanced Biomedical Engineering

    Gargiulo, Gaetano D / McEwan, Alistair

    2011  

    Keywords Medical bioinformatics ; Medical ethics & professional conduct
    Language English
    Size 1 electronic resource (292 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English
    HBZ-ID HT030646704
    ISBN 9789535144533 ; 9535144537
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Arterial and venous peripheral vascular assessment using wearable electro-resistive morphic sensors.

    Varaki, Elham Shabani / Gargiulo, Gaetano D / Malone, Matthew / Breen, Paul P

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 1327

    Abstract: Peripheral vascular diseases (PVDs) represent a significant burden on global human health and healthcare systems. With continued growth in obesity and diabetes, it is likely that the incidence of these conditions will increase. As many PVDs remain ... ...

    Abstract Peripheral vascular diseases (PVDs) represent a significant burden on global human health and healthcare systems. With continued growth in obesity and diabetes, it is likely that the incidence of these conditions will increase. As many PVDs remain undiagnosed, low-cost and easy to use diagnostic methods are required. This work uses newly developed wearable electro-resistive morphic sensors to assess venous and arterial competence in the lower limbs of 36 healthy subjects. Comparison of this HeMo device was made to currently available benchtop light reflection rheography and photoplethymography devices. Results indicate that HeMo can detect the physiological signals of interest for both chronic venous insufficiency and peripheral arterial disease and all subjects were interpreted as healthy by each system. However, measurement repeatability of HeMo was highlighted as an issue that requires further system development. Furthermore, as HeMo captures changes in a section of limb circumference due to changes in underlying blood movement, rather than at a single point, the recorded signal is typically damped by comparison. This factor should be considered in any future developments.
    MeSH term(s) Humans ; Venous Insufficiency/diagnosis ; Veins ; Lower Extremity ; Peripheral Arterial Disease/diagnosis ; Wearable Electronic Devices
    Language English
    Publishing date 2024-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-50534-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Combined Cardiac and Respiratory Monitoring from a Single Signal: A Case Study Employing the Fantasia Database.

    Brandwood, Benjamin M / Naik, Ganesh R / Gunawardana, Upul / Gargiulo, Gaetano D

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 17

    Abstract: This study proposes a novel method for obtaining the electrocardiogram (ECG) derived respiration (EDR) from a single lead ECG and respiration-derived cardiogram (RDC) from a respiratory stretch sensor. The research aims to reconstruct the respiration ... ...

    Abstract This study proposes a novel method for obtaining the electrocardiogram (ECG) derived respiration (EDR) from a single lead ECG and respiration-derived cardiogram (RDC) from a respiratory stretch sensor. The research aims to reconstruct the respiration waveform, determine the respiration rate from ECG QRS heartbeat complexes data, locate heartbeats, and calculate a heart rate (HR) using the respiration signal. The accuracy of both methods will be evaluated by comparing located QRS complexes and inspiration maxima to reference positions. The findings of this study will ultimately contribute to the development of new, more accurate, and efficient methods for identifying heartbeats in respiratory signals, leading to better diagnosis and management of cardiovascular diseases, particularly during sleep where respiration monitoring is paramount to detect apnoea and other respiratory dysfunctions linked to a decreased life quality and known cause of cardiovascular diseases. Additionally, this work could potentially assist in determining the feasibility of using simple, no-contact wearable devices for obtaining simultaneous cardiology and respiratory data from a single device.
    MeSH term(s) Humans ; Cardiovascular Diseases/diagnosis ; Heart ; Electrocardiography ; Respiration ; Respiratory Rate
    Language English
    Publishing date 2023-08-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23177401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Changes in Forcecardiography Heartbeat Morphology Induced by Cardio-Respiratory Interactions.

    Centracchio, Jessica / Esposito, Daniele / Gargiulo, Gaetano D / Andreozzi, Emilio

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 23

    Abstract: The cardiac function is influenced by respiration. In particular, various parameters such as cardiac time intervals and the stroke volume are modulated by respiratory activity. It has long been recognized that cardio-respiratory interactions modify the ... ...

    Abstract The cardiac function is influenced by respiration. In particular, various parameters such as cardiac time intervals and the stroke volume are modulated by respiratory activity. It has long been recognized that cardio-respiratory interactions modify the morphology of cardio-mechanical signals, e.g., phonocardiogram, seismocardiogram (SCG), and ballistocardiogram. Forcecardiography (FCG) records the weak forces induced on the chest wall by the mechanical activity of the heart and lungs and relies on specific force sensors that are capable of monitoring respiration, infrasonic cardiac vibrations, and heart sounds, all simultaneously from a single site on the chest. This study addressed the changes in FCG heartbeat morphology caused by respiration. Two respiratory-modulated parameters were considered, namely the left ventricular ejection time (LVET) and a morphological similarity index (MSi) between heartbeats. The time trends of these parameters were extracted from FCG signals and further analyzed to evaluate their consistency within the respiratory cycle in order to assess their relationship with the breathing activity. The respiratory acts were localized in the time trends of the LVET and MSi and compared with a reference respiratory signal by computing the sensitivity and positive predictive value (PPV). In addition, the agreement between the inter-breath intervals estimated from the LVET and MSi and those estimated from the reference respiratory signal was assessed via linear regression and Bland-Altman analyses. The results of this study clearly showed a tight relationship between the respiratory activity and the considered respiratory-modulated parameters. Both the LVET and MSi exhibited cyclic time trends that remarkably matched the reference respiratory signal. In addition, they achieved a very high sensitivity and PPV (LVET: 94.7% and 95.7%, respectively; MSi: 99.3% and 95.3%, respectively). The linear regression analysis reported almost unit slopes for both the LVET (R
    Language English
    Publishing date 2022-11-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22239339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Respiratory-Induced Amplitude Modulation of Forcecardiography Signals.

    Centracchio, Jessica / Andreozzi, Emilio / Esposito, Daniele / Gargiulo, Gaetano D

    Bioengineering (Basel, Switzerland)

    2022  Volume 9, Issue 9

    Abstract: Forcecardiography (FCG) is a novel technique that records the weak forces induced on the chest wall by cardio-respiratory activity, by using specific force sensors. FCG sensors feature a wide frequency band, which allows us to capture respiration, heart ... ...

    Abstract Forcecardiography (FCG) is a novel technique that records the weak forces induced on the chest wall by cardio-respiratory activity, by using specific force sensors. FCG sensors feature a wide frequency band, which allows us to capture respiration, heart wall motion, heart valves opening and closing (similar to the Seismocardiogram, SCG) and heart sounds, all simultaneously from a single contact point on the chest. As a result, the raw FCG sensors signals exhibit a large component related to the respiratory activity, referred to as a Forcerespirogram (FRG), with a much smaller, superimposed component related to the cardiac activity (the actual FCG) that contains both infrasonic vibrations, referred to as LF-FCG and HF-FCG, and heart sounds. Although respiration can be readily monitored by extracting the very low-frequency component of the raw FCG signal (FRG), it has been observed that the respiratory activity also influences other FCG components, particularly causing amplitude modulations (AM). This preliminary study aimed to assess the consistency of the amplitude modulations of the LF-FCG and HF-FCG signals within the respiratory cycle. A retrospective analysis was performed on the FCG signals acquired in a previous study on six healthy subjects at rest, during quiet breathing. To this aim, the AM of LF-FCG and HF-FCG were first extracted via a linear envelope (LE) operation, consisting of rectification followed by low-pass filtering; then, the inspiratory peaks were located both in the LE of LF-FCG and HF-FCG, and in the reference respiratory signal (FRG). Finally, the inter-breath intervals were extracted from the obtained inspiratory peaks, and further analyzed via statistical analyses. The AM of HF-FCG exhibited higher consistency within the respiratory cycle, as compared to the LF-FCG. Indeed, the inspiratory peaks were recognized with a sensitivity and positive predictive value (PPV) in excess of 99% in the LE of HF-FCG, and with a sensitivity and PPV of 96.7% and 92.6%, respectively, in the LE of LF-FCG. In addition, the inter-breath intervals estimated from the HF-FCG scored a higher R
    Language English
    Publishing date 2022-09-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering9090444
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Electrodeless Heart and Respiratory Rate Estimation during Sleep Using a Single Fabric Band and Event-Based Edge Processing.

    Jayarathna, Titus / Gargiulo, Gaetano D / Lui, Gough Y / Breen, Paul P

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 17

    Abstract: Heart rate (HR) and respiratory rate (RR) are two vital parameters of the body medically used for diagnosing short/long-term illness. Out-of-the-body, non-skin-contact HR/RR measurement remains a challenge due to imprecise readings. "Invisible" wearables ...

    Abstract Heart rate (HR) and respiratory rate (RR) are two vital parameters of the body medically used for diagnosing short/long-term illness. Out-of-the-body, non-skin-contact HR/RR measurement remains a challenge due to imprecise readings. "Invisible" wearables integrated into day-to-day garments have the potential to produce precise readings with a comfortable user experience. Sleep studies and patient monitoring benefit from "Invisibles" due to longer wearability without significant discomfort. This paper suggests a novel method to reduce the footprint of sleep monitoring devices. We use a single silver-coated nylon fabric band integrated into a substrate of a standard cotton/nylon garment as a resistive elastomer sensor to measure air and blood volume change across the chest. We introduce a novel event-based architecture to process data at the edge device and describe two algorithms to calculate real-time HR/RR on ARM Cortex-M3 and Cortex-M4F microcontrollers. RR estimations show a sensitivity of 99.03% and a precision of 99.03% for identifying individual respiratory peaks. The two algorithms used for HR calculation show a mean absolute error of 0.81 ± 0.97 and 0.86±0.61 beats/min compared with a gold standard ECG-based HR. The event-based algorithm converts the respiratory/pulse waveform into instantaneous events, therefore reducing the data size by 40-140 times and requiring 33% less power to process and transfer data. Furthermore, we show that events hold enough information to reconstruct the original waveform, retaining pulse and respiratory activity. We suggest fabric sensors and event-based algorithms would drastically reduce the device footprint and increase the performance for HR/RR estimations during sleep studies, providing a better user experience.
    MeSH term(s) Heart Rate/physiology ; Humans ; Nylons ; Polysomnography ; Respiratory Rate/physiology ; Sleep
    Chemical Substances Nylons
    Language English
    Publishing date 2022-09-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22176689
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: True unipolar ECG machine for Wilson Central Terminal measurements.

    Gargiulo, Gaetano D

    BioMed research international

    2015  Volume 2015, Page(s) 586397

    Abstract: Since its invention (more than 80 years ago), modern electrocardiography has employed a supposedly stable voltage reference (with little variation during the cardiac cycle) for half of the signals. This reference, known by the name of "Wilson Central ... ...

    Abstract Since its invention (more than 80 years ago), modern electrocardiography has employed a supposedly stable voltage reference (with little variation during the cardiac cycle) for half of the signals. This reference, known by the name of "Wilson Central Terminal" in honor of its inventor, is obtained by averaging the three active limb electrode voltages measured with respect to the return ground electrode. However, concerns have been raised by researchers about problems (biasing and misdiagnosis) associated with the ambiguous value and behavior of this reference voltage, which requires perfect and balanced contact of at least four electrodes to work properly. The Wilson Central Terminal has received scant research attention in the last few decades even though consideration of recent widespread medical practice (limb electrodes are repositioned closer to the torso for resting electrocardiography) has also sparkled concerns about the validity and diagnostic fitness of leads not referred to the Wilson Central Terminal. Using a true unipolar electrocardiography device capable of precisely measuring the Wilson Central Terminal, we show its unpredictable variability during the cardiac cycle and confirm that the integrity of cardinal leads is compromised as well as the Wilson Central Terminal when limb electrodes are placed close to the torso.
    MeSH term(s) Adult ; Body Surface Potential Mapping/instrumentation ; Computer Simulation ; Electrocardiography/instrumentation ; Electrocardiography/methods ; Electrodes ; Equipment Design ; Equipment Failure Analysis ; Female ; Heart Rate/physiology ; Humans ; Male ; Models, Cardiovascular ; Pilot Projects ; Reproducibility of Results ; Sensitivity and Specificity
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2015/586397
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: A Novel Broadband Forcecardiography Sensor for Simultaneous Monitoring of Respiration, Infrasonic Cardiac Vibrations and Heart Sounds.

    Andreozzi, Emilio / Gargiulo, Gaetano D / Esposito, Daniele / Bifulco, Paolo

    Frontiers in physiology

    2021  Volume 12, Page(s) 725716

    Abstract: The precordial mechanical vibrations generated by cardiac contractions have a rich frequency spectrum. While the lowest frequencies can be palpated, the higher infrasonic frequencies are usually captured by the seismocardiogram (SCG) signal and the ... ...

    Abstract The precordial mechanical vibrations generated by cardiac contractions have a rich frequency spectrum. While the lowest frequencies can be palpated, the higher infrasonic frequencies are usually captured by the seismocardiogram (SCG) signal and the audible ones correspond to heart sounds. Forcecardiography (FCG) is a non-invasive technique that measures these vibrations via force sensing resistors (FSR). This study presents a new piezoelectric sensor able to record all heart vibrations simultaneously, as well as a respiration signal. The new sensor was compared to the FSR-based one to assess its suitability for FCG. An electrocardiogram (ECG) lead and a signal from an electro-resistive respiration band (ERB) were synchronously acquired as references on six healthy volunteers (4 males, 2 females) at rest. The raw signals from the piezoelectric and the FSR-based sensors turned out to be very similar. The raw signals were divided into four components: Forcerespirogram (FRG), Low-Frequency FCG (LF-FCG), High-Frequency FCG (HF-FCG) and heart sounds (HS-FCG). A beat-by-beat comparison of FCG and ECG signals was carried out by means of regression, correlation and Bland-Altman analyses, and similarly for respiration signals (FRG and ERB). The results showed that the infrasonic FCG components are strongly related to the cardiac cycle (
    Language English
    Publishing date 2021-11-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2021.725716
    Database MEDical Literature Analysis and Retrieval System OnLINE

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