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Article: E

Shifman, Aaron R / Lewis, John E

2019 Volume 13, Page(s) 35

Abstract: The transmembrane ionic currents that underlie changes in a cell's membrane potential give rise to electric fields in the extracellular space. In the context of brain activity, these electric fields form the basis for extracellularly recorded signals, ... ...

Abstract	The transmembrane ionic currents that underlie changes in a cell's membrane potential give rise to electric fields in the extracellular space. In the context of brain activity, these electric fields form the basis for extracellularly recorded signals, such as multiunit activity, local field potentials and electroencephalograms. Understanding the underlying neuronal dynamics and localizing current sources using these signals is often challenging, and therefore effective computational modeling approaches are critical. Typically, the electric fields from neural activity are modeled in a
Language	English
Publishing date	2019-05-31
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2452979-5
ISSN	1662-5196
ISSN	1662-5196
DOI	10.3389/fninf.2019.00035
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Article ; Online: Safety of e-cigarettes and nicotine patches as stop-smoking aids in pregnancy: Secondary analysis of the Pregnancy Trial of E-cigarettes and Patches (PREP) randomized controlled trial.

Addiction (Abingdon, England)

2024 Volume 119, Issue 5, Page(s) 875–884

Abstract: Aims: The aim of this study was to examine the safety of e-cigarettes (EC) and nicotine patches ... status. EC or NRT use had no association with relapse.: Conclusions: Regular use of e-cigarettes or ...

Abstract	Aims: The aim of this study was to examine the safety of e-cigarettes (EC) and nicotine patches (NRT) when used to help pregnant smokers quit. Design: A recent trial of EC versus NRT reported safety outcomes in the randomized arms. We conducted a further analysis based on product use. Setting: Twenty-three hospitals in England and a stop-smoking service in Scotland took part. Participants: The participants comprised 1140 pregnant smokers. Interventions: We compared women using and not using EC and NRT regularly during pregnancy. Measurements: Measurements included nicotine intake compared with baseline, birth weight, other pregnancy outcomes, adverse events, maternal respiratory symptoms and relapse in early abstainers. Findings: Use of EC was more common than use of NRT (47.3% vs 21.6%, P < 0.001). Women who stopped smoking (abstainers) and used EC at the end-of-pregnancy (EOP) reduced their salivary cotinine by 45% [49.3 ng/ml, 95% confidence interval (CI) = -79.8 to -10]. Only one abstainer used NRT at EOP. In dual users, cotinine increased by 19% (24 ng/ml, 95% CI = 3.5-68). In women reporting a reduction of at least 50% in cigarette consumption, cotinine levels increased by 10% in those using nicotine products and by 9% in those who did not. Birth weights in dual users and exclusive smokers were the same (3.1 kg). Birth weight in abstainers using either nicotine product was higher than in smokers [3.3 kg, standard deviation (SD) = 0.7] versus 3.1 kg, SD = 0.6; difference = 0.15 kg, 95% CI = 0.05-0.25) and not different from abstainers not using nicotine products (3.1 kg, SD = 0.8). Abstainers and smokers using nicotine products had no worse pregnancy outcomes or more adverse events than abstainers and smokers not using them. EC users reported more improvements than non-users in cough [adjusted relative risk (aRR) = 0.59, 95% CI = 0.37-0.93] and phlegm (aRR = 0.53, 95% CI = 0.31-0.92), controlling for smoking status. EC or NRT use had no association with relapse. Conclusions: Regular use of e-cigarettes or nicotine patches by pregnant smokers does not appear to be associated with any adverse outcomes.
MeSH term(s)	Pregnancy ; Female ; Humans ; Nicotine ; Cotinine ; Electronic Nicotine Delivery Systems ; Smoking Cessation ; Birth Weight ; Smoking/adverse effects ; Recurrence
Chemical Substances	Nicotine (6M3C89ZY6R) ; Cotinine (K5161X06LL)
Language	English
Publishing date	2024-01-17
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1141051-6
ISSN	1360-0443 ; 0965-2140
ISSN (online)	1360-0443
ISSN	0965-2140
DOI	10.1111/add.16422
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Article ; Online: Prostaglandin E

Heffner, Garrett C / Bonner, Melissa / Christiansen, Lauryn / Pierciey, Francis J / Campbell, Dakota / Smurnyy, Yegor / Zhang, Wenliang / Hamel, Amanda / Shaw, Seema / Lewis, Gretchen / Goss, Kendrick A / Garijo, Olivia / Torbett, Bruce E / Horton, Holly / Finer, Mitchell H / Gregory, Philip D / Veres, Gabor

Molecular therapy : the journal of the American Society of Gene Therapy

2017 Volume 26, Issue 1, Page(s) 320–328

Abstract: Gene therapy currently in development for hemoglobinopathies utilizes ex vivo lentiviral transduction of ... ...

Abstract	Gene therapy currently in development for hemoglobinopathies utilizes ex vivo lentiviral transduction of CD34
MeSH term(s)	Anemia, Sickle Cell/genetics ; Anemia, Sickle Cell/metabolism ; Animals ; Antigens, CD34/metabolism ; Cell Line ; Dinoprostone/metabolism ; Gene Library ; Gene Transfer Techniques ; Genetic Therapy ; Genetic Vectors/genetics ; Globins/genetics ; Hematopoietic Stem Cells/metabolism ; Humans ; Lentivirus/genetics ; Leukocyte Common Antigens/metabolism ; Mice ; Transduction, Genetic ; Transgenes ; Transplantation, Heterologous ; Virus Internalization ; beta-Thalassemia/genetics ; beta-Thalassemia/metabolism
Chemical Substances	Antigens, CD34 ; Globins (9004-22-2) ; Leukocyte Common Antigens (EC 3.1.3.48) ; Dinoprostone (K7Q1JQR04M)
Language	English
Publishing date	2017-10-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2010592-7
ISSN	1525-0024 ; 1525-0016
ISSN (online)	1525-0024
ISSN	1525-0016
DOI	10.1016/j.ymthe.2017.09.025
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Article ; Online: Search for the Lepton Flavor Violating Decays B^{+}→K^{+}τ^{±}ℓ^{∓} (ℓ=e, μ) at Belle.

Watanuki, S / de Marino, G / Trabelsi, K / Adachi, I / Aihara, H / Asner, D M / Atmacan, H / Aulchenko, V / Aushev, T / Ayad, R / Babu, V / Banerjee, Sw / Bauer, M / Behera, P / Belous, K / Bessner, M / Bhardwaj, V / Bhuyan, B / Biswas, D /

Bodrov, D / Bonvicini, G / Borah, J / Bozek, A / Bračko, M / Branchini, P / Browder, T E / Budano, A / Campajola, M / Cao, L / Červenkov, D / Chang, M-C / Cheon, B G / Chilikin, K / Cho, K / Cho, S-J / Choi, S-K / Choi, Y / Choudhury, S / Cinabro, D / Das, S / De Nardo, G / De Pietro, G / Dhamija, R / Di Capua, F / Dong, T V / Epifanov, D / Ferber, T / Ferlewicz, D / Fulsom, B G / Garg, R / Gaur, V / Garmash, A / Giri, A / Goldenzweig, P / Graziani, E / Gu, T / Guan, Y / Gudkova, K / Hadjivasiliou, C / Halder, S / Han, X / Hara, T / Hayasaka, K / Hayashii, H / Herrmann, D / Hou, W-S / Hsu, C-L / Inami, K / Inguglia, G / Ipsita, N / Ishikawa, A / Itoh, R / Iwasaki, M / Jacobs, W W / Ji, Q P / Jia, S / Jin, Y / Joo, K K / Kaliyar, A B / Kichimi, H / Kim, C H / Kim, D Y / Kim, K-H / Kim, Y-K / Kinoshita, K / Kodyš, P / Korobov, A / Korpar, S / Kovalenko, E / Križan, P / Krokovny, P / Kuhr, T / Kumar, M / Kumara, K / Kuzmin, A / Kwon, Y-J / Lange, J S / Laurenza, M / Lee, S C / Lewis, P / Li, L K / Li, Y / Li Gioi, L / Libby, J / Lin, Y-R / Liventsev, D / Matsuda, T / Maurya, S K / Meier, F / Merola, M / Metzner, F / Miyabayashi, K / Mizuk, R / Mohanty, G B / Nakao, M / Nayak, L / Nayak, M / Nisar, N K / Nishida, S / Ono, H / Oskin, P / Pakhlova, G / Pardi, S / Park, H / Park, J / Park, S-H / Passeri, A / Pedlar, T K / Pestotnik, R / Piilonen, L E / Podobnik, T / Prencipe, E / Prim, M T / Röhrken, M / Rout, N / Russo, G / Sandilya, S / Sangal, A / Santelj, L / Savinov, V / Schnell, G / Schwanda, C / Seino, Y / Senyo, K / Sevior, M E / Shan, W / Shapkin, M / Shiu, J-G / Shwartz, B / Simon, F / Solovieva, E / Starič, M / Sumihama, M / Sumiyoshi, T / Takizawa, M / Tanida, K / Tenchini, F / Uchida, M / Uglov, T / Unno, Y / Uno, K / Uno, S / van Tonder, R / Varner, G / Varvell, K E / Wang, D / Wang, E / Wang, M-Z / Won, E / Xu, X / Yabsley, B D / Yan, W / Yang, S B / Yelton, J / Yusa, Y / Zhang, Z P / Zhilich, V / Zhukova, V

Physical review letters

2023 Volume 130, Issue 26, Page(s) 261802

Abstract: We present a search for the lepton flavor violating decays B^{+}→K^{+}τ^{±}ℓ^{∓}, with ℓ=(e,μ ... asymmetric-energy e^{+}e^{-} collider. We use events in which one B meson is fully reconstructed ...

Abstract	We present a search for the lepton flavor violating decays B^{+}→K^{+}τ^{±}ℓ^{∓}, with ℓ=(e,μ), using the full data sample of 772×10^{6} BB[over ¯] pairs recorded by the Belle detector at the KEKB asymmetric-energy e^{+}e^{-} collider. We use events in which one B meson is fully reconstructed in a hadronic decay mode. We find no evidence for B^{±}→K^{±}τℓ decays and set upper limits on their branching fractions at the 90% confidence level in the (1-3)×10^{-5} range. The obtained limits are the world's best results.
Language	English
Publishing date	2023-01-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.130.261802
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Article ; Online: Search for a τ^{+}τ^{-} Resonance in e^{+}e^{-}→μ^{+}μ^{-}τ^{+}τ^{-} Events with the Belle II Experiment.

Adachi, I / Adamczyk, K / Aggarwal, L / Ahmed, H / Aihara, H / Akopov, N / Aloisio, A / Anh Ky, N / Asner, D M / Atmacan, H / Aushev, T / Aushev, V / Aversano, M / Babu, V / Bae, H / Bahinipati, S / Bambade, P / Banerjee, Sw / Bansal, S /

Barrett, M / Baudot, J / Bauer, M / Baur, A / Beaubien, A / Becker, J / Behera, P K / Bennett, J V / Bernieri, E / Bernlochner, F U / Bertacchi, V / Bertemes, M / Bertholet, E / Bessner, M / Bettarini, S / Bhardwaj, V / Bhuyan, B / Bianchi, F / Bilka, T / Bilokin, S / Biswas, D / Bobrov, A / Bodrov, D / Bolz, A / Borah, J / Bozek, A / Bračko, M / Branchini, P / Browder, T E / Budano, A / Bussino, S / Campajola, M / Cao, L / Casarosa, G / Cecchi, C / Cerasoli, J / Chang, M-C / Chang, P / Cheaib, R / Cheema, P / Chekelian, V / Chen, Y Q / Cheon, B G / Chilikin, K / Chirapatpimol, K / Cho, H-E / Cho, K / Cho, S-J / Choi, S-K / Choudhury, S / Cinabro, D / Cochran, J / Corona, L / Cremaldi, L M / Cunliffe, S / Czank, T / Das, S / Dattola, F / De La Cruz-Burelo, E / De La Motte, S A / de Marino, G / De Nardo, G / De Nuccio, M / De Pietro, G / de Sangro, R / Destefanis, M / Dey, S / De Yta-Hernandez, A / Dhamija, R / Di Canto, A / Di Capua, F / Dingfelder, J / Doležal, Z / Domínguez Jiménez, I / Dong, T V / Dorigo, M / Dort, K / Dossett, D / Dreyer, S / Dubey, S / Dujany, G / Ecker, P / Eliachevitch, M / Epifanov, D / Feichtinger, P / Ferber, T / Ferlewicz, D / Fillinger, T / Finck, C / Finocchiaro, G / Fodor, A / Forti, F / Frey, A / Fulsom, B G / Gabrielli, A / Ganiev, E / Garcia-Hernandez, M / Garmash, A / Gaudino, G / Gaur, V / Gaz, A / Gellrich, A / Ghevondyan, G / Ghosh, D / Ghumaryan, H / Giakoustidis, G / Giordano, R / Giri, A / Glazov, A / Gobbo, B / Godang, R / Gogota, O / Goldenzweig, P / Gradl, W / Grammatico, T / Granderath, S / Graziani, E / Greenwald, D / Gruberová, Z / Gu, T / Guan, Y / Gudkova, K / Guilliams, J / Halder, S / Han, Y / Hara, T / Hayasaka, K / Hayashii, H / Hazra, S / Hearty, C / Hedges, M T / Heredia de la Cruz, I / Hernández Villanueva, M / Hershenhorn, A / Higuchi, T / Hill, E C / Hirata, H / Hoek, M / Hohmann, M / Hsu, C-L / Humair, T / Iijima, T / Inami, K / Inguglia, G / Ipsita, N / Ishikawa, A / Ito, S / Itoh, R / Iwasaki, M / Jackson, P / Jacobs, W W / Jaffe, D E / Jang, E-J / Ji, Q P / Jia, S / Jin, Y / Johnson, A / Joo, K K / Junkerkalefeld, H / Kakuno, H / Kaleta, M / Kalita, D / Kaliyar, A B / Kandra, J / Kang, K H / Kang, S / Karl, R / Karyan, G / Kawasaki, T / Keil, F / Ketter, C / Kiesling, C / Kim, C-H / Kim, D Y / Kim, K-H / Kim, Y-K / Kindo, H / Kodyš, P / Koga, T / Kohani, S / Kojima, K / Konno, T / Korobov, A / Korpar, S / Kovalenko, E / Kowalewski, R / Kraetzschmar, T M G / Križan, P / Krokovny, P / Kuhr, T / Kumar, J / Kumar, M / Kumar, R / Kumara, K / Kunigo, T / Kuzmin, A / Kwon, Y-J / Lacaprara, S / Lai, Y-T / Lam, T / Lanceri, L / Lange, J S / Laurenza, M / Lautenbach, K / Leboucher, R / Le Diberder, F R / Leitl, P / Levit, D / Lewis, P M / Li, C / Li, L K / Li, Y B / Libby, J / Lieret, K / Liu, Q Y / Liu, Z Q / Liventsev, D / Longo, S / Lozar, A / Lueck, T / Lyu, C / Ma, Y / Maggiora, M / Maharana, S P / Maiti, R / Maity, S / Manfredi, R / Manoni, E / Manthei, A C / Mantovano, M / Marcantonio, D / Marcello, S / Marinas, C / Martel, L / Martellini, C / Martini, A / Martinov, T / Massaccesi, L / Masuda, M / Matsuda, T / Matsuoka, K / Matvienko, D / Maurya, S K / McKenna, J A / Mehta, R / Merola, M / Metzner, F / Milesi, M / Miller, C / Mirra, M / Miyabayashi, K / Miyake, H / Mizuk, R / Mohanty, G B / Molina-Gonzalez, N / Mondal, S / Moneta, S / Moser, H-G / Mrvar, M / Mussa, R / Nakamura, I / Nakamura, K R / Nakao, M / Nakayama, H / Nakazawa, H / Nakazawa, Y / Narimani Charan, A / Naruki, M / Narwal, D / Natkaniec, Z / Natochii, A / Nayak, L / Nayak, M / Nazaryan, G / Niebuhr, C / Nisar, N K / Nishida, S / Ogawa, S / Ono, H / Onuki, Y / Oskin, P / Otani, F / Pakhlov, P / Pakhlova, G / Paladino, A / Panta, A / Paoloni, E / Pardi, S / Parham, K / Park, J / Park, S-H / Paschen, B / Passeri, A / Patra, S / Paul, S / Pedlar, T K / Peruzzi, I / Peschke, R / Pestotnik, R / Pham, F / Piccolo, M / Piilonen, L E / Pinna Angioni, G / Podesta-Lerma, P L M / Podobnik, T / Pokharel, S / Polat, L / Praz, C / Prell, S / Prencipe, E / Prim, M T / Purwar, H / Rad, N / Rados, P / Raeuber, G / Raiz, S / Ramirez Morales, A / Reif, M / Reiter, S / Remnev, M / Ripp-Baudot, I / Rizzo, G / Rizzuto, L B / Robertson, S H / Rodríguez Pérez, D / Roehrken, M / Roney, J M / Rostomyan, A / Rout, N / Russo, G / Sahoo, D / Sanders, D A / Sandilya, S / Sangal, A / Santelj, L / Sato, Y / Savinov, V / Scavino, B / Schnepf, M / Schueler, J / Schwanda, C / Seino, Y / Selce, A / Senyo, K / Serrano, J / Sevior, M E / Sfienti, C / Shan, W / Sharma, C / Shen, C P / Shi, X D / Shillington, T / Shiu, J-G / Shtol, D / Shwartz, B / Sibidanov, A / Simon, F / Singh, J B / Skorupa, J / Sobie, R J / Sobotzik, M / Soffer, A / Sokolov, A / Solovieva, E / Spataro, S / Spruck, B / Starič, M / Stavroulakis, P / Stefkova, S / Stottler, Z S / Stroili, R / Strube, J / Sue, Y / Sumihama, M / Sumisawa, K / Sutcliffe, W / Suzuki, S Y / Svidras, H / Takahashi, M / Takizawa, M / Tamponi, U / Tanaka, S / Tanida, K / Tanigawa, H / Tenchini, F / Thaller, A / Tiwary, R / Tonelli, D / Torassa, E / Toutounji, N / Trabelsi, K / Tsaklidis, I / Uchida, M / Ueda, I / Uematsu, Y / Uglov, T / Unger, K / Unno, Y / Uno, K / Uno, S / Urquijo, P / Ushiroda, Y / Vahsen, S E / van Tonder, R / Varner, G S / Varvell, K E / Vinokurova, A / Vismaya, V S / Vitale, L / Vobbilisetti, V / Volpe, R / Vossen, A / Wach, B / Wakai, M / Wakeling, H M / Wallner, S / Wang, E / Wang, M-Z / Wang, X L / Wang, Z / Warburton, A / Watanabe, M / Watanuki, S / Welsch, M / Wessel, C / Won, E / Xu, X P / Yabsley, B D / Yamada, S / Yan, W / Yang, S B / Ye, H / Yelton, J / Yin, J H / Yook, Y M / Yoshihara, K / Yuan, C Z / Yusa, Y / Zani, L / Zhai, Y / Zhang, Y / Zhilich, V / Zhou, J S / Zhou, Q D / Zhou, X Y / Zhukova, V I / Žlebčík, R

Physical review letters

2023 Volume 131, Issue 12, Page(s) 121802

Abstract: We report the first search for a nonstandard-model resonance decaying into τ pairs in e^{+}e^{-}→μ^ ... μ^{-}τ^{+}τ^{-} events in the 3.6-10 GeV/c^{2} mass range. We use a 62.8 fb^{-1} sample of e^{+}e^ ...

Abstract	We report the first search for a nonstandard-model resonance decaying into τ pairs in e^{+}e^{-}→μ^{+}μ^{-}τ^{+}τ^{-} events in the 3.6-10 GeV/c^{2} mass range. We use a 62.8 fb^{-1} sample of e^{+}e^{-} collisions collected at a center-of-mass energy of 10.58 GeV by the Belle II experiment at the SuperKEKB collider. The analysis probes three different models predicting a spin-1 particle coupling only to the heavier lepton families, a Higgs-like spin-0 particle that couples preferentially to charged leptons (leptophilic scalar), and an axionlike particle, respectively. We observe no evidence for a signal and set exclusion limits at 90% confidence level on the product of cross section and branching fraction into τ pairs, ranging from 0.7 to 24 fb, and on the couplings of these processes. We obtain world-leading constraints on the couplings for the leptophilic scalar model for masses above 6.5 GeV/c^{2} and for the axionlike particle model over the entire mass range.
Language	English
Publishing date	2023-10-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.131.121802
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Article ; Online: Reply to A Drewnowski et al, O Devinsky, D A Booth and E L Gibson, and D J Millward.

Ludwig, David S / Aronne, Louis J / Astrup, Arne / de Cabo, Rafael / Cantley, Lewis C / Friedman, Mark I / Heymsfield, Steven B / Johnson, James D / King, Janet C / Krauss, Ronald M / Lieberman, Daniel E / Taubes, Gary / Volek, Jeff S / Westman, Eric C / Willett, Walter C / Yancy, William S / Ebbeling, Cara B

The American journal of clinical nutrition

2022 Volume 115, Issue 2, Page(s) 595–597

Language	English
Publishing date	2022-02-09
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	280048-2
ISSN	1938-3207 ; 0002-9165
ISSN (online)	1938-3207
ISSN	0002-9165
DOI	10.1093/ajcn/nqab385
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Article ; Online: Observation of e^{+}e^{-}→ωχ_{bJ}(1P) and Search for X_{b}→ωϒ(1S) at sqrt[s] near 10.75 GeV.

Adachi, I / Aggarwal, L / Ahmed, H / Aihara, H / Akopov, N / Aloisio, A / Anh Ky, N / Asner, D M / Aushev, T / Aushev, V / Bae, H / Bambade, P / Banerjee, Sw / Baudot, J / Bauer, M / Beaubien, A / Becker, J / Behera, P K / Bennett, J V /

Bernieri, E / Bernlochner, F U / Bertacchi, V / Bertemes, M / Bertholet, E / Bessner, M / Bettarini, S / Bhuyan, B / Bianchi, F / Bilka, T / Biswas, D / Bodrov, D / Bolz, A / Borah, J / Bozek, A / Bračko, M / Branchini, P / Browder, T E / Budano, A / Bussino, S / Campajola, M / Cao, L / Casarosa, G / Chang, M-C / Cheema, P / Chekelian, V / Chen, Y Q / Chilikin, K / Chirapatpimol, K / Cho, H-E / Cho, K / Cho, S-J / Choi, S-K / Choudhury, S / Cinabro, D / Corona, L / Cunliffe, S / Das, S / Dattola, F / De La Cruz-Burelo, E / De La Motte, S A / De Nardo, G / De Nuccio, M / De Pietro, G / de Sangro, R / Destefanis, M / Dey, S / De Yta-Hernandez, A / Dhamija, R / Di Canto, A / Di Capua, F / Doležal, Z / Domínguez Jiménez, I / Dong, T V / Dorigo, M / Dort, K / Dreyer, S / Dubey, S / Dujany, G / Eliachevitch, M / Feichtinger, P / Ferber, T / Ferlewicz, D / Fillinger, T / Finocchiaro, G / Fodor, A / Forti, F / Fulsom, B G / Ganiev, E / Gaur, V / Gaz, A / Gellrich, A / Ghevondyan, G / Giordano, R / Giri, A / Glazov, A / Gobbo, B / Godang, R / Goldenzweig, P / Granderath, S / Graziani, E / Greenwald, D / Gu, T / Guan, Y / Gudkova, K / Guilliams, J / Hara, T / Hayasaka, K / Hayashii, H / Hazra, S / Hearty, C / Heredia de la Cruz, I / Hernández Villanueva, M / Hershenhorn, A / Higuchi, T / Hill, E C / Hirata, H / Hohmann, M / Hsu, C-L / Iijima, T / Inami, K / Inguglia, G / Ipsita, N / Ishikawa, A / Ito, S / Iwasaki, M / Jackson, P / Jacobs, W W / Jaffe, D E / Jang, E-J / Ji, Q P / Jia, S / Jin, Y / Joo, K K / Junkerkalefeld, H / Kaliyar, A B / Kang, K H / Karl, R / Karyan, G / Ketter, C / Kiesling, C / Kim, C-H / Kim, D Y / Kim, K-H / Kim, Y-K / Kindo, H / Kodyš, P / Koga, T / Kohani, S / Kojima, K / Konno, T / Korobov, A / Korpar, S / Kovalenko, E / Kowalewski, R / Kraetzschmar, T M G / Križan, P / Krokovny, P / Kumar, R / Kumara, K / Kunigo, T / Kuzmin, A / Kwon, Y-J / Lacaprara, S / Lam, T / Lanceri, L / Lange, J S / Laurenza, M / Lautenbach, K / Leboucher, R / Lewis, P M / Li, C / Li, L K / Libby, J / Lieret, K / Liptak, Z / Liu, Q Y / Liventsev, D / Longo, S / Lozar, A / Lueck, T / Lyu, C / Maggiora, M / Maiti, R / Manfredi, R / Manoni, E / Marcello, S / Marinas, C / Martel, L / Martini, A / Martinov, T / Massaccesi, L / Masuda, M / Matsuoka, K / Maurya, S K / McKenna, J A / Merola, M / Metzner, F / Milesi, M / Miller, C / Miyabayashi, K / Mizuk, R / Molina-Gonzalez, N / Moneta, S / Moser, H-G / Mrvar, M / Mussa, R / Nakamura, I / Nakao, M / Nakazawa, Y / Narimani Charan, A / Naruki, M / Natkaniec, Z / Natochii, A / Nayak, L / Nayak, M / Nazaryan, G / Nisar, N K / Ogawa, S / Ono, H / Onuki, Y / Oskin, P / Paladino, A / Panta, A / Paoloni, E / Pardi, S / Park, H / Park, S-H / Paschen, B / Passeri, A / Paul, S / Pedlar, T K / Peruzzi, I / Peschke, R / Pestotnik, R / Piccolo, M / Piilonen, L E / Podesta-Lerma, P L M / Podobnik, T / Pokharel, S / Polat, L / Praz, C / Prell, S / Prencipe, E / Prim, M T / Purwar, H / Rad, N / Raiz, S / Ramirez Morales, A / Reif, M / Reiter, S / Remnev, M / Ripp-Baudot, I / Rizzo, G / Robertson, S H / Roney, J M / Rostomyan, A / Rout, N / Russo, G / Sanders, D A / Sandilya, S / Sangal, A / Santelj, L / Sato, Y / Savinov, V / Scavino, B / Schueler, J / Schwanda, C / Seino, Y / Selce, A / Senyo, K / Serrano, J / Sevior, M E / Sfienti, C / Shen, C P / Shi, X D / Shillington, T / Sibidanov, A / Singh, J B / Skorupa, J / Sobie, R J / Soffer, A / Solovieva, E / Spataro, S / Starič, M / Stefkova, S / Stottler, Z S / Stroili, R / Sue, Y / Sumihama, M / Sumisawa, K / Sutcliffe, W / Suzuki, S Y / Svidras, H / Takizawa, M / Tanida, K / Tanigawa, H / Tenchini, F / Thaller, A / Tiwary, R / Tonelli, D / Torassa, E / Toutounji, N / Trabelsi, K / Uchida, M / Ueda, I / Uematsu, Y / Uglov, T / Unger, K / Unno, Y / Uno, K / Uno, S / Ushiroda, Y / Vahsen, S E / van Tonder, R / Varner, G S / Vinokurova, A / Vitale, L / Vobbilisetti, V / Wakeling, H M / Wang, E / Wang, M-Z / Warburton, A / Watanuki, S / Welsch, M / Wessel, C / Won, E / Xu, X P / Yabsley, B D / Yamada, S / Yan, W / Yang, S B / Ye, H / Yelton, J / Yin, J H / Yook, Y M / Yoshihara, K / Yuan, C Z / Zani, L / Zhang, Y / Zhou, X Y / Zhukova, V I / Žlebčík, R

Physical review letters

2023 Volume 130, Issue 9, Page(s) 91902

Abstract: We study the processes e^{+}e^{-}→ωχ_{bJ}(1P) (J=0, 1, or 2) using samples at center-of-mass ... dependencies of the Born cross sections for e^{+}e^{-}→ωχ_{b1,b2}(1P) to be consistent with the shape of the ϒ ...

Abstract	We study the processes e^{+}e^{-}→ωχ_{bJ}(1P) (J=0, 1, or 2) using samples at center-of-mass energies sqrt[s]=10.701, 10.745, and 10.805 GeV, corresponding to 1.6, 9.8, and 4.7 fb^{-1} of integrated luminosity, respectively. These data were collected with the Belle II detector during special operations of the SuperKEKB collider above the ϒ(4S) resonance. We report the first observation of ωχ_{bJ}(1P) signals at sqrt[s]=10.745 GeV. By combining Belle II data with Belle results at sqrt[s]=10.867 GeV, we find energy dependencies of the Born cross sections for e^{+}e^{-}→ωχ_{b1,b2}(1P) to be consistent with the shape of the ϒ(10753) state. These data indicate that the internal structures of the ϒ(10753) and ϒ(10860) states may differ. Including data at sqrt[s]=10.653 GeV, we also search for the bottomonium equivalent of the X(3872) state decaying into ωϒ(1S). No significant signal is observed for masses between 10.45 and 10.65 GeV/c^{2}.
Language	English
Publishing date	2023-02-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.130.091902
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Article ; Online: Search for a dark photon in e(+)e(-) collisions at BABAR.

Lees, J P / Poireau, V / Tisserand, V / Grauges, E / Palano, A / Eigen, G / Stugu, B / Brown, D N / Feng, M / Kerth, L T / Kolomensky, Yu G / Lee, M J / Lynch, G / Koch, H / Schroeder, T / Hearty, C / Mattison, T S / McKenna, J A / So, R Y /

Khan, A / Blinov, V E / Buzykaev, A R / Druzhinin, V P / Golubev, V B / Kravchenko, E A / Onuchin, A P / Serednyakov, S I / Skovpen, Yu I / Solodov, E P / Todyshev, K Yu / Lankford, A J / Mandelkern, M / Dey, B / Gary, J W / Long, O / Campagnari, C / Franco Sevilla, M / Hong, T M / Kovalskyi, D / Richman, J D / West, C A / Eisner, A M / Lockman, W S / Panduro Vazquez, W / Schumm, B A / Seiden, A / Chao, D S / Cheng, C H / Echenard, B / Flood, K T / Hitlin, D G / Miyashita, T S / Ongmongkolkul, P / Porter, F C / Andreassen, R / Huard, Z / Meadows, B T / Pushpawela, B G / Sokoloff, M D / Sun, L / Bloom, P C / Ford, W T / Gaz, A / Smith, J G / Wagner, S R / Ayad, R / Toki, W H / Spaan, B / Bernard, D / Verderi, M / Playfer, S / Bettoni, D / Bozzi, C / Calabrese, R / Cibinetto, G / Fioravanti, E / Garzia, I / Luppi, E / Piemontese, L / Santoro, V / Calcaterra, A / de Sangro, R / Finocchiaro, G / Martellotti, S / Patteri, P / Peruzzi, I M / Piccolo, M / Rama, M / Zallo, A / Contri, R / Lo Vetere, M / Monge, M R / Passaggio, S / Patrignani, C / Robutti, E / Bhuyan, B / Prasad, V / Adametz, A / Uwer, U / Lacker, H M / Dauncey, P D / Mallik, U / Chen, C / Cochran, J / Prell, S / Ahmed, H / Gritsan, A V / Arnaud, N / Davier, M / Derkach, D / Grosdidier, G / Le Diberder, F / Lutz, A M / Malaescu, B / Roudeau, P / Stocchi, A / Wormser, G / Lange, D J / Wright, D M / Coleman, J P / Fry, J R / Gabathuler, E / Hutchcroft, D E / Payne, D J / Touramanis, C / Bevan, A J / Di Lodovico, F / Sacco, R / Cowan, G / Bougher, J / Davis, C L / Denig, A G / Fritsch, M / Gradl, W / Griessinger, K / Hafner, A / Schubert, K R / Barlow, R J / Lafferty, G D / Cenci, R / Hamilton, B / Jawahery, A / Roberts, D A / Cowan, R / Sciolla, G / Cheaib, R / Patel, P M / Robertson, S H / Neri, N / Palombo, F / Cremaldi, L / Godang, R / Sonnek, P / Summers, D J / Simard, M / Taras, P / De Nardo, G / Onorato, G / Sciacca, C / Martinelli, M / Raven, G / Jessop, C P / LoSecco, J M / Honscheid, K / Kass, R / Feltresi, E / Margoni, M / Morandin, M / Posocco, M / Rotondo, M / Simi, G / Simonetto, F / Stroili, R / Akar, S / Ben-Haim, E / Bomben, M / Bonneaud, G R / Briand, H / Calderini, G / Chauveau, J / Leruste, Ph / Marchiori, G / Ocariz, J / Biasini, M / Manoni, E / Pacetti, S / Rossi, A / Angelini, C / Batignani, G / Bettarini, S / Carpinelli, M / Casarosa, G / Cervelli, A / Chrzaszcz, M / Forti, F / Giorgi, M A / Lusiani, A / Oberhof, B / Paoloni, E / Perez, A / Rizzo, G / Walsh, J J / Lopes Pegna, D / Olsen, J / Smith, A J S / Faccini, R / Ferrarotto, F / Ferroni, F / Gaspero, M / Li Gioi, L / Pilloni, A / Piredda, G / Bünger, C / Dittrich, S / Grünberg, O / Hartmann, T / Hess, M / Leddig, T / Voß, C / Waldi, R / Adye, T / Olaiya, E O / Wilson, F F / Emery, S / Vasseur, G / Anulli, F / Aston, D / Bard, D J / Cartaro, C / Convery, M R / Dorfan, J / Dubois-Felsmann, G P / Dunwoodie, W / Ebert, M / Field, R C / Fulsom, B G / Graham, M T / Hast, C / Innes, W R / Kim, P / Leith, D W G S / Lewis, P / Lindemann, D / Luitz, S / Luth, V / Lynch, H L / MacFarlane, D B / Muller, D R / Neal, H / Perl, M / Pulliam, T / Ratcliff, B N / Roodman, A / Salnikov, A A / Schindler, R H / Snyder, A / Su, D / Sullivan, M K / Va'vra, J / Wisniewski, W J / Wulsin, H W / Purohit, M V / White, R M / Wilson, J R / Randle-Conde, A / Sekula, S J / Bellis, M / Burchat, P R / Puccio, E M T / Alam, M S / Ernst, J A / Gorodeisky, R / Guttman, N / Peimer, D R / Soffer, A / Spanier, S M / Ritchie, J L / Ruland, A M / Schwitters, R F / Wray, B C / Izen, J M / Lou, X C / Bianchi, F / De Mori, F / Filippi, A / Gamba, D / Lanceri, L / Vitale, L / Martinez-Vidal, F / Oyanguren, A / Villanueva-Perez, P / Albert, J / Banerjee, Sw / Beaulieu, A / Bernlochner, F U / Choi, H H F / King, G J / Kowalewski, R / Lewczuk, M J / Lueck, T / Nugent, I M / Roney, J M / Sobie, R J / Tasneem, N / Gershon, T J / Harrison, P F / Latham, T E / Band, H R / Dasu, S / Pan, Y / Prepost, R / Wu, S L

Physical review letters

2014 Volume 113, Issue 20, Page(s) 201801

Abstract: ... e^{-}→γA^{'}, A^{'}→e^{+}e^{-}, μ^{+}μ^{-} using 514 fb^{-1} of data collected with the BABAR ... connecting the dark sector to the standard model. We present a search for a dark photon in the reaction e^ ... in the context of dark matter models. These models introduce a light new mediator, the so-called dark photon (A^ ...

Abstract	Dark sectors charged under a new Abelian interaction have recently received much attention in the context of dark matter models. These models introduce a light new mediator, the so-called dark photon (A^{'}), connecting the dark sector to the standard model. We present a search for a dark photon in the reaction e^{+}e^{-}→γA^{'}, A^{'}→e^{+}e^{-}, μ^{+}μ^{-} using 514 fb^{-1} of data collected with the BABAR detector. We observe no statistically significant deviations from the standard model predictions, and we set 90% confidence level upper limits on the mixing strength between the photon and dark photon at the level of 10^{-4}-10^{-3} for dark photon masses in the range 0.02-10.2 GeV. We further constrain the range of the parameter space favored by interpretations of the discrepancy between the calculated and measured anomalous magnetic moment of the muon.
Language	English
Publishing date	2014-11-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.113.201801
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Engineering tumor-colonizing E. coli Nissle 1917 for detection and treatment of colorectal neoplasia.

Gurbatri, Candice R / Radford, Georgette A / Vrbanac, Laura / Im, Jongwon / Thomas, Elaine M / Coker, Courtney / Taylor, Samuel R / Jang, YoungUk / Sivan, Ayelet / Rhee, Kyu / Saleh, Anas A / Chien, Tiffany / Zandkarimi, Fereshteh / Lia, Ioana / Lannagan, Tamsin R M / Wang, Tongtong / Wright, Josephine A / Kobayashi, Hiroki / Ng, Jia Q /

Lawrence, Matt / Sammour, Tarik / Thomas, Michelle / Lewis, Mark / Papanicolas, Lito / Perry, Joanne / Fitzsimmons, Tracy / Kaazan, Patricia / Lim, Amanda / Stavropoulos, Alexandra M / Gouskos, Dion A / Marker, Julie / Ostroff, Cheri / Rogers, Geraint / Arpaia, Nicholas / Worthley, Daniel L / Woods, Susan L / Danino, Tal

Nature communications

2024 Volume 15, Issue 1, Page(s) 646

Abstract: ... oral delivery of probiotic E. coli Nissle 1917 (EcN) to a genetically-engineered murine model of CRC ...

Abstract	Bioengineered probiotics enable new opportunities to improve colorectal cancer (CRC) screening, prevention and treatment. Here, first, we demonstrate selective colonization of colorectal adenomas after oral delivery of probiotic E. coli Nissle 1917 (EcN) to a genetically-engineered murine model of CRC predisposition and orthotopic models of CRC. We next undertake an interventional, double-blind, dual-centre, prospective clinical trial, in which CRC patients take either placebo or EcN for two weeks prior to resection of neoplastic and adjacent normal colorectal tissue (ACTRN12619000210178). We detect enrichment of EcN in tumor samples over normal tissue from probiotic-treated patients (primary outcome of the trial). Next, we develop early CRC intervention strategies. To detect lesions, we engineer EcN to produce a small molecule, salicylate. Oral delivery of this strain results in increased levels of salicylate in the urine of adenoma-bearing mice, in comparison to healthy controls. To assess therapeutic potential, we engineer EcN to locally release a cytokine, GM-CSF, and blocking nanobodies against PD-L1 and CTLA-4 at the neoplastic site, and demonstrate that oral delivery of this strain reduces adenoma burden by ~50%. Together, these results support the use of EcN as an orally-deliverable platform to detect disease and treat CRC through the production of screening and therapeutic molecules.
MeSH term(s)	Animals ; Humans ; Mice ; Adenoma/diagnosis ; Adenoma/therapy ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/therapy ; Escherichia coli/genetics ; Prospective Studies ; Salicylates ; Double-Blind Method
Chemical Substances	Salicylates
Language	English
Publishing date	2024-01-20
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Multicenter Study
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-44776-4
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Article ; Online: Development and validation of behavioral intention measures of an E-vapor product: intention to try, use, dual use, and switch.

McCaffrey, Stacey A / Zdinak, Jessica Parker / Plunkett, Stephanie / Becker, Elizabeth / Lewis, Jennifer N / Black, Ryan A

Health and quality of life outcomes

2021 Volume 19, Issue 1, Page(s) 123

Abstract: ... planning to quit cigarettes in the next 30 days, (3) e-vapor users, (4) former tobacco users, and (5) never ...

Abstract	Background: The harm caused by tobacco use is primarily attributable to cigarette smoking. Switching completely to non-combustible products may reduce disease risks in adult cigarette smokers who are unable or unwilling to quit. Before a new tobacco product can enter the market or can be marketed as a modified risk tobacco product, the manufacturer must determine the impact that the product will have on the likelihood of changes in tobacco use behavior among both tobacco users and nonusers. One way to estimate change in tobacco use behavior is to assess tobacco users' and nonusers' behavioral intentions toward the product and its marketing, including intentions to try, use, dual use, and switch to the product from cigarettes. The purpose of this study was to develop and validate behavioral intention metrics appropriate for use with current, former, and never adult tobacco users. Methods: Preliminary items were subjected to cognitive testing with adult (1) smokers planning to quit cigarettes in the next 30 days, (2) smokers not planning to quit cigarettes in the next 30 days, (3) e-vapor users, (4) former tobacco users, and (5) never tobacco users. Items were iteratively revised based on feedback during cognitive testing, and surviving items were administered to a large sample of adults (N = 2943) representing the aforementioned sub-groups. Rating scale functioning, reliability, validity, bias, and ability to detect change were evaluated. Results: Examination of the response category thresholds generated by the Rasch model provided evidence that the rating scales were functioning appropriately. Results revealed good stability and excellent internal consistency and person reliability and provided evidence of unidimensionality and convergent validity. Estimates of reliability and validity were similar across sub-groups. A cross-validation sample generally confirmed findings from the validation sample. No items were discarded due to differential item function. Exploratory analyses provided support for ability to detect change. Conclusions: Results from this rigorous, empirical evaluation using large validation and cross-validation samples provide strong support for the psychometric properties of the Intention to Try, Use, Dual Use, and Switch scales with current, former, and never adult tobacco users.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Intention ; Male ; Middle Aged ; Psychometrics/standards ; Reproducibility of Results ; Risk Reduction Behavior ; Smokers/psychology ; Smoking/psychology ; Vaping/psychology ; Young Adult
Language	English
Publishing date	2021-04-15
Publishing country	England
Document type	Journal Article
ISSN	1477-7525
ISSN (online)	1477-7525
DOI	10.1186/s12955-021-01764-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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