Article ; Online: My 60-Year Love Affair with Natural Products.
2021 Volume 84, Issue 3, Page(s) 932–948
Abstract: The author describes his 60-year career in studying the chemistry of natural products, which includes structural, synthetic, and biosynthetic studies of natural products ranging from insect pigments, antibiotics, and fecal mutagens to taxol and other ... ...
Abstract | The author describes his 60-year career in studying the chemistry of natural products, which includes structural, synthetic, and biosynthetic studies of natural products ranging from insect pigments, antibiotics, and fecal mutagens to taxol and other anticancer natural products as well as antimalarial natural products. One of the compounds discussed, napabucasin, is now an anticancer drug in phase III clinical trials. |
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MeSH term(s) | Anti-Bacterial Agents/chemistry ; Antimalarials/chemistry ; Antineoplastic Agents/chemistry ; Biological Products/chemistry ; Career Choice ; Drug Discovery ; Paclitaxel/chemistry |
Chemical Substances | Anti-Bacterial Agents ; Antimalarials ; Antineoplastic Agents ; Biological Products ; Paclitaxel (P88XT4IS4D) |
Language | English |
Publishing date | 2021-01-12 |
Publishing country | United States |
Document type | Journal Article ; Personal Narrative ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. |
ZDB-ID | 304325-3 |
ISSN | 1520-6025 ; 0163-3864 |
ISSN (online) | 1520-6025 |
ISSN | 0163-3864 |
DOI | 10.1021/acs.jnatprod.0c01237 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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