LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 462

Search options

  1. Article ; Online: "Endemic paraplegia of Koza in Kii" in Honcho Koji Innen Shu published in 1689 is probably the earliest description of amyotrophic lateral sclerosis of Kii Peninsula: Presentation of the original and investigation of factuality.

    Kuzuhara, Shigeki

    Rinsho shinkeigaku = Clinical neurology

    2021  Volume 61, Issue 12, Page(s) 815–824

    Abstract: High prevalence of amyotrophic lateral sclerosis (ALS) in Kii Province (Kii) located in southern Kii Peninsula was first pointed out by Kinnosuke Miura in 1911, and epidemiological studies by Kiyoshi Kimura et al. verified extremely high incidence after ... ...

    Abstract High prevalence of amyotrophic lateral sclerosis (ALS) in Kii Province (Kii) located in southern Kii Peninsula was first pointed out by Kinnosuke Miura in 1911, and epidemiological studies by Kiyoshi Kimura et al. verified extremely high incidence after World War II. In 1970s, Yoshiro Yase pointed out that "endemic paraplegia of Koza in Kii" in Honcho Koji Innen Shu published in 1689 would mean the same disorder as that of ALS and be the earliest description of Kii ALS although he gave no clear grounds. In this study, the original of the article was presented with an English translation, and factuality of it was investigated from the viewpoints of geography, geology, culture and history of Kii. As a result, it was shown that the article was probably written based on historical events and that the "endemic paraplegia" meant the same disorder as Kii ALS. The author has concluded that "endemic paraplegia of Koza in Kii" is likely to be the earliest description of Kii ALS since ALS is included in the causes of paraplegias of these kinds.
    MeSH term(s) Amyotrophic Lateral Sclerosis/epidemiology ; Humans ; Incidence ; Japan/epidemiology ; Male ; Paraplegia/epidemiology ; Paraplegia/etiology ; Prevalence
    Language English
    Publishing date 2021-11-06
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.cn-001688
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1455: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 223: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Synthesis and Metalation of Doubly o-Phenylene-Bridged Cyclic Bis(dipyrrin)s with Highly Bent Skeleton of Dibenzoporphyrin(2.1.2.1).

    Kuzuhara, Daiki / Furukawa, Wataru / Kitashiro, Aya / Aratani, Naoki / Yamada, Hiroko

    Chemistry (Weinheim an der Bergstrasse, Germany)

    2016  Volume 22, Issue 30, Page(s) 10671–10678

    Abstract: Facile synthesis of dibenzoporphyrins(2.1.2.1) has been successfully reported by the simple condensation reaction of o-dipyrrolylbenzene with various aldehydes in the presence of a Lewis acid. This reaction enables the preparation of various ... ...

    Abstract Facile synthesis of dibenzoporphyrins(2.1.2.1) has been successfully reported by the simple condensation reaction of o-dipyrrolylbenzene with various aldehydes in the presence of a Lewis acid. This reaction enables the preparation of various dibenzoporphyrin(2.1.2.1) derivatives with p-substituted phenyl groups, five-membered heterocycles, and ethynyl groups at the meso-positions. Dibenzoporphyrins(2.1.2.1) consist of two dipyrrin units that are connected by o-phenylene bridges, which adopt highly bent saddle-shaped structures; this was confirmed by X-ray diffraction analysis. We found that dibenzoporphyrin(2.1.2.1) can be described as a 20π antiaromatic conjugated system, but practically, it is not an antiaromatic macrocycle, which we revealed by (1) H NMR spectroscopy. The redox potentials had good correlations with Hammett substituent constant (σp ) of the substituents at the meso-positions. The free-base dibenzoporphyrin(2.1.2.1) was able to form the metal complexes with nickel(II), copper(II), palladium(II), platinum(II), and tin(IV) ions. These results suggested that dibenzoporphyrin(2.1.2.1) derivatives can be utilized as novel macrocyclic dianionic tetradentate ligands for various metal ions to give complexes with varying optical and electrochemical properties.
    Language English
    Publishing date 2016-07-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1478547-x
    ISSN 1521-3765 ; 0947-6539
    ISSN (online) 1521-3765
    ISSN 0947-6539
    DOI 10.1002/chem.201601083
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: [Lessons from the 116 years (1902-2018) of history of the Japanese Society of Neurology in establishing its identity].

    Kuzuhara, Shigeki

    Rinsho shinkeigaku = Clinical neurology

    2019  Volume 60, Issue 1, Page(s) 1–19

    Abstract: The Japanese Society of Neurology and Psychiatry was founded in 1902 as a joint society of Neurology and Psychiatry, but was renamed the Japanese Society of Psychiatry and Neurology in 1935 because of the stagnation of activities of Neurology and the ... ...

    Abstract The Japanese Society of Neurology and Psychiatry was founded in 1902 as a joint society of Neurology and Psychiatry, but was renamed the Japanese Society of Psychiatry and Neurology in 1935 because of the stagnation of activities of Neurology and the rise of those of Psychiatry. After World War II, activities of Neurology were restored and the Japanese Society of Neurology (JSN) independent from the Societies of Internal Medicine and Psychiatry was established in 1960 after overcoming many difficulties. In 1975, neurology was approved by law as one of the specialized fields of medicine. After that, neurology and JSN developed dramatically, both in research and medical practices. As of 2018, JSN had 9,000 members and more than 5,500 board-certified neurology specialists. JSN successfully hosted the World Congress of Neurology twice in 1981 and 2017. In 2002, JSN accepted the offer to join the Japanese Board of Medical Specialties as one of the subspecialties of Internal Medicine. In 2018 JSN enacted a new policy to upgrade the neurology specialist from a subspecialty of Internal Medicine to an independent major medical field. Lessons of the 116 years of history of the Society would teach us a sensible way to achieve the goals.
    MeSH term(s) History, 20th Century ; History, 21st Century ; Humans ; Japan ; Neurology/history ; Neurology/trends ; Societies, Medical/history ; Societies, Medical/trends
    Language Japanese
    Publishing date 2019-12-17
    Publishing country Japan
    Document type Historical Article ; Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.cn-001353
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1455: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 223: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Training in Mental Singing while Walking Improves Gait Disturbance in Parkinson’s Disease Patients

    Satoh, Masayuki / Kuzuhara, Shigeki

    European Neurology

    2008  Volume 60, Issue 5, Page(s) 237–243

    Abstract: Patients with Parkinson’s disease (PD) have various types of gait disturbance that are thought ...

    Institution Mie St. Cross Hospital and Department of Neurology, Mie University School of Medicine, Tsu, Japan
    Abstract Patients with Parkinson’s disease (PD) have various types of gait disturbance that are thought to result from impairments in motor timing. Gait disturbances are markedly improved with the use of appropriate visual and auditory cues. In this study, patients suffering from mild to moderate PD underwent a structured music therapy session in which they were trained to walk while mentally singing. The patients were trained in 7 progressive tasks, with a final goal of walking while mentally singing. Before and after the training session, they were videotaped. The video was analyzed for time and steps while walking straight paths and while turning. After a single session of training, the time and steps were significantly improved in both situations. Follow-up interviews with the patients indicated that they effectively utilized mental singing while walking in their daily lives. We propose that singing regulates basal ganglia function and allows patients with PD to keep time regularly. The task used in the present study was simple, required no special tools, and could be utilized anytime and anyplace. Thus, walking while mentally singing has potential for improving the gait of individuals with PD.
    Keywords Parkinson’s disease ; Gait disturbance ; Singing ; Music therapy
    Language English
    Publishing date 2008-08-29
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 209426-5
    ISSN 1421-9913 ; 0014-3022
    ISSN (online) 1421-9913
    ISSN 0014-3022
    DOI 10.1159/000151699
    Database Karger publisher's database

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 575: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Internal structural changes in keratin fibres resulting from combined hair waving and stress relaxation treatments: a Raman spectroscopic investigation.

    Kuzuhara, A

    International journal of cosmetic science

    2016  Volume 38, Issue 2, Page(s) 201–209

    Abstract: ... In particular, the three disulphide (-SS-) conformations in human hair were compared by S-S band analysis ... process after reduction accelerated the reconnection of -SS- (GGG and GGT) groups. Moreover, the S-O band ...

    Abstract Objective: The objective of our research was to investigate the influence of chemical treatments (reduction, stress relaxation and oxidation) on hair keratin fibres.
    Methods: The structure of cross-sections at various depths of virgin white human hair resulting from permanent waving treatments with stress relaxation process was directly analysed at a molecular level using Raman spectroscopy. In particular, the three disulphide (-SS-) conformations in human hair were compared by S-S band analysis.
    Results: The gauche-gauche-gauche (GGG) and gauche-gauche-trans (GGT) contents of -SS- groups remarkably decreased, while the trans-gauche-trans (TGT) content was not changed by performing the reduction process with thioglycolic acid. In addition, the high-temperature stress relaxation process after reduction accelerated the disconnection of -SS- (GGG and GGT) groups in the human hair, while the low-temperature stress relaxation process after reduction accelerated the reconnection of -SS- (GGG and GGT) groups. Moreover, the S-O band intensity at 1042 cm(-1) , assigned to cysteic acid, existing in the cuticle region and the surface of the cortex region increased, while the GGG content significantly decreased by performing the oxidation process after the reduction and the high-temperature stress relaxation processes.
    Conclusion: The author concluded that the high-temperature relaxation process after reduction accelerated the disconnection of -SS- (GGG and GGT) groups, thereby leading to the remarkable local molecular disorganization (an increase in the cysteic acid content and a decrease in the GGG content) on the cuticle and cortex cells during the oxidation process.
    MeSH term(s) Hair ; Humans ; Keratins/chemistry ; Molecular Structure ; Spectrum Analysis, Raman/methods
    Chemical Substances Keratins (68238-35-7)
    Language English
    Publishing date 2016-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 198917-0
    ISSN 1468-2494 ; 0142-5463
    ISSN (online) 1468-2494
    ISSN 0142-5463
    DOI 10.1111/ics.12278
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2391: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: Association between Social Jetlag and Objective Physical Activity among Female University Students of Japan: A Cross-sectional Study

    Shibata, Masashi / Fujibayashi, Mami / Shibata, Shiori / Kuzuhara, Kenji / Tanida, Keiko

    Sleep Science

    2024  

    Abstract: Objective: Discrepancies between sleep timing on work/school and free days, also known as social jetlag (SJL), can cause health problems. These issues occur most often in individuals from adolescence to the early 20s, which is equivalent to the age of ... ...

    Abstract Objective: Discrepancies between sleep timing on work/school and free days, also known as social jetlag (SJL), can cause health problems. These issues occur most often in individuals from adolescence to the early 20s, which is equivalent to the age of university students. This study was designed to explore the recommended level of physical activity required to minimize SJL and to examine the relationship between SJL and objective physical activity among female university students.
    Methods: We assessed the SJL of 68 female students using the Japanese version of the Munich Chronotype Questionnaire. The objective physical activity and sleep variables of subjects were also evaluated at 3 to 4 weeks using a small triaxial accelerometer.
    Results: A significant negative correlation was found between SJL and physical activity on both free (r = − 0.435, p  < 0.001) and school days (r = − 0.341, p  < 0.01). According to the linear regression analysis, physical activity of 11,174 steps on school days and 10,713 steps on free days had the lowest SJL value. Total sleep time on free days had a significant positive correlation with SJL (r = 0.399, p  < 0.001) and a negative correlation with physical activity (r = − 0.520, p  < 0.001).
    Discussion: Our results suggest that substantial SJL may cause chronic fatigue and lead to a low level of physical activity in female university students. These results also imply that the recommended level of physical activity necessary to minimize SJL among these students is around 11,000 steps on both school and free days.
    Keywords social jetlag ; physical activity ; circadian rhythm ; university students
    Language English
    Publishing date 2024-02-20
    Publisher Thieme Revinter Publicações Ltda.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2697016-8
    ISSN 1984-0063 ; 1984-0659 ; 1984-0063
    ISSN (online) 1984-0063
    ISSN 1984-0659 ; 1984-0063
    DOI 10.1055/s-0043-1777777
    Database Thieme publisher's database

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: [Robert Wartenberg: the neurologist, the teacher, and the man].

    Kuzuhara, Shigeki

    Brain and nerve = Shinkei kenkyu no shinpo

    2014  Volume 66, Issue 11, Page(s) 1301–1308

    Abstract: Wartenberg was born in 1887 in Grodno, old Lithuania (present-day Belarus). He received his medical degree from the University of Rostock in 1919, and worked at the University of Freiburg until 1935, when he immigrated to the United States to escape Nazi ...

    Abstract Wartenberg was born in 1887 in Grodno, old Lithuania (present-day Belarus). He received his medical degree from the University of Rostock in 1919, and worked at the University of Freiburg until 1935, when he immigrated to the United States to escape Nazi Germany. He then worked at the University of California, San Francisco, and was appointed Clinical Professor of Neurology in 1952. He died of a heart illness in 1956. Wartenberg wrote more than 150 papers on clinical neurology in German and English, especially on reflexes and signs. His books, "Examination of Reflex" and "Diagnostic Tests in Neurology" were translated into many languages, including Japanese. His contribution to the study of reflexes includes Wartenberg's reflex of the thumb, head dropping test in Parkinson's disease, necessity of differentiating abdominal muscle and abdominal skin muscle reflexes, and many others. He had knowledge, skill, art and ability enough to translate difficult problems into tangible methods of diagnosis and treatment. He tried to diagnose and treat patients quickly, with minimum laboratory tests, and avoided invasive tests and expense of time and money. His efforts to provide patients with the best treatment in terms of time, safety, and cost, is the essence of medicine and is still worth practicing in modern neurology using advanced technology.
    MeSH term(s) Education, Medical ; History, 19th Century ; History, 20th Century ; Humans ; Neurologic Examination/history ; Neurology/education ; Neurology/history ; Reflex/physiology ; United States
    Language Japanese
    Publishing date 2014-11
    Publishing country Japan
    Document type Biography ; English Abstract ; Historical Article ; Journal Article ; Portraits
    ZDB-ID 390389-8
    ISSN 1344-8129 ; 1881-6096 ; 0006-8969
    ISSN (online) 1344-8129
    ISSN 1881-6096 ; 0006-8969
    DOI 10.11477/mf.1416200032
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 398: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Recovery of Platinum Group Metals from Spent Automotive Catalysts Using Lithium Salts and Hydrochloric Acid.

    Kuzuhara, Shunsuke / Ota, Mina / Kasuya, Ryo

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 22

    Abstract: The recovery of platinum group metals (PGMs) from waste materials involves dissolving the waste in an aqueous solution. However, since PGMs are precious metals, their dissolution requires strong oxidizing agents such as chlorine gas and aqua regia. In ... ...

    Abstract The recovery of platinum group metals (PGMs) from waste materials involves dissolving the waste in an aqueous solution. However, since PGMs are precious metals, their dissolution requires strong oxidizing agents such as chlorine gas and aqua regia. In this study, we aimed to recover PGMs via the calcination of spent automotive catalysts (autocatalysts) with Li salts based on the concept of "spent autocatalyst + waste lithium-ion batteries" and leaching with only HCl. The results suggest that, when Li
    Language English
    Publishing date 2021-11-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14226843
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: [Comments on the issue and future strategy of policy toward the rare intractable diseases from a standpoint of a neurology specialist].

    Kuzuhara, Shigeki

    Rinsho shinkeigaku = Clinical neurology

    2013  Volume 23, Issue 11, Page(s) 1290

    MeSH term(s) Chronic Disease/therapy ; Humans ; Japan ; Legislation, Medical ; Neurology ; Rare Diseases/therapy
    Language Japanese
    Publishing date 2013-09-05
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 604200-4
    ISSN 1882-0654 ; 0009-918X
    ISSN (online) 1882-0654
    ISSN 0009-918X
    DOI 10.5692/clinicalneurol.53.1290
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 1455: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 223: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Fibular morphology is not associated with incidence of peroneal tendon dislocation.

    Goto, Kazumi / Sanada, Takaki / Honda, Eisaburo / Sameshima, Shin / Murakami, Tomoki / Inagawa, Miyu / Ishida, Yutaro / Kuzuhara, Ryota / Iwaso, Hiroshi

    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

    2024  

    Abstract: Purpose: The association of peroneal tendon dislocation with peroneal bone morphology and postoperative redislocation rates remains unknown. This study compared the fibula morphology in patients with peroneal tendon dislocation with that in a control ... ...

    Abstract Purpose: The association of peroneal tendon dislocation with peroneal bone morphology and postoperative redislocation rates remains unknown. This study compared the fibula morphology in patients with peroneal tendon dislocation with that in a control population.
    Methods: The study enrolled 48 patients who underwent surgery for peroneal tendon dislocation at our institution during between 2018 and 2023. Thirty-five patients with preoperative magnetic resonance imaging of the ankle were defined as Group D and 35 with magnetic resonance imaging of the ankle for other reasons and with similar background data were selected as the control group (Group C). The posterior tilting angle of the fibula, posterolateral angle and posterolateral edge angle were evaluated at the plafond level. The posterior tilting angle, posterolateral angle and retromalleolar bone shape according to the Rosenberg classification (flat, convex, concave) were evaluated at the midpoint between the plafond and the tip.
    Results: At the plafond level, the posterior tilting, posterolateral and posterolateral edge angles were 57.7 ± 11.1°, 123.8 ± 12.3° and 90.8 ± 13.7°, respectively, in Group D and 64.1 ± 15.4°, 121.1 ± 12.3° and 88.7 ± 12.2°, respectively, in Group C, with no significant differences. No significant between-group differences existed in the posterior tilting and posterolateral angles at the midpoint level. Moreover, no significant differences existed in distribution of the bone geometry according to the Rosenberg classification.
    Conclusion: There were no differences in morphology between patients with peroneal tendon dislocation and controls. This study provides useful information on the indications for primary surgery and whether bony approach is useful for peroneal tendon dislocation.
    Level of evidence: Level IV.
    Language English
    Publishing date 2024-03-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1159064-6
    ISSN 1433-7347 ; 0942-2056
    ISSN (online) 1433-7347
    ISSN 0942-2056
    DOI 10.1002/ksa.12160
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3742: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top