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  1. AU=Lautz Jaclyn
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  1. Article ; Online: Turbulent water coupling in shock wave lithotripsy.

    Lautz, Jaclyn / Sankin, Georgy / Zhong, Pei

    Physics in medicine and biology

    2013  Volume 58, Issue 3, Page(s) 735–748

    Abstract: Previous studies have demonstrated that stone comminution decreases with increased pulse repetition frequency as a result of bubble proliferation in the cavitation field of a shock wave lithotripter (Pishchalnikov et al 2011 J. Acoust. Soc. Am. 130 EL87- ... ...

    Abstract Previous studies have demonstrated that stone comminution decreases with increased pulse repetition frequency as a result of bubble proliferation in the cavitation field of a shock wave lithotripter (Pishchalnikov et al 2011 J. Acoust. Soc. Am. 130 EL87-93). If cavitation nuclei remain in the propagation path of successive lithotripter pulses, especially in the acoustic coupling cushion of the shock wave source, they will consume part of the incident wave energy, leading to reduced tensile pressure in the focal region and thus lower stone comminution efficiency. We introduce a method to remove cavitation nuclei from the coupling cushion between successive shock exposures using a jet of degassed water. As a result, pre-focal bubble nuclei lifetime quantified by B-mode ultrasound imaging was reduced from 7 to 0.3 s by a jet with an exit velocity of 62 cm s(-1). Stone fragmentation (percent mass <2 mm) after 250 shocks delivered at 1 Hz was enhanced from 22 ± 6% to 33 ± 5% (p = 0.007) in water without interposing tissue mimicking materials. Stone fragmentation after 500 shocks delivered at 2 Hz was increased from 18 ± 6% to 28 ± 8% (p = 0.04) with an interposing tissue phantom of 8 cm thick. These results demonstrate the critical influence of cavitation bubbles in the coupling cushion on stone comminution and suggest a potential strategy to improve the efficacy of contemporary shock wave lithotripters.
    MeSH term(s) Acoustics ; Electromagnetic Phenomena ; Humans ; Hydrodynamics ; Lithotripsy/instrumentation ; Lithotripsy/methods ; Phantoms, Imaging ; Water
    Chemical Substances Water (059QF0KO0R)
    Language English
    Publishing date 2013-01-15
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/0031-9155/58/3/735
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 199: Show issues Location:
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  2. Article: Displacement of particles in microfluidics by laser-generated tandem bubbles.

    Lautz, Jaclyn / Sankin, Georgy / Yuan, Fang / Zhong, Pei

    Applied physics letters

    2010  Volume 97, Issue 18, Page(s) 183701

    Abstract: The dynamic interaction between laser-generated tandem bubble and individual polystyrene particles of 2 and 10 μm in diameter is studied in a microfluidic channel (25 μm height) by high-speed imaging and particle image velocimetry. The asymmetric ... ...

    Abstract The dynamic interaction between laser-generated tandem bubble and individual polystyrene particles of 2 and 10 μm in diameter is studied in a microfluidic channel (25 μm height) by high-speed imaging and particle image velocimetry. The asymmetric collapse of the tandem bubble produces a pair of microjets and associated long-lasting vortices that can propel a single particle to a maximum velocity of 1.4 m∕s in 30 μs after the bubble collapse with a resultant directional displacement up to 60 μm in 150 μs. This method may be useful for high-throughput cell sorting in microfluidic devices.
    Language English
    Publishing date 2010-11-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1469436-0
    ISSN 1077-3118 ; 0003-6951
    ISSN (online) 1077-3118
    ISSN 0003-6951
    DOI 10.1063/1.3511538
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Evaluation of Novel Ball-Tip Holmium Laser Fiber: Impact on Ureteroscope Performance and Fragmentation Efficiency.

    Shin, Richard H / Lautz, Jaclyn M / Cabrera, Fernando J / Shami, Constandi John / Goldsmith, Zachariah G / Kuntz, Nicholas J / Kaplan, Adam G / Neisius, Andreas / Simmons, Walter Neal / Preminger, Glenn M / Lipkin, Michael E

    Journal of endourology

    2016  Volume 30, Issue 2, Page(s) 189–194

    Abstract: Purpose: A novel ball tip (BT) holmium laser fiber has recently been developed, which features a modified rounded tip. The modification is purported to aid in insertion and minimize damage to the ureteroscope working channel. We evaluated this laser ... ...

    Abstract Purpose: A novel ball tip (BT) holmium laser fiber has recently been developed, which features a modified rounded tip. The modification is purported to aid in insertion and minimize damage to the ureteroscope working channel. We evaluated this laser fiber with regard to stone comminution, tip degradation, insertional force into the ureteroscope, and impact on ureteroscope deflection.
    Materials and methods: A 242 μm BT fiber and a standard flat tip (SF) fiber were compared. Four kilojoules was delivered to a BegoStone over a constant surface area using settings of 0.2/50, 0.6/6, 0.8/8, and 1 J/10 Hz. Fiber tip degradation was measured at 1 and 4 kJ. Ureteroscope deflection was measured with the Olympus URF-P5, URF-P6, and URF-V. Insertion force into a 270° angled ureteroscope sheath model was measured.
    Results: A sample size of five fibers was used for each comminution energy setting. Comminution increased with pulse energy without significant difference between fibers. No significant differences in tip degradation were observed. Both fibers reduced deflection (10°-30°) in all ureteroscopes without significant differences between fibers. Four new fibers paired with new sheath models were used to test insertion force. The BT insertion forces were approximately one-third of the SF. One SF fiber caused significant damage to the sheath and could not be advanced completely.
    Conclusions: The BT fiber has comparable comminution, tip degradation, and ureteroscope deflection performance compared with the SF fiber while exhibiting reduced insertion force within an aggressively deflected working sheath. The new tip design is likely protective of the working channel without loss of performance.
    MeSH term(s) Humans ; Kidney Calculi/therapy ; Lasers, Solid-State/therapeutic use ; Lithotripsy, Laser/instrumentation ; Models, Anatomic ; Ureteral Calculi/therapy ; Ureteroscopy/instrumentation
    Language English
    Publishing date 2016-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 356931-7
    ISSN 1557-900X ; 0892-7790
    ISSN (online) 1557-900X
    ISSN 0892-7790
    DOI 10.1089/end.2015.0300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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