LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 7 of total 7

Search options

  1. Article ; Online: Two cases of coronavirus 2019-related cardiomyopathy in pregnancy.

    Juusela, Alexander / Nazir, Munir / Gimovsky, Martin

    American journal of obstetrics & gynecology MFM

    2020  Volume 2, Issue 2, Page(s) 100113

    Abstract: At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%-64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%-45% and ... ...

    Abstract At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%-64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%-45% and hypokinesis. Viral myocarditis and cardiomyopathy have also been reported in nonpregnant coronavirus disease 2019 patients. A case series of nonpregnant patients with coronavirus disease 2019 found that 33% of those in intensive care developed cardiomyopathy. More data are needed to ascertain the incidence of cardiomyopathy from coronavirus disease 2019 in pregnancy, in all pregnant women with coronavirus disease 2019, and those with severe disease (eg, pneumonia). We suggest an echocardiogram in pregnant women with coronavirus disease 2019 pneumonia, in particular those necessitating oxygen, or those who are critically ill, and we recommend the use of handheld, point-of-care devices where possible to minimize contamination of staff and traditional large echocardiogram machines.
    MeSH term(s) Adult ; Anti-Arrhythmia Agents/therapeutic use ; Antibodies, Monoclonal, Humanized/therapeutic use ; Anticonvulsants/therapeutic use ; Blood Gas Analysis ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/physiopathology ; COVID-19/therapy ; COVID-19 Nucleic Acid Testing ; Cardiomyopathies/diagnosis ; Cardiomyopathies/etiology ; Cardiomyopathies/physiopathology ; Cardiomyopathies/therapy ; Cesarean Section ; Diabetes, Gestational ; Diuretics/therapeutic use ; Echocardiography ; Enzyme Inhibitors/therapeutic use ; Female ; Fever ; Furosemide/therapeutic use ; Heart Arrest/etiology ; Heart Arrest/therapy ; Heart Failure/diagnosis ; Heart Failure/etiology ; Heart Failure/physiopathology ; Heart Failure/therapy ; Humans ; Hydroxychloroquine/therapeutic use ; Hypoxia/etiology ; Hypoxia/therapy ; Intubation, Intratracheal ; Magnesium Sulfate/therapeutic use ; Metoprolol/therapeutic use ; Middle Aged ; Obesity, Maternal/complications ; Oxygen Inhalation Therapy ; Point-of-Care Systems ; Pre-Eclampsia/drug therapy ; Pre-Eclampsia/physiopathology ; Pregnancy ; Pregnancy Complications, Cardiovascular/diagnosis ; Pregnancy Complications, Cardiovascular/physiopathology ; Pregnancy Complications, Cardiovascular/therapy ; Pregnancy Complications, Infectious/diagnosis ; Pregnancy Complications, Infectious/physiopathology ; Pregnancy Complications, Infectious/therapy ; Respiration, Artificial ; Return of Spontaneous Circulation ; SARS-CoV-2 ; Severity of Illness Index ; Stroke Volume ; Tachycardia/drug therapy ; Tachycardia/physiopathology ; Tachycardia, Supraventricular/drug therapy ; Tachycardia, Supraventricular/etiology
    Chemical Substances Anti-Arrhythmia Agents ; Antibodies, Monoclonal, Humanized ; Anticonvulsants ; Diuretics ; Enzyme Inhibitors ; Hydroxychloroquine (4QWG6N8QKH) ; Magnesium Sulfate (7487-88-9) ; Furosemide (7LXU5N7ZO5) ; Metoprolol (GEB06NHM23) ; tocilizumab (I031V2H011)
    Keywords covid19
    Language English
    Publishing date 2020-04-03
    Publishing country United States
    Document type Case Reports ; Journal Article
    ISSN 2589-9333
    ISSN (online) 2589-9333
    DOI 10.1016/j.ajogmf.2020.100113
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Robotic-Assisted Laparoscopic Cervicovaginal Myomectomy.

    Javadian, Pouya / Juusela, Alexander / Nezhat, Farr

    Journal of minimally invasive gynecology

    2018  Volume 26, Issue 1, Page(s) 31

    Abstract: Study objective: To illustrate a robotic-assisted laparoscopic resection for cervicovaginal myomectomy.: Design: Step-wise instruction using video and case report (Canadian Task Force classification III).: Setting: A tertiary referral center.: ... ...

    Abstract Study objective: To illustrate a robotic-assisted laparoscopic resection for cervicovaginal myomectomy.
    Design: Step-wise instruction using video and case report (Canadian Task Force classification III).
    Setting: A tertiary referral center.
    Patient: A 39-year-old woman.
    Intervention: Robotic-assisted laparoscopy resection of leiomyoma.
    Measurements and main results: A 39-year-old woman, gravida 0, body mass index of 23.0 kg/m
    Conclusion: Robot-assisted laparoscopic surgery is a feasible approach for cervicovaginal myoma with minimal complications.
    MeSH term(s) Adult ; Female ; Humans ; Laparoscopy/methods ; Leiomyoma/surgery ; Myoma/surgery ; Neoplasm Recurrence, Local/surgery ; Organ Sparing Treatments ; Robotic Surgical Procedures ; Robotics ; Treatment Outcome ; Uterine Artery Embolization ; Uterine Myomectomy/methods ; Uterine Neoplasms/surgery
    Language English
    Publishing date 2018-03-28
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2186934-0
    ISSN 1553-4669 ; 1553-4650
    ISSN (online) 1553-4669
    ISSN 1553-4650
    DOI 10.1016/j.jmig.2018.03.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4205: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Two cases of coronavirus 2019-related cardiomyopathy in pregnancy

    Juusela, Alexander / Nazir, Munir / Gimovsky, Martin

    Am J Obstet Gynecol MFM

    Abstract: At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%-64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%-45% and ... ...

    Abstract At our institution, 2 of the initial 7 pregnant patients with confirmed coronavirus disease 2019 severe infection (28.6%; 95% CI, 8.2%-64.1%) developed cardiac dysfunction with moderately reduced left ventricular ejection fractions of 40%-45% and hypokinesis. Viral myocarditis and cardiomyopathy have also been reported in nonpregnant coronavirus disease 2019 patients. A case series of nonpregnant patients with coronavirus disease 2019 found that 33% of those in intensive care developed cardiomyopathy. More data are needed to ascertain the incidence of cardiomyopathy from coronavirus disease 2019 in pregnancy, in all pregnant women with coronavirus disease 2019, and those with severe disease (eg, pneumonia). We suggest an echocardiogram in pregnant women with coronavirus disease 2019 pneumonia, in particular those necessitating oxygen, or those who are critically ill, and we recommend the use of handheld, point-of-care devices where possible to minimize contamination of staff and traditional large echocardiogram machines.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #30778
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Mayer-Rokitansky-Küster-Hauser Syndrome With Bilateral Ovarian Sertoli Cell Tumors: Review of the Literature and Report of a Rare Case.

    Juusela, Alexander L / Naghi, Ilana / Thani, Suresh

    Female pelvic medicine & reconstructive surgery

    2017  Volume 24, Issue 5, Page(s) e32–e34

    Abstract: Background: Patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome are infertile secondary to hypoplasia or complete agenesis of the uterus, yet they remain at risk of primary neoplasms of the ovaries because embryologically the uterus and ovaries ...

    Abstract Background: Patients with Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome are infertile secondary to hypoplasia or complete agenesis of the uterus, yet they remain at risk of primary neoplasms of the ovaries because embryologically the uterus and ovaries develop via separate mechanisms.
    Case: A 72-year-old nulliparous woman with a history of primary amenorrhea underwent an exploratory laparotomy for a suspected uterine fibroid. In addition to the pelvic mass, the patient was found to have findings consistent with MRKH syndrome. Postoperative pathological examination demonstrated bilateral ovarian Sertoli cell tumors.
    Conclusions: The case presented is unique in that 2 rare pathologies, bilateral Sertoli cell tumors of the ovary and MRKH syndrome, developed concomitantly in the same patient.
    MeSH term(s) 46, XX Disorders of Sex Development/complications ; 46, XX Disorders of Sex Development/diagnosis ; Aged ; Congenital Abnormalities/diagnosis ; Female ; Humans ; Mullerian Ducts/abnormalities ; Ovarian Neoplasms/complications ; Ovarian Neoplasms/diagnosis ; Ovarian Neoplasms/pathology ; Ovarian Neoplasms/surgery ; Rare Diseases/complications ; Rare Diseases/diagnosis ; Rare Diseases/pathology ; Rare Diseases/surgery ; Sertoli Cell Tumor/complications ; Sertoli Cell Tumor/diagnosis ; Sertoli Cell Tumor/pathology ; Sertoli Cell Tumor/surgery
    Language English
    Publishing date 2017-09-20
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2542707-6
    ISSN 2154-4212 ; 2151-8378
    ISSN (online) 2154-4212
    ISSN 2151-8378
    DOI 10.1097/SPV.0000000000000483
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4599: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Grade III subcapsular liver hematoma secondary to HELLP syndrome: A case report of conservative management.

    Bradke, Daniel / Tran, Ashley / Ambarus, Tatiana / Nazir, Munir / Markowski, Maryann / Juusela, Alexander

    Case reports in women's health

    2019  Volume 25, Page(s) e00169

    Abstract: Subcapsular liver hematoma (SLH) is a rare condition that is associated with preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. A high level of suspicion, early diagnosis, and coordinated, intensive multidisciplinary ... ...

    Abstract Subcapsular liver hematoma (SLH) is a rare condition that is associated with preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome. A high level of suspicion, early diagnosis, and coordinated, intensive multidisciplinary management are necessary to monitor for serious complications and prevent death. Options include conservative management, hepatic resection, hepatic artery ligation and liver transplantation. This paper describes a 34-year-old woman with HELLP syndrome who developed a large grade III SLH that was managed conservatively.
    Language English
    Publishing date 2019-12-24
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2800286-6
    ISSN 2214-9112 ; 2214-9112
    ISSN (online) 2214-9112
    ISSN 2214-9112
    DOI 10.1016/j.crwh.2019.e00169
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Maternal plasma syndecan-1: a biomarker for fetal growth restriction.

    Juusela, Alexander / Jung, Eunjung / Gallo, Dahiana M / Bosco, Mariachiara / Suksai, Manaphat / Diaz-Primera, Ramiro / Tarca, Adi L / Than, Nandor Gabor / Gotsch, Francesca / Romero, Roberto / Chaiworapongsa, Tinnakorn

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2022  Volume 36, Issue 1, Page(s) 2150074

    Abstract: Objective: The identification of fetal growth disorders is an important clinical priority given that they increase the risk of perinatal morbidity and mortality as well as long-term diseases. A subset of small-for-gestational-age (SGA) infants are ... ...

    Abstract Objective: The identification of fetal growth disorders is an important clinical priority given that they increase the risk of perinatal morbidity and mortality as well as long-term diseases. A subset of small-for-gestational-age (SGA) infants are growth-restricted, and this condition is often attributed to placental insufficiency. Syndecan-1, a product of the degradation of the endothelial glycocalyx, has been proposed as a biomarker of endothelial damage in different pathologies. During pregnancy, a "specialized" form of the glycocalyx-the "syncytiotrophoblast glycocalyx"-covers the placental villi. The purpose of this study was to determine whether the concentration of maternal plasma syndecan-1 can be proposed as a biomarker for fetal growth restriction.
    Study design: A cross-sectional study was designed to include women with normal pregnancy (
    Results: (1) Plasma syndecan-1 concentration followed a nonlinear increase with gestational age in uncomplicated pregnancies (R
    Conclusion: Low maternal plasma syndecan-1 may reflect placental diseases and this protein could be a biomarker for fetal growth restriction. However, as a sole biomarker for this condition, its accuracy is low.
    MeSH term(s) Infant, Newborn ; Infant ; Pregnancy ; Female ; Humans ; Fetal Growth Retardation/diagnosis ; Fetal Growth Retardation/pathology ; Placenta/pathology ; Cross-Sectional Studies ; Syndecan-1 ; Infant, Small for Gestational Age ; Biomarkers ; Umbilical Arteries/diagnostic imaging ; Ultrasonography, Prenatal ; Ultrasonography, Doppler
    Chemical Substances Syndecan-1 ; Biomarkers
    Language English
    Publishing date 2022-12-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2022.2150074
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3510: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Ursodeoxycholic acid in intrahepatic cholestasis of pregnancy: a systematic review and individual participant data meta-analysis.

    Ovadia, Caroline / Sajous, Jenna / Seed, Paul T / Patel, Kajol / Williamson, Nicholas J / Attilakos, George / Azzaroli, Francesco / Bacq, Yannick / Batsry, Linoy / Broom, Kelsey / Brun-Furrer, Romana / Bull, Laura / Chambers, Jenny / Cui, Yue / Ding, Min / Dixon, Peter H / Estiú, Maria C / Gardiner, Fergus W / Geenes, Victoria /
    Grymowicz, Monika / Günaydin, Berrin / Hague, William M / Haslinger, Christian / Hu, Yayi / Indraccolo, Ugo / Juusela, Alexander / Kane, Stefan C / Kebapcilar, Ayse / Kebapcilar, Levent / Kohari, Katherine / Kondrackienė, Jūratė / Koster, Maria P H / Lee, Richard H / Liu, Xiaohua / Locatelli, Anna / Macias, Rocio I R / Madazli, Riza / Majewska, Agata / Maksym, Kasia / Marathe, Jessica A / Morton, Adam / Oudijk, Martijn A / Öztekin, Deniz / Peek, Michael J / Shennan, Andrew H / Tribe, Rachel M / Tripodi, Valeria / Türk Özterlemez, Naciye / Vasavan, Tharni / Wong, L F Audris / Yinon, Yoav / Zhang, Qianwen / Zloto, Keren / Marschall, Hanns-Ulrich / Thornton, Jim / Chappell, Lucy C / Williamson, Catherine

    The lancet. Gastroenterology & hepatology

    2021  Volume 6, Issue 7, Page(s) 547–558

    Abstract: Background: Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth, preterm birth, and neonatal unit admission). We aimed to examine ... ...

    Abstract Background: Ursodeoxycholic acid is commonly used to treat intrahepatic cholestasis of pregnancy, yet its largest trial detected minimal benefit for a composite outcome (stillbirth, preterm birth, and neonatal unit admission). We aimed to examine whether ursodeoxycholic acid affects specific adverse perinatal outcomes.
    Methods: In this systematic review and individual participant data meta-analysis, we searched PubMed, Web of Science, Embase, MEDLINE, CINAHL, Global Health, MIDIRS, and Cochrane without language restrictions for relevant articles published between database inception, and Jan 1, 2020, using search terms referencing intrahepatic cholestasis of pregnancy, ursodeoxycholic acid, and perinatal outcomes. Eligible studies had 30 or more study participants and reported on at least one individual with intrahepatic cholestasis of pregnancy and bile acid concentrations of 40 μmol/L or more. We also included two unpublished cohort studies. Individual participant data were collected from the authors of selected studies. The primary outcome was the prevalence of stillbirth, for which we anticipated there would be insufficient data to achieve statistical power. Therefore, we included a composite of stillbirth and preterm birth as a main secondary outcome. A mixed-effects meta-analysis was done using multi-level modelling and adjusting for bile acid concentration, parity, and multifetal pregnancy. Individual participant data analyses were done for all studies and in different subgroups, which were produced by limiting analyses to randomised controlled trials only, singleton pregnancies only, or two-arm studies only. This study is registered with PROSPERO, CRD42019131495.
    Findings: The authors of the 85 studies fulfilling our inclusion criteria were contacted. Individual participant data from 6974 women in 34 studies were included in the meta-analysis, of whom 4726 (67·8%) took ursodeoxycholic acid. Stillbirth occurred in 35 (0·7%) of 5097 fetuses among women with intrahepatic cholestasis of pregnancy treated with ursodeoxycholic acid and in 12 (0·6%) of 2038 fetuses among women with intrahepatic cholestasis of pregnancy not treated with ursodeoxycholic acid (adjusted odds ratio [aOR] 1·04, 95% CI 0·35-3·07; p=0·95). Ursodeoxycholic acid treatment also had no effect on the prevalence of stillbirth when considering only randomised controlled trials (aOR 0·29, 95% CI 0·04-2·42; p=0·25). Ursodeoxycholic acid treatment had no effect on the prevalence of the composite outcome in all studies (aOR 1·28, 95% CI 0·86-1·91; p=0·22), but was associated with a reduced composite outcome when considering only randomised controlled trials (0·60, 0·39-0·91; p=0·016).
    Interpretation: Ursodeoxycholic acid treatment had no significant effect on the prevalence of stillbirth in women with intrahepatic cholestasis of pregnancy, but our analysis was probably limited by the low overall event rate. However, when considering only randomised controlled trials, ursodeoxycholic acid was associated with a reduction in stillbirth in combination with preterm birth, providing evidence for the clinical benefit of antenatal ursodeoxycholic acid treatment.
    Funding: Tommy's, the Wellcome Trust, ICP Support, and the National Institute for Health Research.
    MeSH term(s) Cholagogues and Choleretics/therapeutic use ; Cholestasis, Intrahepatic/drug therapy ; Female ; Humans ; Pregnancy ; Pregnancy Complications/drug therapy ; Ursodeoxycholic Acid/therapeutic use
    Chemical Substances Cholagogues and Choleretics ; Ursodeoxycholic Acid (724L30Y2QR)
    Language English
    Publishing date 2021-04-27
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ISSN 2468-1253
    ISSN (online) 2468-1253
    DOI 10.1016/S2468-1253(21)00074-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top