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  1. Book ; Online ; E-Book: Mathematical approaches to liver transplantation

    Massad, Eduardo / Filho, Homero Chaib

    2020  

    Author's details Eduardo Massad, Eleazar Chaib
    Language English
    Size 1 Online-Ressource (xvii, 172 Seiten), Illustrationen, Diagramme
    Publisher Elsevier Academic Press
    Publishing place London
    Publishing country Great Britain
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020431975
    ISBN 978-0-12-817437-1 ; 9780128174364 ; 0-12-817437-4 ; 0128174366
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Fuzzy logic in action

    Massad, Eduardo

    applications in epidemiology and beyond

    (Studies in fuzziness and soft computing ; 232)

    2008  

    Author's details Eduardo Massad
    Series title Studies in fuzziness and soft computing ; 232
    Collection
    Keywords Epidemiologie ; Fuzzy-Logik ; Soft Computing
    Subject Softcomputing ; Computational Intelligence ; Krankheitsverbreitung ; Unscharfe Logik ; Qualitativaussagenlogik ; Vage Logik ; Fuzzy logic ; Fuzzylogic
    Subject code 614.4028563
    Language English
    Size XII, 347 S. : Ill., graph. Darst., 25 cm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    Note Literaturverz. S. 313 - 333
    HBZ-ID HT016177210
    ISBN 978-3-540-69092-4 ; 3-540-69092-1
    Database Catalogue ZB MED Medicine, Health

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  3. Article ; Online: Measles and human movement in Europe.

    Massad, Eduardo

    Journal of travel medicine

    2018  Volume 25, Issue 1

    MeSH term(s) Disease Eradication/organization & administration ; Disease Outbreaks/prevention & control ; Europe/epidemiology ; Humans ; Measles/epidemiology ; Measles/prevention & control ; Measles Vaccine/therapeutic use ; Measles-Mumps-Rubella Vaccine/therapeutic use ; Social Determinants of Health ; Travel ; Vaccination/statistics & numerical data
    Chemical Substances Measles Vaccine ; Measles-Mumps-Rubella Vaccine
    Language English
    Publishing date 2018-11-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/tay091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effects of migration rates and vaccination on the spread of yellow fever in Latin American communities.

    Simon, Sabrina / Amaku, Marcos / Massad, Eduardo

    Revista panamericana de salud publica = Pan American journal of public health

    2023  Volume 47, Page(s) e86

    Abstract: Objective: To assess how relevant the flow of people between communities is, compared to vaccination and type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community.: Methods: Using a SEIRV-SEI model for ... ...

    Abstract Objective: To assess how relevant the flow of people between communities is, compared to vaccination and type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community.
    Methods: Using a SEIRV-SEI model for humans and vectors, we applied numerical simulations to the scenarios: (1) migration from an endemic community to a disease-free host community, comparing the performance of
    Results: Results show no remarkable differences between scenarios 1 and 2. The type of vector and vaccination coverage in the host community are more relevant for the occurrence of outbreaks than migration rates, with
    Conclusions: With vaccination being more determinant for a potential outbreak than migration rates, vaccinating migrants on arrival may be one of the most effective measures against yellow fever. Furthermore,
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1376934-0
    ISSN 1680-5348 ; 1020-4989
    ISSN (online) 1680-5348
    ISSN 1020-4989
    DOI 10.26633/RPSP.2023.86
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Effects of migration rates and vaccination on the spread of yellow fever in Latin American communities

    Sabrina Simon / Marcos Amaku / Eduardo Massad

    Revista Panamericana de Salud Pública, Vol 47, Iss 86, Pp 1-

    2023  Volume 10

    Abstract: Objective. To assess how relevant the flow of people between communities is, compared to vaccination and type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community. Methods. Using a SEIRV-SEI model for humans ... ...

    Abstract Objective. To assess how relevant the flow of people between communities is, compared to vaccination and type of vector, on the spread and potential outbreaks of yellow fever in a disease-free host community. Methods. Using a SEIRV-SEI model for humans and vectors, we applied numerical simulations to the scenarios: (1) migration from an endemic community to a disease-free host community, comparing the performance of Haemagogus janthinomys and Aedes aegypti as vectors; (2) migration through a transit community located on a migratory route, where the disease is endemic, to a disease-free one; and (3) effects of different vaccination rates in the host community, considering the vaccination of migrants upon arrival. Results. Results show no remarkable differences between scenarios 1 and 2. The type of vector and vaccination coverage in the host community are more relevant for the occurrence of outbreaks than migration rates, with H. janthinomys being more effective than A. aegypti. Conclusions. With vaccination being more determinant for a potential outbreak than migration rates, vaccinating migrants on arrival may be one of the most effective measures against yellow fever. Furthermore, H. janthinomys is a more competent vector than A. aegypti at similar densities, but the presence of A. aegypti is a warning to maintain vaccination above recommended levels.
    Keywords yellow fever ; vaccination ; human migration ; epidemiological models ; public health ; vector borne diseases ; disease outbreaks ; latin america ; Medicine ; R ; Arctic medicine. Tropical medicine ; RC955-962 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Pan American Health Organization
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Burden of Yellow Fever on Migrating Humans through The Darién Gap, Adjacent Communities, and Primates’ Biodiversity

    Sabrina Simon / Marcos Amaku / Eduardo Massad

    Challenges, Vol 14, Iss 4, p

    2023  Volume 52

    Abstract: Given the ongoing migratory crisis in Latin America, we aimed to assess the relationship between human mobility and the spread of yellow fever (YF) in the Darién Gap forest. We investigated how the time taken to cross the forest affects the burden of a ... ...

    Abstract Given the ongoing migratory crisis in Latin America, we aimed to assess the relationship between human mobility and the spread of yellow fever (YF) in the Darién Gap forest. We investigated how the time taken to cross the forest affects the burden of a potential YF outbreak on people migrating through the forest, the burden on adjacent communities, and the risk to primate biodiversity. Using an SEIR-SEI deterministic compartmental model for humans, monkeys, and vectors, and numerical simulations, we considered the time taken to cross the forest as a measure of exposure. If an outbreak occurs, over 23,000 human cases are projected, with approximately 19,000 infected individuals leaving the forest. Monkeys would also be significantly affected, with the number of human deaths being determined by monkey-related parameters. The pace of crossing the forest is strongly related to the number of exposed and active cases leaving the forest. Panamanian communities must receive support to prepare themselves to protect residents and thousands of people arriving in their territory daily. It would also impact the non-human primate community within the forest, preventing a YF outbreak. This reinforces the importance of a planetary health perspective which reinforces the mutual benefits and connections between efforts to protect human health and conserve biodiversity.
    Keywords epizootic diseases ; infectious diseases ; re-emerging diseases ; migration ; mathematical modeling ; Technology ; T ; Science (General) ; Q1-390
    Subject code 910
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A novel eco-friendly polymeric photosensitizer based on chitosan and flavin mononucleotide.

    Sacchetto, Julieta / Gutierrez, Eduardo / Reta, Guillermo F / Gatica, Eduardo / Miskoski, Sandra / Montaña, María P / Natera, José / Massad, Walter A

    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology

    2023  Volume 22, Issue 12, Page(s) 2827–2837

    Abstract: Flavin mononucleotide (FMN) is a dye belonging to the flavin family. These dyes produce photosensitized degradation of organic compounds via reaction with the excited states of the dye or with reactive oxygen species photogenerated from the triplet of ... ...

    Abstract Flavin mononucleotide (FMN) is a dye belonging to the flavin family. These dyes produce photosensitized degradation of organic compounds via reaction with the excited states of the dye or with reactive oxygen species photogenerated from the triplet of the dye. This article presents a new polymeric dye (FMN-CS) composed of the photosensitizer FMN covalently bonded to chitosan polysaccharide (CS). FMN-CS obtained has a molecular weight of 230 × 10
    MeSH term(s) Photosensitizing Agents/chemistry ; Flavin Mononucleotide/chemistry ; Chitosan ; Flavins/chemistry ; Reactive Oxygen Species
    Chemical Substances Photosensitizing Agents ; Flavin Mononucleotide (7N464URE7E) ; Chitosan (9012-76-4) ; Flavins ; Reactive Oxygen Species
    Language English
    Publishing date 2023-10-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2072584-X
    ISSN 1474-9092 ; 1474-905X
    ISSN (online) 1474-9092
    ISSN 1474-905X
    DOI 10.1007/s43630-023-00489-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: THE OPTIMUM LEVEL OF MELD TO MINIMIZE THE MORTALITY ON LIVER TRANSPLANTATION WAITING LIST, AND LIVER TRANSPLANTED PATIENT IN SÃO PAULO STATE, BRAZIL.

    Chaib, Eleazar / Pessoa, João Luiz Erbs / Struchiner, Claudio José / D'Albuquerque, Luiz Augusto Carneiro / Massad, Eduardo

    Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery

    2023  Volume 36, Page(s) e1746

    Abstract: Background: After validation in multiple types of liver disease patients, the MELD score was adopted as a standard by which liver transplant candidates with end-stage liver disease were prioritized for organ allocation in the United States since 2002, ... ...

    Abstract Background: After validation in multiple types of liver disease patients, the MELD score was adopted as a standard by which liver transplant candidates with end-stage liver disease were prioritized for organ allocation in the United States since 2002, and in Brazil, since 2006.
    Aims: To analyze the mortality profile of patients on the liver transplant waiting list correlated to MELD score at the moment of transplantation.
    Methods: This study used the data from the Secretary of Health of the São Paulo State, Brazil, which listed 22,522 patients, from 2006 (when MELD score was introduced in Brazil) until June 2009. Patients with acute hepatic failure and tumors were included as well. We also considered the mortality of both non-transplanted and transplanted patients as a function of the MELD score at presentation.
    Results: Our model showed that the best MELD score for patients on the liver transplant waiting list associated to better results after liver transplantation was 26.
    Conclusions: We found that the best score for applying to liver transplant waiting list in the State of São Paulo was 26. This is the score that minimizes the mortality in both non-transplanted and liver transplanted patients.
    MeSH term(s) Humans ; Liver Transplantation ; Brazil ; Waiting Lists ; End Stage Liver Disease/surgery
    Language English
    Publishing date 2023-09-15
    Publishing country Brazil
    Document type Journal Article
    ISSN 2317-6326
    ISSN (online) 2317-6326
    DOI 10.1590/0102-672020230028e1746
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Riboflavin and Eosin Y Supported on Chromatographic Silica Gel as Heterogeneous Photocatalysts.

    Caminos, Daniel A / Rimondino, Guido N / Gatica, Eduardo / Massad, Walter A / Argüello, Juan E

    ACS omega

    2023  Volume 8, Issue 33, Page(s) 30705–30715

    Abstract: The application of photocatalysis for organic synthesis, both in the laboratory and on an industrial scale, will depend on the achieving of good yields and the ease with which it can be applied. Selective irradiation of the photocatalyst with LED light ... ...

    Abstract The application of photocatalysis for organic synthesis, both in the laboratory and on an industrial scale, will depend on the achieving of good yields and the ease with which it can be applied. Selective irradiation of the photocatalyst with LED light has made it possible to activate the reactions easily, without the need for UV or heat filters. However, a common problem is the need to separate the photocatalyst from the reaction products through extraction and chromatography isolation processes. These procedures make it difficult to recover and reuse the catalyst, which is not compatible with scale-up applications. Photocatalysts attached to heterogeneous supports resulted in an alternative, which facilitates their removal and reuse. In this study, we use chromatographic silica gel as a low-cost heterogeneous support to bind photosensitizers such as Riboflavin or Eosin Y. The modified silica gel was analyzed by FTIR-ATR and diffuse reflectance UV-visible spectroscopy, thermogravimetric analysis, and optical microscopy. These hybrid materials have a suitable size for easy separation by decantation and were found to be photoactive against two photooxidation reactions. These easy-to-handle materials open the door to effective applications for photoinduced organic synthesis methods at medium to large scale.
    Language English
    Publishing date 2023-08-09
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c04622
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: COVID-19 underreporting and its impact on vaccination strategies.

    Albani, Vinicius / Loria, Jennifer / Massad, Eduardo / Zubelli, Jorge

    BMC infectious diseases

    2021  Volume 21, Issue 1, Page(s) 1111

    Abstract: Background: Underreporting cases of infectious diseases poses a major challenge in the analysis of their epidemiological characteristics and dynamical aspects. Without accurate numerical estimates it is difficult to precisely quantify the proportions of ...

    Abstract Background: Underreporting cases of infectious diseases poses a major challenge in the analysis of their epidemiological characteristics and dynamical aspects. Without accurate numerical estimates it is difficult to precisely quantify the proportions of severe and critical cases, as well as the mortality rate. Such estimates can be provided for instance by testing the presence of the virus. However, during an ongoing epidemic, such tests' implementation is a daunting task. This work addresses this issue by presenting a methodology to estimate underreported infections based on approximations of the stable rates of hospitalization and death.
    Methods: We present a novel methodology for the stable rate estimation of hospitalization and death related to the Corona Virus Disease 2019 (COVID-19) using publicly available reports from various distinct communities. These rates are then used to estimate underreported infections on the corresponding areas by making use of reported daily hospitalizations and deaths. The impact of underreporting infections on vaccination strategies is estimated under different disease-transmission scenarios using a Susceptible-Exposed-Infective-Removed-like (SEIR) epidemiological model.
    Results: For the considered locations, during the period of study, the estimations suggest that the number of infected individuals could reach 30% of the population of these places, representing, in some cases, more than six times the observed numbers. These results are in close agreement with estimates from independent seroprevalence studies, thus providing a strong validation of the proposed methodology. Moreover, the presence of large numbers of underreported infections can reduce the perceived impact of vaccination strategies in reducing rates of mortality and hospitalization.
    Conclusions: pBy using the proposed methodology and employing a judiciously chosen data analysis implementation, we estimate COVID-19 underreporting from publicly available data. This leads to a powerful way of quantifying underreporting impact on the efficacy of vaccination strategies. As a byproduct, we evaluate the impact of underreporting in the designing of vaccination strategies.
    MeSH term(s) COVID-19 ; Hospitalization ; Humans ; SARS-CoV-2 ; Seroepidemiologic Studies ; Vaccination
    Language English
    Publishing date 2021-10-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-021-06780-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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