Book ; Online: T Cell Regulation by the Environment
2015
Abstract: Naïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and ... ...
| Abstract | Naïve T cells get activated upon encounter with their cognate antigen and differentiate into a specific subset of effector cells. These T cells are themselves plastic and are able to re-differentiate into another subset, changing both phenotype and function. Differentiation into a specific subset depends on the nature of the antigen and of the environmental milieu. Notably, certain nutrients, such as vitamins A and D, sodium chloride, have been shown to modulate T cell responses and influence T cell differentiation. Parasite infection can also skew Th differentiation. Similarly, the gut microbiota regulates the development of immune responses. Lastly, the key role of metabolism on T cells has also been demonstrated. This series of articles highlights some of the multiple links existing between environmental factors and T cell responses |
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| Keywords | Immunologic diseases. Allergy ; Medicine (General) |
| Size | 1 electronic resource (115 p.) |
| Publisher | Frontiers Media SA |
| Document type | Book ; Online |
| Note | English ; Open Access |
| HBZ-ID | HT020091162 |
| ISBN | 9782889197330 ; 2889197336 |
| Database | ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture |
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