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  1. Book ; Online: Lithium-ion Batteries : Thin Film for Energy Materials and Devices

    Sato, Mitsunobu / Lu, Li / Nagai, Hiroki

    2020  

    Keywords Electrical engineering
    Size 1 electronic resource (132 pages)
    Publisher IntechOpen
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021049024
    ISBN 9781839622977 ; 1839622970
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Texture statistics involved in specular highlight exclusion for object lightness perception.

    Nohira, Hiroki / Nagai, Takehiro

    Journal of vision

    2023  Volume 23, Issue 3, Page(s) 1

    Abstract: The human visual system estimates the physical properties of objects, such as their lightness. Previous studies on the lightness perception of glossy three-dimensional objects have suggested that specular highlights are detected and excluded in lightness ...

    Abstract The human visual system estimates the physical properties of objects, such as their lightness. Previous studies on the lightness perception of glossy three-dimensional objects have suggested that specular highlights are detected and excluded in lightness perception. However, only a few studies have attempted to elucidate the mechanisms underlying this exclusion. This study aimed to elucidate the image features that contribute to the highlight exclusion of lightness perception. We used Portilla-Simoncelli texture statistics (PS statistics), an image feature set similar to the representation in the early visual cortex, to explore their relationships with highlight exclusion for lightness perception. In experiment 1, computer graphics images of bumpy plastic plates with various physical parameters were used as stimuli, and the lightness perception on them was measured using a lightness matching task. We then calculated the highlight exclusion index, which represented the degree of highlight exclusion. Finally, we evaluated the correlation between the highlight exclusion index and the four PS statistic subsets. In experiment 2, an image synthesis algorithm was used to create images in which either the PS statistic subset was manipulated. The highlight exclusion indexes of the synthesized images were then measured. The results revealed that the PS statistic subset consisting of lowest-order image features, such as moment statistics of luminance, acts as a necessary condition for highlight exclusion, whereas the other three subsets consisting of higher order features are not crucial. These results suggest that the low-order image features are the most important among the features in PS statistics for highlight exclusion, even though image features higher order than those in PS statistics must be directly involved.
    MeSH term(s) Humans ; Algorithms ; Computer Graphics ; Perception
    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2106064-2
    ISSN 1534-7362 ; 1534-7362
    ISSN (online) 1534-7362
    ISSN 1534-7362
    DOI 10.1167/jov.23.3.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Miniaturization of CRISPR/Cas12-Based DNA Sensor Array by Non-Contact Printing.

    Shigemori, Hiroki / Fujita, Satoshi / Tamiya, Eiichi / Nagai, Hidenori

    Micromachines

    2024  Volume 15, Issue 1

    Abstract: DNA microarrays have been applied for comprehensive genotyping, but remain a drawback in complicated operations. As a solution, we previously reported the solid-phase collateral cleavage (SPCC) system based on the clustered regularly interspaced short ... ...

    Abstract DNA microarrays have been applied for comprehensive genotyping, but remain a drawback in complicated operations. As a solution, we previously reported the solid-phase collateral cleavage (SPCC) system based on the clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 12 (CRISPR/Cas12). Surface-immobilized Cas12-CRISPR RNA (crRNA) can directly hybridize target double-stranded DNA (dsDNA) and subsequently produce a signal via the cleavage of single-stranded DNA (ssDNA) reporter immobilized on the same spot. Therefore, SPCC-based multiplex dsDNA detection can be performed easily. This study reports the miniaturization of SPCC-based spots patterned by a non-contact printer and its performance in comprehensive genotyping on a massively accumulated array. Initially, printing, immobilization, and washing processes of Cas12-crRNA were established to fabricate the non-contact-patterned SPCC-based sensor array. A target dsDNA concentration response was obtained based on the developed sensor array, even with a spot diameter of 0.64 ± 0.05 mm. Also, the limit of detection was 572 pM, 531 pM, and 3.04 nM with 40, 20, and 10 nL-printing of Cas12-crRNA, respectively. Furthermore, the sensor array specifically detected three dsDNA sequences in one-pot multiplexing; therefore, the feasibility of comprehensive genotyping was confirmed. These results demonstrate that our technology can be miniaturized as a CRISPR/Cas12-based microarray by using non-contact printing. In the future, the non-contact-patterned SPCC-based sensor array can be applied as an alternative tool to DNA microarrays.
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi15010144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Visible-light-induced superhydrophilicity of crystallized WO

    Murayama, Taichi / Sato, Mitsunobu / Nagai, Hiroki / Yasui, Eiko

    Nanoscale advances

    2023  Volume 5, Issue 7, Page(s) 1990–1998

    Abstract: Transparent tungsten trioxide thin films, which demonstrated visible-light (Vis-light)-induced superhydrophilicity, with thicknesses of 100-120 nm, adhesion strengths greater than 49 MPa, bandgap energies of 2.8-2.9 eV, and haze values of 0.4-0.5%, were ... ...

    Abstract Transparent tungsten trioxide thin films, which demonstrated visible-light (Vis-light)-induced superhydrophilicity, with thicknesses of 100-120 nm, adhesion strengths greater than 49 MPa, bandgap energies of 2.8-2.9 eV, and haze values of 0.4-0.5%, were fabricated using a solution-based process on quartz glass substrates. The precursor solution was prepared by dissolving a W
    Language English
    Publishing date 2023-03-07
    Publishing country England
    Document type Journal Article
    ISSN 2516-0230
    ISSN (online) 2516-0230
    DOI 10.1039/d2na00717g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Selective autophagy tolerates symbiotic bacteria in the

    Nagai, Hiroki / Yano, Tamaki

    Autophagy

    2021  Volume 17, Issue 4, Page(s) 1057–1058

    Abstract: Intestinal epithelium functions as a barrier to protect the host from environmental microbes. Defects in macroautophagy/autophagy combined with intestinal microbes cause a disruption of homeostasis of the tissue, which is associated with the etiology of ... ...

    Abstract Intestinal epithelium functions as a barrier to protect the host from environmental microbes. Defects in macroautophagy/autophagy combined with intestinal microbes cause a disruption of homeostasis of the tissue, which is associated with the etiology of Crohn disease, an inflammatory bowel disease. However, the molecular mechanism of how autophagy interacts with microbes in the pathology are mostly unrevealed. Our recent findings using
    MeSH term(s) Animals ; Autophagy ; Bacteria ; Drosophila ; Homeostasis ; Macroautophagy ; Reactive Oxygen Species
    Chemical Substances Reactive Oxygen Species
    Language English
    Publishing date 2021-04-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2454135-7
    ISSN 1554-8635 ; 1554-8627
    ISSN (online) 1554-8635
    ISSN 1554-8627
    DOI 10.1080/15548627.2021.1904490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6741: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Lethal calcification at aortic valve annulus: a multi-edged sword.

    Kawahara, Yo / Nagai, Tomoo / Moroe, Shota / Takeuchi, Hiroki

    Journal of echocardiography

    2022  Volume 21, Issue 3, Page(s) 138–139

    MeSH term(s) Humans ; Aortic Valve/diagnostic imaging ; Aortic Valve/surgery ; Aortic Valve Stenosis/diagnostic imaging ; Aortic Valve Stenosis/surgery ; Calcinosis/diagnosis ; Calcinosis/diagnostic imaging ; Heart Valve Prosthesis
    Language English
    Publishing date 2022-06-24
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2209473-8
    ISSN 1880-344X ; 1349-0222
    ISSN (online) 1880-344X
    ISSN 1349-0222
    DOI 10.1007/s12574-022-00580-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Bacterial usurpation of the OTU deubiquitinase fold.

    Pruneda, Jonathan N / Nguyen, Justine V / Nagai, Hiroki / Kubori, Tomoko

    The FEBS journal

    2023  

    Abstract: The extensive cellular signalling events controlled by posttranslational ubiquitination are tightly regulated through the action of specialized proteases termed deubiquitinases. Among them, the OTU family of deubiquitinases can play very specialized ... ...

    Abstract The extensive cellular signalling events controlled by posttranslational ubiquitination are tightly regulated through the action of specialized proteases termed deubiquitinases. Among them, the OTU family of deubiquitinases can play very specialized roles in the regulation of discrete subtypes of ubiquitin signals that control specific cellular functions. To exert control over host cellular functions, some pathogenic bacteria have usurped the OTU deubiquitinase fold as a secreted virulence factor that interferes with ubiquitination inside infected cells. Herein, we provide a review of the function of bacterial OTU deubiquitinases during infection, the structural basis for their deubiquitinase activities and the bioinformatic approaches leading to their identification. Understanding bacterial OTU deubiquitinases holds the potential for discoveries not only in bacterial pathogenesis but in eukaryotic biology as well.
    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2173655-8
    ISSN 1742-4658 ; 1742-464X
    ISSN (online) 1742-4658
    ISSN 1742-464X
    DOI 10.1111/febs.16725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 260: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Four Cases of Delayed Pneumonia Around Coils After Embolization of Pulmonary Arteriovenous Malformations.

    Tanaka, Kaishu / Osuga, Keigo / Nagai, Keisuke / Satomura, Hiroki / Tomotake, Kosuke / Koretsune, Yuji / Kimura, Yasushi / Ono, Yusuke / Higashihara, Hiroki / Tomiyama, Noriyuki

    Cardiovascular and interventional radiology

    2023  Volume 47, Issue 3, Page(s) 397–400

    MeSH term(s) Humans ; Arteriovenous Malformations/diagnostic imaging ; Arteriovenous Malformations/therapy ; Arteriovenous Fistula/therapy ; Pulmonary Veins/diagnostic imaging ; Pulmonary Veins/abnormalities ; Pulmonary Artery/diagnostic imaging ; Pulmonary Artery/abnormalities ; Pneumonia ; Embolization, Therapeutic/adverse effects
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Letter
    ZDB-ID 603082-8
    ISSN 1432-086X ; 0342-7196 ; 0174-1551
    ISSN (online) 1432-086X
    ISSN 0342-7196 ; 0174-1551
    DOI 10.1007/s00270-023-03588-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1378: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Cellular mechanisms underlying adult tissue plasticity in

    Nagai, Hiroki / Miura, Masayuki / Nakajima, Yu-Ichiro

    Fly

    2022  Volume 16, Issue 1, Page(s) 190–206

    Abstract: Adult tissues in Metazoa dynamically remodel their structures in response to environmental challenges including sudden injury, pathogen infection, and nutritional fluctuation, while maintaining quiescence under homoeostatic conditions. This ... ...

    Abstract Adult tissues in Metazoa dynamically remodel their structures in response to environmental challenges including sudden injury, pathogen infection, and nutritional fluctuation, while maintaining quiescence under homoeostatic conditions. This characteristic, hereafter referred to as adult tissue plasticity, can prevent tissue dysfunction and improve the fitness of organisms in continuous and/or severe change of environments. With its relatively simple tissue structures and genetic tools, studies using the fruit fly
    MeSH term(s) Adaptation, Physiological ; Animals ; Cell Differentiation ; Drosophila/physiology ; Drosophila melanogaster/genetics ; Homeostasis/physiology
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ISSN 1933-6942
    ISSN (online) 1933-6942
    DOI 10.1080/19336934.2022.2066952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Investigation of Formulations on Pyrene-Based Anodized-Aluminum Pressure-Sensitive Paints for Supersonic Phenomena.

    Yomo, Kazuma / Ikami, Tsubasa / Fujita, Koji / Nagai, Hiroki

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 12

    Abstract: Pressure-sensitive paint (PSP) is an optical sensor that can measure global pressure distribution by using the oxygen quenching of dye molecules. In particular, anodized aluminum pressure-sensitive paint (AA-PSP) exhibits a fast time response. AA-PSP has ...

    Abstract Pressure-sensitive paint (PSP) is an optical sensor that can measure global pressure distribution by using the oxygen quenching of dye molecules. In particular, anodized aluminum pressure-sensitive paint (AA-PSP) exhibits a fast time response. AA-PSP has been used in unsteady measurements at supersonic and transonic speeds, such as on the surface of a transonic free-flying sphere or the wall of a shock tube when the shock wave passes. To capture such ultrafast phenomena, the frame rate of the camera must be sufficiently fast, and the exposure time must be sufficiently short. Therefore, it is desirable that the AA-PSP exhibits bright luminescence, high-pressure sensitivity, and fast response time. This study focused on pyrene-based AA-PSPs and investigated their characteristics, such as luminescence intensity and pressure sensitivity, at different anodization times, dipping solvents, and dipping concentrations. Furthermore, a time-response test using a shock tube was conducted on the brightest AA-PSP. Consequently, the time for a 90% rise in pressure was 2.2 μs.
    Language English
    Publishing date 2022-06-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22124430
    Database MEDical Literature Analysis and Retrieval System OnLINE

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