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  1. Article: Klyuchevye stomatologicheskie problemy perioda pandemii COVID-19: monitoring sostoyaniya stomatologicheskogo zdorov'ya u patsientov s khronicheskimi zabolevaniyami slizistoi obolochki polosti rta.

    Gileva, O S / Libik, T V / Gibadullina, N V / Sivak, E Yu / Gavrilenko, M S / Beleva, N S / Zadorina, I I

    Stomatologiia

    2022  Volume 100, Issue 6. Vyp. 2, Page(s) 8–15

    Abstract: Objective: To develop an effective system of an interactive dynamic telemonitoring of oral health in patients with oral lichen planus (LP) during the COVID-19 pandemic.: Material and methods: The observational longitudinal prospective cohort study ( ... ...

    Title translation Key dental challenges during COVID-19 pandemic: oral health monitoring in patients with chronic oral mucosal diseases.
    Abstract Objective: To develop an effective system of an interactive dynamic telemonitoring of oral health in patients with oral lichen planus (LP) during the COVID-19 pandemic.
    Material and methods: The observational longitudinal prospective cohort study (follow-up for 12 months) involved 53 patients (19 men and 34 women aged 49-65 years) with various forms of LP in persistent remission. During the entire observation period dentists carried out telemonitoring (through a Telegram group) of oral health of patients with LP registering the preservation/coming out from remission, as well as the causes of exacerbation of LP.
    Results: The developed interactive monitoring system based on the use of available video feedback communication technologies (via Telegram, WhatsApp, Viber messengers) provided stable remission in 28.3% of patients with LP (mainly typical and hyperkeratotic forms) and effective relief of exacerbations (mainly erosive-ulcerative forms) associated with the new coronavirus infection COVID-19 in 35.8% of cases, exacerbation of concomitant systemic pathology (excluding COVID-19) in 16.9%, local traumatic risk factors in 15.1%, development of post-vaccination reactions in 3.9%. COVID-19-associated exacerbation of LP is a polymorphic symptom complex manifested by a change in classical clinical picture and heavier course of skin-mucosal dermatosis due to the addition of new, atypical for LP, manifested COVID-19-associated intraoral symptoms and generalization of skin lesions. Periods of exacerbation of LP in COVID-19 patients are significantly longer, with shorter remissions than in the prepandemic period.
    Conclusion: Interactive telemonitoring of oral health in patients with chronic oral mucosal diseases is a safe and effective tool for dispensary observation, management and maintenance of social communications during periods of social isolation.
    MeSH term(s) Aged ; COVID-19 ; Female ; Humans ; Lichen Planus, Oral ; Male ; Middle Aged ; Oral Health ; Pandemics ; Prospective Studies ; SARS-CoV-2
    Language Russian
    Publishing date 2022-01-26
    Publishing country Russia (Federation)
    Document type Journal Article ; Observational Study
    ZDB-ID 421717-2
    ISSN 0039-1735
    ISSN 0039-1735
    DOI 10.17116/stomat20211000628
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  2. Article ; Online: The cause(s) of myopia and the efforts that have been made to prevent it.

    Sivak, Jacob

    Clinical & experimental optometry

    2012  Volume 95, Issue 6, Page(s) 572–582

    Abstract: ... attention, the cause(s) and the means of preventing or mitigating the progression of myopia in children are ...

    Abstract In spite of a long history of study, as well as a significant, recent increase in research attention, the cause(s) and the means of preventing or mitigating the progression of myopia in children are still elusive. The high and growing prevalence of myopia, especially in Asian populations, as well as its progressive nature in children and its effect on visual acuity, have contributed to the recent surge in interest. Animal research carried out in the 1970s also helped spark this interest by legitimising the study of environmental influences on the refractive development of the eye. Efforts that include the use of visual training or biofeedback, bifocal and progressive lenses, contact lenses and pharmaceuticals are reviewed. Current research trends that focus on the relationship between genetics and environment, as well as studies, both animal and human, that explore the effect of peripheral refractive error on the refractive development of the central retina are also reviewed.
    MeSH term(s) Contact Lenses ; Disease Progression ; Eyeglasses ; Humans ; Myopia/etiology ; Myopia/physiopathology ; Myopia/prevention & control ; Optometry/methods ; Refraction, Ocular ; Visual Acuity
    Language English
    Publishing date 2012-11
    Publishing country Australia
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639275-1
    ISSN 1444-0938 ; 0816-4622
    ISSN (online) 1444-0938
    ISSN 0816-4622
    DOI 10.1111/j.1444-0938.2012.00781.x
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  3. Article ; Online: A note: the changing gender demographics of U.S. drivers.

    Sivak, Michael / Schoettle, Brandon

    Traffic injury prevention

    2012  Volume 13, Issue 6, Page(s) 575–576

    Abstract: ... data from the Federal Highway Administration and the U.S. Census Bureau.: Results: There are 2 main ...

    Abstract Objective: This study examined recent trends in gender differences in the percentage of persons with driver's licenses as a function of age by comparing data from 2010 and 1995.
    Method: The analysis used data from the Federal Highway Administration and the U.S. Census Bureau.
    Results: There are 2 main findings. First, the percentage of males with a driver's license decreased from 1995 to 2010 for those younger than 60; for females a decrease occurred for those younger than 50. Second, in 2010, proportionally more males younger than 45 had a driver's license than was the case for females; the opposite relationship held for persons 45 and older.
    Conclusions: The observed gender trends in driver licensing will likely have major implications on the extent and nature of vehicle demand, energy consumption, and road safety.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Automobile Driving/legislation & jurisprudence ; Female ; Humans ; Licensure/trends ; Male ; Middle Aged ; Sex Distribution ; United States ; Young Adult
    Language English
    Publishing date 2012
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2012.727110
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  4. Article ; Online: An analysis of U.S. road fatalities per population: changes by age from 1958 to 2008.

    Sivak, Michael / Schoettle, Brandon

    Traffic injury prevention

    2011  Volume 12, Issue 5, Page(s) 438–442

    Abstract: Objective: This article presents a time-series analysis of changes in road safety in the United States from a public-health point of view.: Method: A 50-year period was examined, from 1958 to 2008. The emphasis was on the changes by decades in ... ...

    Abstract Objective: This article presents a time-series analysis of changes in road safety in the United States from a public-health point of view.
    Method: A 50-year period was examined, from 1958 to 2008. The emphasis was on the changes by decades in fatalities per population across different age groups.
    Results: First, from 1958 to 2008, the overall fatality rate per population decreased by 40 percent. Second, the decrease in the rate was age dependent (with the largest decreases for the youngest and the oldest, and the smallest decreases for the middle-aged). Third, the overall fatality rate increased from 1958 to 1968, but it decreased for each of the 4 following decades. Fourth, the changes in the rate for each decade were age dependent. Fifth, the patterns of these age-dependent changes varied across the decades.
    Conclusions: Examples of interventions that are likely to have age-dependent effects consistent with the obtained differential age changes in the fatality rate are discussed. However, other interventions are also likely to have relevant age-dependent effects on the fatality rate.
    MeSH term(s) Accidents, Traffic/mortality ; Accidents, Traffic/trends ; Adolescent ; Adult ; Age Distribution ; Aged ; Child ; Child, Preschool ; Humans ; Middle Aged ; Safety ; United States/epidemiology ; Young Adult
    Language English
    Publishing date 2011-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2011.588980
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Toward understanding the recent large reductions in U.S. road fatalities.

    Sivak, Michael / Schoettle, Brandon

    Traffic injury prevention

    2010  Volume 11, Issue 6, Page(s) 561–566

    Abstract: Background: From 2005 to 2009, U.S. road fatalities dropped by 22 percent (from 43,510 to 33,963 ... System (FARS)-a census of all U.S. crashes that involve a fatality.: Method: The study compared ...

    Abstract Background: From 2005 to 2009, U.S. road fatalities dropped by 22 percent (from 43,510 to 33,963). A reduction of such magnitude over such a short time has not occurred since road safety statistics were first kept (starting in 1913), except for the reductions during World War II.
    Objective: The study was performed to contribute to our understanding about the mechanisms that could be responsible for this unprecedented drop in road fatalities by analyzing the detailed information from the Fatality Analysis Reporting System (FARS)-a census of all U.S. crashes that involve a fatality.
    Method: The study compared the data for 2005 (the recent peak year in terms of road fatalities) with the data for 2008 (the latest year for which detailed data are available). The focus was on identifying those conditions that showed the largest reductions and those that showed the smallest reductions (or increases of any magnitude). The analysis involved an examination of the variables in the FARS database, which is divided into accident, vehicle, driver, occupant, and nonmotorist subsets.
    Results: The report highlights the most interesting patterns of changes for 19 variables.
    MeSH term(s) Accidents, Traffic/mortality ; Accidents, Traffic/trends ; Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Alcoholic Intoxication/epidemiology ; Automobile Driving/legislation & jurisprudence ; Automobile Driving/statistics & numerical data ; Databases, Factual ; Humans ; Middle Aged ; Motor Vehicles/statistics & numerical data ; Time Factors ; United States/epidemiology ; Young Adult
    Language English
    Publishing date 2010-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2010.520140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Recent changes in the age composition of U.S. drivers: implications for the extent, safety, and environmental consequences of personal transportation.

    Sivak, Michael / Schoettle, Brandon

    Traffic injury prevention

    2011  Volume 12, Issue 6, Page(s) 588–592

    Abstract: Objective: This study examined the changes in the United States from 1983 to 2008 in the percentage of persons with driver's licenses as a function of age.: Method: The analysis used data from the Federal Highway Administration on driver's licenses ... ...

    Abstract Objective: This study examined the changes in the United States from 1983 to 2008 in the percentage of persons with driver's licenses as a function of age.
    Method: The analysis used data from the Federal Highway Administration on driver's licenses by age.
    Results: (1) Over the past 25 years, there was a substantial decrease in the percentage of young people with a driver's license and a substantial increase in the percentage of older people with a driver's license. (2) For cohorts who were between age 20 and 44 in 1983 (and thus between age 45 and 69 in 2008), the percentage of licensed drivers has not changed appreciably between 1983 and 2008. This finding suggests that, for all practical purposes, all those who wanted to obtain a driver's license did so by age 20. (3) For cohorts who were between age 45 and 59 in 1983 (and thus between age 70 and 84 in 2008), this percentage dropped substantially. This finding reflects the surrendering of driver's licenses with advanced age.
    Conclusion: The age composition of US drivers has changed substantially between 1983 and 2008. In 1983, the largest group of drivers included those between 25 and 29 years of age. In contrast, in 2008, the largest group included those 70 years and older.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Automobile Driving/statistics & numerical data ; Cohort Studies ; Environment Design ; Humans ; Licensure/trends ; Middle Aged ; Safety ; Transportation/methods ; Transportation/statistics & numerical data ; United States ; Young Adult
    Language English
    Publishing date 2011-12
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2089818-6
    ISSN 1538-957X ; 1538-9588
    ISSN (online) 1538-957X
    ISSN 1538-9588
    DOI 10.1080/15389588.2011.605817
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  7. Article ; Online: Optimal control with a strong harmonic trap.

    Blaber, Steven / Sivak, David A

    Physical review. E

    2022  Volume 106, Issue 2, Page(s) L022103

    Abstract: Quadratic trapping potentials are widely used to experimentally probe biopolymers and molecular machines and drive transitions in steered molecular-dynamics simulations. Approximating energy landscapes as locally quadratic, we design multidimensional ... ...

    Abstract Quadratic trapping potentials are widely used to experimentally probe biopolymers and molecular machines and drive transitions in steered molecular-dynamics simulations. Approximating energy landscapes as locally quadratic, we design multidimensional trapping protocols that minimize dissipation. The designed protocols are easily solvable and applicable to a wide range of systems. The approximation does not rely on either fast or slow limits and is valid for any duration provided the trapping potential is sufficiently strong. We demonstrate the utility of the designed protocols with a simple model of a periodically driven rotary motor. Our results elucidate principles of effective single-molecule manipulation and efficient nonequilibrium free-energy estimation.
    Language English
    Publishing date 2022-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.106.L022103
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  8. Article ; Online: Gastrointestinal Complications of Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS) Syndrome Managed By Parenteral Nutrition.

    Horná, Simona / Péč, Martin Jozef / Krivuš, Juraj / Michalová, Renáta / Sivák, Štefan / Galajda, Peter / Mokáň, Marián

    European journal of case reports in internal medicine

    2024  Volume 11, Issue 2, Page(s) 4268

    Abstract: MELAS - an acronym for mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes - is a multiorgan disease caused by a mutation in mitochondrial DNA (mtDNA). Its clinical manifestations are highly variable; mainly stroke-like episodes, ... ...

    Abstract MELAS - an acronym for mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes - is a multiorgan disease caused by a mutation in mitochondrial DNA (mtDNA). Its clinical manifestations are highly variable; mainly stroke-like episodes, seizures, recurrent headaches, or muscle weakness. However, gastrointestinal complications such as chronic intestinal pseudo-obstruction (IPO), pancreatitis, gastroparesis and hepatopathy are also common. In this report we describe a young patient with gastrointestinal complication of MELAS which led to superior mesenteric artery syndrome (SMAS). It is rare but not surprising combination and should be considered in cases with significant weight loss and resistance to symptomatic treatment. The optimal energy support is the main pillar of the treatment.
    Learning points: Gastrointestinal complications of MELAS such as chronic intestinal pseudo-obstruction, pancreatitis and gastroparesis can lead to undernutrition.Superior mesenteric artery syndrome is a rare condition but should be considered in cases with significant weight loss and resistance to symptomatic treatment.Optimal caloric intake and energy support can improve the condition of patients with MELAS.
    Language English
    Publishing date 2024-01-22
    Publishing country Italy
    Document type Journal Article
    ISSN 2284-2594
    ISSN (online) 2284-2594
    DOI 10.12890/2024_004268
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  9. Article: Predictors of Outcome after Direct Aspiration of Basilar Artery Occlusion.

    Mako, Miroslav / Krastev, Georgi / Nosáľ, Vladimír / Haring, Jozef / Jakubcová, Denisa / Daniš, Martin / Klepanec, Andrej / Haršány, Ján / Sivák, Štefan / Kurča, Egon

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2024-03-09
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061576
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  10. Article: Traffic safety in the U.S.: re-examining major opportunities.

    Sivak, Michael / Luoma, Juha / Flannagan, Michael J / Bingham, C Raymond / Eby, David W / Shope, Jean T

    Journal of safety research

    2007  Volume 38, Issue 3, Page(s) 337–355

    Abstract: Introduction: This article examines five major road-safety risk factors: exceeding posted speed limits, not using safety belts, driving while intoxicated, nighttime driving, and young drivers.: Method: The importance of each of these factors is ... ...

    Abstract Introduction: This article examines five major road-safety risk factors: exceeding posted speed limits, not using safety belts, driving while intoxicated, nighttime driving, and young drivers.
    Method: The importance of each of these factors is documented, known effective countermeasures (both policy and technology based) are discussed, and impediments to the implementation of these countermeasures in the United States are examined.
    Results: Based on current understanding of the five major risk factors, and of the available countermeasures, there appear to be a variety of opportunities to make substantial gains in road safety using existing knowledge. The limited implementation of a variety of known countermeasures therefore appears to be inconsistent with high-level, strategic goals to improve road safety. Consequently, a recommendation is made to comprehensively re-examine the balance between the countermeasures discussed in this article and economic, mobility, and privacy concerns. IMPACT ON PUBLIC SAFETY: Such a re-examination is likely to result in broad support for these countermeasures, with a consequent major improvement in road safety.
    MeSH term(s) Accidents, Traffic/prevention & control ; Automobile Driving/legislation & jurisprudence ; Humans ; Safety Management/legislation & jurisprudence ; United States
    Language English
    Publishing date 2007
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2015321-1
    ISSN 1879-1247 ; 0022-4375
    ISSN (online) 1879-1247
    ISSN 0022-4375
    DOI 10.1016/j.jsr.2007.05.003
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