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  1. Article ; Online: Ultrasound in COVID-19: a timeline of ultrasound findings in relation to CT.

    Fiala, M J

    Clinical radiology

    2020  Volume 75, Issue 7, Page(s) 553–554

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/diagnostic imaging ; Coronavirus Infections/physiopathology ; Humans ; Lung/diagnostic imaging ; Lung/physiopathology ; Pandemics ; Pneumonia, Viral/diagnostic imaging ; Pneumonia, Viral/physiopathology ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods ; Ultrasonography/methods
    Keywords covid19
    Language English
    Publishing date 2020-04-18
    Publishing country England
    Document type Letter ; Review
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2020.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.201: Show issues Location:
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  2. Article ; Online: The Mediating Effects of Education and Occupational Complexity Between Race and Longitudinal Change in Late Life Cognition in ACTIVE.

    Owens, Joshua H / Fiala, Jacob / Jones, Richard N / Marsiske, Michael

    Research on aging

    2024  , Page(s) 1640275241248825

    Abstract: This study examined educational and occupational inequality as two aspects of social determinants of health that might mediate the longitudinal relationship between racialization and late life cognitive level and change. Participants were 2371 ... ...

    Abstract This study examined educational and occupational inequality as two aspects of social determinants of health that might mediate the longitudinal relationship between racialization and late life cognitive level and change. Participants were 2371 individuals racialized as Black and White from the ACTIVE study who provided occupational data. Data were analyzed from baseline and five assessments over 10-years using structural equation modeling. Black/White race served as the predictor, occupational complexity (OC) and years of education as mediators, and cognitive (memory, reasoning, and speed of processing) intercept, linear slope, and quadratic slope as the dependent variables. Black/White race showed significant indirect associations through education and OC on level of performance in cognition, linear change in reasoning and memory, and quadratic change in reasoning. Education and OC accounted for 11-16% of the association between race and cognitive level and represent modifiable social determinants of health that are associated with disparities in cognitive aging.
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424452-7
    ISSN 1552-7573 ; 0164-0275
    ISSN (online) 1552-7573
    ISSN 0164-0275
    DOI 10.1177/01640275241248825
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Ultrasound in COVID-19

    Fiala, M.J.

    Clinical Radiology

    a timeline of ultrasound findings in relation to CT

    2020  Volume 75, Issue 7, Page(s) 553–554

    Keywords Radiology Nuclear Medicine and imaging ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 391227-9
    ISSN 1365-229X ; 0009-9260
    ISSN (online) 1365-229X
    ISSN 0009-9260
    DOI 10.1016/j.crad.2020.04.003
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Neuromodulation's Role in Functional Restoration in Paraplegic and Quadriplegic Patients.

    Abd-Elsayed, Alaa / Robinson, Christopher L / Shehata, Peter / Koh, Yerin / Patel, Milan / Fiala, Kenneth J

    Biomedicines

    2024  Volume 12, Issue 4

    Abstract: Neuromodulation is an alternative, minimally invasive treatment option that, at times, is used as a last resort for chronic pain conditions that are often refractory to other treatment modalities. Moreover, it offers promising prospects for individuals ... ...

    Abstract Neuromodulation is an alternative, minimally invasive treatment option that, at times, is used as a last resort for chronic pain conditions that are often refractory to other treatment modalities. Moreover, it offers promising prospects for individuals grappling with the formidable challenges posed by paraplegia and quadriplegia resulting from spinal cord injuries. This review article provides a comprehensive assessment of current treatment modalities specifically tailored for paraplegic and quadriplegic patients. We aim to evaluate the existing surgical and non-surgical interventions while delving into the role of neuromodulation in the restoration of function for individuals afflicted with these debilitating conditions. Additionally, we review the efficacy, limitations, and comparative outcomes of diverse treatment strategies available for the management of paraplegia and quadriplegia. Emphasizing the critical need for effective interventions beyond the initial 24 h surgical window, we elucidate the challenges associated with conventional therapies and their limited success in achieving comprehensive functional restoration. Central to this review is an in-depth exploration of neuromodulation's transformative potential in ameliorating the deficits caused by spinal cord injuries. With a particular focus on spinal cord stimulation (SCS), we analyze and compare the outcomes of neuromodulation modalities and traditional treatment regimens, shedding light on the promising strides made in fostering sensory perception, motor function, and patient satisfaction.
    Language English
    Publishing date 2024-03-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines12040720
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Cooled Radiofrequency Ablation for Intercostal Neuralgia.

    Fiala, Kenneth J / Martens, Joshua M / Keith, Mitchell K / Ghouse, Adam / Abd-Elsayed, Alaa

    The Ochsner journal

    2023  Volume 23, Issue 2, Page(s) 159–163

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-05-02
    Publishing country United States
    Document type Case Reports
    ISSN 1524-5012
    ISSN 1524-5012
    DOI 10.31486/toj.22.0087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Pulsed Radiofrequency for the Treatment of Trigeminal Neuralgia.

    Abd-Elsayed, Alaa / Martens, Joshua M / Fiala, Kenneth J / Izuogu, Angelica

    Current pain and headache reports

    2022  

    Abstract: Purpose of review: Trigeminal neuralgia is a sudden, unilateral, stabbing pain in the distribution of one or more branches of the fifth cranial nerve, with an overall prevalence ranging between 0.03 and 0.3%. While conservative treatments may offer ... ...

    Abstract Purpose of review: Trigeminal neuralgia is a sudden, unilateral, stabbing pain in the distribution of one or more branches of the fifth cranial nerve, with an overall prevalence ranging between 0.03 and 0.3%. While conservative treatments may offer temporary relief, many patients experience chronic headaches associated with their neuralgia. Invasive treatments are available for patients with intractable neuralgia; however, they may cause permanent tissue damage and often do not provide relief. This article examines pulsed radiofrequency (PRF) ablation (RFA) of the trigeminal nerve as a minimally invasive procedure that offers a promising alternative to invasive procedures for relief of trigeminal neuralgia while minimizing tissue damage.
    Recent findings: Efficacy of PRF and RFA in treating trigeminal neuralgia has been studied before, but literature lacks large size studies. The results of this retrospective study indicate that PRF can be used as a safe and effective treatment for patients suffering from trigeminal neuralgia that is refractory to conservative measures.
    Language English
    Publishing date 2022-11-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2055062-5
    ISSN 1534-3081 ; 1531-3433
    ISSN (online) 1534-3081
    ISSN 1531-3433
    DOI 10.1007/s11916-022-01092-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5477: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: Temporary Peripheral Nerve Stimulation as Treatment for Chronic Pain.

    Abd-Elsayed, Alaa / Keith, Mitchell K / Cao, Nancy N / Fiala, Kenneth J / Martens, Joshua M

    Pain and therapy

    2023  Volume 12, Issue 6, Page(s) 1415–1426

    Abstract: ... The improvement in pain scores between pre-op and post-op was statistically significant (M = 2.17, SD = 2.82, SEM ...

    Abstract Introduction: Chronic pain is a growing problem across the world, and in the midst of an opioid epidemic, it is imperative that alternative treatment measures are identified to help alleviate the pain experienced by these patients. Chronic pain greatly affects ones quality of life and many patients do not experience adequate relief with conventional treatment measures. The purpose of this retrospective analysis is to assess the efficacy of peripheral nerve stimulation (PNS) therapy in adult patients suffering from chronic pain refractory to conventional treatment measures who underwent therapy on various anatomical locations.
    Methods: This retrospective analysis consisted of data collected from electronic health records for n = 89 patients who underwent PNS therapy. Data collected relates to patient age, sex, weight, height, body mass index (BMI), diagnosis, targeted nerves, follow-up encounters, pain scores from before and after PNS therapy, and duration of improvement. Statistical analysis used SPSS software, version 26 (IBM), using a paired t test to assess significance between pre and post PNS therapy pain scores. P values were significant if found to be ≤ 0.05. Further analysis assessed the correlation between age and BMI with visual analog scale (VAS) pain improvement and subjective percentage pain relief.
    Results: The mean pre-operative (pre-op) pain score before PNS therapy was 6.36 (standard deviation (SD) = 2.18, SEM = 0.23) and the mean post-operative (post-op) pain score after PNS therapy was 4.19 (SD = 2.70, SEM = 0.29). The mean patient-reported percent improvement in pain following PNS therapy was 49.04% (SD = 34.79). The improvement in pain scores between pre-op and post-op was statistically significant (M = 2.17, SD = 2.82, SEM = 0.30, t(88) = 7.26, p < .001), 95% confidence interval (CI) [1.57, 2.76]. The mean duration of improvement for patients was 123 days after therapy initiation (min = 6, max = 683, SD = 126).
    Conclusions: This study demonstrated the potential role for PNS therapy in improving patient-reported pain levels for various neuropathies, targeting various nerves. With PNS therapy's use as a chronic pain treatment and available research being limited, further study needs to be done on the efficacy of PNS therapy for pain management and complications associated with PNS device placements at various locations.
    Language English
    Publishing date 2023-09-22
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2701614-6
    ISSN 2193-651X ; 2193-8237
    ISSN (online) 2193-651X
    ISSN 2193-8237
    DOI 10.1007/s40122-023-00557-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Dynamic frailty risk assessment among older adults with multiple myeloma: A population-based cohort study.

    Mian, Hira / Wildes, Tanya M / Vij, Ravi / Pianko, Matthew J / Major, Ajay / Fiala, Mark A

    Blood cancer journal

    2023  Volume 13, Issue 1, Page(s) 76

    Abstract: Multiple myeloma (MM) is a cancer of older adults and those who are more frail are at high risk of poor outcomes. Current tools for identifying and categorizing frail patients are often static and measured only at the time of diagnosis. The concept of ... ...

    Abstract Multiple myeloma (MM) is a cancer of older adults and those who are more frail are at high risk of poor outcomes. Current tools for identifying and categorizing frail patients are often static and measured only at the time of diagnosis. The concept of dynamic frailty (i.e. frailty changing over time) is largely unexplored in MM. In our study, adults with newly-diagnosed MM who received novel drugs between the years 2007-2014 were identified in the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked databases. Using a previously published cumulative deficit approach, a frailty index score was calculated at diagnosis and each landmark interval (1-yr, 2-yr, 3-yr post diagnosis). The association of frailty with overall survival (OS) both at baseline and at each landmark interval as well as factors associated with worsening frailty status over time were evaluated. Overall, 4617 patients were included. At baseline, 39% of the patients were categorized as moderately frail or severely frail. Among those who had 3 years of follow-up, frailty categorization changed post diagnosis in 93% of the cohort (78% improved and 72% deteriorated at least at one time point during the follow up period). In a landmark analysis, the predictive ability of frailty at the time of diagnosis decreased over time for OS (Harrell's C Statistic 0.65 at diagnosis, 0.63 at 1-yr, 0.62 at 2-yr, and 0.60 at 3-yr) and was inferior compared to current frailty status at each landmark interval. Our study is one of the first to demonstrate the dynamic nature of frailty among older adults with MM. Frailty may improve or deteriorate over time. Current frailty status is a better predictor of outcomes than frailty status at time of diagnosis, indicating the need for re-measurement in this high-risk patient population.
    MeSH term(s) Humans ; Aged ; United States/epidemiology ; Frailty/diagnosis ; Frailty/epidemiology ; Multiple Myeloma/diagnosis ; Multiple Myeloma/epidemiology ; Cohort Studies ; Frail Elderly ; Geriatric Assessment/methods ; Medicare ; Risk Assessment
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 2600560-8
    ISSN 2044-5385 ; 2044-5385
    ISSN (online) 2044-5385
    ISSN 2044-5385
    DOI 10.1038/s41408-023-00843-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Increasing awareness of sleep disorders in a safety net clinic: the role of volunteer medical students-a feasibility program.

    Kukulka, Justyna / Nutakki, Aparna / McCullough, Lindsay M / Khaled, Dany / Hendel, Emily / Fiala, Justin / Attarian, Hrayr

    Sleep & breathing = Schlaf & Atmung

    2024  

    Language English
    Publishing date 2024-03-19
    Publishing country Germany
    Document type Letter
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-024-03023-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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