Article ; Online: Inhalative as well as Intravenous Administration of H
International journal of molecular sciences
2022 Volume 23, Issue 10
Abstract: ... Hydrogen sulfide (H: Methods: Ischemia-reperfusion injury was induced in rats by a temporary increase ... in intraocular pressure (1 h). H: Results: Both inhalative and intravenously delivered H: Conclusion ... and inflammation. Both inhalative H ...
Abstract | Background: Neuronal ischemia-reperfusion injury (IRI), such as it can occur in glaucoma or strokes, is associated with neuronal cell death and irreversible loss of function of the affected tissue. Hydrogen sulfide (H Methods: Ischemia-reperfusion injury was induced in rats by a temporary increase in intraocular pressure (1 h). H Results: Both inhalative and intravenously delivered H Conclusion: Hydrogen sulfide acts, at least in part, via the mitogen-activated protein kinase (MAPK) ERK1/2 to reduce apoptosis and inflammation. Both inhalative H |
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MeSH term(s) | Administration, Intravenous ; Animals ; Hydrogen Sulfide/metabolism ; Hydrogen Sulfide/pharmacology ; Hydrogen Sulfide/therapeutic use ; Ischemia/metabolism ; Neuroprotection ; Rats ; Rats, Sprague-Dawley ; Reperfusion Injury/metabolism ; Retina/metabolism ; Vascular Endothelial Growth Factor A/metabolism |
Chemical Substances | Vascular Endothelial Growth Factor A ; Hydrogen Sulfide (YY9FVM7NSN) |
Language | English |
Publishing date | 2022-05-15 |
Publishing country | Switzerland |
Document type | Journal Article |
ZDB-ID | 2019364-6 |
ISSN | 1422-0067 ; 1422-0067 ; 1661-6596 |
ISSN (online) | 1422-0067 |
ISSN | 1422-0067 ; 1661-6596 |
DOI | 10.3390/ijms23105519 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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