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Article ; Online: Applications of Stretching Technique and Time Window Effects on Ultrasonic Velocity Monitoring in Concrete

Bibo Zhong / Jinying Zhu

Applied Sciences, Vol 12, Iss 14, p

2022 Volume 7130

Abstract: Coda wave interferometry (CWI) has been used to measure the relative wave-velocity change ( ... d V / V ... ) caused by small changes in materials. This study uses the stretching processing technique which has been used for CWI analysis ... ...

Abstract	Coda wave interferometry (CWI) has been used to measure the relative wave-velocity change ( <semantics> d V / V </semantics> ) caused by small changes in materials. This study uses the stretching processing technique which has been used for CWI analysis to investigate velocity changes of direct longitudinal (P) wave, direct shear (S) wave, and coda wave in concrete by choosing different time windows of ultrasonic signals. It is found that the obtained wave-velocity change depends on the time window position, because the relative contribution of P wave and S wave is different in each signal window. This paper presents three experimental scenarios of velocity change in concrete: early-age hydration, temperature change, and uniaxial loading. In early-age concrete, the S wave has a larger relative velocity change than the P wave, which is consistent with the microstructure development due to the hydration process. Temperature change causes a larger <semantics> d V / V </semantics> on the P wave than on the S wave, and the difference between P and S wave-velocity changes may be used to determine nonlinear elastic constants of materials. In the uniaxial loading experiment, analysis of the direct P wave can distinguish the acoustoelastic effects in the stress direction and the non-stress direction, which may potentially be used for stress evaluation in prestressed structures. However, the coda wave does not show this directional property to stress due to multiple scattering in the medium.
Keywords	stretching technique ; coda wave interferometry (CWI) ; hydration ; temperature ; uniaxial loading ; nondestructive evaluation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	535
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Thermo-acoustoelastic effect of Rayleigh wave: Theory and experimental verification.

Zeng, Shengyang / Zhu, Jinying / Zhong, Bibo / Li, Xiongbing

Ultrasonics

2023 Volume 131, Page(s) 106948

Abstract: Previous studies showed that the thermally-induced ultrasonic bulk wave velocity change could be used to measure acoustoelastic coefficients and third-order elastic constants of elastic materials. This method is naturally immune from the ambient ... ...

Abstract	Previous studies showed that the thermally-induced ultrasonic bulk wave velocity change could be used to measure acoustoelastic coefficients and third-order elastic constants of elastic materials. This method is naturally immune from the ambient temperature effect and has improved sensitivity and a simpler test setup than the conventional acoustoelastic test. However, Rayleigh wave is preferred for thick components or structures with only one accessible surface. In this work, the thermo-hyperelastic constitutive equation, along with acoustoelastic theory, is used to derive the expression of the thermo-acoustoelastic coefficient (TAEC) of Rayleigh wave. The numerical relationship between the TAEC of Rayleigh wave and Murnaghan constants (l, m and n) are given for common metals. The TAEC expressions for Rayleigh wave and shear wave are similar, and both are dominated by the constant m. The TAEC of Rayleigh wave was measured on an aluminum 6061 specimen using the thermal modulation experiment in a temperature range of 22 ∼35 °C. The measured TAEC shows good agreement with the theoretical calculation. Then the third-order elastic constants were calculated based on TAECs of bulk waves and Rayleigh wave.
Language	English
Publishing date	2023-02-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	200839-7
ISSN	1874-9968 ; 0041-624X
ISSN (online)	1874-9968
ISSN	0041-624X
DOI	10.1016/j.ultras.2023.106948
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Article ; Online: Host Recovery from Respiratory Viral Infection.

Wei, Xiaoqin / Narasimhan, Harish / Zhu, Bibo / Sun, Jie

Annual review of immunology

2023 Volume 41, Page(s) 277–300

Abstract: Emerging and re-emerging respiratory viral infections pose a tremendous threat to human society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the respiratory tract, the host initiates coordinated innate and adaptive immune ... ...

Abstract	Emerging and re-emerging respiratory viral infections pose a tremendous threat to human society, as exemplified by the ongoing COVID-19 pandemic. Upon viral invasion of the respiratory tract, the host initiates coordinated innate and adaptive immune responses to defend against the virus and to promote repair of the damaged tissue. However, dysregulated host immunity can also cause acute morbidity, hamper lung regeneration, and/or lead to chronic tissue sequelae. Here, we review our current knowledge of the immune mechanisms regulating antiviral protection, host pathogenesis, inflammation resolution, and lung regeneration following respiratory viral infections, mainly using influenza virus and SARS-CoV-2 infections as examples. We hope that this review sheds light on future research directions to elucidate the cellular and molecular cross talk regulating host recovery and to pave the way to the development of pro-repair therapeutics to augment lung regeneration following viral injury.
MeSH term(s)	Humans ; Animals ; COVID-19 ; Immunity, Innate ; Pandemics ; SARS-CoV-2 ; Inflammation/pathology
Language	English
Publishing date	2023-01-30
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, N.I.H., Extramural
ZDB-ID	604953-9
ISSN	1545-3278 ; 0732-0582
ISSN (online)	1545-3278
ISSN	0732-0582
DOI	10.1146/annurev-immunol-101921-040450
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Article: Unlocking phenotypic plasticity provides novel insights for immunity and personalized therapy in lung adenocarcinoma.

Wang, Feng / Du, Hongjuan / Li, Bibo / Luo, Zhibin / Zhu, Lei

Frontiers in genetics

2022 Volume 13, Page(s) 941567

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2022-09-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2022.941567
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Article ; Online: Synergistic effects of core-shell structured piperazine pyrophosphate microcapsules on fire safety and mechanical property in styrenic thermoplastic elastomer.

Zhu, Min / Jia, Pengfei / Yang, Guisheng / Song, Lei / Hu, Yuan / Wang, Bibo

Journal of colloid and interface science

2023 Volume 653, Issue Pt B, Page(s) 1112–1122

Abstract: In this study, core-shell structured piperazine pyrophosphate (PAPP) is designed to enhance the fire safety and mechanical property of styrenic thermoplastic elastomer (TPE) composites. The PAPP is microencapsulated with carbon nanotube modified melamine- ...

Abstract	In this study, core-shell structured piperazine pyrophosphate (PAPP) is designed to enhance the fire safety and mechanical property of styrenic thermoplastic elastomer (TPE) composites. The PAPP is microencapsulated with carbon nanotube modified melamine-formaldehyde resin to prepare core-shell structured flame retardants (MT@PAPP). Due to the excellent compatibility between the MT@PAPP and TPE matrix, the mechanical property of TPE/MT@PAPP is improved. Compared with TPE, the peak heat release rate and peak smoke production rate of TPE/MT@PAPP are decreased by 78.5% and 60.0%, respectively. Thus, the core-shell structured piperazine pyrophosphate microcapsule strategy provides an excellent approach to obtain high-performance TPE composites.
Language	English
Publishing date	2023-09-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	241597-5
ISSN	1095-7103 ; 0021-9797
ISSN (online)	1095-7103
ISSN	0021-9797
DOI	10.1016/j.jcis.2023.09.147
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Article ; Online: Japanese encephalitis virus NS1 and NS1' protein disrupts the blood-brain barrier through macrophage migration inhibitory factor-mediated autophagy.

Zhang, Luping / Nan, Xiaowei / Zhou, Dengyuan / Wang, Xugang / Zhu, Shuo / Li, Qiuyan / Jia, Fan / Zhu, Bibo / Si, Youhui / Cao, Shengbo / Ye, Jing

Journal of virology

2024 , Page(s) e0011624

Abstract: Flaviviruses in the Japanese encephalitis virus (JEV) serogroup, such as JEV, West Nile virus, and St. Louis encephalitis virus, can cause severe neurological diseases. The nonstructural protein 1 (NS1) is a multifunctional protein of flavivirus that can ...

Abstract	Flaviviruses in the Japanese encephalitis virus (JEV) serogroup, such as JEV, West Nile virus, and St. Louis encephalitis virus, can cause severe neurological diseases. The nonstructural protein 1 (NS1) is a multifunctional protein of flavivirus that can be secreted by infected cells and circulate in the host bloodstream. NS1' is an additional form of NS1 protein with 52 amino acids extension at its carboxy-terminal and is produced exclusively by flaviviruses in the JEV serogroup. In this study, we demonstrated that the secreted form of both NS1 and NS1' can disrupt the blood-brain barrier (BBB) of mice, with NS1' exhibiting a stronger effect. Using the
Language	English
Publishing date	2024-04-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	80174-4
ISSN	1098-5514 ; 0022-538X
ISSN (online)	1098-5514
ISSN	0022-538X
DOI	10.1128/jvi.00116-24
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Article ; Online: Whether full-length IL-38 acts as a promoter or inhibitor in activating rheumatoid arthritis fibroblast-like synoviocytes depends on IL-1β.

Ding, Yudan / Shao, Ju / Liu, Cai / Li, Zhengtong / Zhang, Yuping / Jie, Ligang / Zhu, Xiaotong / Liang, Bibo / Yu, Qinghong / Wu, Jing

International journal of rheumatic diseases

2024 Volume 27, Issue 1, Page(s) e15020

Abstract: Aim: IL-38 is a recently discovered inflammatory factor that belongs to the IL-1 family and has full-length and truncated forms. Clinical findings demonstrated that serum IL-38 levels in people with infectious and autoimmune diseases are significantly ... ...

Abstract	Aim: IL-38 is a recently discovered inflammatory factor that belongs to the IL-1 family and has full-length and truncated forms. Clinical findings demonstrated that serum IL-38 levels in people with infectious and autoimmune diseases are significantly different from those in healthy people, but the form remains unclear. We are keenly interested in learning more about the regulatory role of full-length IL-38 in rheumatoid arthritis (RA), a classic autoimmune disease. Methods: RA-fibroblast-like synoviocytes (RA-FLS) were isolated from six RA patients and stimulated with full-length IL-38 to observe IL-6 and IL-8 secretion. Then, the migration and invasion functions of FLS were assessed. Next, the protein expressions of the MAPK, NF-κB, and JAK pathways were evaluated. In addition, we examined the effect of full-length IL-38 on FLS functions in the presence of IL-1β. The function of FLS affected by full-length IL-38 was also examined after blocking IL-1 and IL-36 receptors. Results: The functions of FLS were activated after the cells were stimulated with full-length IL-38. IL-6 and IL-8 levels increased with an increase in the full-length IL-38 concentration, and full-length IL-38 induced the acceleration of FLS migration and invasion functions. In addition, the levels of proteins in the MAPK signaling pathway increased after stimulation with full-length IL-38 and depended on its concentration. However, when the FLS were stimulated by IL-38 and IL-1β simultaneously, all experiments generated opposite results. Full-length IL-38 inhibited FLS function in the presence of IL-1β. IL-1R and IL-36R blockers terminated all effects of full-length IL-38 on RA-FLS. Conclusion: Full-length IL-38 activates FLS functions and acts as a promoter in RA, whereas it inhibits FLS functions and acts as an inhibitor of RA in the presence of IL-1β. The function of full-length IL-38 can be blocked by IL-1Ra and IL-36Ra.
MeSH term(s)	Humans ; Synoviocytes/metabolism ; Interleukin-6/metabolism ; Interleukin-8/metabolism ; Cells, Cultured ; Arthritis, Rheumatoid/genetics ; Arthritis, Rheumatoid/metabolism ; Fibroblasts/metabolism ; Interleukin-1 ; Synovial Membrane ; Interleukins/pharmacology
Chemical Substances	Interleukin-6 ; Interleukin-8 ; Interleukin-1 ; IL-38 protein, human ; Interleukins
Language	English
Publishing date	2024-01-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2426924-4
ISSN	1756-185X ; 1756-1841
ISSN (online)	1756-185X
ISSN	1756-1841
DOI	10.1111/1756-185X.15020
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Article ; Online: Prediction of Landslide Deformation Region Based on the Improved S-Growth Curve Model

Yuyang Li / Wen Nie / Qihang Li / Yang Zhu / Canming Yuan / Bibo Dai / Qiuping Kong

Applied Sciences, Vol 13, Iss 3555, p

2023 Volume 3555

Abstract: Quantitative research on and the prediction of a landslide deformation area is an important point to accurately and comprehensively understand the failure mechanism of landslides and the degree of slope failure. This study uses image processing ... ...

Abstract	Quantitative research on and the prediction of a landslide deformation area is an important point to accurately and comprehensively understand the failure mechanism of landslides and the degree of slope failure. This study uses image processing techniques to quantitatively identify the area and volume of deformation regions during rainfall-type landslide destabilization under multifactor conditions. The findings revealed that (1) an increase in rainfall intensity and slope angle, as well as the existence of slope crest, will accelerate the process of slope instability. In our study, when the rainfall intensity was 140 mm/h and the landslide volume reached 35.68%, the landslide failure was the most serious. (2) Slopes with high compaction of subsoil as well as those without perimeter pressure are relatively more damaged. (3) The higher the density of vegetation cover, the stronger the protection ability of the slope, and the higher the wind speed, the greater the failure to the slope. Furthermore, an improved S-growth curve model was proposed to predict landslide volumes in 16 sets of experiments. In detail, the proposed S-growth curve model predicted landslide volumes with an average absolute percentage error of 4.34–16.77%. Compared with the time series analysis moving-average method (average absolute percentage error of 6.39–68.89%), the S-growth curve model not only has higher prediction accuracy but also can describe the three stages of deformation region development from a physical perspective and can be applied to the volume during landslide change prediction.
Keywords	deformation area ; landslide volume ; type of space damage ; S-growth curve model ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	910
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Ferroptosis contributes to JEV-induced neuronal damage and neuroinflammation.

Zhu, Wenjing / Li, Qi / Yin, Yong / Chen, Huanchun / Si, Youhui / Zhu, Bibo / Cao, Shengbo / Zhao, Zikai / Ye, Jing

Virologica Sinica

2023 Volume 39, Issue 1, Page(s) 144–155

Abstract: Ferroptosis is a newly discovered prototype of programmed cell death (PCD) driven by iron-dependent phospholipid peroxidation accumulation, and it has been linked to numerous organ injuries and degenerative pathologies. Although studies have shown that ... ...

Abstract	Ferroptosis is a newly discovered prototype of programmed cell death (PCD) driven by iron-dependent phospholipid peroxidation accumulation, and it has been linked to numerous organ injuries and degenerative pathologies. Although studies have shown that a variety of cell death processes contribute to JEV-induced neuroinflammation and neuronal injury, there is currently limited research on the specific involvement of ferroptosis. In this study, we explored the neuronal ferroptosis induced by JEV infection in vitro and in vivo. Our results indicated that JEV infection induces neuronal ferroptosis through inhibiting the function of the antioxidant system mediated by glutathione (GSH)/glutathione peroxidase 4 (GPX4), as well as by promoting lipid peroxidation mediated by yes-associated protein 1 (YAP1)/long-chain acyl-CoA synthetase 4 (ACSL4). Further analyses revealed that JEV E and prM proteins function as agonists, inducing ferroptosis. Moreover, we found that treatment with a ferroptosis inhibitor in JEV-infected mice reduces the viral titers and inflammation in the mouse brains, ultimately improving the survival rate of infected mice. In conclusion, our study unveils a critical role of ferroptosis in the pathogenesis of JEV, providing new ideas for the prevention and treatment of viral encephalitis.
MeSH term(s)	Mice ; Animals ; Neuroinflammatory Diseases ; Ferroptosis ; Neurons/metabolism ; Encephalitis, Japanese ; Apoptosis
Language	English
Publishing date	2023-12-15
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1011219-4
ISSN	1995-820X ; 1000-3223 ; 1003-5125
ISSN (online)	1995-820X
ISSN	1000-3223 ; 1003-5125
DOI	10.1016/j.virs.2023.12.004
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Article: The Influencing Factors of Comprehensive Sexuality Education Capacity and Its Correlation with Subjective Social Status among Chinese Junior High School Students.

Zhu, Fan / Zhu, Guiyin / Jia, Bibo / Wang, Pei / Zhao, Tianjie / Ma, Yinghua / Dong, Bin

Children (Basel, Switzerland)

2022 Volume 9, Issue 8

Abstract: 1) Objective: Evidence suggests that comprehensive sexuality education (CSE) can protect and empower younger generations to advocate for their reproductive health and wellbeing. This survey aims to investigate the current status and influencing factors ... ...

Abstract	(1) Objective: Evidence suggests that comprehensive sexuality education (CSE) can protect and empower younger generations to advocate for their reproductive health and wellbeing. This survey aims to investigate the current status and influencing factors of CSE among Chinese junior high school students, and to evaluate its correlation with the learning experience of sex education and subjective social status (SSS) to provide evidence for the implementation of CSE in the future. (2) Methods: A total of 4109 participants aged 11 to 16 years were recruited using data from a cross-sectional survey among junior high school students in China in 2021. CSE knowledge, attitude, and skills were used to generate the CSE comprehensive capacity by a principal component analysis. One-way ANOVA was used to assess the different effects of school sex education and family sex education. Multiple linear regression was used to assess the association between CSE comprehensive capacity and SSS. (3) Results: The average score of CSE comprehensive capacity was 82.44 ± 8.60 (with a total score of 100 points) among participants. After the adjustment, subjective social status was positively related to CSE comprehensive capacity (B = 0.28, 95% CI: 0.20-0.36), and SSS (School) (beta = 0.62) had a higher impact on CSE comprehensive capacity compared to SSS (Family) (beta = -0.10). School sex education was associated with the CSE knowledge level with a larger magnitude compared to family sex education (mean deviation = -0.53,
Language	English
Publishing date	2022-08-10
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2732685-8
ISSN	2227-9067
ISSN	2227-9067
DOI	10.3390/children9081201
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