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  1. Book ; Online: Drug–Drug Interactions

    Kim, Dong Hyun / Lee, Sangkyu

    2021  

    Keywords Research & information: general ; Biology, life sciences ; tadalafil ; ticagrelor ; drug-drug interaction ; pharmacokinetics ; plasma concentration ; CYP3A4 ; Loxoprofen ; CYP3A ; Dexamethasone ; Ketoconazole ; CYP2D6 ; O-desmethyltramadol ; physiologically-based pharmacokinetics ; tramadol ; CYP2C9 ; potent inhibition ; in vitro ; in vivo ; drug interaction ; low permeability ; high plasma protein binding ; biflavonoid ; cytochrome P450 ; drug interactions ; selamariscina A ; uridine 5'-diphosphoglucuronosyl transferase ; tissue-specific ; systemic exposure ; P-glycoprotein (P-gp) ; organic anion transporting polypeptide 1A2 (OATP1A2) ; Rumex acetosa ; fexofenadine ; chronic kidney disease ; drug-drug interactions ; polypharmacy ; adverse drug reactions ; Lexicomp ; subset analysis ; signal detection algorithms ; spontaneous reporting systems ; mechanism-based inhibition ; competitive inhibition ; non-competitive inhibition ; substrate ; inhibitor ; cytochromes P450 ; OATP1B1 ; OATP1B3 ; tyrosine kinase inhibitors ; migraine ; lasmiditan ; gepants ; monoclonal antibodies ; CYP1A1 ; CYP1A2 ; expression ; metabolism ; regulation ; drug transporter ; ubiquitination ; ixazomib ; DDI ; computational prediction ; in silico ; QSAR ; drug metabolism ; ADME ; CYP ; metabolic DDI ; P450 ; 1A2 ; 2B6 ; 2C19 ; 2C8 ; 2C9 ; 2D6 ; 3A4
    Size 1 electronic resource (242 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel, Switzerland
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021291412
    ISBN 9783036520360 ; 3036520368
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Posterior Ischemic Optic Neuropathy Following Skin Booster Injection.

    Joo, Hye Jun / Kim, Dong Hyun

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society

    2024  

    Language English
    Publishing date 2024-04-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1189901-3
    ISSN 1536-5166 ; 1070-8022
    ISSN (online) 1536-5166
    ISSN 1070-8022
    DOI 10.1097/WNO.0000000000002138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Case of congenital fixed dilated pupils due to ACTA2 gene mutation - Multisystemic Smooth Muscle Dysfunction Syndrome.

    Song, Jae Ryong / Kim, Dong Hyun

    Korean journal of ophthalmology : KJO

    2024  

    Language English
    Publishing date 2024-04-08
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 639346-9
    ISSN 2092-9382 ; 1011-8942
    ISSN (online) 2092-9382
    ISSN 1011-8942
    DOI 10.3341/kjo.2023.0130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Interaction of drugs with gut microbiota modulators.

    Kim, Dong-Hyun

    Drug metabolism reviews

    2023  Volume 55, Issue 3, Page(s) 181–194

    Abstract: Orally administered drugs undergo four stages of absorption, distribution, metabolism, and excretion in the body. However, before being absorbed into the body, orally administered drugs contact with gut microbiota, which catalyze their metabolic ... ...

    Abstract Orally administered drugs undergo four stages of absorption, distribution, metabolism, and excretion in the body. However, before being absorbed into the body, orally administered drugs contact with gut microbiota, which catalyze their metabolic reactions such as reduction, hydroxylation (including deconjugation), dehydrogenation, acetylation, etc. Although these metabolic reactions typically inactivate drugs (ranitidine, digoxin, and amlodipine), some activate them (sulfasalazine). The composition and quantity of gut microbiota are variable across individuals and fluctuated by gut microbiota modulators such as diets, drugs (antibiotics), probiotics, prebiotics, pathogen infections, and stressors. Gut microbiota-involved metabolisms of drugs in the gastrointestinal tract are dependent on the composition and quantity of gut microbiota. Therefore, the bioavailability of orally administered drugs is significantly affected by gut microbiota modulators. This review describes gut microbiota modulator-drug interactions.
    MeSH term(s) Humans ; Gastrointestinal Microbiome/physiology ; Probiotics ; Prebiotics ; Gastrointestinal Tract/metabolism ; Anti-Bacterial Agents/pharmacology
    Chemical Substances Prebiotics ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-04-04
    Publishing country England
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 184967-0
    ISSN 1097-9883 ; 0360-2532 ; 0012-6594
    ISSN (online) 1097-9883
    ISSN 0360-2532 ; 0012-6594
    DOI 10.1080/03602532.2023.2197178
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Infliximab for Intractable Paradoxical Reaction in Culture-Negative Tuberculosis Meningitis.

    Kim, Dong Hyun / Yoon, Tae Kyun / Choi, Jae-Phil / Lee, Seung Hyun

    Journal of clinical neurology (Seoul, Korea)

    2024  Volume 20, Issue 2, Page(s) 226–228

    Language English
    Publishing date 2024-01-05
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2500489-X
    ISSN 2005-5013 ; 1738-6586
    ISSN (online) 2005-5013
    ISSN 1738-6586
    DOI 10.3988/jcn.2023.0290
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Left Atrium Volume Measured with Multislice Computed Tomography as a Prognostic Predictor for Atrial Fibrillation Catheter Ablation Outcomes.

    Park, Jae-Hong / Yang, Dong-Hyun / Kim, Ji-Hyun / Kim, Yoo-Ri

    Journal of clinical medicine

    2024  Volume 13, Issue 7

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-03-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13071859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nodular Cutaneous Amyloidosis on the Nose Confirmed Using Electron Microscopy: A Case Report.

    Choi, Go Woon / Kim, Dong Hyun

    Annals of dermatology

    2023  Volume 35, Issue Suppl 2, Page(s) S376–S377

    Language English
    Publishing date 2023-12-05
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 1012662-4
    ISSN 2005-3894 ; 1013-9087
    ISSN (online) 2005-3894
    ISSN 1013-9087
    DOI 10.5021/ad.22.075
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Bridging the Gap Between Trial Adverse Events and Real-World Data.

    Kim, Sang Hyuk / Lee, Hyun / Park, Dong Won

    Cancer research and treatment

    2024  

    Language English
    Publishing date 2024-01-10
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2133613-1
    ISSN 2005-9256 ; 1598-2998
    ISSN (online) 2005-9256
    ISSN 1598-2998
    DOI 10.4143/crt.2024.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Gastric ulcer bleeding due to huge gastric submucosal lipoma: A rare case.

    Seo, Ji Won / Yoo, Hyun Joo / Kim, Dong Jin

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-01-31
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.01.105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Combination of interventional oncology local therapies and immunotherapy for the treatment of hepatocellular carcinoma.

    Kim, Dong-Hyun

    Journal of liver cancer

    2022  Volume 22, Issue 2, Page(s) 93–102

    Abstract: Interventional oncology (IO) local therapies of hepatocellular carcinoma (HCC) can activate anti-cancer immunity and it is potentially leading to an anti-cancer immunity throughout the body. For the development of an effective HCC treatment regime, great ...

    Abstract Interventional oncology (IO) local therapies of hepatocellular carcinoma (HCC) can activate anti-cancer immunity and it is potentially leading to an anti-cancer immunity throughout the body. For the development of an effective HCC treatment regime, great emphasis has been dedicated to different IO local therapy mediated immune modulation and possible combinations with immune checkpoint inhibitor immunotherapy. In this review paper, we summarize the status of combination of IO local therapy and immunotherapy, as well as the prospective role of therapeutic carriers and locally administered immunotherapy in advanced HCC.
    Language English
    Publishing date 2022-04-22
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ISSN 2383-5001
    ISSN (online) 2383-5001
    DOI 10.17998/jlc.2022.03.28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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