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  1. Article ; Online: The clinical chemistry score (CCS) achieves the highest efficacy when assessed with the 99% sensitivity benchmark for myocardial infarction.

    Kavsak, Peter A / Worster, Andrew

    International journal of cardiology

    2024  Volume 403, Page(s) 131898

    MeSH term(s) Humans ; Chemistry, Clinical ; Benchmarking ; Myocardial Infarction/diagnosis ; Acute Coronary Syndrome ; Biomarkers ; Troponin T ; Sensitivity and Specificity
    Chemical Substances Biomarkers ; Troponin T
    Language English
    Publishing date 2024-02-21
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2024.131898
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Imprecision and Delta Criteria for a New ESC 0/2-Hour Algorithm.

    Kavsak, Peter A / Hulett, Matthew / Worster, Andrew

    Clinical chemistry

    2022  Volume 68, Issue 5, Page(s) 721–722

    MeSH term(s) Algorithms ; Biomarkers ; Humans ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2022-03-05
    Publishing country England
    Document type Research Support, Non-U.S. Gov't ; Letter
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1093/clinchem/hvac026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: In suspected nephrolithiasis, US did not differ from CT for high-risk diagnoses but reduced radiation exposure.

    Worster, Andrew

    Annals of internal medicine

    2015  Volume 162, Issue 2, Page(s) JC4

    MeSH term(s) Female ; Humans ; Male ; Nephrolithiasis/diagnostic imaging ; Tomography, X-Ray Computed ; Ultrasonography
    Language English
    Publishing date 2015-01-20
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/ACPJC-2015-162-2-004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: ACP Journal Club: baseline plus 1-hour high-sensitivity cardiac troponin T improved early rule-out and rule-in of acute MI.

    Worster, Andrew

    Annals of internal medicine

    2015  Volume 163, Issue 4, Page(s) JC12

    MeSH term(s) Female ; Humans ; Male ; Myocardial Infarction/diagnosis ; Troponin T/blood
    Chemical Substances Troponin T
    Language English
    Publishing date 2015-08-18
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/ACPJC-2015-163-4-012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: α-channel and calcium-channel blockers are ineffective as medical expulsive therapy for ureteral stones regardless of size and location.

    Worster, Andrew

    Evidence-based medicine

    2015  Volume 20, Issue 5, Page(s) 171

    MeSH term(s) Calcium Channel Blockers/therapeutic use ; Colic/drug therapy ; Female ; Humans ; Male ; Nifedipine/therapeutic use ; Sulfonamides/therapeutic use ; Ureteral Diseases/drug therapy ; Urological Agents/therapeutic use
    Chemical Substances Calcium Channel Blockers ; Sulfonamides ; Urological Agents ; Nifedipine (I9ZF7L6G2L)
    Language English
    Publishing date 2015-10
    Publishing country England
    Document type Comment ; Journal Article
    ZDB-ID 1324346-9
    ISSN 1473-6810 ; 1356-5524
    ISSN (online) 1473-6810
    ISSN 1356-5524
    DOI 10.1136/ebmed-2015-110244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Inclusion of patient-level emergency department characteristics to classify potentially redirectable visits to subacute care: a modified Delphi consensus study.

    Strum, Ryan P / Tavares, Walter / Worster, Andrew / Griffith, Lauren E / Costa, Andrew P

    CMAJ open

    2023  Volume 11, Issue 1, Page(s) E70–E76

    Abstract: Background: Most patients transported by Ontario paramedics to the emergency department have non-emergent conditions and may be more appropriately served by subacute community-based care centres. We sought to determine consensus on a set of patient ... ...

    Abstract Background: Most patients transported by Ontario paramedics to the emergency department have non-emergent conditions and may be more appropriately served by subacute community-based care centres. We sought to determine consensus on a set of patient characteristics that could be useful to classify retrospective emergency department visits that had a high probability of being primary care-like and potentially redirectable to a subacute care centre by paramedics.
    Methods: We conducted a modified Delphi study to assess expert consensus on characteristics of patients transported by paramedics to the emergency department from August to October 2021. An expert Delphi committee was constructed of emergency and family physicians in Ontario using purposive sampling. Experts rated whether each characteristic was useful to be included in a classification to identify potentially redirectable visits retrospectively, as well as characteristic details (e.g., upper and lower bounds). Consensus was considered 75% agreement.
    Results: Sixteen experts participated in the study; the experts were mostly male (75%) and evenly divided between emergency and family medicine. After 2 rounds, consensus was achieved on 8 of 9 characteristics (89%). Four characteristics were determined as useful to classify potentially redirectable emergency department visits: age (81%), triage acuity (100%), specialist consult in the emergency department (94%) and emergency department visit outcome (81%). Specifications of each characteristic were refined as follows: young and middle-aged adults with a non-emergent triage acuity, did not receive a specialist physician consult in the emergency department and discharged from the emergency department.
    Interpretation: Strong consensus was achieved to specify a classification system for potentially redirectable emergency department visits. These results will be combined with knowledge of which subacute care centres could conduct the main physician interventions to retrospectively identify emergency department visits that could have been suitable for paramedic redirection for further research.
    Study registration: ID ISRCTN22901977.
    MeSH term(s) Adult ; Middle Aged ; Humans ; Male ; Female ; Delphi Technique ; Retrospective Studies ; Subacute Care ; Emergency Service, Hospital ; Physicians, Family
    Language English
    Publishing date 2023-01-24
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20220062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: ED Chest Pain Rules: Follow Your HEART?

    Kohn, Michael A / Worster, Andrew

    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

    2019  Volume 26, Issue 2, Page(s) 261–262

    MeSH term(s) Chest Pain ; Heart ; Humans ; Prognosis
    Language English
    Publishing date 2019-01-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1329813-6
    ISSN 1553-2712 ; 1069-6563
    ISSN (online) 1553-2712
    ISSN 1069-6563
    DOI 10.1111/acem.13647
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High-sensitivity cardiac troponin and the importance of cutoffs in patients with prior coronary artery bypass grafting with suspected NSTEMI.

    Kavsak, Peter A / Mondoux, Shawn E / Ainsworth, Craig / Worster, Andrew

    International journal of cardiology

    2022  Volume 356, Page(s) 36–37

    MeSH term(s) Biomarkers ; Coronary Artery Bypass/adverse effects ; Humans ; Non-ST Elevated Myocardial Infarction/diagnosis ; Non-ST Elevated Myocardial Infarction/surgery ; Troponin I ; Troponin T
    Chemical Substances Biomarkers ; Troponin I ; Troponin T
    Language English
    Publishing date 2022-03-23
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2022.03.041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Correction to: Lessons from a systematic literature review of the effectiveness of recombinant factor VIIa in acquired haemophilia.

    Tiede, Andreas / Worster, Andrew

    Annals of hematology

    2018  Volume 97, Issue 12, Page(s) 2531

    Abstract: ... factor VIIa in acquired haemophilia, written by Andreas Tiede and Andrew Worster, was originally ...

    Abstract The article Lessons from a systematic literature review of the effectiveness of recombinant factor VIIa in acquired haemophilia, written by Andreas Tiede and Andrew Worster, was originally published electronically on the publisher's internet portal (currently SpringerLink) on 26 May 2018 without open access.
    Language English
    Publishing date 2018-09-28
    Publishing country Germany
    Document type Journal Article ; Published Erratum
    ZDB-ID 1064950-5
    ISSN 1432-0584 ; 0939-5555 ; 0945-8077
    ISSN (online) 1432-0584
    ISSN 0939-5555 ; 0945-8077
    DOI 10.1007/s00277-018-3504-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Emergency department interventions that could be conducted in subacute care settings for patients with nonemergent conditions transported by paramedics: a modified Delphi study.

    Strum, Ryan P / Tavares, Walter / Worster, Andrew / Griffith, Lauren E / Costa, Andrew P

    CMAJ open

    2022  Volume 10, Issue 1, Page(s) E1–E7

    Abstract: Background: As the number of patients with nonemergent conditions who are transported by paramedics continues to increase in Ontario, redirecting specific patients to subacute settings may be more beneficial and suitable for both patients and emergency ... ...

    Abstract Background: As the number of patients with nonemergent conditions who are transported by paramedics continues to increase in Ontario, redirecting specific patients to subacute settings may be more beneficial and suitable for both patients and emergency departments. We aimed to evaluate whether emergency department interventions conducted on patients with nonemergent conditions who are transported by paramedics could be conducted in subacute health centres.
    Methods: We conducted a RAND/UCLA modified Delphi study in Ontario between Oct. 13 and Dec. 19, 2020. We used purposive sampling to recruit practising emergency and primary care physicians for an expert panel. We abstracted interventions given to adult patients with nonemergent conditions (18 yr of age or older) who were transported by paramedics to an emergency department from the National Ambulatory Care Reporting System (NACRS) database (Jan. 1, 2014, to Mar. 31, 2018). Participants in the expert panel rated the suitability of the 150 most frequently recorded emergency department interventions from the NACRS database, for completion in subacute health care centres. We set consensus at 70% agreement.
    Results: We invited 25 physician experts, 21 of whom consented to participate; 20 physicians completed round 1, and 18 physicians completed both rounds. After 2 rounds, consensus was reached on 146 (97.3%) interventions; 103 interventions (68.7%) were suitable for subacute centres, 43 (28.7%) for only the emergency department and 4 (2.6%) did not receive consensus. For subacute centres, all 103 interventions were rated for urgent care centres; walk-in medical centres were applicable for 46 (30.6%) interventions and clinics led by nurse practitioners for 47 (31.3%) interventions.
    Interpretation: Most interventions provided to patients with nonemergent conditions transported by paramedics to emergency departments were identified as suitable for urgent care clinics, with one-third being suitable for either walk-in medical centres or clinics led by nurse practitioners. This study has potential to inform a patient classification model for paramedic-initiated redirection of patients from emergency departments, although further contextualization is required for this to be implemented in clinical practice.
    Study registration: ID ISRCTN22901977.
    MeSH term(s) Adult ; Allied Health Personnel/statistics & numerical data ; Attitude of Health Personnel ; Delphi Technique ; Emergencies/epidemiology ; Emergency Medical Services/methods ; Emergency Medical Services/organization & administration ; Emergency Service, Hospital/organization & administration ; Female ; Humans ; Male ; Ontario/epidemiology ; Patient Transfer/organization & administration ; Physicians/statistics & numerical data ; Subacute Care/methods ; Subacute Care/organization & administration ; Triage/methods
    Language English
    Publishing date 2022-01-11
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20210148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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