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  1. Article ; Online: Music Individualization Recommendation System Based on Big Data Analysis.

    Sun, Pengfei

    Computational intelligence and neuroscience

    2022  Volume 2022, Page(s) 7646000

    Abstract: This study discovers a certain complementary relationship between different algorithms after conducting a comprehensive and in-depth analysis of proposal algorithms. This study proposes a big data music individualization proposal method based on big data ...

    Abstract This study discovers a certain complementary relationship between different algorithms after conducting a comprehensive and in-depth analysis of proposal algorithms. This study proposes a big data music individualization proposal method based on big data analysis, which integrates user behaviour, behaviour context, user information, and music work information, based on traditional music proposal methods; improves the collaborative filtering proposal algorithm based on user behaviour; and calculates the semantic similarity between lyrics, as well as the song co-occurrence similarity based on the user's music download history. Because the lyrics represent the thoughts and feelings that the song wishes to convey to the listeners, the proposal module is completed, and the music proposal system is realized, by combining the two different similar information, using the improved algorithm and the Hadoop distributed framework. The music similarity and label similarity are combined to alleviate the problem of cold start and data sparseness, and a mixed similarity calculation formula is proposed to calculate the similarity between music. The accuracy similarity of the big data music proposal model proposed in this study is improved by about 20% through experimental comparison when compared with the collaborative filtering model and the hybrid model. It reflects the efficiency, scalability, and stability of the music proposal system as well as the ability to meet users' individual music needs.
    MeSH term(s) Algorithms ; Big Data ; Data Analysis ; Emotions ; Music
    Language English
    Publishing date 2022-07-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2388208-6
    ISSN 1687-5273 ; 1687-5273
    ISSN (online) 1687-5273
    ISSN 1687-5273
    DOI 10.1155/2022/7646000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Low-grade myofibroblastic sarcoma mimicking a benign neoplasm in the neck soft tissue.

    Li, Yingying / Dong, Pengfei / Sun, Jingyao / Sun, Xinlong / Wang, Yuliang

    Oral oncology

    2024  Volume 150, Page(s) 106722

    MeSH term(s) Humans ; Fibrosarcoma ; Soft Tissue Neoplasms/diagnosis
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Letter
    ZDB-ID 1120465-5
    ISSN 1879-0593 ; 0964-1955 ; 1368-8375
    ISSN (online) 1879-0593
    ISSN 0964-1955 ; 1368-8375
    DOI 10.1016/j.oraloncology.2024.106722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A noncovalent backbone planarization strategy increases the NIR-II extinction coefficients for gas/phototheranostic applications.

    Cheng, Peng / Chen, Shangyu / Li, Jiewei / Yang, Wan / Chen, Pengfei / Miao, Han / Shen, Qingming / Sun, Pengfei / Fan, Quli

    Chemical communications (Cambridge, England)

    2024  Volume 60, Issue 3, Page(s) 332–335

    Abstract: We propose a noncovalent backbone planarization strategy to fabricate a gas/phototheranostic nanocomposite (B-E-NO NPs) in the near-infrared-II (NIR-II, 1000-1700 nm) window by incorporating noncovalent conformational locks. B-E-NO NPs display a giant ... ...

    Abstract We propose a noncovalent backbone planarization strategy to fabricate a gas/phototheranostic nanocomposite (B-E-NO NPs) in the near-infrared-II (NIR-II, 1000-1700 nm) window by incorporating noncovalent conformational locks. B-E-NO NPs display a giant NIR-II extinction coefficient, realizing multimodal imaging-guided high-efficiency NIR-II photothermal therapy (
    Language English
    Publishing date 2024-01-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d3cc04885c
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Flying Target Detection Technology Based on GNSS Multipath Signals.

    Zhu, Pengfei / Zhu, Qinglin / Dong, Xiang / Sun, Mingchen

    Sensors (Basel, Switzerland)

    2024  Volume 24, Issue 5

    Abstract: In this study, a passive radar system that detects flying targets is developed in order to solve the problems associated with traditional flying target detection systems (i.e., their large size, high power consumption, complex systems, and poor ... ...

    Abstract In this study, a passive radar system that detects flying targets is developed in order to solve the problems associated with traditional flying target detection systems (i.e., their large size, high power consumption, complex systems, and poor battlefield survivability). On the basis of target detection, the system uses the multipath signal (which is usually eliminated as an error term in navigation and positioning), enhances it by supporting information, and utilizes the multi-source characteristics of ordinary omnidirectional global navigation satellite system (GNSS) signals. The results of a validation experiment showed that the system is able to locate a passenger airplane and obtain its flight trajectory using only one GNSS receiving antenna. The system is characterized by its light weight (less than 5 kg), low power consumption, simple system, good portability, low cost, and 24/7 and all-weather work. It can be installed in large quantities and has good prospects for development.
    Language English
    Publishing date 2024-03-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s24051706
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Prognostic biomarker NEIL3 and its association with immune infiltration in renal clear cell carcinoma.

    Sun, Xiaomei / Liu, Pengfei

    Frontiers in oncology

    2023  Volume 13, Page(s) 1073941

    Abstract: Background: Kidney renal clear cell carcinoma (KIRC) is a malignant tumor with a high degree of immune infiltration. Identifying immune biomarkers is essential for the treatment of KIRC. Studies have identified the potential of NEIL3 to modulate the ... ...

    Abstract Background: Kidney renal clear cell carcinoma (KIRC) is a malignant tumor with a high degree of immune infiltration. Identifying immune biomarkers is essential for the treatment of KIRC. Studies have identified the potential of NEIL3 to modulate the immune microenvironment and promote tumor progression. However, the role of NEIL3 in KIRC remains uncertain. This study was to investigate the effect of NEIL3 on the prognosis and immune infiltration of patients with KIRC.
    Methods: TCGA and GEO databases were used to study the expression of NEIL3 in KIRC. Cox regression analysis was used to examine the relationship between the expression of NEIL3 and clinicopathological variables and survival. Furthermore, Gene Set Cancer Analysis (GSCA) was applied to study the impact of NEIL3 methylation on outcomes of KIRC. Through gene ontology (GO) and Gene set enrichment (GSEA) analysis, the biological processes and signal pathways related to NEIL3 expression were identified. In addition, immune infiltration analysis was conducted
    Results: NEIL3 was overexpressed in KIRC, and it was significantly related with histologic grade, pathologic stage, T stage, M stage, and vital status of KIRC patients (
    Conclusion: NEIL3 is a potential independent biomarker of KIRC, which is relevant to immune infiltration.
    Language English
    Publishing date 2023-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1073941
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comprehensive understanding of electron mobility and superior performance in sub-10 nm DG ML tetrahex-GeC

    Xu, Yuehua / Li, Daqing / Sun, He / Xu, Haowen / Li, Pengfei

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 5, Page(s) 4284–4297

    Abstract: In this study, we have investigated the electron mobility of monolayered (ML) tetrahex- ... ...

    Abstract In this study, we have investigated the electron mobility of monolayered (ML) tetrahex-GeC
    Language English
    Publishing date 2024-01-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05327j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The impact of modifiable health metrics on mortality for older adults with low cognitive function.

    Wang, Wei / Sun, Pengfei / Lv, Tingting / Li, Min

    Frontiers in public health

    2024  Volume 12, Page(s) 1304876

    Abstract: Objectives: Cognitive impairment has emerged as a major contributing factor to mortality for older adults. Identifying the strong modifiable health metrics against mortality is of high priority, especially in this high-risk population.: Methods: This ...

    Abstract Objectives: Cognitive impairment has emerged as a major contributing factor to mortality for older adults. Identifying the strong modifiable health metrics against mortality is of high priority, especially in this high-risk population.
    Methods: This population-based study used data of US adults aged≥60 years old from the National Health and Nutrition Examination Survey 2011-2014 cycles. De-identified data for participants who completed cognitive function test were extracted. Mortality data was obtained by linking to the 2019 public-use linked mortality file.
    Results: Participants with low global cognition had higher risk of all-cause mortality (HR = 1.46; 95%CI, 1.04-2.05). The highest prevalence of ideal level of health metrics was observed for sleep duration (54.36% vs. 62.37%), and the lowest was noted for blood pressure (12.06% vs. 21.25%) for participants with low and average to high global cognition, respectively. Ideal status of physical activity and diet quality were significantly associated with all-cause mortality among participants with low global cognition (HR = 0.48, 95%CI: 0.28-0.82; HR = 0.63, 95%CI: 0.43-0.95). The corresponding population-attributable fractions were 26.58 and 15.90%, respectively.
    Conclusion: Low cognitive function was associated with increased risk of all-cause death for older adults. Attainment of healthy metrics, especially sufficient physical activity, consuming healthy diet and being never smoked, provided strong protection against death risk.
    MeSH term(s) Humans ; Aged ; Middle Aged ; Nutrition Surveys ; Quality Indicators, Health Care ; Cognition ; Risk Factors ; Cognitive Dysfunction/epidemiology
    Language English
    Publishing date 2024-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2024.1304876
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: USP13 Cooperates with MARCH8 to Inhibit Antiviral Signaling by Targeting MAVS for Autophagic Degradation in Teleost.

    Wang, Pengfei / Sun, Yuena / Xu, Tianjun

    Journal of immunology (Baltimore, Md. : 1950)

    2024  Volume 212, Issue 5, Page(s) 801–812

    Abstract: Mitochondrial antiviral signaling protein (MAVS), as a central adapter protein in retinoic acid-inducible gene I-like receptor signaling, is indispensable for innate antiviral immunity. Yet, the molecular mechanisms modulating the stability of MAVS are ... ...

    Abstract Mitochondrial antiviral signaling protein (MAVS), as a central adapter protein in retinoic acid-inducible gene I-like receptor signaling, is indispensable for innate antiviral immunity. Yet, the molecular mechanisms modulating the stability of MAVS are not fully understood in low vertebrates. In this study, we report that the deubiquitinase ubiquitin-specific protease 13 (USP13) acts as a negative regulator of antiviral immunity by targeting MAVS for selective autophagic degradation in teleost fish. USP13 is induced by RNA virus or polyinosinic:polycytidylic acid stimulation and acts as a negative regulator to potentiate viral replication in fish cells. Mechanistically, USP13 functions as a scaffold to enhance the interaction between MAVS and the E3 ubiquitin ligase MARCH8, thus promoting MARCH8 to catalyze MAVS through K27-linked polyubiquitination for selective autophagic degradation. Taken together, to our knowledge, our study demonstrates a novel mechanism by which viruses evade host antiviral immunity via USP13 in fish and provides a new idea for mammalian innate antiviral immunity.
    MeSH term(s) Animals ; Signal Transduction ; Immunity, Innate ; Ubiquitination ; RNA Viruses ; Carrier Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Mammals/metabolism
    Chemical Substances Carrier Proteins ; Ubiquitin-Protein Ligases (EC 2.3.2.27)
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.2300493
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficacy of non-invasive brain stimulation for post-stroke dysphagia: a meta-analysis.

    Yao, Shan / Wang, Xuxia / Sun, Jie / Guo, Pengfei

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

    2024  Volume 24, Issue 2, Page(s) 433–442

    Abstract: Background: Given the potential harms of dysphagia after stroke, we noticed the possibility of non-invasive brain stimulation treatments in the management process.: Methods: The meta-analysis search for articles published before May 2023 in databases. ...

    Abstract Background: Given the potential harms of dysphagia after stroke, we noticed the possibility of non-invasive brain stimulation treatments in the management process.
    Methods: The meta-analysis search for articles published before May 2023 in databases. We used STATA 12.0 software to compute the standard mean difference (SMD) and 95% confidence intervals (CI).
    Results: The study showed a greater improvement in swallowing function in post-stroke dysphagia given transcranial direct current stimulation (tDCS) immediately after treatment, compared to those given sham tDCS (SMD = 2.99, 95% CI = 1.86-4.11). The study showed a greater improvement in swallowing function in post-stroke dysphagia given tDCS some days after treatment, compared to those given sham tDCS (SMD = 2.01, 95% CI = 0.87-3.16). The study showed a greater improvement in swallowing function in post-stroke dysphagia given repetitive transcranial magnetic stimulation (rTMS) immediately after treatment, compared to those given sham rTMS (SMD = 4.17, 95% CI = 3.11-5.23). The study showed a greater improvement in swallowing function in post-stroke dysphagia given rTMS some days after treatment, compared to those given sham rTMS (SMD = 1.77, 95% CI = 0.94-2.60).
    Conclusions: In conclusion, our study showed the beneficial effects of non-invasive brain stimulation on difficulty swallowing for stroke patients and speculated about the potential application of non-invasive brain stimulation on post-stroke dysphagia improvement.
    MeSH term(s) Humans ; Deglutition Disorders/etiology ; Deglutition Disorders/therapy ; Transcranial Direct Current Stimulation ; Stroke/complications ; Stroke/therapy ; Brain
    Language English
    Publishing date 2024-02-09
    Publishing country England
    Document type Meta-Analysis ; Journal Article
    ZDB-ID 2213105-X
    ISSN 1479-8301 ; 1346-3500
    ISSN (online) 1479-8301
    ISSN 1346-3500
    DOI 10.1111/psyg.13090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A thermoresponsive nanocomposite integrates NIR-II-absorbing small molecule with lonidamine for pyroptosis-promoted synergistic immunotherapy.

    Chen, Pengfei / Zhang, Chi / He, Liuliang / Li, Mingfei / Rong, Jie / Sun, Pengfei / Chen, Yingying / Li, Daifeng

    Journal of nanobiotechnology

    2024  Volume 22, Issue 1, Page(s) 163

    Abstract: Photothermal immunotherapy is regarded as the ideal cancer therapeutic modality to against malignant solid tumors; however, its therapeutic benefits are often modest and require improvement. In this study, a thermoresponsive nanoparticle (BTN@LND) ... ...

    Abstract Photothermal immunotherapy is regarded as the ideal cancer therapeutic modality to against malignant solid tumors; however, its therapeutic benefits are often modest and require improvement. In this study, a thermoresponsive nanoparticle (BTN@LND) composed of a photothermal agent (PTA) and pyroptosis inducer (lonidamine) were developed to enhance immunotherapy applications. Specifically, our "two-step" donor engineering strategy produced the strong NIR-II-absorbing organic small-molecule PTA (BTN) that exhibited high NIR-II photothermal performance (ε
    MeSH term(s) Humans ; Phototherapy ; Pyroptosis ; Nanoparticles ; Neoplasms/drug therapy ; Immunotherapy ; Cell Line, Tumor ; Indazoles
    Chemical Substances lonidamine (U78804BIDR) ; Indazoles
    Language English
    Publishing date 2024-04-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2100022-0
    ISSN 1477-3155 ; 1477-3155
    ISSN (online) 1477-3155
    ISSN 1477-3155
    DOI 10.1186/s12951-024-02424-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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