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Article ; Online: Pancreatic cyst prevalence and detection with photon counting CT compared with conventional energy integrating detector CT.

Dane, Bari / Kim, Jesi / Qian, Kun / Megibow, Alec

2024 Volume 175, Page(s) 111437

Abstract: Purpose: To calculate the prevalence of pancreatic cysts on photon counting CT (PCCT) and compare with that of 128-slice conventional energy-integrating detector CT (EIDCT).: Method: A retrospective single institution database search identified all ... ...

Abstract	Purpose: To calculate the prevalence of pancreatic cysts on photon counting CT (PCCT) and compare with that of 128-slice conventional energy-integrating detector CT (EIDCT). Method: A retrospective single institution database search identified all contrast-enhanced abdominal CT examinations performed at an outpatient facility that has both a PCCT and EIDCT between 4/11/2022 and 7/26/2022. The presence and size of pancreatic cysts were recorded. In patients with PCCT reported pancreatic cysts, prior CT imaging (EIDCT) was reviewed for reported pancreatic cysts. Fisher's exact test was used to compare the pancreatic cyst detection rate for PCCT and EIDCT. Wilcoxon rank sum test was used to compare cyst size and patient age. A p <.05 indicated statistical significance. Results: 2494 patients were included. Our pancreatic cyst detection rate was 4.9 % (49/1009) with PCCT and 3.0 % (44/1485) for EIDCT (p =.017). For CT angiograms, pancreatic cysts were detected in 6.6 % (21/319) with PCCT and 0.0 % (0/141) with EIDCT (p <.001). Pancreatic cyst detection rate was not statistically different for portal venous, enterography, renal mass, pancreas, 3-phase liver, or venogram protocols (all p >.05). Mean[SD] pancreatic cyst size was 13.7[9.7]mm for PCCT and 15.3[14.7] for EIDCT (p =.95). 55.1 % (27/49) of PCCT and 61.4 % (27/44) of EIDCT that described pancreatic cysts had prior contrast-enhanced EIDCTs. Of these, 40.7 % (11/27) of PCCT and 14.8 % (4/27) of EIDCT described pancreatic cysts were not previously reported (p =.027). Conclusions: Photon-counting CT afforded greater pancreatic cyst detection than conventional energy-integrating detector CT, particularly with CT angiograms.
Language	English
Publishing date	2024-03-20
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2024.111437
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Article ; Online: Proposal of an Abbreviated Noncontrast MR Enterography Protocol for Patients With Crohn Disease.

Dillman, Jonathan R / Anupindi, Sudha A / Dane, Bari

AJR. American journal of roentgenology

2023 Volume 222, Issue 2, Page(s) e2330422

Abstract: MR enterography (MRE) protocols used in patients with Crohn disease are burdened by long acquisition time, high cost, and suboptimal patient experience. For several indications, highly diagnostic MRE can be performed in five or fewer sequences, without ... ...

Abstract	MR enterography (MRE) protocols used in patients with Crohn disease are burdened by long acquisition time, high cost, and suboptimal patient experience. For several indications, highly diagnostic MRE can be performed in five or fewer sequences, without IV contrast material or antiperistaltic medication and with an examination room time of less than 12 minutes. As such, MRE could be more patient friendly, more frequently performed, and require fewer health care resources.
MeSH term(s)	Humans ; Crohn Disease/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Contrast Media
Chemical Substances	Contrast Media
Language	English
Publishing date	2023-12-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	82076-3
ISSN	1546-3141 ; 0361-803X ; 0092-5381
ISSN (online)	1546-3141
ISSN	0361-803X ; 0092-5381
DOI	10.2214/AJR.23.30422
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Article: Pulmonary Crohn's Disease Masquerading as Lymphoma.

Beaty, William / Katragadda, Anila / Condos, Rany / Dane, Bari / Sarkar, Suparna / Shaffer, Emily / Chang, Shannon

ACG case reports journal

2024 Volume 11, Issue 1, Page(s) e01247

Abstract: Although extraintestinal manifestations of inflammatory bowel disease (IBD) are common, pulmonary IBD is extremely rare. Owing to its nonspecific clinical, radiologic, and pathologic features, pulmonary IBD is difficult to diagnose and may mimic more ... ...

Abstract	Although extraintestinal manifestations of inflammatory bowel disease (IBD) are common, pulmonary IBD is extremely rare. Owing to its nonspecific clinical, radiologic, and pathologic features, pulmonary IBD is difficult to diagnose and may mimic more concerning disease processes. We present a rare case of a patient with known Crohn's disease whose initial presentation was highly suspicious for malignancy before further investigation revealed pulmonary IBD.
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Case Reports
ZDB-ID	2814825-3
ISSN	2326-3253
ISSN	2326-3253
DOI	10.14309/crj.0000000000001247
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Article ; Online: MRI of the ileal pouch.

Huang, Chenchan / Dane, Bari / Santillan, Cynthia / Ream, Justin

Abdominal radiology (New York)

2023 Volume 48, Issue 9, Page(s) 2944–2955

Abstract: Ileal pouch surgery is the surgical gold standard treatment for patients with ulcerative colitis (UC) and familial adenomatous polyposis (FAP). However, ileal pouch surgery is a technically challenging procedure and is associated with high morbidity. ... ...

Abstract	Ileal pouch surgery is the surgical gold standard treatment for patients with ulcerative colitis (UC) and familial adenomatous polyposis (FAP). However, ileal pouch surgery is a technically challenging procedure and is associated with high morbidity. Clinical presentations of pouch complications are often nonspecific but imaging can identify many of these complications and is essential in clinical management. This paper will focus on magnetic resonance imaging (MRI) of the ileal pouch, including recommended MRI protocol and approach to imaging interpretation with an emphasis on those ileal pouch complications particularly well evaluated with MRI.
MeSH term(s)	Humans ; Proctocolectomy, Restorative/methods ; Colonic Pouches/adverse effects ; Adenomatous Polyposis Coli/diagnostic imaging ; Adenomatous Polyposis Coli/surgery ; Adenomatous Polyposis Coli/etiology ; Colitis, Ulcerative/diagnostic imaging ; Colitis, Ulcerative/surgery ; Magnetic Resonance Imaging
Language	English
Publishing date	2023-02-05
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-023-03803-6
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Article ; Online: Rectal and perirectal CT findings in patients with monkeypox virus infection.

Ola, David / Dane, Bari / Shanbhogue, Krishna / Smereka, Paul

Abdominal radiology (New York)

2023 Volume 48, Issue 7, Page(s) 2284–2291

Abstract: Objective: To analyze the findings of proctitis in patients with laboratory-confirmed Mpox and correlate the patient clinical presentation and laboratory findings.: Methods: 21 patients with PCR-positive Mpox who obtained abdominopelvic CT were ... ...

Abstract	Objective: To analyze the findings of proctitis in patients with laboratory-confirmed Mpox and correlate the patient clinical presentation and laboratory findings. Methods: 21 patients with PCR-positive Mpox who obtained abdominopelvic CT were retrospectively identified by electronic medical record search. Three radiologists independently evaluated CT images, measuring rectal wall thickness (cm), degree of perirectal fat stranding on a 5-point Likert scale, and size of perirectal lymph nodes (cm, short axis). Mann-Whitney U-test (Wilcoxon rank sum test) was used to assess the association of rectal wall thickness and perirectal fat standing between patients with rectal symptoms and patients without rectal symptoms. Results: 20 of 21 patients presented with perirectal fat stranding, with mean Likert score of 3.0 ± 1.4, indicating moderate perirectal stranding. Mean transverse rectal wall thickness was 1.1 ± 0.5 cm (range 0.3-2.3 cm); it was thicker among patients with HIV (1.2 cm vs 0.7 cm; p = .019). Mean perirectal fat stranding was greater among patients presenting with HIV, and with rectal symptoms, though not significantly so. 17/21 (81%) patients had abnormal mesorectal lymph nodes by at least two of three readers, with mean short-axis measurement 1.0 ± 0.3 cm (range 0.5-1.6 cm). Multiple linear regression showed no significant correlation between rectal thickness and laboratory values or HIV status. Conclusion: Nearly all patients with Mpox who presented with additional symptoms warranting a CT demonstrated proctitis. Degree of proctitis varied greatly within the cohort, with greatest thickening among patients with HIV. Physicians should have a high suspicion for proctitis in patients with suspected Mpox.
MeSH term(s)	Humans ; Rectal Neoplasms/pathology ; Mpox (monkeypox) ; Retrospective Studies ; Monkeypox virus ; Proctitis/diagnostic imaging ; Tomography, X-Ray Computed ; HIV Infections
Language	English
Publishing date	2023-05-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-023-03933-x
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Article ; Online: Crohn's disease inflammation severity assessment with iodine density from photon counting CT enterography: comparison with endoscopic histopathology.

Dane, Bari / Qian, Kun / Soni, Ria / Megibow, Alec

Abdominal radiology (New York)

2023 Volume 49, Issue 1, Page(s) 271–278

Abstract: Purpose: To determine optimal iodine density thresholds for active inflammation in CD patients with PCCT enterography and determine if iodine density can be used to stratify CD activity severity.: Methods: A retrospective PACS search identified ... ...

Abstract	Purpose: To determine optimal iodine density thresholds for active inflammation in CD patients with PCCT enterography and determine if iodine density can be used to stratify CD activity severity. Methods: A retrospective PACS search identified patients with CD imaged with PCCT enterography from 4/11/2022 to 10/30/2022 and with clinical notes, endoscopic/surgical pathology and available source PCCT data for iodine density analysis. Two abdominal radiologists with expertise in CD each drew two region of interest measurements within the visibly most affected region of terminal or neoterminal ileum wall on commercially available system (SyngoVia). Radiologists were blinded to clinical information and pathologic findings. Disease activity and severity were recorded from the pathology report. Harvey-Bradshaw Index, medications, and laboratory values were recorded. Receiver operating characteristic (ROC) curves were utilized to determine the optimum iodine density threshold for active inflammation and mild versus moderate-to-severe inflammation. Intra- and inter-reader agreement was assessed by intra-class correlation coefficient (ICC). Results: 23 CD patients (15 females; mean [SD] age: 52 [17] years) imaged with PCCT enterography were included. 15/23 had active inflammation: 9/15 mild, 4/15 moderate, and 2/15 severe active inflammation. The optimal iodine density threshold for active inflammation was 2.7 mg/mL, with 97% sensitivity, 100% specificity, and 98% accuracy (AUC = 1.00). The optimal iodine density threshold for distinguishing mild from moderate-to-severe inflammation was 3.4 mg/mL, with 83% sensitivity, 89% specificity, and 87% accuracy (AUC = 0.85). Intra-reader reliability (R1/R2) ICC was 0.81/0.86. Inter-reader reliability ICC was 0.94. Conclusion: Iodine density from PCCT enterography can distinguish mild from moderate-to-severe active inflammation.
MeSH term(s)	Female ; Humans ; Middle Aged ; Crohn Disease/diagnostic imaging ; Crohn Disease/pathology ; Retrospective Studies ; Iodine ; Reproducibility of Results ; Tomography, X-Ray Computed/methods ; Inflammation/diagnostic imaging ; Inflammation/pathology
Chemical Substances	Iodine (9679TC07X4)
Language	English
Publishing date	2023-10-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-023-04060-3
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Article ; Online: Protocol optimization for abdominal imaging using photon-counting CT: a consensus of two academic institutions.

Schwartz, Fides R / Marin, Daniele / Lofino, Ludovica / Abadia, Andres / O'Donnell, Thomas / Dane, Bari

Abdominal radiology (New York)

2024

Abstract: Purpose: Photon-counting detector CT (PCD CT) is a promising technology for abdominal imaging due to its ability to provide high spatial and contrast resolution images with reduced patient radiation exposure. However, there is currently no consensus ... ...

Abstract	Purpose: Photon-counting detector CT (PCD CT) is a promising technology for abdominal imaging due to its ability to provide high spatial and contrast resolution images with reduced patient radiation exposure. However, there is currently no consensus regarding the optimal imaging protocols for PCD CT. This article aims to present the PCD CT abdominal imaging protocols used by two tertiary care academic centers in the United States. Methods: A review of PCD CT abdominal imaging protocols was conducted by two abdominal radiologists at different academic institutions. Protocols were compared in terms of acquisition parameters and reconstruction settings. Both imaging centers independently selected similar protocols for PCD CT abdominal imaging, using QuantumPlus mode. Results: There were some differences in the use of reconstruction kernels and iterative reconstruction levels, however the individual combination at each site resulted in similar image impressions. Overall, the imaging protocols used by both centers provide high-quality images with low radiation exposure. Conclusion: These findings provide valuable insights into the development of standardized protocols for PCD CT abdominal imaging, which can help to ensure consistent as well as high-quality imaging across different institutions and allow for future multicenter research collaborations.
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-024-04254-3
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Article ; Online: Feasibility of Abdominal Magnetic Resonance Imaging in Patients With Residual Concentrated Enteric Contrast After Fluoroscopic Abdominal Examination.

Dane, Bari / Hindman, Nicole

Journal of computer assisted tomography

2021 Volume 45, Issue 5, Page(s) 678–683

Abstract: Objective: This study aimed to evaluate the image quality, image artifacts, radiologist confidence, and ability to provide definitive diagnosis for all patients with magnetic resonance imaging (MRI) performed after an abdominal fluoroscopic examination ... ...

Abstract	Objective: This study aimed to evaluate the image quality, image artifacts, radiologist confidence, and ability to provide definitive diagnosis for all patients with magnetic resonance imaging (MRI) performed after an abdominal fluoroscopic examination and to determine the utility of MRI in this setting. Methods: Thirty-one MRI examinations performed a median of 2 days after fluoroscopic bowel evaluation (barium, n = 13; iodine, n = 18), 20 within 3 days of MRI, were retrospectively reviewed. The image quality, artifact emanating from bowel, inhomogeneity artifact, radiologist confidence, ability to render a definitive diagnosis, and identification of emergent or important findings for all MRI examinations were assessed. These same features were evaluated on 5 computed tomographies performed after fluoroscopy (before the MRI) in the same cohort. Results: All 31 MRI examinations performed after fluoroscopic studies with concentrated barium or iodine solutions were diagnostic for answering the clinical question according to radiologist and report review, regardless of magnet strength and type of fluoroscopic contrast ingested. Magnetic resonance imaging after fluoroscopy had excellent overall image quality (mean score, 4.74/5), minimal to no artifact emanating from bowel (mean, 4.63/5), minimal inhomogeneity artifact (mean, 4.38/5), and excellent diagnostic confidence (mean, 4.98/5). No additional imaging was necessary for diagnosis after MRI. Computed tomography after fluoroscopy had lower overall image quality, more image artifacts, and lower diagnostic confidence (P < 0.05). Conclusions: Magnetic resonance imaging is a useful tool for evaluating patients with retained concentrated enteric contrast from recent fluoroscopic examinations. In the absence of contraindication, MRI should be considered in the evaluation of urgent clinical problems in patients who recently underwent a fluoroscopic bowel evaluation.
MeSH term(s)	Abdomen/diagnostic imaging ; Artifacts ; Cohort Studies ; Contrast Media/pharmacokinetics ; Feasibility Studies ; Female ; Fluoroscopy ; Humans ; Image Interpretation, Computer-Assisted/methods ; Intestinal Diseases/diagnostic imaging ; Intestines/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Radiographic Image Enhancement/methods ; Retrospective Studies
Chemical Substances	Contrast Media
Language	English
Publishing date	2021-09-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	80392-3
ISSN	1532-3145 ; 0363-8715
ISSN (online)	1532-3145
ISSN	0363-8715
DOI	10.1097/RCT.0000000000001233
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Article: Current and Emerging Approaches to the Diagnosis and Treatment of Crohn's Disease Strictures.

Lee, Briton / Dane, Bari / Katz, Seymour

Gastroenterology & hepatology

2022 Volume 18, Issue 4, Page(s) 186–195

Abstract: The management and understanding of Crohn's disease (CD) continues to evolve quickly. Intestinal strictures were previously thought to be an inevitable result of irreversible fibrosis caused by chronic inflammation. However, increased understanding of ... ...

Abstract	The management and understanding of Crohn's disease (CD) continues to evolve quickly. Intestinal strictures were previously thought to be an inevitable result of irreversible fibrosis caused by chronic inflammation. However, increased understanding of the dynamic nature of strictures and of the pathophysiology of this condition has highlighted emerging targets for potential treatment. In the diagnosis of strictures, a distinction must be made between inflammatory and fibrotic types, as the former may respond to medical therapy. Emerging technologies, such as dual-energy computed tomography enterography and iodine density, have allowed more accurate characterization of strictures. Surgical and endoscopic treatment remains the mainstay for fibrotic strictures, but developments in systemic and intralesional biologic therapy have shown efficacy. This article reviews the pathophysiology of this debilitating complication of CD as well as current and emerging diagnostics and treatments.
Language	English
Publishing date	2022-03-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	2386402-3
ISSN	1554-7914
ISSN	1554-7914
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Article ; Online: Dual-Energy, Spectral and Photon Counting Computed Tomography for Evaluation of the Gastrointestinal Tract.

Nehra, Avinash K / Dane, Bari / Yeh, Benjamin M / Fletcher, Joel G / Leng, Shuai / Mileto, Achille

Radiologic clinics of North America

2023 Volume 61, Issue 6, Page(s) 1031–1049

Abstract: The use of dual-energy computed tomography (CT) allows for reconstruction of energy- and material-specific image series. The combination of low-energy monochromatic images, iodine maps, and virtual unenhanced images can improve lesion detection and ... ...

Abstract	The use of dual-energy computed tomography (CT) allows for reconstruction of energy- and material-specific image series. The combination of low-energy monochromatic images, iodine maps, and virtual unenhanced images can improve lesion detection and disease characterization in the gastrointestinal tract in comparison with single-energy CT.
Language	English
Publishing date	2023-07-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	215712-3
ISSN	1557-8275 ; 0033-8389
ISSN (online)	1557-8275
ISSN	0033-8389
DOI	10.1016/j.rcl.2023.06.002
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