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Article ; Online: Health insurance as a moderator in the relationship between financial toxicity and medical cost-coping behaviors: Evidence from patients with lung cancer in China.

Cui, Yongchun / Lv, Jingjing / Hu, Xiaoyu / Zhu, Dawei

2024

Abstract: Objective: This study investigates the relationship between financial toxicity and medical cost-coping behaviors (MCCB) in Chinese patients with lung cancer, with a particular focus on the moderating role of health insurance.: Methods: We surveyed ... ...

Abstract	Objective: This study investigates the relationship between financial toxicity and medical cost-coping behaviors (MCCB) in Chinese patients with lung cancer, with a particular focus on the moderating role of health insurance. Methods: We surveyed 218 patients with lung cancer and assessed their Comprehensive Score for Financial Toxicity (COST) and self-reported MCCB. Patients were categorized into Urban Employee's Basic Medical Insurance (UEBMI) group and Urban-Rural Resident Basic Medical Insurance Scheme (URRBMI) groups by their medical insurance, and matched for socioeconomic, demographic, and disease characteristics via propensity score. Results: Significant different characteristics were noted between UEBMI patients and URRBMI patients. Patients with UEBMI had higher COST scores but lower levels of MCCB compared to URRBMI patients in the original dataset. After data matching, multivariate logit regression analysis showed that better financial toxicity was associated with lower levels of MCCB (OR = 0.95, 95% CI: 0.92-0.99). Health insurance type did not have a direct association with cost-coping behaviors, but an interaction was observed between health insurance type and financial toxicity. Among patients with URRBMI, better financial toxicity was associated with lower levels of cost-coping behaviors (OR = 0.89, 95% CI: 0.83-0.95). Patients with UEBMI had a lower probability of engaging in any cost-coping behaviors in situations of worse financial toxicity compared to patients with URRBMI. Conclusion: The findings suggest that financial toxicity is correlated with MCCB in Chinese patients with lung cancer. The type of health insurance, specifically UEBMI and URRBMI, plays a moderating role in this relationship. Understanding these dynamics is essential for developing targeted interventions and policies to mitigate financial toxicity and improve patients' management of medical costs.
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2659751-2
ISSN	2045-7634 ; 2045-7634
ISSN (online)	2045-7634
ISSN	2045-7634
DOI	10.1002/cam4.6911
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: RNA sequencing identifies key genes involved in intramuscular fat deposition in chickens at different developmental stages.

Zhu, Jinmei / Wang, Yongli / Su, Yongchun / Zheng, Maiqing / Cui, Huanxian / Chen, Zhiwu

BMC genomics

2024 Volume 25, Issue 1, Page(s) 219

Abstract: Background: Intramuscular fat (IMF) is an important factor in meat quality, and triglyceride (TG) and Phospholipids (PLIP), as the main components of IMF, are of great significance to the improvement of meat quality.: Results: In this study, we used ... ...

Abstract	Background: Intramuscular fat (IMF) is an important factor in meat quality, and triglyceride (TG) and Phospholipids (PLIP), as the main components of IMF, are of great significance to the improvement of meat quality. Results: In this study, we used 30 RNA sequences generated from the transcriptome of chicken breast muscle tissues at different developmental stages to construct a gene expression matrix to map RNA sequence reads to the chicken genome and identify the transcript of origin. We used weighted gene co-expression network analysis (WGCNA) and identified 27 co-expression modules, 10 of which were related to TG and PLIP. We identified 150 highly-connected hub genes related to TG and PLIP, respectively, which were found to be mainly enriched in the adipocytokine signaling pathway, MAPK signaling pathway, mTOR signaling pathway, FoxO signaling pathway, and TGF-beta signaling pathway. Additionally, using the BioMart database, we identified 134 and 145 candidate genes related to fat development in the TG-related module and PLIP-related module, respectively. Among them, RPS6KB1, BRCA1, CDK1, RPS3, PPARGC1A, ACSL1, NDUFAB1, NDUFA9, ATP5B and PRKAG2 were identified as candidate genes related to fat development and highly-connected hub genes in the module, suggesting that these ten genes may be important candidate genes affecting IMF deposition. Conclusions: RPS6KB1, BRCA1, CDK1, RPS3, PPARGC1A, ACSL1, NDUFAB1, NDUFA9, ATP5B and PRKAG2 may be important candidate genes affecting IMF deposition. The purpose of this study was to identify the co-expressed gene modules related to chicken IMF deposition using WGCNA and determine key genes related to IMF deposition, so as to lay a foundation for further research on the molecular regulation mechanism underlying chicken fat deposition.
MeSH term(s)	Animals ; Chickens/genetics ; Chickens/metabolism ; Muscles/metabolism ; Gene Expression Profiling ; Gene Regulatory Networks ; Sequence Analysis, RNA
Language	English
Publishing date	2024-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2041499-7
ISSN	1471-2164 ; 1471-2164
ISSN (online)	1471-2164
ISSN	1471-2164
DOI	10.1186/s12864-023-09819-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: New Method for a SEM-Based Characterization of Helical-Fiber Nonwovens.

Li, Ying / Cui, Guixin / Zeng, Yongchun

Polymers

2022 Volume 14, Issue 16

Abstract: The lack of tools particularly designed for the quantification of the fiber morphology in nonwovens, especially the multi-level structured fibers, is the main reason for the limited research studies on the establishment of realistic nonwoven structure. ... ...

Abstract	The lack of tools particularly designed for the quantification of the fiber morphology in nonwovens, especially the multi-level structured fibers, is the main reason for the limited research studies on the establishment of realistic nonwoven structure. In this study, two polymers, cellulose acetate (CA) and thermoplastic polyurethane (TPU), which have different molecular flexibility, were chosen to produce nonwovens with helical nanofibers. Focusing on the nonwovens with helical fibers, a soft package was developed to characterize fiber morphologies, including fiber orientation, helix diameter, and curvature of helix. The novelty of this study is the proposal of a method for the characterization of nanofibrous nonwovens with special fiber shape (helical fibers) which can be used for curve fibers. The characterization results for the helical-fiber nonwoven sample and the nonwoven sample with straight fibers were compared and analyzed.
Language	English
Publishing date	2022-08-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym14163370
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Article ; Online: Construction and Verification of Quality Evaluation Indicator System for Extracorporeal Membrane Oxygenation Animal Experimental Platform

WANG Shuo / LÜ Yunhui / WANG Xiaokang / ZHANG Zhenhao / CUI Yongchun

Shiyan dongwu yu bijiao yixue, Vol 43, Iss 6, Pp 604-

2023 Volume 611

Abstract: ObjectiveTo establish a standardized and professional service quality evaluation index system for extracorporeal membrane oxygenation (ECMO) animal experimental platform. Methods The literature research and expert consultation were used to establish a ... ...

Abstract	ObjectiveTo establish a standardized and professional service quality evaluation index system for extracorporeal membrane oxygenation (ECMO) animal experimental platform. Methods The literature research and expert consultation were used to establish a factor set for the quality evaluation of ECMO animal experimental platform. Then, experts used the 1/9-9 scale method to compare and score pair-two indicators. Based on the principles of fuzzy analytic hierarchy process and expert scoring results, the ECMO animal experimental platform quality evaluation system was constructed. In order to verify the actual efficacy of this system, a case study was carried out on the ECMO animal experiment platform of FW Animal Experimental Center (FAEC) laboratory. Results A total of 10 experts were included in this study, the questionnaire recovery rate was 100%, the judgment coefficient (Ca) and familiarity coefficient (Cs) were both greater than 0.50, the expert authority was high (Cr>0.80), the validity test was P<0.01, and the coordination was good. The quality evaluation system of ECMO animal experiment platform includes two levels. There are 4 first-level indicators, with professionalism, safety, functionality, and stability ranked from high to low in terms of their weights. There are 15 second-level indicators, and the top 5 weights are personnel's technical expertise, attractiveness of hardware facility, auditability of data, confidentiality capabilities of data, and professionalism in service process. To facilitate the popularization and application of the system, this study also proposed a "star" system to represent the evaluation results of an ECMO animal experimental platform quality. The quality evaluation system established in this study was used to evaluate the FAEC laboratory as a case study, and the evaluation result was five-star. The actual potency value of FAEC laboratory was 0.910, reaching the five-star level, but the average actual appraisal values of "service continuity" and "sufficiency of project ...
Keywords	extracorporeal membrane oxygenation ; animal experimental platform ; quality evaluation ; Medicine ; R
Subject code	690
Language	Chinese
Publishing date	2023-12-01T00:00:00Z
Publisher	Editorial Office of Laboratory Animal and Comparative Medicine
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Association between cancer health literacy and cancer-related behavior of residents in Shandong, China.

Lu, Youhua / Li, Qiuxia / Liu, Jinhui / Cui, Yongchun / Yang, Jia / Gao, Dongqing / Liu, Jingmin / Ma, Anning / Zhang, Nan / Wang, Jialin

Health promotion international

2024 Volume 39, Issue 1

Abstract: Health literacy is closely related to the incidence of major chronic diseases and its related behaviors such as cancer-related behaviors. This study explored how the cancer health literacy level affects cancer-related behaviors. About one to two villages ...

Abstract	Health literacy is closely related to the incidence of major chronic diseases and its related behaviors such as cancer-related behaviors. This study explored how the cancer health literacy level affects cancer-related behaviors. About one to two villages from six cities of Shandong province were selected as sample areas. Professionals conducted face-to-face interviews with the participants. Finally, 1200 residents completed 1085 effective questionnaires. Data were analysed from a cross-sectional survey in 2019, which included 1085 residents in six cities/counties of Shandong province, China. The result showed that residents with high cancer health literacy were more likely to eat fruits and vegetables frequently, avoid eating moldy food and take exercise. Besides, they were more likely to engage in health education and have a higher willingness to pay for cancer screenings. Most residents in Shandong province have a basic level of cancer health literacy. Improving the cancer health literacy of the population can be an effective strategy to promote a healthier lifestyle, thereby reducing the incidence rates related to cancers.
MeSH term(s)	Humans ; Health Literacy ; Cross-Sectional Studies ; China/epidemiology ; Fruit ; Neoplasms/epidemiology ; Neoplasms/prevention & control
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	1027448-0
ISSN	1460-2245 ; 0957-4824
ISSN (online)	1460-2245
ISSN	0957-4824
DOI	10.1093/heapro/daae008
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Article: Comparative Transcriptomic Analysis Reveals the Regulated Expression Profiles in

Cui, Miao / Wang, Zibin / Yang, Yongchun / Liu, Ru / Wu, Min / Li, Yujie / Zhang, Qizhong / Xu, Delin

Frontiers in genetics

2022 Volume 13, Page(s) 782957

Abstract: Tilapia ( ...

Abstract	Tilapia (
Language	English
Publishing date	2022-03-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606823-0
ISSN	1664-8021
ISSN	1664-8021
DOI	10.3389/fgene.2022.782957
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Article ; Online: Freeze-Thaw Damage Mechanism Analysis of SBS Asphalt Mixture Containing Basalt Fiber and Lignocellulosic Fiber Based on Microscopic Void Characteristics.

Wang, Wensheng / Yang, Liansheng / Cui, Honghai / Wu, Fei / Cheng, Yongchun / Liang, Chunyu

Polymers

2023 Volume 15, Issue 19

Abstract: Freeze-thaw effects pose the significant challenge to asphalt pavement durability, leading to various types of distress and deterioration. This study investigates the freeze-thaw damage mechanism of Styrene-Butadiene-Styrene (SBS) asphalt mixtures ... ...

Abstract	Freeze-thaw effects pose the significant challenge to asphalt pavement durability, leading to various types of distress and deterioration. This study investigates the freeze-thaw damage mechanism of Styrene-Butadiene-Styrene (SBS) asphalt mixtures containing reinforcement fibers, specifically basalt fiber as well as lignocellulosic fiber, through a microscopic void characteristics analysis. This investigation aims to understand how the presence of basalt fiber as well as lignocellulosic fiber influences void characteristics for SBS asphalt mixtures during freeze-thaw cycles. A comprehensive experimental program was conducted for the void and mechanical characteristics, which involved the preparation of SBS asphalt mixtures containing basalt fiber as well as lignocellulosic fiber. The mechanical performances of the two types of asphalt mixtures decrease with more freeze-thaw cycles. The decline is faster initially and gradually slows down. Basalt-fiber-modified SMA-13 has higher air void content and mechanical properties compared to lignocellulosic-fiber-modified SMA-13, indicating that adding basalt fibers improves the mechanical performances of SMA-13 asphalt mixture. Both types of asphalt mixtures experience increasing damage with more freeze-thaw cycles, indicating irreversible damage. The stability damage levels are similar, but basalt-fiber-modified SMA-13 has lower splitting strength damage and stiffness modulus damage compared to lignocellulosic-fiber-modified SMA-13. This suggests that adding basalt fibers enhances the resistance to freeze-thaw damage. Surface wear of asphalt mixtures under repeated freeze-thaw cycles is a complex and dynamic process. Fractal theory can uncover the mechanism of surface wear, while describing surface wear behavior and void deformation characteristics using fractal dimension, angularity, roundness, and aspect ratio is a logical and effective approach. The findings provide insights into freeze-thaw damage mechanisms at the microscopic level, highlighting the effects of reinforcement fibers. They provide valuable insights that can be used to optimize the design and maintenance of asphalt pavements.
Language	English
Publishing date	2023-09-26
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym15193887
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Article ; Online: Freeze–Thaw Damage Mechanism Analysis of SBS Asphalt Mixture Containing Basalt Fiber and Lignocellulosic Fiber Based on Microscopic Void Characteristics

Wensheng Wang / Liansheng Yang / Honghai Cui / Fei Wu / Yongchun Cheng / Chunyu Liang

Polymers, Vol 15, Iss 3887, p

2023 Volume 3887

Abstract: Freeze–thaw effects pose the significant challenge to asphalt pavement durability, leading to various types of distress and deterioration. This study investigates the freeze–thaw damage mechanism of Styrene–Butadiene–Styrene (SBS) asphalt mixtures ... ...

Abstract	Freeze–thaw effects pose the significant challenge to asphalt pavement durability, leading to various types of distress and deterioration. This study investigates the freeze–thaw damage mechanism of Styrene–Butadiene–Styrene (SBS) asphalt mixtures containing reinforcement fibers, specifically basalt fiber as well as lignocellulosic fiber, through a microscopic void characteristics analysis. This investigation aims to understand how the presence of basalt fiber as well as lignocellulosic fiber influences void characteristics for SBS asphalt mixtures during freeze–thaw cycles. A comprehensive experimental program was conducted for the void and mechanical characteristics, which involved the preparation of SBS asphalt mixtures containing basalt fiber as well as lignocellulosic fiber. The mechanical performances of the two types of asphalt mixtures decrease with more freeze–thaw cycles. The decline is faster initially and gradually slows down. Basalt-fiber-modified SMA-13 has higher air void content and mechanical properties compared to lignocellulosic-fiber-modified SMA-13, indicating that adding basalt fibers improves the mechanical performances of SMA-13 asphalt mixture. Both types of asphalt mixtures experience increasing damage with more freeze–thaw cycles, indicating irreversible damage. The stability damage levels are similar, but basalt-fiber-modified SMA-13 has lower splitting strength damage and stiffness modulus damage compared to lignocellulosic-fiber-modified SMA-13. This suggests that adding basalt fibers enhances the resistance to freeze–thaw damage. Surface wear of asphalt mixtures under repeated freeze–thaw cycles is a complex and dynamic process. Fractal theory can uncover the mechanism of surface wear, while describing surface wear behavior and void deformation characteristics using fractal dimension, angularity, roundness, and aspect ratio is a logical and effective approach. The findings provide insights into freeze–thaw damage mechanisms at the microscopic level, highlighting the effects of ...
Keywords	SBS asphalt ; basalt fiber ; lignocellulosic fiber ; void characteristics ; freeze–thaw damage ; Organic chemistry ; QD241-441
Subject code	621
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: High-sensitivity humidity sensing of a U-shaped microfiber coated with porous methacryloxyethyl trimethyl ammonium chloride film.

Cui, Danting / Huang, Sihuan / Cheng, Hongdao / Zheng, Huadan / Zhu, Wenguo / Yu, Jianhui / Zhong, Yongchun / Chen, Zhe

Applied optics

2023 Volume 62, Issue 23, Page(s) 6106–6112

Abstract: We demonstrate an intensity-modulated humidity sensor based on a U-shaped microfiber coated with porous methacryloxyethyl trimethyl ammonium chloride (DMC) film. The high surface-to-volume ratios of the porous structure improve the interaction between ... ...

Abstract	We demonstrate an intensity-modulated humidity sensor based on a U-shaped microfiber coated with porous methacryloxyethyl trimethyl ammonium chloride (DMC) film. The high surface-to-volume ratios of the porous structure improve the interaction between the DMC film and water molecules, resulting in significantly enhanced sensitivity of the humidity sensor. In the humidity range of 34.0%RH to 50.0%RH, the humidity sensitivity of this microfiber sensor is up to 3.090 dB/%RH, which is six times higher than that of other fiber humidity sensors. The humidity detection range can be adjusted with high humidity sensitivity (≥1.685
Language	English
Publishing date	2023-09-14
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.493488
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Single Posterior Surgery Versus Combined Posterior-Anterior Surgery for Lumbar Tuberculosis Patients.

Duan, Dapeng / Cui, Yaqing / Gong, Liqun / Fan, Yayi / Liu, Jun / Zhou, Yongchun / Li, Weiwei

Orthopaedic surgery

2023 Volume 15, Issue 3, Page(s) 868–877

Abstract: Objective: Posterior approach of debridement, interbody graft, and instrumentation, and combined posterior-anterior approach of posterior instrumentation and anterior debridement and interbody graft are two essential surgeries for the surgical treatment ...

Abstract	Objective: Posterior approach of debridement, interbody graft, and instrumentation, and combined posterior-anterior approach of posterior instrumentation and anterior debridement and interbody graft are two essential surgeries for the surgical treatment of spinal tuberculosis (TB), and, until now, which one should be chosen is still controversial. This study aimed to compare the therapeutic efficacy between the single posterior surgery and combined posterior-anterior surgery for lumbar tuberculosis (LTB) patients to elucidate the role of debridement and the effects that result from posterior structure resection. Methods: One hundred and nineteen LTB patients managed with single posterior debridement, interbody graft, and instrumentation surgery (Group P, 73 cases), or combined posterior-anterior surgery of posterior instrumentation and anterior debridement and interbody graft (Group P-A, 46 cases) from January 2008 to December 2016 were retrospectively analyzed. Different indexes were compared between the two groups to evaluate the curative effect and explore the role of debridement and the effects that result from posterior structure resection: operation time, blood loss, visual analog scale (VAS), Japanese Orthopaedic Association (JOA), Erythrocyte Sedimentation Rate (ESR), C-reactive Protein (CRP), surgical complication type and rate, spinopelvic sagittal parameters (local kyphosis [LK], pelvic incidence [PI] and pelvic tilt [PT], lumbar lordosis [LL], and sacral slope [SS]), drainage retention duration, hospital stay, time of abscess disappearance, time of activity recovery, and time of bone graft fusion by t-test or χ Results: The follow-up period ranged from 24 to 60 months. No significant variations were detected between the two groups for age, sex ratio, BMI, disease duration, indication, and the preoperative values of VAS, JOA, ESR, CRP, and LK (p > 0.05). The VAS, JOA, ESR, and CRP significantly improved in both groups after the operation (p < 0.05), along with the LK and LL (p < 0.05). Meanwhile, the SS, PI, and PT showed minor improvement after the operation (p > 0.05). Compared to the P-A group, the P group had shorter operation time and less blood loss and hospital stay (p < 0.05). However, both groups presented similar VAS, JOA, ESR, CRP, and LK improvements (p > 0.05). Additionally, the surgical complication type and rate, postoperative spinopelvic sagittal parameters, and bone graft fusion time did not differ between the two groups (p > 0.05). On the other hand, the patients in the P-A group had a shorter time of abscess disappearance and activity recovery (p < 0.05) but a similar time of drainage retention (p > 0.05) compared to the P group. Conclusion: Both single posterior and combined posterior-anterior surgeries presented a good therapeutic effect for LTB patients with a low surgical complication rate and good quality of LK correction and LL reconstruction and maintenance. Moreover, single posterior surgery was less traumatic than combined posterior-anterior surgery but with slower TB lesion healing and activity recovery. Compared to debridement, stability seems to be more vital for STB healing, posterior structure resection does not affect the effect of spinopelvic realignment.
MeSH term(s)	Humans ; Retrospective Studies ; Abscess/etiology ; Treatment Outcome ; Spinal Fusion/adverse effects ; Lordosis/etiology ; Tuberculosis, Spinal/surgery ; Kyphosis/etiology ; Debridement ; Lumbar Vertebrae/surgery
Language	English
Publishing date	2023-01-19
Publishing country	Australia
Document type	Journal Article
ZDB-ID	2503162-4
ISSN	1757-7861 ; 1757-7853 ; 1757-7861
ISSN (online)	1757-7861 ; 1757-7853
ISSN	1757-7861
DOI	10.1111/os.13628
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