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  1. Article: Chemical Peels in Skin Cancer: A Review.

    Sidiropoulou, Polytimi / Gregoriou, Stamatis / Rigopoulos, Dimitris / Kontochristopoulos, Georgios

    The Journal of clinical and aesthetic dermatology

    2020  Volume 13, Issue 2, Page(s) 53–57

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-02-01
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1941-2789
    ISSN 1941-2789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nails with bloodstained discoloration.

    Gregoriou, Stamatios / Platsidaki, Eftychia / Sidiropoulou, Polytimi / Rigopoulos, Dimitrios

    BMJ (Clinical research ed.)

    2021  Volume 375, Page(s) n1951

    MeSH term(s) Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Diagnosis, Differential ; Docetaxel/administration & dosage ; Docetaxel/adverse effects ; Female ; Hemorrhage/diagnosis ; Humans ; Middle Aged ; Nail Diseases/chemically induced ; Nail Diseases/diagnosis ; Nail Diseases/psychology ; Nail Diseases/therapy ; Onycholysis/diagnosis ; Onycholysis/etiology ; Patient Care Management ; Pigmentation Disorders/chemically induced ; Pigmentation Disorders/diagnosis ; Pigmentation Disorders/psychology ; Pigmentation Disorders/therapy ; Quality of Life ; Remission, Spontaneous ; Withholding Treatment
    Chemical Substances Antineoplastic Agents ; Docetaxel (15H5577CQD)
    Language English
    Publishing date 2021-10-13
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.n1951
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Psoriasis immunometabolism: progress on metabolic biomarkers and targeted therapy.

    Sarandi, Evangelia / Krueger-Krasagakis, Sabine / Tsoukalas, Dimitris / Sidiropoulou, Polytimi / Evangelou, George / Sifaki, Maria / Rudofsky, Gottfried / Drakoulis, Nikolaos / Tsatsakis, Aristidis

    Frontiers in molecular biosciences

    2023  Volume 10, Page(s) 1201912

    Abstract: Psoriasis is a common inflammatory disease that affects mainly the skin. However, the moderate to severe forms have been associated with several comorbidities, such as psoriatic arthritis, Crohn's disease, metabolic syndrome and cardiovascular disease. ... ...

    Abstract Psoriasis is a common inflammatory disease that affects mainly the skin. However, the moderate to severe forms have been associated with several comorbidities, such as psoriatic arthritis, Crohn's disease, metabolic syndrome and cardiovascular disease. Keratinocytes and T helper cells are the dominant cell types involved in psoriasis development via a complex crosstalk between epithelial cells, peripheral immune cells and immune cells residing in the skin. Immunometabolism has emerged as a potent mechanism elucidating the aetiopathogenesis of psoriasis, offering novel specific targets to diagnose and treat psoriasis early. The present article discusses the metabolic reprogramming of activated T cells, tissue-resident memory T cells and keratinocytes in psoriatic skin, presenting associated metabolic biomarkers and therapeutic targets. In psoriatic phenotype, keratinocytes and activated T cells are glycolysis dependent and are characterized by disruptions in the TCA cycle, the amino acid metabolism and the fatty acid metabolism. Upregulation of the mammalian target of rapamycin (mTOR) results in hyperproliferation and cytokine secretion by immune cells and keratinocytes. Metabolic reprogramming through the inhibition of affected metabolic pathways and the dietary restoration of metabolic imbalances may thus present a potent therapeutic opportunity to achieve long-term management of psoriasis and improved quality of life with minimum adverse effects.
    Language English
    Publishing date 2023-06-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2023.1201912
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  4. Article ; Online: Topical mechlorethamine in mycosis fungoides: a prospective clinical, histopathological, and molecular analysis of 13 cases.

    Sidiropoulou, Polytimi / Marinos, Leonidas / Gerochristou, Maria / Economaki, Elizabeth / Papanikolaou, Asimina / Voudouri, Dimitra / Kalliambou, Styliani / Stratigos, Alexander / Nikolaou, Vasiliki

    European journal of cancer (Oxford, England : 1990)

    2021  Volume 156 Suppl 1, Page(s) S61–S62

    Language English
    Publishing date 2021-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/S0959-8049(21)00742-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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    Zs.MO 583: Show issues

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  5. Article ; Online: New insights into granulomatous mycosis fungoides (GMF): a single-center experience.

    Sidiropoulou, Polytimi / Tsaoutou, Katerina / Constantinou, Andria / Marinos, Leonidas / Voudouri, Dimitra / Iliakis, Theodoros / Kanellis, George / Pouliou, Evi / Stratigos, Alexander / Nikolaou, Vasiliki

    European journal of cancer (Oxford, England : 1990)

    2021  Volume 156 Suppl 1, Page(s) S69–S70

    Language English
    Publishing date 2021-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/S0959-8049(21)00757-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 583: Show issues

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  6. Article: Management Strategies Of Palmar Hyperhidrosis: Challenges And Solutions.

    Gregoriou, Stamatios / Sidiropoulou, Polytimi / Kontochristopoulos, Georgios / Rigopoulos, Dimitrios

    Clinical, cosmetic and investigational dermatology

    2019  Volume 12, Page(s) 733–744

    Abstract: Palmar hyperhidrosis is a potentially disabling condition for which management remains a therapeutic challenge. Given the significant impact on quality of life, various treatment options are available, ranging from topical agents and medical devices to ... ...

    Abstract Palmar hyperhidrosis is a potentially disabling condition for which management remains a therapeutic challenge. Given the significant impact on quality of life, various treatment options are available, ranging from topical agents and medical devices to systemic therapies and surgical interventions. Nonsurgical approaches, i.e. topical antiperspirants, botulinum toxin injections, iontophoresis, and systemic agents, are all supported by the current literature. Patients with mild-to-moderate disease can often benefit from topical therapies only. As disease severity progresses, systemic oral medication, such as anticholinergic drugs, usually becomes necessary. Last-line surgical approaches (sympathetic denervation) should be reserved for severe refractory cases. Recently, therapeutic strategies have been evolving with several new agents emerging as promising alternatives in clinical trials. In practice, however, each modality comes with its own benefits and risks. An individual therapeutic ladder is generally recommended, taking into account disease severity, benefit-to-risk profile, treatment cost, patient preference, and clinician expertise. This review will provide an update on current and emerging concepts of management for excessive hand sweating to help clinicians optimize therapeutic decision-making.
    Language English
    Publishing date 2019-10-04
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S210973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Positron Emission Tomography in Merkel Cell Carcinoma.

    Sachpekidis, Christos / Sidiropoulou, Polytimi / Hassel, Jessica C / Drakoulis, Nikolaos / Dimitrakopoulou-Strauss, Antonia

    Cancers

    2020  Volume 12, Issue 10

    Abstract: Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy usually arising as a nonspecific nodule on sun-exposed areas of the head and neck. Given the poor prognosis of this aggressive tumor, assessment of disease burden in pre- and post- ... ...

    Abstract Merkel cell carcinoma (MCC) is a rare neuroendocrine skin malignancy usually arising as a nonspecific nodule on sun-exposed areas of the head and neck. Given the poor prognosis of this aggressive tumor, assessment of disease burden in pre- and post-treatment care may ensure an optimal management with significant implications for patient surveillance and prognosis. Although imaging has established its role in locally advanced or distant metastatic MCC, a standard imaging algorithm is yet to be determined and respective recommendations are mainly based on melanoma. Positron emission tomography/computed tomography (PET/CT) is increasingly evolving as a valuable imaging tool in metastatic or unresectable MCC, mostly utilizing the glucose analogue
    Language English
    Publishing date 2020-10-09
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers12102897
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Onychotillomania: A Chameleon-Like Disorder: Case Report and Review of Literature.

    Sidiropoulou, Polytimi / Sgouros, Dimitrios / Theodoropoulos, Konstantinos / Katoulis, Alexander / Rigopoulos, Dimitrios

    Skin appendage disorders

    2018  Volume 5, Issue 2, Page(s) 104–107

    Abstract: Onychotillomania, or nail-picking disorder, is an uncommon and misdiagnosed behavioral pattern focused on the nail apparatus. It is demarcated by the compulsive or irresistible urge in patients to constantly injure their own nails, with the fingers or ... ...

    Abstract Onychotillomania, or nail-picking disorder, is an uncommon and misdiagnosed behavioral pattern focused on the nail apparatus. It is demarcated by the compulsive or irresistible urge in patients to constantly injure their own nails, with the fingers or tools, inflicting noticeable or even irreversible self-destruction of the nail unit. Despite its rarity, this self-injurious coercion often poses a diagnostic and therapeutic challenge. Not only do many patients deny nail manipulation, but also the disorder has long been recognized to present itself with a wide range of clinical features, which hampers early and indisputable diagnosis. Furthermore, onychotillomania constitutes a persistent and hardly manageable problem, mostly because of its psychocutaneous nature as well as its high propensity to coexist with underlying neuropsychiatric illnesses or other behavioral disorders. However, the medical literature concerning obsessive nail picking still remains relatively scarce. Herein, we present an extraordinary, yet very intriguing case of a Caucasian patient with onychotillomania and onychophagia coexistence masquerading a weird inflammation-like lesion.
    Language English
    Publishing date 2018-06-25
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2806972-9
    ISSN 2296-9160 ; 2296-9195
    ISSN (online) 2296-9160
    ISSN 2296-9195
    DOI 10.1159/000489941
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  9. Article: Nivolumab in non-small cell lung cancer: A novel case of an erythema annulare centrifugum-like eruption.

    Sidiropoulou, Polytimi / Sgontzou, Themis / Kostara, Ioanna / Sgouros, Dimitrios / Theologi, Barbara / Zouridaki, Eftychia / Kontochristopoulos, Georgios / Rigopoulos, Dimitris / J Stratigos, Alexander

    JAAD case reports

    2019  Volume 5, Issue 7, Page(s) 572–575

    Language English
    Publishing date 2019-06-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2019.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A case of lymphomatoid papulosis, pityriasis lichenoides acuta, and mycosis fungoides coexistence.

    Sidiropoulou, Polytimi / Nikolaou, Vasiliki / Marinos, Leonidas / Voudouri, Dimitra / Economidi, Afroditi / Rigopoulos, Dimitris / Stratigos, Alexander

    The Australasian journal of dermatology

    2018  Volume 60, Issue 2, Page(s) e154–e156

    MeSH term(s) Adult ; Female ; Humans ; Lymphomatoid Papulosis/complications ; Lymphomatoid Papulosis/pathology ; Mycosis Fungoides/complications ; Mycosis Fungoides/pathology ; Pityriasis Lichenoides/complications ; Pityriasis Lichenoides/pathology ; Skin Neoplasms/complications ; Skin Neoplasms/pathology
    Language English
    Publishing date 2018-09-09
    Publishing country Australia
    Document type Case Reports ; Letter
    ZDB-ID 138052-7
    ISSN 1440-0960 ; 0004-8380
    ISSN (online) 1440-0960
    ISSN 0004-8380
    DOI 10.1111/ajd.12925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 236: Show issues Location:
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