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Article ; Online: Electronic mail communication in health care: do old fashioned decorum and style still matter?

Aoun, Salah G / Lall, Rohan R / Batjer, H Hunt / Bendok, Bernard R

2012 Volume 78, Issue 3-4, Page(s) 194–197

MeSH term(s)	Communication ; Delivery of Health Care/standards ; Delivery of Health Care/trends ; Electronic Mail/standards ; Electronic Mail/trends ; Humans ; Language Arts/standards ; Language Arts/trends ; Peer Group ; Professional Practice/standards ; Professional Practice/trends
Language	English
Publishing date	2012-09
Publishing country	United States
Document type	News
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2012.07.001
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Zs.A 1159: Show issues

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Article ; Online: Thoracic spinal cord intramedullary aspergillus invasion and abscess.

McCaslin, Addason F / Lall, Rishi R / Wong, Albert P / Lall, Rohan R / Sugrue, Patrick A / Koski, Tyler R

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2015 Volume 22, Issue 2, Page(s) 404–406

Abstract: Invasive central nervous system aspergillosis is a rare form of fungal infection that presents most commonly in immunocompromised individuals. There have been multiple previous reports of aspergillus vertebral osteomyelitis and spinal epidural ... ...

Abstract	Invasive central nervous system aspergillosis is a rare form of fungal infection that presents most commonly in immunocompromised individuals. There have been multiple previous reports of aspergillus vertebral osteomyelitis and spinal epidural aspergillus abscess; however to our knowledge there are no reports of intramedullary aspergillus infection. We present a 19-year-old woman with active acute lymphoblastic leukemia who presented with several weeks of fevers and bilateral lower extremity weakness. She was found to have an intramedullary aspergillus abscess at T12-L1 resulting from adjacent vertebral osteomyelitis and underwent surgical debridement with ultra-sound guided aspiration and aggressive intravenous voriconazole therapy. To our knowledge this is the first reported case of spinal aspergillosis invading the intramedullary cavity. Though rare, this entity should be included in the differential for immunocompromised patients presenting with fevers and neurologic deficit. Early recognition with aggressive neurosurgical intervention and antifungal therapy may improve outcomes in future cases.
MeSH term(s)	Abscess/microbiology ; Abscess/pathology ; Antifungal Agents/therapeutic use ; Fatal Outcome ; Female ; Fever/etiology ; Humans ; Muscle Weakness/etiology ; Neuroaspergillosis/drug therapy ; Neuroaspergillosis/microbiology ; Neuroaspergillosis/pathology ; Osteomyelitis/microbiology ; Osteomyelitis/pathology ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/complications ; Spinal Cord/microbiology ; Spinal Cord/pathology ; Suction ; Thoracic Vertebrae/microbiology ; Thoracic Vertebrae/pathology ; Voriconazole/therapeutic use ; Young Adult
Chemical Substances	Antifungal Agents ; Voriconazole (JFU09I87TR)
Language	English
Publishing date	2015-02
Publishing country	Scotland
Document type	Case Reports ; Journal Article
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2014.04.030
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Zs.A 3999: Show issues

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Article ; Online: Evidence-based management of deep wound infection after spinal instrumentation.

Lall, Rishi R / Wong, Albert P / Lall, Rohan R / Lawton, Cort D / Smith, Zachary A / Dahdaleh, Nader S

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2015 Volume 22, Issue 2, Page(s) 238–242

Abstract: In this study, evidence-based medicine is used to assess optimal surgical and medical management of patients with post-operative deep wound infection following spinal instrumentation. A computerized literature search of the PubMed database was performed. ...

Abstract	In this study, evidence-based medicine is used to assess optimal surgical and medical management of patients with post-operative deep wound infection following spinal instrumentation. A computerized literature search of the PubMed database was performed. Twenty pertinent studies were identified. Studies were separated into publications addressing instrumentation retention versus removal and publications addressing antibiotic therapy regimen. The findings were classified based on level of evidence (I-III) and findings were summarized into evidentiary tables. No level I or II evidence was identified. With regards to surgical management, five studies support instrumentation retention in the setting of early deep infection. In contrast, for delayed infection, the evidence favors removal of instrumentation at the time of initial debridement. Surgeons should be aware that for deformity patients, even if solid fusion is observed, removal of instrumentation may be associated with significant loss of correction. A course of intravenous antibiotics followed by long-term oral suppressive therapy should be pursued if instrumentation is retained. A shorter treatment course may be appropriate if hardware is removed.
MeSH term(s)	Adult ; Anti-Bacterial Agents/therapeutic use ; Evidence-Based Medicine ; Humans ; Male ; Retrospective Studies ; Spinal Fusion/adverse effects ; Spinal Fusion/instrumentation ; Surgical Wound Infection/etiology ; Surgical Wound Infection/therapy
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2015-02
Publishing country	Scotland
Document type	Journal Article ; Review
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2014.07.010
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Zs.A 3999: Show issues

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Article ; Online: Delayed malignant transformation of petroclival meningioma to chondrosarcoma after stereotactic radiosurgery.

Lall, Rohan R / Lall, Rishi R / Smith, Timothy R / Lee, Kyung-Hwa / Mao, Qinwen / Kalapurakal, John A / Marymont, Maryanne H / Chandler, James P

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2014 Volume 21, Issue 7, Page(s) 1225–1228

Abstract: Stereotactic radiosurgery (SRS) is often used as adjuvant treatment for residual or recurrent tumor following microsurgical resection of posterior fossa meningiomas. SRS is associated with excellent rates of local control, however long-term complications ...

Abstract	Stereotactic radiosurgery (SRS) is often used as adjuvant treatment for residual or recurrent tumor following microsurgical resection of posterior fossa meningiomas. SRS is associated with excellent rates of local control, however long-term complications remain unclear. Secondary malignancy is an often discussed but rarely described complication of SRS. We present a 56-year-old woman who underwent near total resection of a petroclival meningioma, followed by two episodes of SRS over the ensuing 8 years for local recurrence. She returned 14 years after initial diagnosis with neurologic deterioration and was found to have massive recurrence. Pathology was consistent with high-grade chondrosarcoma. The tumor continued to progress despite debulking and proton-beam therapy and the patient died of medical complications. To our knowledge this is the first report of malignant transformation of a meningioma to high-grade chondrosarcoma, further notable due to the remarkable clinical course and delayed presentation after initial surgery and radiosurgery. Though this may have been a de novo tumor, it is also possible that this represents a case of radiation-induced neoplasm. Although SRS continues to gain favor as a treatment modality, delayed malignant degeneration is a potential complication and physicians should counsel patients of this risk.
MeSH term(s)	Chondrosarcoma/prevention & control ; Chondrosarcoma/secondary ; Female ; Humans ; Magnetic Resonance Imaging ; Meningeal Neoplasms/pathology ; Meningeal Neoplasms/surgery ; Meningioma/pathology ; Meningioma/surgery ; Middle Aged ; Neoplasm Recurrence, Local/prevention & control ; Neoplasm Recurrence, Local/secondary ; Radiosurgery/methods
Language	English
Publishing date	2014-07
Publishing country	Scotland
Document type	Case Reports ; Journal Article
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2013.11.015
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Zs.A 3999: Show issues

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Article: Low-Dose Gamma Knife Radiosurgery for Vestibular Schwannomas: Tumor Control and Cranial Nerve Function Preservation After 11 Gy.

Schumacher, Andrew J / Lall, Rohan R / Lall, Rishi R / Nanney, Allan / Ayer, Amit / Sejpal, Samir / Liu, Benjamin P / Marymont, Maryanne / Lee, Plato / Bendok, Bernard R / Kalapurakal, John A / Chandler, James P

Journal of neurological surgery. Part B, Skull base

2016 Volume 78, Issue 1, Page(s) 2–10

Abstract: Objectives: This study aims to report tumor control rates and cranial nerve function after low dose (11.0 Gy) Gamma knife radiosurgery (GKRS) in patients with vestibular schwannomas.: Methods: A retrospective chart review was performed on 30 ... ...

Abstract	Objectives: This study aims to report tumor control rates and cranial nerve function after low dose (11.0 Gy) Gamma knife radiosurgery (GKRS) in patients with vestibular schwannomas. Methods: A retrospective chart review was performed on 30 consecutive patients with vestibular schwannomas treated from March 2004 to August 2010 with GKRS at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University. The marginal dose for all patients was 11.0 Gy prescribed to the 50% isodose line. Median follow-up time was 42 months. The median treatment volume was 0.53 cm3. Hearing data were obtained from audiometry reports before and after radiosurgery. Results: The actuarial progression free survival (PFS) based on freedom from surgery was 100% at 5 years. PFS based on freedom from persistent growth was 91% at 5 years. One patient experienced tumor progression requiring resection at 87 months. Serviceable hearing, defined as Gardner-Robertson score of I-II, was preserved in 50% of patients. On univariate and multivariate analyses, only higher mean and maximum dose to the cochlea significantly decreased the proportion of patients with serviceable hearing. Conclusion: Vestibular schwannomas can be treated with low doses (11.0 Gy) of GKRS with good tumor control and cranial nerve preservation.
Language	English
Publishing date	2016-05-31
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2654269-9
ISSN	2193-634X ; 2193-6331
ISSN (online)	2193-634X
ISSN	2193-6331
DOI	10.1055/s-0036-1584231
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Zs.A 3425: Show issues

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Article ; Online: Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review.

Lee, Kyung-Hwa / Lall, Rohan R / Chandler, James P / Bigio, Eileen H / Mao, Qinwen

Neuropathology : official journal of the Japanese Society of Neuropathology

2013 Volume 33, Issue 2, Page(s) 192–198

Abstract: Chordoid meningioma is an uncommon variant of meningioma, and is very rarely found in the pineal region. We report a case of pineal region chordoid meningioma occurring in a young woman complicated by repetitive hemorrhages in the setting of pregnancy. A ...

Abstract	Chordoid meningioma is an uncommon variant of meningioma, and is very rarely found in the pineal region. We report a case of pineal region chordoid meningioma occurring in a young woman complicated by repetitive hemorrhages in the setting of pregnancy. A 23-year-old woman, 28 weeks pregnant, was transferred to our hospital for further management of a multi-septated, hemorrhagic pineal region mass and hydrocephalus. MRI revealed a heterogeneous T2-hyperintense lesion measuring 1.7 × 1.7 cm in the pineal gland. Resection of the tumor through an occipital transtentorial approach was performed. Histopathologic examination of the lesion confirmed the diagnosis of chordoid meningioma demonstrating cords and clusters of eosinophilic cells with rare cytoplasmic vacuolation arranged in a mucinous stroma. Additionally, there was abundant lymphoplasmacytic infiltration within the tumor. The details of this case are presented with a review of the literature.
MeSH term(s)	Brain Neoplasms/complications ; Brain Neoplasms/diagnosis ; Brain Neoplasms/surgery ; Cerebral Hemorrhage/complications ; Cerebral Hemorrhage/diagnosis ; Cerebral Hemorrhage/surgery ; Female ; Humans ; Infant, Newborn ; Male ; Meningeal Neoplasms/complications ; Meningeal Neoplasms/diagnosis ; Meningeal Neoplasms/surgery ; Meningioma/complications ; Meningioma/diagnosis ; Meningioma/surgery ; Pinealoma/complications ; Pinealoma/diagnosis ; Pinealoma/surgery ; Pregnancy ; Pregnancy Complications, Neoplastic/diagnosis ; Pregnancy Complications, Neoplastic/surgery ; Young Adult
Language	English
Publishing date	2013-04
Publishing country	Australia
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	1483794-8
ISSN	1440-1789 ; 0919-6544
ISSN (online)	1440-1789
ISSN	0919-6544
DOI	10.1111/j.1440-1789.2012.01337.x
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Zs.A 5086: Show issues

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Article ; Online: Minimally invasive thoracic corpectomy: surgical strategies for malignancy, trauma, and complex spinal pathologies.

Lall, Rohan R / Smith, Zachary A / Wong, Albert P / Miller, Daniel / Fessler, Richard G

Minimally invasive surgery

2012 Volume 2012, Page(s) 213791

Abstract: The rapid expansion of minimally invasive techniques for corpectomy in the thoracic spine provides promise to redefine treatment options in this region. Techniques have evolved permitting anterior, lateral, posterolateral, and midline posterior ... ...

Abstract	The rapid expansion of minimally invasive techniques for corpectomy in the thoracic spine provides promise to redefine treatment options in this region. Techniques have evolved permitting anterior, lateral, posterolateral, and midline posterior corpectomy in a minimally invasive fashion. We review the numerous techniques that have been described, including thoracoscopy, tubular retraction, and various instrumentation techniques. Minimally invasive techniques are compared to their open predecessors from a technical and complication standpoint. Advantages and disadvantages of different approaches are also considered, with an emphasis on surgical strategies and nuance.
Language	English
Publishing date	2012-07-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2627964-2
ISSN	2090-1453 ; 2090-1453
ISSN (online)	2090-1453
ISSN	2090-1453
DOI	10.1155/2012/213791
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Article ; Online: The quest for precision medicine: towards a "standard model" of aneurysm risk prediction.

El Ahmadieh, Tarek Y / El Tecle, Najib E / Lall, Rohan R / Wong, Albert P / Bendok, Bernard R

Neurosurgery

2013 Volume 73, Issue 4, Page(s) N11–2

MeSH term(s)	Aneurysm, Ruptured/epidemiology ; Humans ; Intracranial Aneurysm/complications ; Risk Factors ; Rupture, Spontaneous/epidemiology ; Subarachnoid Hemorrhage/epidemiology ; Subarachnoid Hemorrhage/etiology
Language	English
Publishing date	2013-10
Publishing country	United States
Document type	News
ZDB-ID	135446-2
ISSN	1524-4040 ; 0148-396X
ISSN (online)	1524-4040
ISSN	0148-396X
DOI	10.1227/01.neu.0000435112.26145.3a
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Zs.A 1424: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 539: Show issues

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Article ; Online: Review on machine learning-based bioprocess optimization, monitoring, and control systems.

Pratim Mondal, Partha / Galodha, Abhinav / Kumar Verma, Vishal / Singh, Vijai / Loke Show, Pau / Kumar Awasthi, Mukesh / Lall, Brejesh / Anees, Sanya / Pollmann, Katrin / Jain, Rohan

Bioresource technology

2022 , Page(s) 128523

Abstract: Machine Learning is quickly becoming an impending game changer for transforming big data thrust from the bioprocessing industry into actionable output. However, the complex data set from bioprocess, lagging cyber-integrated sensor system, and issues with ...

Abstract	Machine Learning is quickly becoming an impending game changer for transforming big data thrust from the bioprocessing industry into actionable output. However, the complex data set from bioprocess, lagging cyber-integrated sensor system, and issues with storage scalability limit machine learning real-time application. Hence, it is imperative to know the state of technology to address prevailing issues. This review first gives an insight into the basic understanding of the machine learning domain and discusses its complexities for more comprehensive applications. Followed by an outline of how relevant machine learning models are for statistical and logical analysis of the enormous datasets generated to control bioprocess operations. Then this review critically discusses the current knowledge, its limitations, and future aspects in different subfields of the bioprocessing industry. Further, this review discusses the prospects of adopting a hybrid method to dovetail different modeling strategies, cyber-networking, and integrated sensors to develop new digital biotechnologies.
Language	English
Publishing date	2022-12-21
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1065195-0
ISSN	1873-2976 ; 0960-8524
ISSN (online)	1873-2976
ISSN	0960-8524
DOI	10.1016/j.biortech.2022.128523
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Z 3258: Show issues

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Article ; Online: Minimally Invasive Thoracic Corpectomy

Richard G. Fessler / Daniel Miller / Albert P. Wong / Zachary A. Smith / Rohan R. Lall

Minimally Invasive Surgery, Vol

Surgical Strategies for Malignancy, Trauma, and Complex Spinal Pathologies

2012 Volume 2012

Keywords	Surgery ; RD1-811 ; Medicine ; R ; DOAJ:Surgery ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
Language	English
Publishing date	2012-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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