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  1. Article ; Online: Commentary.

    Papanikolaou, Ioannis S

    Endoscopy

    2021  Volume 53, Issue 10, Page(s) 1091

    Language English
    Publishing date 2021-09-22
    Publishing country Germany
    Document type Journal Article ; Comment
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1526-9347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 669: Show issues Location:
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  2. Article: Commentary

    Papanikolaou, Ioannis S.

    Endoscopy

    2021  Volume 53, Issue 10, Page(s) 1091–1091

    Language English
    Publishing date 2021-09-22
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1526-9347
    Database Thieme publisher's database

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  3. Article ; Online: Gastric Outlet Obstruction: Current Status and Future Directions.

    Papanikolaou, Ioannis S / Siersema, Peter D

    Gut and liver

    2022  Volume 16, Issue 5, Page(s) 667–675

    Abstract: Gastric outlet obstruction (GOO) is a relatively common condition in which mechanical obstruction of the pylorus, distal stomach, or duodenum causes severe symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its etiology includes both ... ...

    Abstract Gastric outlet obstruction (GOO) is a relatively common condition in which mechanical obstruction of the pylorus, distal stomach, or duodenum causes severe symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its etiology includes both benign and malignant disorders. Currently, GOO has many treatment options, including initial conservative therapeutic protocols and more invasive procedures, such as surgical gastroenterostomy, stent placement and, the most recently implemented procedure, endoscopic ultrasound-guided gastroenterostomy (EUS-GE). Each procedure has its merits, with surgery often prevailing in patients with longer life expectancy and stents being used most often in patients with malignant gastric outlet stenosis. The newly developed EUS-GE combines the immediate effect of stents and the long-term efficacy of gastroenterostomy. However, this novel method is a technically demanding process that requires expert experience and special facilities. Thus, the true clinical effectiveness, as well as the duration of the effects of EUS-GE, still need to be determined.
    MeSH term(s) Endosonography/methods ; Gastric Outlet Obstruction/etiology ; Gastric Outlet Obstruction/surgery ; Gastroenterostomy/adverse effects ; Gastroenterostomy/methods ; Humans ; Pylorus/surgery ; Stents/adverse effects
    Language English
    Publishing date 2022-03-22
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2399010-7
    ISSN 2005-1212 ; 1976-2283
    ISSN (online) 2005-1212
    ISSN 1976-2283
    DOI 10.5009/gnl210327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6610: Show issues Location:
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  4. Article ; Online: When rare diseases crisscross within the same patient: von Hippel-Lindau and type 1 gastric neuroendocrine tumor.

    Alexandraki, Krystallenia I / Spyroglou, Ariadni / Xekouki, Paraskevi / Bramis, Konstantinos I / Kyriakopoulos, Georgios / Barkas, Konstantinos / Papanikolaou, Ioannis S / Mastorakos, George / Konstadoulakis, Manousos

    Hormones (Athens, Greece)

    2024  

    Abstract: Von-Hippel-Lindau (VHL) is a genetic multisystem disorder characterized by visceral cysts and benign and malignant tumors in various organs. Herein, we present the case of a 23-year-old woman with VHL presenting with multiple gastric neuroendocrine ... ...

    Abstract Von-Hippel-Lindau (VHL) is a genetic multisystem disorder characterized by visceral cysts and benign and malignant tumors in various organs. Herein, we present the case of a 23-year-old woman with VHL presenting with multiple gastric neuroendocrine neoplasms (gNENs) type 1 in the context of chronic autoimmune gastritis (CAG). Although gNENs are not acknowledged as a typical entity in VHL patients, in the present case, gNENs were composed of neoplastic cells with clear cytoplasm usually seen in tumors related to VHL disease. We additionally performed a literature review on the presence of neuroendocrine clear cell tumors and report on further cases of clear cell NENs. The present case illustrates that clear-cell transformation in gNENs may be due to the dual genetic background of the patient; the real oncogenic stimulus may be more closely related to CAG than to VHL disease accompanied by an interplay between neoplastic and autoimmune processes. Therefore, close monitoring of patients with clear cell NENs appears to be important before excluding VHL disease, even in the context of phenotypically unrelated diseases.
    Language English
    Publishing date 2024-04-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2075912-5
    ISSN 2520-8721 ; 1109-3099
    ISSN (online) 2520-8721
    ISSN 1109-3099
    DOI 10.1007/s42000-024-00556-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Revealing Insights: A Comprehensive Overview of Gastric Outlet Obstruction Management, with Special Emphasis on EUS-Guided Gastroenterostomy.

    Ziogas, Dimitrios / Vasilakis, Thomas / Kapizioni, Christina / Koukoulioti, Eleni / Tziatzios, Georgios / Gkolfakis, Paraskevas / Facciorusso, Antonio / Papanikolaou, Ioannis S

    Medical sciences (Basel, Switzerland)

    2024  Volume 12, Issue 1

    Abstract: Gastric outlet obstruction (GOO) poses a common and challenging clinical scenario, characterized by mechanical blockage in the pylorus, distal stomach, or duodenum, resulting in symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its ... ...

    Abstract Gastric outlet obstruction (GOO) poses a common and challenging clinical scenario, characterized by mechanical blockage in the pylorus, distal stomach, or duodenum, resulting in symptoms such as nausea, vomiting, abdominal pain, and early satiety. Its diverse etiology encompasses both benign and malignant disorders. The spectrum of current treatment modalities extends from conservative approaches to more invasive interventions, incorporating procedures like surgical gastroenterostomy (SGE), self-expandable metallic stents (SEMSs) placement, and the advanced technique of endoscopic ultrasound-guided gastroenterostomy (EUS-GE). While surgery is favored for longer life expectancy, stents are preferred in malignant gastric outlet stenosis. The novel EUS-GE technique, employing a lumen-apposing self-expandable metal stent (LAMS), combines the immediate efficacy of stents with the enduring benefits of gastroenterostomy. Despite its promising outcomes, EUS-GE is a technically demanding procedure requiring specialized expertise and facilities.
    MeSH term(s) Humans ; Gastroenterostomy/adverse effects ; Gastroenterostomy/methods ; Endosonography/adverse effects ; Endosonography/methods ; Gastric Outlet Obstruction/diagnostic imaging ; Gastric Outlet Obstruction/etiology ; Gastric Outlet Obstruction/surgery ; Pylorus/surgery ; Stents/adverse effects ; Constriction, Pathologic/complications ; Constriction, Pathologic/surgery
    Language English
    Publishing date 2024-02-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2754473-4
    ISSN 2076-3271 ; 2076-3271
    ISSN (online) 2076-3271
    ISSN 2076-3271
    DOI 10.3390/medsci12010009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comment on: Association between Helicobacter pylori infection and incident risk of dementia: The AMI cohort.

    Kountouras, Jannis / Kazakos, Evangelos / Vardaka, Elisabeth / Mouratidou, Maria C / Kyrailidi, Foteini / Tzitiridou-Chatzopoulou, Maria / Orovou, Eirini / Papanikolaou, Ioannis S / Doulberis, Michael / Zavos, Christos

    Journal of the American Geriatrics Society

    2024  

    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Letter
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.18929
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ud II Zs.168: Show issues Location:
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  7. Article ; Online: Endoscopic Management of Difficult Biliary Stones: An Evergreen Issue.

    Manti, Magdalini / Shah, Jimil / Papaefthymiou, Apostolis / Facciorusso, Antonio / Ramai, Daryl / Tziatzios, Georgios / Papadopoulos, Vasilios / Paraskeva, Konstantina / Papanikolaou, Ioannis S / Triantafyllou, Konstantinos / Arvanitakis, Marianna / Archibugi, Livia / Vanella, Giuseppe / Hollenbach, Marcus / Gkolfakis, Paraskevas

    Medicina (Kaunas, Lithuania)

    2024  Volume 60, Issue 2

    Abstract: Choledocholithiasis is one of the most common indications for endoscopic retrograde cholangiopancreatography (ERCP) in daily practice. Although the majority of stones are small and can be easily removed in a single endoscopy session, approximately 10-15% ...

    Abstract Choledocholithiasis is one of the most common indications for endoscopic retrograde cholangiopancreatography (ERCP) in daily practice. Although the majority of stones are small and can be easily removed in a single endoscopy session, approximately 10-15% of patients have complex biliary stones, requiring additional procedures for an optimum clinical outcome. A plethora of endoscopic methods is available for the removal of difficult biliary stones, including papillary large balloon dilation, mechanical lithotripsy, and electrohydraulic and laser lithotripsy. In-depth knowledge of these techniques and the emerging literature on them is required to yield the most optimal therapeutic effects. This narrative review aims to describe the definition of difficult bile duct stones based on certain characteristics and streamline their endoscopic retrieval using various modalities to achieve higher clearance rates.
    MeSH term(s) Humans ; Treatment Outcome ; Cholangiopancreatography, Endoscopic Retrograde/methods ; Gallstones/surgery ; Catheterization/methods ; Choledocholithiasis/surgery
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina60020340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6270: Show issues Location:
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  8. Article: EUS-Guided Diagnosis of Gastric Subepithelial Lesions, What Is New?

    Vasilakis, Thomas / Ziogas, Dimitrios / Tziatzios, Georgios / Gkolfakis, Paraskevas / Koukoulioti, Eleni / Kapizioni, Christina / Triantafyllou, Konstantinos / Facciorusso, Antonio / Papanikolaou, Ioannis S

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: Gastric subepithelial lesions (SELs) are intramural lesions that arise underneath the gastric mucosa. SELs can be benign, but can also be malignant or have malignant potential. Therefore, correct diagnosis is crucial. Endosonography has been established ... ...

    Abstract Gastric subepithelial lesions (SELs) are intramural lesions that arise underneath the gastric mucosa. SELs can be benign, but can also be malignant or have malignant potential. Therefore, correct diagnosis is crucial. Endosonography has been established as the diagnostic gold standard. Although the identification of some of these lesions can be carried out immediately, solely based on their echo characteristics, for certain lesions histological examination is necessary. Sometimes histology can be inconclusive, especially for smaller lesions. Therefore, new methods have been developed in recent years to assist decision making, such as contrast enhanced endosonography, EUS elastography, and artificial intelligence systems. In this narrative review we provide a complete overview of the gastric SELs and summarize the new data of the last ten years concerning the diagnostic advances of endosonography on this topic.
    Language English
    Publishing date 2023-06-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13132176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Endoscopic ultrasound-guided tissue acquisition beyond the pancreas.

    Manthopoulou, Eleni / Ramai, Daryl / Ioannou, Alexandros / Gkolfakis, Paraskevas / Papanikolaou, Ioannis S / Mangiavillano, Benedetto / Triantafyllou, Konstantinos / Crinò, Stefano Francesco / Facciorusso, Antonio

    Annals of gastroenterology

    2023  Volume 36, Issue 3, Page(s) 257–266

    Abstract: Endoscopic ultrasound (EUS) offers the ability to obtain tissue material via a fine needle under direct visualization for cytological or pathological examination. Prior studies have looked at EUS tissue acquisition; however, most reports have been ... ...

    Abstract Endoscopic ultrasound (EUS) offers the ability to obtain tissue material via a fine needle under direct visualization for cytological or pathological examination. Prior studies have looked at EUS tissue acquisition; however, most reports have been centered around lesions of the pancreas. This paper aims to review the literature on EUS tissue acquisition in other organs (beyond the pancreas) such as the liver, biliary tree, lymph nodes, and upper and lower gastrointestinal tracts. Furthermore, techniques for obtaining tissue samples under EUS guidance continue to evolve. Specifically, some of the techniques that endoscopists employ are suction techniques (i.e., dry heparin, dry suction technique, wet suction technique), the slow pull technique, and the fanning technique. Apart from acquisition techniques, the type and size of the needle utilized play a major role in the quality of samples. This review describes the indications for tissue acquisition for each organ, and also describes and compares the various tissue acquisition techniques, as well as the different needles used according to their shape and size.
    Language English
    Publishing date 2023-04-08
    Publishing country Greece
    Document type Journal Article ; Review
    ZDB-ID 2032850-3
    ISSN 1108-7471
    ISSN 1108-7471
    DOI 10.20524/aog.2023.0797
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Prevalence of Small Intestinal Bacterial Overgrowth Syndrome in Patients with Non-Alcoholic Fatty Liver Disease/Non-Alcoholic Steatohepatitis: A Cross-Sectional Study.

    Gkolfakis, Paraskevas / Tziatzios, Georgios / Leite, Gabriela / Papanikolaou, Ioannis S / Xirouchakis, Elias / Panayiotides, Ioannis G / Karageorgos, Athanasios / Millan, Maria Jesus / Mathur, Ruchi / Weitsman, Stacy / Dimitriadis, George D / Giamarellos-Bourboulis, Evangelos J / Pimentel, Mark / Triantafyllou, Konstantinos

    Microorganisms

    2023  Volume 11, Issue 3

    Abstract: Introduction: Non-alcoholic fatty liver disease (NAFLD) is a multifactorial, wide-spectrum liver disorder. Small intestinal bacterial overgrowth (SIBO) is characterized by an increase in the number and/or type of colonic bacteria in the upper ... ...

    Abstract Introduction: Non-alcoholic fatty liver disease (NAFLD) is a multifactorial, wide-spectrum liver disorder. Small intestinal bacterial overgrowth (SIBO) is characterized by an increase in the number and/or type of colonic bacteria in the upper gastrointestinal tract. SIBO, through energy salvage and induction of inflammation, may be a pathophysiological factor for NAFLD development and progression.
    Aim/methods: Consecutive patients with histological, biochemical, or radiological diagnosis of any stage of NAFLD (non-alcoholic fatty liver [NAFL], non-alcoholic steatohepatitis [NASH], cirrhosis) underwent upper gastrointestinal endoscopy. Duodenal fluid (2cc) was aspirated from the 3rd-4th part of duodenum into sterile containers. SIBO was defined as ≥10
    Results: We enrolled 125 patients (51 NAFL, 27 NASH, 17 cirrhosis, and 30 HC) aged 54 ± 11.9 years and with a weight of 88.3 ± 19.6 kg (NAFLD vs. HC 90.7 ± 19.1 vs. 80.8 ± 19.6 kg,
    Conclusion: The prevalence of SIBO is significantly higher in a cohort of patients with NAFLD compared to healthy controls. Moreover, SIBO is more prevalent in patients with NASH-associated cirrhosis compared to patients with NAFL.
    Language English
    Publishing date 2023-03-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11030723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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