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  1. Article: Unusual Cause of Gastrointestinal Bleeding in a Patient with Turner Syndrome.

    D'Incao, Rafael Bergesch / Appel-da-Silva, Marcelo Campos / Marcon, Patricia Dos Santos / Correa, Eduardo Marques / Manenti, Euler / Corso, Carlos Otávio

    Case reports in gastroenterology

    2018  Volume 12, Issue 2, Page(s) 292–296

    Abstract: Turner syndrome is an exclusively female genetic disease caused by complete or partial absence of the second X chromosome. It is classically characterized by congenital lymphedema, short stature, and gonadal dysgenesis. In addition, the syndrome is ... ...

    Abstract Turner syndrome is an exclusively female genetic disease caused by complete or partial absence of the second X chromosome. It is classically characterized by congenital lymphedema, short stature, and gonadal dysgenesis. In addition, the syndrome is associated with several other abnormalities. One of them is gastrointestinal bleeding, which is frequently associated with inflammatory bowel disease, but it can also be caused by vascular lesions such as hemangioma, vascular ectasia, and telangiectasia. We report the case of a patient with Turner syndrome with an episode of gastrointestinal bleeding, outlining our pathway for the investigation and treatment of this condition.
    Language English
    Publishing date 2018-06-18
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000489300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Unusual Cause of Gastrointestinal Bleeding in a Patient with Turner Syndrome

    D’Incao, Rafael Bergesch / Appel-da-Silva, Marcelo Campos / Marcon, Patricia dos Santos / Correa, Eduardo Marques / Manenti, Euler / Corso, Carlos Otávio

    Case Reports in Gastroenterology

    2018  Volume 12, Issue 2, Page(s) 292–296

    Abstract: Turner syndrome is an exclusively female genetic disease caused by complete or partial absence of the second X chromosome. It is classically characterized by congenital lymphedema, short stature, and gonadal dysgenesis. In addition, the syndrome is ... ...

    Institution Department of Gastroenterology and Endoscopy, Hospital Mãe de Deus, Porto Alegre, Brazil
    Department of Cardiology, Hospital Mãe de Deus, Porto Alegre, Brazil
    Department of Surgery, Universidade Federal do Rio Grande do Sul and Hospital Mãe de Deus, Porto Alegre, Brazil
    Abstract Turner syndrome is an exclusively female genetic disease caused by complete or partial absence of the second X chromosome. It is classically characterized by congenital lymphedema, short stature, and gonadal dysgenesis. In addition, the syndrome is associated with several other abnormalities. One of them is gastrointestinal bleeding, which is frequently associated with inflammatory bowel disease, but it can also be caused by vascular lesions such as hemangioma, vascular ectasia, and telangiectasia. We report the case of a patient with Turner syndrome with an episode of gastrointestinal bleeding, outlining our pathway for the investigation and treatment of this condition.
    Keywords Turner syndrome ; Gastrointestinal bleeding ; Oral anticoagulants ; Small bowel
    Language English
    Publishing date 2018-06-18
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Single Case ; This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC).
    ZDB-ID 2440540-1
    ISSN 1662-0631 ; 1662-0631
    ISSN (online) 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000489300
    Database Karger publisher's database

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  3. Article ; Online: Adipokine Levels Versus Hepatic Histopathology in Bariatric Surgery Patients.

    D'Incao, Rafael Bergesch / Tovo, Cristiane Valle / Mattevi, Vanessa Suñé / Borges, Diego Olschowsky / Ulbrich, Jane Maria / Coral, Gabriela Perdomo / Ramos, Mauricio Jacques / Meinhardt, Nelson Guardiola

    Obesity surgery

    2017  Volume 27, Issue 8, Page(s) 2151–2158

    Abstract: Background: Obesity is a worldwide prevalent disease and is an underlying factor of non-alcoholic fatty liver disease (NAFLD). It has been understood as a chronic inflammatory state, being associated with the production of adipokines. The aim of this ... ...

    Abstract Background: Obesity is a worldwide prevalent disease and is an underlying factor of non-alcoholic fatty liver disease (NAFLD). It has been understood as a chronic inflammatory state, being associated with the production of adipokines. The aim of this study was to analyze the levels of adipokines in the serum, visceral, and subcutaneous fat and to compare them with hepatic histopathology in morbidly obese patients.
    Methods: This is a cross-sectional observational study, which analyzed the findings of liver biopsy in patients undergoing bariatric surgery and who had performed analysis of adipokines mRNA expression (adiponectin-ADIPOQ, leptin-LEP, and resistin-RETN) in subcutaneous and visceral adipose tissue and circulating adipokines in serum. Liver biopsies performed were evaluated according to Kleiner criteria.
    Results: The study analyzed 25 patients undergoing bariatric surgery. The sample was composed exclusively of women. There was a predominance of NAFLD, with 21 patients (84%) with intrahepatic fat accumulation. Twelve patients presented non-alcoholic steatohepatitis (NASH). Glycated hemoglobin levels (HbA1c) were elevated in NASH patients. ADIPOQ levels were directly correlated with high-density lipoprotein (HDL) cholesterol levels and inversely correlated with triglycerides and total cholesterol. LEP levels showed an inverse relationship with the degree of steatosis, and RETN levels showed an inverse relationship with fibrosis stages.
    Conclusion: Serum LEP levels were reduced in the presence of increased levels of intrahepatic fat, and serum levels of RETN were diminished in the presence of NASH. HbA1c levels were higher in the presence of NASH, indirectly reflecting insulin resistance. Moreover, ADIPOQ levels were related to blood lipid profile.
    MeSH term(s) Adipokines/blood ; Adult ; Bariatric Surgery ; Biopsy ; Cross-Sectional Studies ; Female ; Humans ; Intra-Abdominal Fat/chemistry ; Intra-Abdominal Fat/pathology ; Liver/chemistry ; Liver/pathology ; Middle Aged ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/pathology ; Obesity, Morbid/blood ; Obesity, Morbid/complications ; Obesity, Morbid/pathology ; Obesity, Morbid/surgery ; Subcutaneous Fat/chemistry ; Subcutaneous Fat/pathology
    Chemical Substances Adipokines
    Language English
    Publishing date 2017-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-017-2627-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3381: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Percutaneous liver biopsy--2 decades of experience in a public hospital in the South of Brazil.

    D'Incao, Rafael Bergesch / Silva, Marcelo Campos Appel da / Almeida, Paulo Roberto Lerias de / Renon, Viviane Plasse / Tovo, Cristiane Valle

    Annals of hepatology

    2013  Volume 12, Issue 6, Page(s) 876–880

    Abstract: Introduction: Liver biopsy is a complementary method for diagnosis, staging and therapeutic guidance in liver diseases, where chronic viral hepatitis are the most acknowledged causes for the indication of histopathological study. The objective is to ... ...

    Abstract Introduction: Liver biopsy is a complementary method for diagnosis, staging and therapeutic guidance in liver diseases, where chronic viral hepatitis are the most acknowledged causes for the indication of histopathological study. The objective is to assess the patients' profile as well as the indication and results of percutaneous liver biopsies in a tertiary hospital.
    Material and methods: A descriptive, cross-section study was carried out through the review of medical charts (retrospective cohort) of patients submitted to blind percutaneous liver biopsies (PLB) at a hospital in Porto Alegre, South Brazil, from October 1993 to December 2011.
    Results: 1,955 PLB were carried out, the mean patients' age was 44.8 years old, and 1,127 (57.65%) were men. Chronic hepatitis C was the main indication (60.5%), followed by HCV-HIV coinfection (12.2%) and chronic hepatitis B (3.5%). Seven cases (0.3%) had complications, without deaths.
    Conclusion: PLB is a safe method and continues to be an important option to assist patients with chronic liver disease.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Biopsy/adverse effects ; Biopsy/methods ; Brazil/epidemiology ; Coinfection ; Cross-Sectional Studies ; Female ; HIV Infections/epidemiology ; Hepatitis B, Chronic/epidemiology ; Hepatitis B, Chronic/pathology ; Hepatitis C, Chronic/epidemiology ; Hepatitis C, Chronic/pathology ; Hospitals, Public ; Humans ; Liver/pathology ; Liver/virology ; Male ; Middle Aged ; Predictive Value of Tests ; Prevalence ; Retrospective Studies ; Time Factors ; Young Adult
    Language English
    Publishing date 2013-11
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 2188733-0
    ISSN 1665-2681
    ISSN 1665-2681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6221: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Whipple's disease: rare disorder and late diagnosis.

    Renon, Viviane Plasse / Appel-da-Silva, Marcelo Campos / D'Incao, Rafael Bergesch / Lul, Rodrigo Mayer / Kirschnick, Luciana Schmidt / Galperim, Bruno

    Revista do Instituto de Medicina Tropical de Sao Paulo

    2012  Volume 54, Issue 5, Page(s) 293–297

    Abstract: Whipple's disease is a rare systemic infectious disorder caused by the bacterium Tropheryma whipplei. We report the case of a 61-year-old male patient who presented to emergency room complaining of asthenia, arthralgia, anorexia, articular complaints ... ...

    Abstract Whipple's disease is a rare systemic infectious disorder caused by the bacterium Tropheryma whipplei. We report the case of a 61-year-old male patient who presented to emergency room complaining of asthenia, arthralgia, anorexia, articular complaints intermittent diarrhea, and a 10-kg weight loss in one year. Laboratory tests showed the following results: Hb = 7.5 g/dL, albumin = 2.5 mg/dL, weight = 50.3 kg (BMI 17.4 kg/m²). Upper gastrointestinal endoscopy revealed areas of focal enanthema in the duodenum. An endoscopic biopsy was suggestive of Whipple's disease. Diagnosis was confirmed based on a positive serum polymerase chain reaction. Treatment was initiated with intravenous ceftriaxone followed by oral trimethoprim-sulfamethoxazole. After one year of treatment, the patient was asymptomatic, with Hb = 13.5 g/dL, serum albumin = 5.3 mg/dL, and weight = 70 kg (BMI 24.2 kg/m²). Whipple's disease should be considered a differential diagnosis in patients with prolonged constitutional and/or gastrointestinal symptoms. Appropriate antibiotic treatment improves the quality of life of patients.
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Ceftriaxone/therapeutic use ; Delayed Diagnosis ; Humans ; Male ; Middle Aged ; Rare Diseases/diagnosis ; Rare Diseases/drug therapy ; Treatment Outcome ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use ; Whipple Disease/diagnosis ; Whipple Disease/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Ceftriaxone (75J73V1629) ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2)
    Language English
    Publishing date 2012-09-14
    Publishing country Brazil
    Document type Case Reports ; Journal Article
    ZDB-ID 128928-7
    ISSN 1678-9946 ; 0036-4665
    ISSN (online) 1678-9946
    ISSN 0036-4665
    DOI 10.1590/s0036-46652012000500010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 292: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Percutaneous liver biopsy - 2 decades of experience in a public hospital in the South of Brazil

    Rafael Bergesch D’Incao / Marcelo Campos Appel da Silva / Paulo Roberto Lerias de Almeida / Viviane Plasse Renon / Cristiane Valle Tovo

    Annals of Hepatology, Vol 12, Iss 6, Pp 876-

    2013  Volume 880

    Abstract: Introduction. Liver biopsy is a complementary method for diagnosis, staging and therapeutic guidance in liver diseases, where chronic viral hepatitis are the most acknowledged causes for the indication of histopa-thological study. The objective is to ... ...

    Abstract Introduction. Liver biopsy is a complementary method for diagnosis, staging and therapeutic guidance in liver diseases, where chronic viral hepatitis are the most acknowledged causes for the indication of histopa-thological study. The objective is to assess the patients’ profile as well as the indication and results of percutaneous liver biopsies in a tertiary hospital.Material and methods. A descriptive, cross-section study was carried out through the review of medical charts (retrospective cohort) of patients submitted to blind percutaneous liver biopsies (PLB) at a hospital in Porto Alegre, South Brazil, from October 1993 to December 2011.Results. 1,955 PLB were carried out, the mean patients’ age was 44.8 years old, and 1,127 (57.65%) were men. Chronic hepatitis C was the main indication (60.5%), followed by HCV-HIV coinfection (12.2%) and chronic hepatitis B (3.5%). Seven cases (0.3%) had complications, without deaths.Conclusion. PLB is a safe method and continues to be an important option to assist patients with chronic liver disease.
    Keywords Liver biopsy ; Chronic hepatitis ; Hepatitis C ; Specialties of internal medicine ; RC581-951
    Subject code 610
    Language English
    Publishing date 2013-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Whipple's disease

    Viviane Plasse Renon / Marcelo Campos Appel-da-Silva / Rafael Bergesch D'Incao / Rodrigo Mayer Lul / Luciana Schmidt Kirschnick / Bruno Galperim

    Revista do Instituto de Medicina Tropical de São Paulo, Vol 54, Iss 5, Pp 293-

    rare disorder and late diagnosis

    2012  Volume 297

    Abstract: Whipple's disease is a rare systemic infectious disorder caused by the bacterium Tropheryma whipplei. We report the case of a 61-year-old male patient who presented to emergency room complaining of asthenia, arthralgia, anorexia, articular complaints ... ...

    Abstract Whipple's disease is a rare systemic infectious disorder caused by the bacterium Tropheryma whipplei. We report the case of a 61-year-old male patient who presented to emergency room complaining of asthenia, arthralgia, anorexia, articular complaints intermittent diarrhea, and a 10-kg weight loss in one year. Laboratory tests showed the following results: Hb = 7.5 g/dL, albumin = 2.5 mg/dL, weight = 50.3 kg (BMI 17.4 kg/m²). Upper gastrointestinal endoscopy revealed areas of focal enanthema in the duodenum. An endoscopic biopsy was suggestive of Whipple's disease. Diagnosis was confirmed based on a positive serum polymerase chain reaction. Treatment was initiated with intravenous ceftriaxone followed by oral trimethoprim-sulfamethoxazole. After one year of treatment, the patient was asymptomatic, with Hb = 13.5 g/dL, serum albumin = 5.3 mg/dL, and weight = 70 kg (BMI 24.2 kg/m²). Whipple's disease should be considered a differential diagnosis in patients with prolonged constitutional and/or gastrointestinal symptoms. Appropriate antibiotic treatment improves the quality of life of patients.
    Keywords Whipple's disease ; Tropheryma whipplei ; Malabsorption syndromes ; Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2012-10-01T00:00:00Z
    Publisher Universidade de São Paulo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

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