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  1. Article: Antimalarial constituents of Chinese drug, ch'ang shan, Dichroa febrifuga Lour.

    CHOU, T Q / FU, F Y / KAO, Y S

    Journal of the American Chemical Society

    2008  Volume 70, Issue 5, Page(s) 1765–1767

    MeSH term(s) Antimalarials ; Humans
    Chemical Substances Antimalarials
    Language English
    Publishing date 2008-07-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/ja01185a028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online ; E-Book: Microbial Cyclic Di-Nucleotide Signaling

    Chou, Shan-Ho / Guiliani, Nicolas / Lee, Vincent T. / Römling, Ute

    2020  

    Abstract: This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of ... ...

    Author's details edited by Shan-Ho Chou, Nicolas Guiliani, Vincent T. Lee, Ute Römling
    Abstract This book explores the broad and diverse biological and physiological impacts of established and newly discovered cyclic di-nucleotide second messenger signaling systems, while also providing descriptions of the intriguing biochemical characteristics of multiple turnover enzymes and receptors. The respective chapters discuss the commonalities and diversity of cyclic di-GMP, cyclic di-AMP and recently discovered cyclic GMP-AMP signaling systems in manifold Gram-negative and Gram-positive bacteria. The global human pathogens Mycobacterium tuberculosis, Vibrio cholerae, Salmonella typhimurium, Escherichia coli and Streptococcus pneumoniae, the facultative human pathogen Pseudomonas aeruginosa, global plant pathogens as exemplified by Xanthomonas campestris and Burkholderia spp., and the omnipresent probiotic Lactobacilli, as well as environmentally important photoautotrophic cyanobacteria, the multicellular Myxococcus xanthus, and chemolithotrophic Acidithiobacillus are among the representatives of the microbial kingdom that are described. In turn, the various aspects of bacterial physiology affected by these signaling systems– e.g. biofilm formation and dispersal, the cell cycle, motility, virulence, production of antimicrobials, fundamental metabolism and osmohomeostasis – are discussed in detail in the context of different microorganisms. Dedicated chapters focus on the population diversity of cyclic dinucleotide signaling systems, their tendency to be horizontally transferred, the cyclic di-GMP signaling system in the social amoeba Dictyostelium, honorary cyclic (di)nucleotides, and the development of strategies for interfering with cyclic dinucleotide signaling in order to manipulate microbial behavior. Taken together, the chapters provide an authoritative source of information for a broad readership: beginners and advanced researchers from various disciplines; individuals seeking a broad overview of cyclic di-nucleotide signaling; and those who want to learn more about specific aspects. Also featuring reviews with a forward-looking perspective, the book offers a valuable source of inspiration for future research directions.
    Keywords Bacteriology ; Nucleic acids ; Proteins  ; Medical microbiology ; Nucleic Acid Chemistry ; Receptors ; Medical Microbiology
    Subject code 574.87328
    Language English
    Size 1 online resource (XVIII, 657 p. 108 illus., 96 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-33308-6 ; 3-030-33307-8 ; 978-3-030-33308-9 ; 978-3-030-33307-2
    DOI 10.1007/978-3-030-33308-9
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article: The evaluation of reno- and hepatoprotective effects of huai-shan-yao (Rhizome Dioscoreae).

    Lee, Shih-Chang / Tsai, Chin-Chun / Chen, Jung-Chou / Lin, Chun-Ching / Hu, Miao-Lin / Lu, Shin

    The American journal of Chinese medicine

    2002  Volume 30, Issue 4, Page(s) 609–616

    Abstract: Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study ... we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries ... that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well ...

    Abstract Huai-shan-yao (Chinese yam; Rhizome Dioscoreae) is a common food in China. In the present study, we evaluated the protective effects of the crude extract of huai-shan-yao on acute kidney and liver injuries in rats induced by ethanol. Results of pharmacological, biochemical and pathologic observations all showed that rats treated with the extract of huai-shan-yao had decreased damage in renal tubules as well as decreased inflammation in the central vein and necrosis in the liver tissue.
    MeSH term(s) Animals ; Antioxidants/pharmacology ; Central Nervous System Depressants/toxicity ; Dioscorea/chemistry ; Drugs, Chinese Herbal/pharmacology ; Ethanol/toxicity ; Kidney/pathology ; Kidney Diseases/chemically induced ; Kidney Diseases/pathology ; Kidney Diseases/prevention & control ; Kidney Function Tests ; Liver/pathology ; Liver Diseases, Alcoholic/pathology ; Liver Diseases, Alcoholic/prevention & control ; Liver Function Tests ; Male ; Plant Extracts/pharmacology ; Plant Roots/chemistry ; Rats ; Rats, Wistar ; Silymarin/pharmacology
    Chemical Substances Antioxidants ; Central Nervous System Depressants ; Drugs, Chinese Herbal ; Plant Extracts ; Silymarin ; huai-shan-yao ; Ethanol (3K9958V90M)
    Language English
    Publishing date 2002
    Publishing country Singapore
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 193085-0
    ISSN 0192-415X ; 0090-2942
    ISSN 0192-415X ; 0090-2942
    DOI 10.1142/S0192415X02000624
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The relationship of air pollution to the prevalence of allergic diseases in Taichung and Chu-Shan in 2002.

    Yu, Jui Huan / Lue, Ko Huang / Lu, Ko Hsiu / Sun, Hai Lun / Lin, Yun Hsiang / Chou, Ming Chih

    Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi

    2005  Volume 38, Issue 2, Page(s) 123–126

    Abstract: ... the varying prevalence of allergic diseases in the city of Taichung and the rural town of Chu-Shan. We used ... questionnaires to screen children aged from 7 to 15 years in Taichung and Chu-Shan and compared the results ... and 2621 children in Chu-Shan. In Taichung, the prevalence of asthma was 7.0%, of allergic rhinitis 27 ...

    Abstract This study was conducted in order to determine the relationship between air pollution and the varying prevalence of allergic diseases in the city of Taichung and the rural town of Chu-Shan. We used questionnaires to screen children aged from 7 to 15 years in Taichung and Chu-Shan and compared the results from these 2 areas with the factors related to air pollution. The study included 11,580 children in Taichung and 2621 children in Chu-Shan. In Taichung, the prevalence of asthma was 7.0%, of allergic rhinitis 27.6% and of atopic dermatitis 3.4%. In Chu-Shan, the prevalence of asthma was 5.6%, of allergic rhinitis 21.8% and of atopic dermatitis 3.3%. We also collected data on the concentration of air pollutants in the 2 areas over a 1-year period from January to December 2001 and compared the average annual concentrations of various pollutants. Compared with Chu-Shan, Taichung had higher air concentrations of nitric oxide (NO; 11.47 +/- 4.75 vs 5.07 +/- 2.81 ppb), carbon monoxide (CO; 0.78 +/- 0.19 vs 0.59 +/- 0.12 ppm), nitrogen dioxide (NO(2); 24.99 +/- 6.8 vs 21.45 +/- 7.87 ppb) and sulfur dioxide (SO(2); 2.58 +/- 1.0 vs 2.44 +/- 0.88 ppb). Student's t test results showed that CO and NO were related significantly to the prevalence of allergic disease (p<0.005). The prevalence of both asthma and allergic rhinitis is higher in Taichung than in Chu-Shan, a finding that could be related to higher levels of some air pollutants in the urban location.
    MeSH term(s) Adolescent ; Air Pollution ; Asthma/epidemiology ; Carbon Monoxide/analysis ; Child ; Dermatitis, Atopic/epidemiology ; Female ; Humans ; Hypersensitivity/epidemiology ; Male ; Nitric Oxide/analysis ; Nitrogen Dioxide/analysis ; Prevalence ; Rhinitis, Allergic, Perennial/epidemiology ; Risk Factors ; Rural Health ; Sulfur Dioxide/analysis ; Taiwan/epidemiology ; Urban Health
    Chemical Substances Sulfur Dioxide (0UZA3422Q4) ; Nitric Oxide (31C4KY9ESH) ; Carbon Monoxide (7U1EE4V452) ; Nitrogen Dioxide (S7G510RUBH)
    Language English
    Publishing date 2005-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1497590-7
    ISSN 1684-1182 ; 0253-2662
    ISSN 1684-1182 ; 0253-2662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Chung-kuo kao shan hua hui

    Lang, Kaiyong / Feng, Chih-chou / Li, Po-sheng

    1997  

    Title variant Alpine flowering plants in China
    Institution Yün-nan sheng lin yeh kʻo hsüeh yüan
    Author's details [chu pien] Lang Kʻai-yung ; [fu chu pien] Feng Chih-chou, Li Po-sheng ; Yün-nan sheng lin yeh kʻo hsüeh yüan pien = Alpine flowering plants in China / [chief editor] Lang Kaiyong ; [deputy chief editor] Feng Zhizhou, Li Bosheng ; compiled by the Yunnan Academy of Forestry Science
    Keywords Mountain plants
    Language Chinese ; English ; Latin
    Size 154 p. :, chiefly col. ill. ;, 27 cm.
    Edition Ti 1 pan.
    Publisher Chung-kuo shih chieh yü chʻu pan she ; Chung-kuo kuo chi tʻu shu mao i tsung kung ssu (kuo chi shu tien) fa hsing
    Publishing place Pei-ching
    Document type Book
    Note In Chinese and English; nomenclature also in Latin. ; Includes index.
    ISBN 7505203231 ; 9787505203235
    Database NAL-Catalogue (AGRICOLA)

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  6. Book: Huan shan gao xiao yi yang zhi ji shu

    Chou, Pin / Hsueh, Chen-yu

    2000  

    Title variant Huanshan gaoxiaoyi yangzhi jishu
    Author's details Zhou Biyun, Xue Zhenyu bian zhu
    Keywords Eels.
    Language Chinese
    Size 6, 118 p. :, ill. ;, 19 cm.
    Edition Di 1 ban.
    Publisher Jin dun chu ban she
    Publishing place Beijing
    Document type Book
    ISBN 7508207297 ; 9787508207292
    Database NAL-Catalogue (AGRICOLA)

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  7. Book: Shan mu lin ti fu yü chien fa

    Chiang, Chih-lin / Yeh, Ching-chung / Chou, Pen-lin

    1982  

    Title translation Nurturing fir forest and interval cutting.
    Author's details Chiang Chih-lin, Yeh Ching-chung, Chou Pen-lin pien chu. --
    Keywords China fir.
    Language Chinese
    Size 5, 2, 110 p. :, ill. ;, 19 cm.
    Edition Ti 1 pan. --
    Publisher Chung-kuo lin yeh ch'u pan she
    Publishing place Pei-ching
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  8. Book: Tsen yang ts'ai p'ei shan mu

    Chou, Kuo-lin

    1981  

    Title translation How to cultivate pine wood.
    Author's details Chou Kuo Lin pien hsieh. --
    Keywords Pine
    Language Chinese
    Size 2, 55 p. :, ill. ;, 19 cm.
    Edition Tsai pan. --
    Publisher Hu-nan k'o hsüeh chi shu ch'u pan she
    Publishing place Chiang-sha
    Document type Book
    Database NAL-Catalogue (AGRICOLA)

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  9. Article: The quantitative analysis of subtropic forests in Hwang-shan

    Chou, C.L / Han, Y.L

    Chih wu Hsueh pao. = Acta botanica sinica. Dec 1979. v. 21 (4)

    1979  

    Title variant Quantitative analysis of subtropic forests in Hwang-shan [Anhui]
    Keywords China
    Language Chinese
    Dates of publication 1979-12
    Size p. 352-361., ill.
    Document type Article
    Note In Chinese; Summary in English. ; Title in original language could not be transcribed.
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Sequence Conservation, Domain Architectures, and Phylogenetic Distribution of the HD-GYP Type c-di-GMP Phosphodiesterases.

    Galperin, Michael Y / Chou, Shan-Ho

    Journal of bacteriology

    2021  Volume 204, Issue 4, Page(s) e0056121

    Abstract: The HD-GYP domain, named after two of its conserved sequence motifs, was first described in 1999 as a specialized version of the widespread HD phosphohydrolase domain that had additional highly conserved amino acid residues. Domain associations of HD-GYP ...

    Abstract The HD-GYP domain, named after two of its conserved sequence motifs, was first described in 1999 as a specialized version of the widespread HD phosphohydrolase domain that had additional highly conserved amino acid residues. Domain associations of HD-GYP indicated its involvement in bacterial signal transduction and distribution patterns of this domain suggested that it could serve as a hydrolase of the bacterial second messenger c-di-GMP, in addition to or instead of the EAL domain. Subsequent studies confirmed the ability of various HD-GYP domains to hydrolyze c-di-GMP to linear pGpG and/or GMP. Certain HD-GYP-containing proteins hydrolyze another second messenger, cGAMP, and some HD-GYP domains participate in regulatory protein-protein interactions. The recently solved structures of HD-GYP domains from four distinct organisms clarified the mechanisms of c-di-GMP binding and metal-assisted hydrolysis. However, the HD-GYP domain is poorly represented in public domain databases, which causes certain confusion about its phylogenetic distribution, functions, and domain architectures. Here, we present a refined sequence model for the HD-GYP domain and describe the roles of its most conserved residues in metal and/or substrate binding. We also calculate the numbers of HD-GYPs encoded in various genomes and list the most common domain combinations involving HD-GYP, such as the RpfG (REC-HD-GYP), Bd1817 (DUF3391-HD-GYP), and PmGH (GAF-HD-GYP) protein families. We also provide the descriptions of six HD-GYP-associated domains, including four novel integral membrane sensor domains. This work is expected to stimulate studies of diverse HD-GYP-containing proteins, their N-terminal sensor domains and the signals to which they respond.
    MeSH term(s) Bacterial Proteins/metabolism ; Cyclic GMP/analogs & derivatives ; Cyclic GMP/metabolism ; Phosphoric Diester Hydrolases/metabolism ; Phylogeny
    Chemical Substances Bacterial Proteins ; bis(3',5')-cyclic diguanylic acid (61093-23-0) ; Phosphoric Diester Hydrolases (EC 3.1.4.-) ; Cyclic GMP (H2D2X058MU)
    Language English
    Publishing date 2021-12-20
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2968-3
    ISSN 1098-5530 ; 0021-9193
    ISSN (online) 1098-5530
    ISSN 0021-9193
    DOI 10.1128/jb.00561-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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