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Article ; Online: Gas in the myocardium: a fatal presentation of

Khan, Hafiz Muhammad Waqas / Yousaf, Amman / Ahmad, Muhammad / Changezi, Hameem U

European heart journal. Case reports

2023 Volume 7, Issue 1, Page(s) ytac488

Abstract: Background: Clostridium perfringens: Case summary: A 52-year-old male presented to the emergency department with chest pain and exertional dyspnoea for three days. The patient was haemodynamically stable initially, and the physical examination was ... ...

Abstract	Background: Clostridium perfringens Case summary: A 52-year-old male presented to the emergency department with chest pain and exertional dyspnoea for three days. The patient was haemodynamically stable initially, and the physical examination was unremarkable. Initial laboratory workup revealed elevated D-dimer and troponin levels. Computerized tomography (CT) of the chest was negative for pulmonary embolism but showed a hypodense focus in the cardiac silhouette. Acute coronary syndrome protocol was initiated; however, invasive cardiac workup was negative. The patient had rapid clinical deterioration with development of respiratory failure, shock, and multiorgan failure within 24 h. A transesophageal echocardiogram demonstrated an abnormal echogenic focus, corresponding to CT chest area. Despite aggressive treatment, the patient passed away within 36 h. Later, the patient's blood culture grew Discussion: Unlike other reported cases of
Language	English
Publishing date	2023-01-02
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytac488
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Article: Mycobacterium chimaera

Ahmad, Muhammad / Yousaf, Amman / Khan, Hafiz Muhammad Waqas / Munir, Ahmad / Chandran, Arul

Proceedings (Baylor University. Medical Center)

2022 Volume 35, Issue 6, Page(s) 817–819

Abstract: Mycobacterium ... ...

Abstract	Mycobacterium chimaera
Language	English
Publishing date	2022-07-11
Publishing country	United States
Document type	Case Reports
ZDB-ID	2703932-8
ISSN	1525-3252 ; 0899-8280
ISSN (online)	1525-3252
ISSN	0899-8280
DOI	10.1080/08998280.2022.2095894
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Article: Feasibility Study of Anaerobic Baffled Reactor Coupled with Anaerobic Filter Followed by Membrane Filtration for Wastewater Treatment.

Khan, Aamir / Khan, Sher Jamal / Miran, Waheed / Zaman, Waqas Qamar / Aslam, Alia / Shahzad, Hafiz Muhammad Aamir

Membranes

2023 Volume 13, Issue 1

Abstract: The performance of a Decentralized Wastewater Treatment System (DWTS) comprising an Anaerobic Baffled Reactor (ABR) and an Anaerobic Filter (AF) and Membrane Filtration (MF) module was studied for domestic wastewater treatment. The efficiency of the ... ...

Abstract	The performance of a Decentralized Wastewater Treatment System (DWTS) comprising an Anaerobic Baffled Reactor (ABR) and an Anaerobic Filter (AF) and Membrane Filtration (MF) module was studied for domestic wastewater treatment. The efficiency of the system was evaluated by running ABR at four different HRTs (14, 12, 10, and 8 h) resulting in COD removal efficiencies of 74, 72, 69, and 65%, respectively. The performance of AF using four different filtration media, i.e., PVC pipe (25 mm), PVC pipe (20 mm), PVC pipe (15 mm), and Kaldnes K3, was determined at optimized HRT (12 h). Among all the filtration media tested, the highest performance efficiency of the system was found with the PVC pipe (20 mm), which showed COD, TP, and TKN removal of 79, 32, and 63%, respectively. The efficacy of the system was proven via significant COD and turbidity removal of 94.6 and 87.2%, respectively, by the combined system.
Language	English
Publishing date	2023-01-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2614641-1
ISSN	2077-0375
ISSN	2077-0375
DOI	10.3390/membranes13010079
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Article ; Online: Heart in a shell-a cascade of classical findings: a case report.

Khan, Hafiz Muhammad Waqas / Munir, Ahmad / Sud, Anup / Moza, Ankush

European heart journal. Case reports

2022 Volume 6, Issue 6, Page(s) ytac231

Abstract: Background: Idiopathic chronic constrictive pericarditis (CP) is an uncommon yet very important clinical entity as prompt diagnosis and early treatment are affiliated with improved outcomes. We describe an uncommon case of CP with a series of textbook ... ...

Abstract	Background: Idiopathic chronic constrictive pericarditis (CP) is an uncommon yet very important clinical entity as prompt diagnosis and early treatment are affiliated with improved outcomes. We describe an uncommon case of CP with a series of textbook findings and received successful treatment with surgical pericardiectomy (SP). Case summary: A 58-year-old male presented to the emergency department with exertional dyspnoea and anasarca. The past medical history was negative for infections like tuberculosis, viral, etc., connective tissue disease, prior cardiac surgery, human immunodeficiency virus, or any radiation therapy. The vital signs were within normal limits except mild hypoxia while the physical examination was consistent with congestive heart failure. Further investigations with laboratory testing, imaging with chest X-ray, computed tomography, echocardiogram, and invasive study with right heart catheterization were all consistent with idiopathic chronic CP. The patient underwent successful SP with significant improvement in clinical condition. Discussion: This case highlights the classical signs and symptoms along with important diagnostic features of CP. It is uncommon to see all the classical features of CP in one patient as described in the above case. Familiarity with these findings is crucial to make the diagnosis as early treatment is affiliated with improved outcomes.
Language	English
Publishing date	2022-06-10
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytac231
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Article: Exploring the Impact of Salicylic Acid and Farmyard Manure on Soil Rhizospheric Properties and Cadmium Stress Alleviation in Maize (

Ali, Hafiz Haider / Shehzadi, Nimra / Zaheer, Muhammad Saqlain / Seleiman, Mahmoud F / Aldhuwaib, Khalid J / Din Khan, Waqas Ud / Raza, Ali

Plants (Basel, Switzerland)

2023 Volume 12, Issue 17

Abstract: Cadmium (Cd) pollution is a growing environmental problem that negatively impacts plant growth and development, particularly in maize. In this research, the impact of farmyard manure (FYM) and salicylic acid (SA) on rhizospheric characteristics and the ... ...

Abstract	Cadmium (Cd) pollution is a growing environmental problem that negatively impacts plant growth and development, particularly in maize. In this research, the impact of farmyard manure (FYM) and salicylic acid (SA) on rhizospheric characteristics and the reduction of Cd stress in maize was examined at Government College (GC) University, Lahore, in 2022. The experiment was arranged with a randomized design, including three replications of 12 treatments (T
Language	English
Publishing date	2023-08-30
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704341-1
ISSN	2223-7747
ISSN	2223-7747
DOI	10.3390/plants12173115
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Article ; Online: Triazolothiadiazoles and triazolothiadiazines as potent α-glucosidase inhibitors: Mechanistic insights from kinetics studies, molecular docking and dynamics simulations.

Ullah, Saeed / Waqas, Muhammad / Halim, Sobia Ahsan / Khan, Imtiaz / Khalid, Asaad / Abdalla, Ashraf N / Makeen, Hafiz A / Ibrar, Aliya / Khan, Ajmal / Al-Harrasi, Ahmed

International journal of biological macromolecules

2023 Volume 250, Page(s) 126227

Abstract: Diabetes mellitus has been considered as a serious health problem worldwide due its high prevalence rate and associated complications. In this context, the current research work aims at exploring new structural leads for the treatment of a major ... ...

Abstract	Diabetes mellitus has been considered as a serious health problem worldwide due its high prevalence rate and associated complications. In this context, the current research work aims at exploring new structural leads for the treatment of a major metabolic disorder, diabetes mellitus type 2. The outcomes of our prior studies on a diverse set of triazolothiadiazole and triazolothiadiazine derivatives and their therapeutic potential, encouraged us to explore their anti-diabetic competency by targeting the key carbohydrate catabolic enzyme, α-glucosidase. Therefore, all these analogues were examined to reveal their contribution towards this severe metabolic issue. Interestingly, all the tested compounds (2a-2l and 3a-3p) exhibited several times more potent α-glucosidase inhibitory activities (IC
Language	English
Publishing date	2023-08-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.126227
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Article ; Online: Decoding the mystery of MMTV-like virus and its relationship with breast cancer metastasis.

Khalid, Hafiz Fawad / Bibi, Sadia / Ali, Amjad / Fawad, Nida / Shams, Muhammad Usman / Idrees, Wafa / Waqas, Muhammad / Rafique, Shazia / Khan, Abbas / Khan, Faizullah / Almajhdi, Fahad Nasser

Journal of infection and public health

2023 Volume 16, Issue 9, Page(s) 1396–1402

Abstract: Background: MMTV causes mammary tumors in mice, and it is associated with invasive and aggressive forms of breast cancer in humans. However, the underlying mechanisms are yet unknown. We aimed to determine the MMTV-like virus (MMTV-LV) association with ... ...

Abstract	Background: MMTV causes mammary tumors in mice, and it is associated with invasive and aggressive forms of breast cancer in humans. However, the underlying mechanisms are yet unknown. We aimed to determine the MMTV-like virus (MMTV-LV) association with histological types of breast cancer, nodal involvement, and metastasis. Methods: First, 105 breast cancer biopsies and 15 disease-free biopsies were collected. Details of clinicopathological characteristics were retrieved from patients' records. The status of MMTV-LV was already known for these biopsy samples. Associations of MMTV-LV prevalence with LNM status and metastatic history were determined. Next, quantitative PCR (qPCR) was used to quantify env gene mRNA in biopsies positive for MMTV-LV. Expression of the env gene was compared against different histopathological types of mammary tumor, LNM status, and metastasis by performing Ordinary One Way ANOVA followed by Tukey's multiple comparisons test. Results: MMTV-LV prevalence was found to have no significant association with LNM or metastatic history. As compared to normal control, expression of the env gene was significantly higher (>2.8 folds) in invasive samples (P-value: < 0.01). Expression was also higher (3.28 and 2.89 folds) in patient samples with LNM (P-value: 0.0006) or metastatic history (P-value: < 0.0001), respectively. Conclusion: We conclude that MMTV-LV prevalence is not associated with LNM status or breast cancer metastasis; samples with invasive phenotypes, nodal involvement, and metastasis exhibit significantly higher expression of the MMTV-like env gene.
MeSH term(s)	Mammary Tumor Virus, Mouse/genetics ; Breast Neoplasms/virology ; Neoplasm Metastasis/pathology ; Female ; Animals ; Mice ; Prevalence ; Polymerase Chain Reaction ; Genes, env/genetics
Language	English
Publishing date	2023-07-14
Publishing country	England
Document type	Journal Article
ZDB-ID	2467587-8
ISSN	1876-035X ; 1876-0341
ISSN (online)	1876-035X
ISSN	1876-0341
DOI	10.1016/j.jiph.2023.07.004
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Article: The Synergistic Relationship Between Atrial Fibrillation and Diabetes Mellitus: Implications for Cardiovascular and Metabolic Health.

Mohsin, Maryam / Zeyad, Hafiz / Khalid, Hareem / Gapizov, Abubakar / Bibi, Ruqiya / Kamani, Yashkumar Girdharlal / Rashid, Ahmed / Shams, Muhammad / Khalid, Faizan / Khan, Syeda / Waqas, Muhammad / Ishfaq, Anzal / Kebede, Ayele H / Subhan, Muhammad

Cureus

2023 Volume 15, Issue 9, Page(s) e45881

Abstract: Type 2 diabetes mellitus (T2DM) and atrial fibrillation (AF) are widespread chronic conditions that profoundly impact public health. While the intricate mechanisms linking these two diseases remain incompletely understood, this review sets out to ... ...

Abstract	Type 2 diabetes mellitus (T2DM) and atrial fibrillation (AF) are widespread chronic conditions that profoundly impact public health. While the intricate mechanisms linking these two diseases remain incompletely understood, this review sets out to comprehensively analyze the current evidence about their pathophysiology, epidemiology, diagnosis, prognosis, and treatment. We reveal that T2DM can influence the electrical and structural properties of the atria through multiple pathways, including oxidative stress, inflammation, fibrosis, connexin remodeling, glycemic variability, and autonomic dysfunction. Moreover, it significantly influences AF's clinical course, elevating the risk of heart failure, stroke, and cardiovascular mortality. Our review also explores treatment options for individuals with T2DM and AF, encompassing antidiabetic and antiarrhythmic drugs and non-pharmacological interventions, such as cardioversion catheter ablation and direct current cardioversion. This review depicts an insight into the clinical interplay between T2DM and AF. It deepens our comprehension of the fundamental mechanisms, potential therapeutic interventions, and their implications for patient care. This comprehensive resource benefits researchers seeking to deepen their knowledge in this domain. Ultimately, our findings pave the way for more effective strategies in managing AF within the context of T2DM.
Language	English
Publishing date	2023-09-24
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.45881
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Article ; Online: Biochar and nano biochar: Enhancing salt resilience in plants and soil while mitigating greenhouse gas emissions: A comprehensive review.

Sultan, Haider / Li, Yusheng / Ahmed, Waqas / Yixue, Mu / Shah, Asad / Faizan, Mohammad / Ahmad, Aqeel / Abbas, Hafiz Muhammad Mazhar / Nie, Lixiao / Khan, Mohammad Nauman

Journal of environmental management

2024 Volume 355, Page(s) 120448

Abstract: Salinity stress poses a significant challenge to agriculture, impacting soil health, plant growth and contributing to greenhouse gas (GHG) emissions. In response to these intertwined challenges, the use of biochar and its nanoscale counterpart, nano- ... ...

Abstract	Salinity stress poses a significant challenge to agriculture, impacting soil health, plant growth and contributing to greenhouse gas (GHG) emissions. In response to these intertwined challenges, the use of biochar and its nanoscale counterpart, nano-biochar, has gained increasing attention. This comprehensive review explores the heterogeneous role of biochar and nano-biochar in enhancing salt resilience in plants and soil while concurrently mitigating GHG emissions. The review discusses the effects of these amendments on soil physicochemical properties, improved water and nutrient uptake, reduced oxidative damage, enhanced growth and the alternation of soil microbial communities, enhance soil fertility and resilience. Furthermore, it examines their impact on plant growth, ion homeostasis, osmotic adjustment and plant stress tolerance, promoting plant development under salinity stress conditions. Emphasis is placed on the potential of biochar and nano-biochar to influence soil microbial activities, leading to altered emissions of GHG emissions, particularly nitrous oxide(N
MeSH term(s)	Greenhouse Gases/analysis ; Soil/chemistry ; Resilience, Psychological ; Charcoal/chemistry ; Agriculture ; Sodium Chloride ; Methane/analysis ; Nitrous Oxide/analysis ; Carbon Dioxide/analysis
Chemical Substances	biochar ; Greenhouse Gases ; Soil ; Charcoal (16291-96-6) ; Sodium Chloride (451W47IQ8X) ; Methane (OP0UW79H66) ; Nitrous Oxide (K50XQU1029) ; Carbon Dioxide (142M471B3J)
Language	English
Publishing date	2024-02-28
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2024.120448
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Article ; Online: Evaluation of Rhizospheric-Pseudomonas spp. for the management of Meloidogyne incognita in tomato

Nadeem Ahmed / Hamed A. Ghramh / Qaiser Shakeel / Waqas Ashraf / Hafiz Tassawar Abbas / Rana Binyamin / Ashir Masroor / Muhammad Raheel / Zulqurnain Khan

Journal of King Saud University: Science, Vol 35, Iss 1, Pp 102395- (2023)

1480

Abstract: Root knot nematodes are commercially important plant parasites of many vegetable crops in Pakistan. This study investigate antagonistic effect of Pseudomonas spp. against M. incognita on tomato crop. Ten tomato cultivars were screened against RKN ... ...

Abstract	Root knot nematodes are commercially important plant parasites of many vegetable crops in Pakistan. This study investigate antagonistic effect of Pseudomonas spp. against M. incognita on tomato crop. Ten tomato cultivars were screened against RKN infection. Roma was found the most resistant against infection of M. incognita while money maker was found the most susceptible. Gall or egg mass number/indices are more resistant to RKN. Pseudomonas strains inoculated in the infected tomato plants reduced galling index and also improved the growth of the plant. So, it was obvious that bio-control agents also act as PGPR by stimulating plant growth and inducing resistance through the increase of total phenolic contents and salicylic acid. Tomato cv. Roma showed the greatest increase of total phenol contents and salicylic acid exhibiting tolerance against M. incognita infestation. Tomato cv. Roma showed significantly resistant response against root-knot nematode diseases. Pseudomonas showed significant antagonistic potential against M. incognita in tomato plant.
Keywords	Nematode ; M. incognita ; RKN ; Pseudomonas spp ; Biochemical Properties ; Science (General) ; Q1-390
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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