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Article: Forward neutral pion production in p + p and d + Au collisions at square root sNN=200 GeV.

Adams, J / Aggarwal, M M / Ahammed, Z / Amonett, J / Anderson, B D / Arkhipkin, D / Averichev, G S / Badyal, S K / Bai, Y / Balewski, J / Barannikova, O / Barnby, L S / Baudot, J / Bekele, S / Belaga, V V / Bellingeri-Laurikainen, A / Bellwied, R / Berger, J / Bezverkhny, B I /

Bharadwaj, S / Bhasin, A / Bhati, A K / Bhatia, V S / Bichsel, H / Bielcik, J / Bielcikova, J / Billmeier, A / Bland, L C / Blyth, C O / Blyth, S-L / Bonner, B E / Botje, M / Boucham, A / Bouchet, J / Brandin, A V / Bravar, A / Bystersky, M / Cadman, R V / Cai, X Z / Caines, H / Sánchez, M Calderón de la Barca / Catu, O / Cebra, D / Chajecki, Z / Chaloupka, P / Chattopadhyay, S / Chen, H F / Chen, J H / Chen, Y / Cheng, J / Cherney, M / Chikanian, A / Choi, H A / Christie, W / Coffin, J P / Cormier, T M / Cosentino, M R / Cramer, J G / Crawford, H J / Das, D / Das, S / Daugherity, M / de Moura, M M / Dedovich, T G / Dephillips, M / Derevschikov, A A / Didenko, L / Dietel, T / Dogra, S M / Dong, W J / Dong, X / Draper, J E / Du, F / Dubey, A K / Dunin, V B / Dunlop, J C / Mazumdar, M R Dutta / Eckardt, V / Edwards, W R / Efimov, L G / Emelianov, V / Engelage, J / Eppley, G / Erazmus, B / Estienne, M / Fachini, P / Faivre, J / Fatemi, R / Fedorisin, J / Filimonov, K / Filip, P / Finch, E / Fine, V / Fisyak, Y / Fornazier, K S F / Fox, B D / Fu, J / Gagliardi, C A / Gaillard, L / Gans, J / Ganti, M S / Geurts, F / Ghazikhanian, V / Ghosh, P / Gonzalez, J E / Gorbunov, Y G / Gos, H / Grachov, O / Grebenyuk, O / Grosnick, D / Guertin, S M / Guo, Y / Gupta, A / Gupta, N / Gutierrez, T D / Hallman, T J / Hamed, A / Harris, J W / Heinz, M / Henry, T W / Hepplemann, S / Hippolyte, B / Hirsch, A / Hjort, E / Hoffmann, G W / Horner, M J / Huang, H Z / Huang, S L / Hughes, E W / Humanic, T J / Igo, G / Ishihara, A / Jacobs, P / Jacobs, W W / Jiang, H / Jones, P G / Judd, E G / Kabana, S / Kang, K / Kaplan, M / Keane, D / Kechechyan, A / Khodyrev, V Yu / Kim, B C / Kiryluk, J / Kisiel, A / Kislov, E M / Klein, S R / Koetke, D D / Kollegger, T / Kopytine, M / Kotchenda, L / Kowalik, K L / Kramer, M / Kravtsov, P / Kravtsov, V I / Krueger, K / Kuhn, C / Kulikov, A I / Kumar, A / Kutuev, R Kh / Kuznetsov, A A / Lamb, R / Lamont, M A C / Landgraf, J M / Lange, S / Laue, F / Lauret, J / Lebedev, A / Lednicky, R / Lee, C-H / Lehocka, S / Levine, M J / Li, C / Li, Q / Li, Y / Lin, G / Lindenbaum, S J / Lisa, M A / Liu, F / Liu, H / Liu, J / Liu, L / Liu, Q J / Liu, Z / Ljubicic, T / Llope, W J / Long, H / Longacre, R S / Lopez-Noriega, M / Love, W A / Lu, Y / Ludlam, T / Lynn, D / Ma, G L / Ma, J G / Ma, Y G / Magestro, D / Mahajan, S / Mahapatra, D P / Majka, R / Mangotra, L K / Manweiler, R / Margetis, S / Markert, C / Martin, L / Marx, J N / Matis, H S / Matulenko, Yu A / McClain, C J / McShane, T S / Melnick, Yu / Meschanin, A / Miller, M L / Minaev, N G / Mironov, C / Mischke, A / Mishra, D K / Mitchell, J / Mioduszewski, S / Mohanty, B / Molnar, L / Moore, C F / Morozov, D A / Munhoz, M G / Nandi, B K / Nayak, S K / Nayak, T K / Nelson, J M / Netrakanti, P K / Nikitin, V A / Nogach, L V / Nurushev, S B / Odyniec, G / Ogawa, A / Okorokov, V / Oldenburg, M / Olson, D / Pal, S K / Panebratsev, Y / Panitkin, S Y / Pavlinov, A I / Pawlak, T / Peitzmann, T / Perevoztchikov, V / Perkins, C / Peryt, W / Petrov, V A / Phatak, S C / Picha, R / Planinic, M / Pluta, J / Porile, N / Porter, J / Poskanzer, A M / Potekhin, M / Potrebenikova, E / Potukuchi, B V K S / Prindle, D / Pruneau, C / Putschke, J / Rakness, G / Raniwala, R / Raniwala, S / Ravel, O / Ray, R L / Razin, S V / Reichhold, D / Reid, J G / Reinnarth, J / Renault, G / Retiere, F / Ridiger, A / Ritter, H G / Roberts, J B / Rogachevskiy, O V / Romero, J L / Rose, A / Roy, C / Ruan, L / Russcher, M J / Sahoo, R / Sakrejda, I / Salur, S / Sandweiss, J / Sarsour, M / Savin, I / Sazhin, P S / Schambach, J / Scharenberg, R P / Schmitz, N / Schweda, K / Seger, J / Selyuzhenkov, I / Seyboth, P / Shabetai, A / Shahaliev, E / Shao, M / Shao, W / Sharma, M / Shen, W Q / Shestermanov, K E / Shimanskiy, S S / Sichtermann, E / Simon, F / Singaraju, R N / Smirnov, N / Snellings, R / Sood, G / Sorensen, P / Sowinski, J / Speltz, J / Spinka, H M / Srivastava, B / Stadnik, A / Stanislaus, T D S / Stock, R / Stolpovsky, A / Strikhanov, M / Stringfellow, B / Suaide, A A P / Sugarbaker, E / Sumbera, M / Surrow, B / Swanger, M / Symons, T J M / de Toledo, A Szanto / Tai, A / Takahashi, J / Tang, A H / Tarnowsky, T / Thein, D / Thomas, J H / Timmins, A R / Timoshenko, S / Tokarev, M / Trainor, T A / Trentalange, S / Tribble, R E / Tsai, O D / Ulery, J / Ullrich, T / Underwood, D G / Buren, G Van / van der Kolk, N / van Leeuwen, M / Molen, A M Vander / Varma, R / Vasilevski, I M / Vasiliev, A N / Vernet, R / Vigdor, S E / Viyogi, Y P / Vokal, S / Voloshin, S A / Waggoner, W T / Wang, F / Wang, G / Wang, X L / Wang, Y / Wang, Z M / Ward, H / Watson, J W / Webb, J C / Westfall, G D / Wetzler, A / Whitten, C / Wieman, H / Wissink, S W / Witt, R / Wood, J / Wu, J / Xu, N / Xu, Q H / Xu, Z / Xu, Z Z / Yepes, P / Yoo, I-K / Yurevich, V I / Zborovsky, I / Zhang, H / Zhang, W M / Zhang, Y / Zhang, Z P / Zhong, C / Zoulkarneev, R / Zoulkarneeva, Y / Zubarev, A N / Zuo, J X

Physical review letters

2006 Volume 97, Issue 15, Page(s) 152302

Abstract: Measurements of the production of forward pi0 mesons from p + p and d + Au collisions at square ... in p + p that is suppressed in d + Au at low pion energy. These observations are qualitatively ... root sNN=200 GeV are reported. The p + p yield generally agrees with next-to-leading order perturbative ...

Abstract	Measurements of the production of forward pi0 mesons from p + p and d + Au collisions at square root sNN=200 GeV are reported. The p + p yield generally agrees with next-to-leading order perturbative QCD calculations. The d + Au yield per binary collision is suppressed as eta increases, decreasing to approximately 30% of the p + p yield at eta =4.00, well below shadowing expectations. Exploratory measurements of azimuthal correlations of the forward pi0 with charged hadrons at eta approximately 0 show a recoil peak in p + p that is suppressed in d + Au at low pion energy. These observations are qualitatively consistent with a saturation picture of the low-x gluon structure of heavy nuclei.
Language	English
Publishing date	2006-10-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.97.152302
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Article: An Aberrant Case of Pheochromocytoma in a Young Adult Presenting With Secondary Hypertension: A Case Report With Review of the Literature.

Trimukhe, Deepali / Dhok, Avinash / Phatak, Suresh / Onkar, Prashant

Cureus

2023 Volume 15, Issue 9, Page(s) e44891

Abstract: Pheochromocytoma (PCC) is a rare neuroendocrine catecholamine-secreting tumour of the adrenal gland. It originates from the chromaffin cells found within the adrenal medulla or the extra-adrenal paraganglia. We present a case report of a 24-year-old ... ...

Abstract	Pheochromocytoma (PCC) is a rare neuroendocrine catecholamine-secreting tumour of the adrenal gland. It originates from the chromaffin cells found within the adrenal medulla or the extra-adrenal paraganglia. We present a case report of a 24-year-old female who presented with hypertension, headache, palpitations, chest pain and blurry vision. On ultrasound evaluation, a right suprarenal mass was noted, which was further evaluated using contrast-enhanced computed tomography (CT). Based on our imaging findings, the patient was diagnosed with a case of right-sided pheochromocytoma. The patient was operated on, and our diagnosis was confirmed with histopathological examination.
Language	English
Publishing date	2023-09-08
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.44891
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Article ; Online: In vitro

Bakale, Rajubai D / Phatak, Pramod S / Rathod, Sanket S / Choudhari, Prafulla B / Rekha, Estharla Madhu / Sriram, Dharmarajan / Kulkarni, Ravibhushan S / Haval, Kishan P

Journal of biomolecular structure & dynamics

2023 , Page(s) 1–20

Abstract: In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives ( ...

Abstract	In the present study, we have reported the synthesis of novel isoniazid-triazole derivatives (
Language	English
Publishing date	2023-12-11
Publishing country	England
Document type	Journal Article
ZDB-ID	49157-3
ISSN	1538-0254 ; 0739-1102
ISSN (online)	1538-0254
ISSN	0739-1102
DOI	10.1080/07391102.2023.2291826
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Article ; Online: Clinical and demographic comparison of celiac disease diagnosed during adulthood

Jain, Ajay K / Chatterji, Debi / Bhagat, Priyanka / Jain, Deepika / Sircar, Shohini / Phatak, Satish

JGH open : an open access journal of gastroenterology and hepatology

2023 Volume 7, Issue 12, Page(s) 923–927

Abstract: Background and aim: Celiac disease (CeD) is mainly reported from the northern and western parts of India. In central India, it is believed to be a disease of children, with limited data among adults diagnosed for the first time after the age of 18 years. ...

Abstract	Background and aim: Celiac disease (CeD) is mainly reported from the northern and western parts of India. In central India, it is believed to be a disease of children, with limited data among adults diagnosed for the first time after the age of 18 years. Hence, we aimed to describe CeD's clinical and demographic features among adults and children/adolescents in central India. Methods: This is a retrospective analysis of a prospectively maintained database of all patients diagnosed for CeD from 2010 to 2019. The disease in adults was confirmed when symptoms developed for the first time after 18 years and had positive anti-transglutaminase antibodies with villous atrophy on duodenal biopsy. It was compared with pediatric patients with CeD diagnosed during the same time period. Results: Of the 170 patients diagnosed with CeD, 118 were adults and 52 were children or adolescents. The mean age of presentation of adult CeD was 37.3 ± 11.93 years, while in the pediatric and adolescent group it was 9.19 ± 5.4 years. Classical presentation with chronic, painless, small-bowel-type diarrhea was seen in 44.1% of adults compared to 57.7% in the pediatric age group. Among the adult patients, 55.9% presented with nonclassical symptoms, which included abdominal pain (40.7%) and weight loss (36.4%). The common presenting symptom in children other than diarrhea was weight loss (50%) and abdominal pain (34.6%). Conclusion: CeD is common in central India, with an increasing number of patients being diagnosed for the first time after 18 years of age and presenting more often with nonclassical symptoms.
Language	English
Publishing date	2023-11-30
Publishing country	Australia
Document type	Journal Article
ISSN	2397-9070
ISSN (online)	2397-9070
DOI	10.1002/jgh3.13003
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Article ; Online: Fabrication of D-α-tocopheryl polyethylene glycol 1000 succinates and human serum albumin conjugated chitosan nanoparticles of bosutinib for colon targeting application; in vitro-in vivo investigation.

Manthalkar, Laxmi / Bhattacharya, Sankha / Hatware, Ketan / Sreelaya, Putrevu / Shah, Disha / Jain, Arinjay / Phatak, Niraj

International journal of biological macromolecules

2023 Volume 253, Issue Pt 7, Page(s) 127531

Abstract: ... to develop chitosan (CH)-human serum albumin (HAS)-D-α-tocopheryl polyethylene glycol 1000 (TPGS ...

Abstract	For more effective chemotherapy and targeted treatment of colorectal cancer, this study seeks to develop chitosan (CH)-human serum albumin (HAS)-D-α-tocopheryl polyethylene glycol 1000 (TPGS) nanoparticles (BOS-CH-HSA-TPGS-NPs) coated with Bosutinib (BOS). Nuclear magnetic resonance (NMR) indicated that chitosan's structure was modified by carbodiimide coupling with HSA. We used a Box-Behnken design to find the ideal region for particle size, zeta potential, and entrapment efficiency, eventually emerging at a formulation with these values: 187.14 ± 3.2 nm, 76.2 ± 0.96 %, and 21.1 ± 2.3 mV. Differential scanning calorimetry (DSC), Transmission electron microscopy (TEM), X-ray diffraction (XRD), Atomic force microscopy (AFM), Fourier transform infrared spectroscopy (FTIR), High-performance liquid chromatography (HPLC) were all used to characterize the sample in detail. At a phosphate buffer pH of 7.4, in vitro drug release tests showed both Higuchi model release (0.954) and Fickian diffusion (n = 0.5). Compared to free BOS, HCT116 cell lines showed considerably higher cytotoxicity in in vitro cytotoxicity assays. In male albino Wistar rats, the BOS-CH-HSA-TPGS-NPs also showed enhanced pharmacokinetics, targeting efficiency, and biocompatibility. When used to the treatment of colorectal cancer, the BOS-CH-HSA-TPGS NPs show promise as a sustained-release therapy with improved therapeutic effects by addressing the challenges of poor solubility, poor permeability, and toxic side effects.
MeSH term(s)	Rats ; Animals ; Humans ; Male ; Chitosan ; Nanoparticles/chemistry ; Polyethylene Glycols/chemistry ; Vitamin E/chemistry ; Succinates/chemistry ; Colorectal Neoplasms ; Particle Size ; Drug Carriers/chemistry
Chemical Substances	polyethylene glycol 1000 (U076Q6Q621) ; tocophersolan (O03S90U1F2) ; Chitosan (9012-76-4) ; bosutinib (5018V4AEZ0) ; Polyethylene Glycols (3WJQ0SDW1A) ; Vitamin E (1406-18-4) ; Succinates ; Drug Carriers
Language	English
Publishing date	2023-10-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.127531
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Article: Chondrosarcoma of Iliac Bone Imaging Spectrum With Histopathological Correlation: A Case Report.

Bahurupe, Suchita / Phatak, Suresh / Onkar, Prashant / Ambhore, Ashish N / Trimukhe, Deepali

Cureus

2023 Volume 15, Issue 9, Page(s) e45110

Abstract: Chondrosarcoma is a rare form of carcinoma that originates in the cells of cartilage, the flexible tissue that cushions the joints and gives structure to various parts of the body. This malignant tumour primarily affects adults and is most commonly found ...

Abstract	Chondrosarcoma is a rare form of carcinoma that originates in the cells of cartilage, the flexible tissue that cushions the joints and gives structure to various parts of the body. This malignant tumour primarily affects adults and is most commonly found in the bones of the arms, legs, pelvis, and ribs. The severity and prognosis of chondrosarcoma can vary widely depending on factors such as tumour size, location, and grade. We are reporting a case of an 83-year-old male patient who presented with swelling over the left hip joint. A mass was detected on radiograph and ultrasound that was further characterized using contrast-enhanced CT and MRI. Imaging findings suggested chondrosarcoma. The patient was diagnosed on histopathological examination.
Language	English
Publishing date	2023-09-12
Publishing country	United States
Document type	Case Reports
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.45110
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Article ; Online: Vulvovaginal Complaints as the First Manifestation of Crohn's Disease in Children: Case Report.

Brioso, Xiomara B / Banks, Darnna / Christison-Lagay, Emily / Phatak, Uma P / Vash-Margita, Alla

Journal of pediatric and adolescent gynecology

2023 Volume 36, Issue 5, Page(s) 494–496

Abstract: Background: Crohn's disease, a chronic gastrointestinal inflammatory condition, can involve gynecological structures. Rectovaginal or rectovestibular involvement may be the first sign in the pediatric population and may result in delayed diagnosis and ... ...

Abstract	Background: Crohn's disease, a chronic gastrointestinal inflammatory condition, can involve gynecological structures. Rectovaginal or rectovestibular involvement may be the first sign in the pediatric population and may result in delayed diagnosis and treatment. Case: A 9-year-old premenarchal female with chronic constipation and poor growth presented to the pediatric gynecologist for evaluation of persistent vulvovaginal discharge and vulvar irritation. Examination under anesthesia revealed a rectolabial fistula; colonoscopy was diagnostic of Crohn's disease. Immunotherapy resulted in improvement of symptoms and anatomical changes. Summary and conclusion: In cases of persistent vulvar complaints in a child without clear diagnosis, a high index of suspicion for a non-gynecologic diagnosis is necessary. Collaboration between pediatric gynecologists, gastroenterologists, and surgeons can result in prompt diagnosis and treatment of genital Crohn's disease.
MeSH term(s)	Child ; Humans ; Female ; Crohn Disease/complications ; Crohn Disease/diagnosis ; Vulva ; Fistula
Language	English
Publishing date	2023-05-15
Publishing country	United States
Document type	Case Reports
ZDB-ID	1325079-6
ISSN	1873-4332 ; 1083-3188
ISSN (online)	1873-4332
ISSN	1083-3188
DOI	10.1016/j.jpag.2023.05.007
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Article ; Online: CD44 targeted delivery of hyaluronic acid-coated polymeric nanoparticles against colorectal cancer.

Phatak, Niraj / Bhattacharya, Sankha / Shah, Disha / Manthalkar, Laxmi / Sreelaya, Putrevu / Jain, Arinjay

Nanomedicine (London, England)

2023 Volume 18, Issue 23, Page(s) 1613–1634

Abstract: Aim: ...

Abstract	Aim:
MeSH term(s)	Animals ; Male ; Rats ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Colonic Neoplasms/drug therapy ; Drug Carriers ; Hyaluronic Acid ; Lactic Acid ; Nanoparticles ; Polyglycolic Acid ; Polylactic Acid-Polyglycolic Acid Copolymer
Chemical Substances	Antineoplastic Agents ; Drug Carriers ; Hyaluronic Acid (9004-61-9) ; Lactic Acid (33X04XA5AT) ; Polyglycolic Acid (26009-03-0) ; Polylactic Acid-Polyglycolic Acid Copolymer (1SIA8062RS)
Language	English
Publishing date	2023-10-13
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2277839-1
ISSN	1748-6963 ; 1743-5889
ISSN (online)	1748-6963
ISSN	1743-5889
DOI	10.2217/nnm-2023-0145
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Zs.A 6617: Show issues

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Article: d-α-tocopheryl polyethylene glycol 1000 succinate surface scaffold polysarcosine based polymeric nanoparticles of enzalutamide for the treatment of colorectal cancer: In vitro, in vivo characterizations.

Shah, Disha / Bhattacharya, Sankha / Gupta, Girdhari Lal / Hatware, Ketan Vinayakrao / Jain, Arinjay / Manthalkar, Laxmi / Phatak, Niraj / Sreelaya, Putrevu

Heliyon

2024 Volume 10, Issue 3, Page(s) e25172

Abstract: In this study, Enzalutamide (ENZ) loaded Poly Lactic- ...

Abstract	In this study, Enzalutamide (ENZ) loaded Poly Lactic-
Language	English
Publishing date	2024-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e25172
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Article ; Online: Breast cancer detection using enhanced IRI-numerical engine and inverse heat transfer modeling: model description and clinical validation.

Gutierrez, Carlos / Owens, Alyssa / Medeiros, Lori / Dabydeen, Donnette / Sritharan, Nithya / Phatak, Pradyumna / Kandlikar, Satish G

Scientific reports

2024 Volume 14, Issue 1, Page(s) 3316

Abstract: Effective treatment of breast cancer relies heavily on early detection. Routine annual mammography is a widely accepted screening technique that has resulted in significantly improving the survival rate. However, it suffers from low sensitivity resulting ...

Abstract	Effective treatment of breast cancer relies heavily on early detection. Routine annual mammography is a widely accepted screening technique that has resulted in significantly improving the survival rate. However, it suffers from low sensitivity resulting in high false positives from screening. To overcome this problem, adjunctive technologies such as ultrasound are employed on about 10% of women recalled for additional screening following mammography. These adjunctive techniques still result in a significant number of women, about 1.6%, who undergo biopsy while only 0.4% of women screened have cancers. The main reason for missing cancers during mammography screening arises from the masking effect of dense breast tissue. The presence of a tumor results in the alteration of temperature field in the breast, which is not influenced by the tissue density. In the present paper, the IRI-Numerical Engine is presented as an adjunct for detecting cancer from the surface temperature data. It uses a computerized inverse heat transfer approach based on Pennes's bioheat transfer equations. Validation of this enhanced algorithm is conducted on twenty-three biopsy-proven breast cancer patients after obtaining informed consent under IRB protocol. The algorithm correctly predicted the size and location of cancerous tumors in twenty-four breasts, while twenty-two contralateral breasts were also correctly predicted to have no cancer (one woman had bilateral breast cancer). The tumors are seen as highly perfused and metabolically active heat sources that alter the surface temperatures that are used in heat transfer modeling. Furthermore, the results from this study with twenty-four biopsy-proven cancer cases indicate that the detection of breast cancer is not affected by breast density. This study indicates the potential of the IRI-Numerical Engine as an effective adjunct to mammography. A large scale clinical study in a statistically significant sample size is needed before integrating this approach in the current protocol.
MeSH term(s)	Female ; Humans ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Mammography/methods ; Breast Density ; Hot Temperature ; Breast/diagnostic imaging ; Breast/pathology ; Early Detection of Cancer/methods
Language	English
Publishing date	2024-02-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53856-w
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