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  1. Book: Lu Xun xiao shuo xuan

    Lu, Xun / Yang, Xianyi

    (Lu xun xiao shuo xuan ; 鲁迅小说选)

    2006  

    Title variant Parallelt.:Selected stories of Lu Xun
    Author's details Lu Xun zhu. Yang Xianyi, Dai Naidie yi = Selected stories of Lu Xun / Written by Lu Xun, translated by Yang Xianyi, Gladys Yang
    Series title Lu xun xiao shuo xuan
    鲁迅小说选
    Keywords Bilingual books ; Chinese language materials/Bilingual
    Language English ; Chinese
    Size 473 S, port
    Edition Di 1 ban
    Publisher Wai wen chu ban she
    Publishing place Bei jing
    Document type Book
    Note Chinese and English
    ISBN 7119026984 ; 9787119026985
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book: Xiao ke ji bing shi yu yong yao si lu tan xi

    Yang, Shizhe / Zhang, Xianzhe

    xian Qin zhi Jin Yuan shi qi = On the disease history and herbal medicine of xiao ke (diabetes) in the pre-Qin to Jin Yuan period

    2008  

    Title variant On the disease history and herbal medicine of xiao ke (diabetes) in the pre-Qin to Jin Yuan period
    Author's details Yang Shizhe, Zhang Xianzhe zhu
    MeSH term(s) Diabetes Mellitus/history ; Herbal Medicine/history ; Medicine, Chinese Traditional/history ; History, Ancient ; History, Medieval
    Keywords China
    Language Chinese
    Size x, 508 p. :, ill. ;, 26 cm.
    Edition Di 1 ban.
    Publisher Guo li Zhongguo yi yao yan jiu suo
    Publishing place Taibei Shi
    Document type Book
    ISBN 9789860164107 ; 986016410X
    Database Catalogue of the US National Library of Medicine (NLM)

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  3. Article ; Online: Genus

    Li, Yu / Ye, Ting / Zhang, Xiao-Lu / Yang, Hui / Wu, Yan / Huang, Bao-Hua / Zhao, Qi / Gu, Yu-Feng

    Surgical infections

    2024  

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2024-04-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1440120-4
    ISSN 1557-8674 ; 1096-2964
    ISSN (online) 1557-8674
    ISSN 1096-2964
    DOI 10.1089/sur.2023.352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5617: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: An

    Chen, Shao-Ping / Lin, Xiao-Lu / Qiu, Rong-Zhou / Chi, Mei-Xiang / Yang, Guang

    Insects

    2023  Volume 14, Issue 1

    Abstract: ... Plutella ... ...

    Abstract Plutella xylostella
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662247-6
    ISSN 2075-4450
    ISSN 2075-4450
    DOI 10.3390/insects14010072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Post translational modifications of connexin 43 in ventricular arrhythmias after myocardial infarction.

    Yang, Fan / Zhang, Xiao-Lu / Liu, Huan-Huan / Qian, Ling-Ling / Wang, Ru-Xing

    Molecular biology reports

    2024  Volume 51, Issue 1, Page(s) 329

    Abstract: Ventricular arrhythmias are the leading cause of sudden cardiac death in patients after myocardial infarction (MI). Connexin43 (Cx43) is the most important gap junction channel-forming protein in cardiomyocytes. Dysfunction of Cx43 contributes to ... ...

    Abstract Ventricular arrhythmias are the leading cause of sudden cardiac death in patients after myocardial infarction (MI). Connexin43 (Cx43) is the most important gap junction channel-forming protein in cardiomyocytes. Dysfunction of Cx43 contributes to impaired myocardial conduction and the development of ventricular arrhythmias. Following an MI, Cx43 undergoes structural remodeling, including expression abnormalities, and redistribution. These alterations detrimentally affect intercellular communication and electrical conduction within the myocardium, thereby increasing the susceptibility to post-infarction ventricular arrhythmias. Emerging evidence suggests that post-translational modifications play essential roles in Cx43 regulation after MI. Therefore, Cx43-targeted management has the potential to be a promising protective strategy for the prevention and treatment of post infarction ventricular arrhythmias. In this article, we primarily reviewed the regulatory mechanisms of Cx43 mediated post-translational modifications on post-infarction ventricular arrhythmias. Furthermore, Cx43-targeted therapy have also been discussed, providing insights into an innovative treatment strategy for ventricular arrhythmias after MI.
    MeSH term(s) Humans ; Arrhythmias, Cardiac/metabolism ; Connexin 43/genetics ; Connexin 43/metabolism ; Myocardial Infarction/complications ; Myocardial Infarction/metabolism ; Myocardium/metabolism ; Protein Processing, Post-Translational
    Chemical Substances Connexin 43 ; GJA1 protein, human
    Language English
    Publishing date 2024-02-23
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-024-09290-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1140: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: [Repeated incomplete decompression of nucleus pulposus leads to paralysis:a case report].

    Chen, Sheng-Xing / Yang, Bin-Bin / Qian, Jun-Hai / Lu, Xiao-Xiao

    Zhongguo gu shang = China journal of orthopaedics and traumatology

    2024  Volume 37, Issue 3, Page(s) 316–318

    MeSH term(s) Humans ; Nucleus Pulposus/surgery ; Intervertebral Disc Displacement/surgery ; Decompression, Surgical ; Paralysis ; Lumbar Vertebrae/surgery ; Spinal Fusion ; Retrospective Studies ; Treatment Outcome
    Language Chinese
    Publishing date 2024-03-22
    Publishing country China
    Document type Case Reports ; Journal Article
    ISSN 1003-0034
    ISSN 1003-0034
    DOI 10.12200/j.issn.1003-0034.20220523
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Analysis of clinical characteristics of infections caused by shewanella species.

    Li, Yu / Qi, Rong / Yang, Hui / Zhang, Xiao-Lu / Wu, Yan / Huang, Bao-Hua / Zhao, Qi / Gu, Yu-Feng

    Indian journal of medical microbiology

    2024  Volume 49, Page(s) 100574

    Abstract: Purpose: The Shewanella genus is a rare pathogen of marine origin. In recent years, there has been a continuous increase in infection cases caused by this bacterium, and we have observed the uniqueness of infections caused by this microorganism.: ... ...

    Abstract Purpose: The Shewanella genus is a rare pathogen of marine origin. In recent years, there has been a continuous increase in infection cases caused by this bacterium, and we have observed the uniqueness of infections caused by this microorganism.
    Materials and methods: This study conducted a retrospective analysis of the medical history and laboratory examination data of patients infected with the Shewanella genus over the past decade. Additionally, it employed bioinformatics methods to analyze the relevant virulence factors and antibiotic resistance genes associated with the Shewanella genus.
    Results: Over the past 10 years, we have isolated 51 cases of Shewanella, with 68.82% being Shewanella putrefaciens (35/51 cases) and 31.37% being Shewanella algae (16/51 cases). Infected individuals often had underlying diseases, with 39.22% (20/51) having malignant tumors and 25.49% (13/51) having liver and biliary system diseases primarily characterized by stones. The majority of patients, 62.74% (32/51), exhibited mixed infections, including one case with a combination of infections from three other types of bacteria and five cases with a combination of infections from two other types of bacteria. The identified microorganisms were commonly resistant to ticarcillin-clavulanic acid (23.5%), followed by cefoperazone-sulbactam (19.6%), ciprofloxacin (17.6%), and cefotaxime (17.6%). Bioinformatics analysis indicates that Shewanella can express bile hydrolysis regulators and fatty acid metabolism regulators that aid in adapting to the unique environment of the biliary tract. Additionally, it expresses abundant catalase, superoxide dismutase, and two-component signal transduction system proteins, which may be related to environmental adaptation. Shewanella also expresses various antibiotic resistance genes, including beta-lactamases and aminoglycoside modification enzymes. Iron carriers may be one of its important virulence factors.
    Conclusions: We speculate that the Shewanella genus may exist as a specific colonizer in the human body, and under certain conditions, it may act as a pathogen, leading to biliary infections in the host.
    Language English
    Publishing date 2024-04-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1038798-5
    ISSN 1998-3646 ; 0255-0857
    ISSN (online) 1998-3646
    ISSN 0255-0857
    DOI 10.1016/j.ijmmb.2024.100574
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2639: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Discovery of Novel Metalloenzyme Inhibitors Based on Property Characterization: Strategy and Application for HDAC1 Inhibitors.

    Zhang, Lu / Yang, Yajun / Yang, Ying / Xiao, Zhiyan

    Molecules (Basel, Switzerland)

    2024  Volume 29, Issue 5

    Abstract: Metalloenzymes are ubiquitously present in the human body and are relevant to a variety of diseases. However, the development of metalloenzyme inhibitors is limited by low specificity and poor drug-likeness associated with metal-binding fragments (MBFs). ...

    Abstract Metalloenzymes are ubiquitously present in the human body and are relevant to a variety of diseases. However, the development of metalloenzyme inhibitors is limited by low specificity and poor drug-likeness associated with metal-binding fragments (MBFs). A generalized drug discovery strategy was established, which is characterized by the property characterization of zinc-dependent metalloenzyme inhibitors (ZnMIs). Fifteen potential Zn
    MeSH term(s) Humans ; Histone Deacetylase Inhibitors/pharmacology ; Metalloproteins/chemistry ; Drug Discovery ; Zinc ; Histone Deacetylase 1
    Chemical Substances Histone Deacetylase Inhibitors ; Metalloproteins ; Zinc (J41CSQ7QDS) ; Histone Deacetylase 1 (EC 3.5.1.98) ; HDAC1 protein, human (EC 3.5.1.98)
    Language English
    Publishing date 2024-02-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules29051096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  9. Article: [Identification of Q-markers for Schisandrae Sphenantherae Fructus in treating drug-induced liver injury based on network pharmacology, fingerprint and quantitative analysis].

    Lin, Lu-Jie / Zhang, Ming-Xiao / Li, Hua / Lan, Xue-Mei / Wei, Xiao-Lu / Guo, Cong / Yang, Bin

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2023  Volume 48, Issue 20, Page(s) 5460–5473

    Abstract: This study aims to establish the ultra-performance liquid chromatography(UPLC) fingerprint and multi-indicator quantitative analysis method for Schisandrae Sphenantherae Fructus(SSF) and to screen out the potential quality markers(Q-markers) of ... ...

    Abstract This study aims to establish the ultra-performance liquid chromatography(UPLC) fingerprint and multi-indicator quantitative analysis method for Schisandrae Sphenantherae Fructus(SSF) and to screen out the potential quality markers(Q-markers) of hepatoprotection based on network pharmacology. The similarity analysis was performed using the Chinese Medicine Chromatographic Fingerprint Similarity Evaluation System, which showed that the similarity of the fingerprints of 15 samples from different regions ranged from 0.981 to 0.998. Eighteen common components were identified, from which 3 differential components were selected by cluster analysis and principal component analysis. The "component-target-pathway" network was built to predict the core components related to the hepatoprotective effects. Fourteen core components were screened by network pharmacology. They acted on the targets such as AKT1, CCND1, CYP1A1, CYP3A4, MAPK1, MAPK3, NOS2, NQO1, and PTGS2 to regulate the signaling pathways of lipid metabolism and atherosclerosis, hepatitis B, interleukin-17, and tumor necrosis factor. Considering the chemical measurability, characteristics, and validity, schisantherin A, anwulignan, and schisandrin A were identified as the Q-markers. The content of schisantherin A, anwulignan, and schisandrin A in the test samples were 0.20%-0.57%, 0.13%-0.33%, and 0.42%-0.70%, respectively. Combining the fingerprint, network pharmacology, and content determination, this study predicted that schisantherin A, anwulignan, and schisandrin A were the Q-markers for the hepatoprotective effect of SSF. The results can provide reference for improving the quality evaluation standard and exploring the hepatoprotective mechanism of SSF.
    MeSH term(s) Schisandra/chemistry ; Network Pharmacology ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/chemistry ; Chemical and Drug Induced Liver Injury/drug therapy
    Chemical Substances schizandrin A (74XQL5DO3S) ; schizandrer A (82042-38-4) ; Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2023-12-18
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20230627.201
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3056: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: 新生儿肝衰竭1例.

    Lu, Xiao-Xiao / Lu, Yi / Yang, Lin / Ma, Yang-Yang / Wang, Huan-Huan

    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics

    2024  Volume 26, Issue 2, Page(s) 213–218

    Abstract: The patient was a male infant, born full-term, admitted to the hospital at 28 days of age due to jaundice for 20 days and abdominal distension for 15 days. The patient developed symptoms of jaundice, hepatosplenomegaly, massive ascites, and progressively ...

    Title translation A case of neonatal liver failure.
    Abstract The patient was a male infant, born full-term, admitted to the hospital at 28 days of age due to jaundice for 20 days and abdominal distension for 15 days. The patient developed symptoms of jaundice, hepatosplenomegaly, massive ascites, and progressively worsening liver function leading to liver failure, severe coagulation disorders, and thrombocytopenia one week after birth. Various treatments were administered, including anti-infection therapy, fluid restriction, use of diuretics, use of hepatoprotective and choleretic agents, intermittent paracentesis, blood exchange, and intravenous immunoglobulin, albumin, and plasma transfusions. However, the patient's condition did not improve, and on the 24th day of hospitalization, the family decided to discontinue treatment and provide palliative care. Sequencing of the patient's liver tissue and parental blood samples using whole-exome sequencing did not identify any pathogenic variants that could explain the liver failure. However, postmortem liver tissue pathology suggested congenital hepatic fibrosis (CHF). Given the rarity of CHF causing neonatal liver failure, further studies on the prognosis and pathogenic genes of CHF cases are needed in the future. This article provides a comprehensive description of the differential diagnosis of neonatal liver failure and introduces a multidisciplinary diagnostic and therapeutic approach to neonatal liver failure.
    MeSH term(s) Infant ; Infant, Newborn ; Humans ; Male ; Liver Cirrhosis ; Liver Failure/etiology ; Jaundice ; Genetic Diseases, Inborn
    Language Chinese
    Publishing date 2024-03-04
    Publishing country China
    Document type Case Reports ; English Abstract ; Journal Article
    ISSN 1008-8830
    ISSN 1008-8830
    DOI 10.7499/j.issn.1008-8830.2310117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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