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  1. Article ; Online: Current management of hepatocellular cancer.

    Rampone, Bernardino / Schiavone, Beniamino / Confuorto, Giuseppe

    Current oncology reports

    2010  Volume 12, Issue 3, Page(s) 186–192

    Abstract: Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, being the fifth most frequent cancer worldwide. It usually occurs in the setting of chronic liver disease and has a poor prognosis if untreated. Following the diagnosis, ... ...

    Abstract Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver, being the fifth most frequent cancer worldwide. It usually occurs in the setting of chronic liver disease and has a poor prognosis if untreated. Following the diagnosis, this disease requires multidisciplinary management. Orthotopic liver transplantation is theoretically the best treatment for early, unresectable HCC. However, the major practical obstacle is the extreme shortage of organs, which makes this a practical option only in selected patients. In this report we describe new advancements in diagnosis, classification, and treatment that have emerged in the field of HCC in recent years.
    MeSH term(s) Carcinoma, Hepatocellular/classification ; Carcinoma, Hepatocellular/diagnosis ; Carcinoma, Hepatocellular/therapy ; Chemoembolization, Therapeutic ; Combined Modality Therapy ; Humans ; Liver Neoplasms/classification ; Liver Neoplasms/diagnosis ; Liver Neoplasms/therapy ; Liver Transplantation ; Neoplasm Staging ; Treatment Outcome
    Language English
    Publishing date 2010-03-27
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2057359-5
    ISSN 1534-6269 ; 1523-3790
    ISSN (online) 1534-6269
    ISSN 1523-3790
    DOI 10.1007/s11912-010-0094-3
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  2. Article ; Online: Current role of hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from colorectal cancer.

    Rampone, Bernardino / Schiavone, Beniamino / Martino, Antonio / Confuorto, Giuseppe

    World journal of gastroenterology

    2010  Volume 16, Issue 11, Page(s) 1299–1302

    Abstract: Peritoneal carcinomatosis is one of the most common routes of dissemination of colorectal cancer (CRC). It is encountered in 7% of patients at primary surgery, while it develops in about 4% to 19% of patients after curative surgery and in up to 44% of ... ...

    Abstract Peritoneal carcinomatosis is one of the most common routes of dissemination of colorectal cancer (CRC). It is encountered in 7% of patients at primary surgery, while it develops in about 4% to 19% of patients after curative surgery and in up to 44% of patients with recurrent CRC. Peritoneal involvement from colorectal malignancies has been considered traditionally as a manifestation of terminal disease, due to limited response to conventional surgical and chemotherapeutic treatments. In the past few years the introduction of cytoreductive surgery combined with hyperthermic intraperitoneal chemoperfusion has shown promising results in selected patients. Currently, the surgical management of peritoneal surface malignancies of colonic origin with this combined locoregional therapy has resulted in a significant improvement in survival of these patients. However, further controlled studies will help to standardize indications and the technique of this locoregional therapy in order to achieve an improvement of morbidity and mortality rates.
    MeSH term(s) Carcinoma/secondary ; Carcinoma/therapy ; Chemotherapy, Cancer, Regional Perfusion/methods ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/therapy ; Combined Modality Therapy/methods ; Humans ; Hyperthermia, Induced/methods ; Injections, Intraperitoneal/methods ; Peritoneal Neoplasms/secondary ; Peritoneal Neoplasms/therapy ; Survival Rate
    Language English
    Publishing date 2010-03-18
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v16.i11.1299
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  3. Article ; Online: Current role of hyperthermic intraperitoneal chemotherapy in the treatment of peritoneal carcinomatosis from colorectal cancer

    Bernardino Rampone, Beniamino Schiavone, Antonio Martino, Giuseppe Confuorto

    World Journal of Gastroenterology, Vol 16, Iss 11, Pp 1299-

    2010  Volume 1302

    Abstract: Peritoneal carcinomatosis is one of the most common routes of dissemination of colorectal cancer (CRC). It is encountered in 7% of patients at primary surgery, while it develops in about 4% to 19% of patients after curative surgery and in up to 44% of ... ...

    Abstract Peritoneal carcinomatosis is one of the most common routes of dissemination of colorectal cancer (CRC). It is encountered in 7% of patients at primary surgery, while it develops in about 4% to 19% of patients after curative surgery and in up to 44% of patients with recurrent CRC. Peritoneal involvement from colorectal malignancies has been considered traditionally as a manifestation of terminal disease, due to limited response to conventional surgical and chemotherapeutic treatments. In the past few years the introduction of cytoreductive surgery combined with hyperthermic intraperitoneal chemoperfusion has shown promising results in selected patients. Currently, the surgical management of peritoneal surface malignancies of colonic origin with this combined locoregional therapy has resulted in a significant improvement in survival of these patients. However, further controlled studies will help to standardize indications and the technique of this locoregional therapy in order to achieve an improvement of morbidity and mortality rates.
    Keywords Peritoneal carcinomatosis ; Colorectal cancer ; Intra-abdominal disease ; Recurrence ; Cytoreductive surgery ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Subject code 610 ; 616
    Language English
    Publishing date 2010-03-01T00:00:00Z
    Publisher Baishideng Publishing Group Co. Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Current management strategy of hepatocellular carcinoma

    Bernardino Rampone, Beniamino Schiavone, Antonio Martino, Carmine Viviano, Giuseppe Confuorto

    World Journal of Gastroenterology, Vol 15, Iss 26, Pp 3210-

    2009  Volume 3216

    Abstract: Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons. Surgery, including liver transplantation, is the most important therapeutic approach for patients with this disease. HCC is frequently diagnosed at advanced stages and ... ...

    Abstract Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons. Surgery, including liver transplantation, is the most important therapeutic approach for patients with this disease. HCC is frequently diagnosed at advanced stages and has a poor prognosis with a high mortality rate even when surgical resection has been considered potentially curative. This brief report summarizes the current status of the management of this malignancy and includes a short description of new pharmacological approaches in HCC treatment.
    Keywords Hepatocellular carcinoma ; Locoregional procedures ; Liver transplantation ; Surgical resection ; Systemic treatment ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; Specialties of internal medicine ; RC581-951 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Gastroenterology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2009-07-01T00:00:00Z
    Publisher Baishideng Publishing Group Co. Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Current management strategy of hepatocellular carcinoma.

    Rampone, Bernardino / Schiavone, Beniamino / Martino, Antonio / Viviano, Carmine / Confuorto, Giuseppe

    World journal of gastroenterology

    2009  Volume 15, Issue 26, Page(s) 3210–3216

    Abstract: Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons. Surgery, including liver transplantation, is the most important therapeutic approach for patients with this disease. HCC is frequently diagnosed at advanced stages and ... ...

    Abstract Hepatocellular carcinoma (HCC) still remains a considerable challenge for surgeons. Surgery, including liver transplantation, is the most important therapeutic approach for patients with this disease. HCC is frequently diagnosed at advanced stages and has a poor prognosis with a high mortality rate even when surgical resection has been considered potentially curative. This brief report summarizes the current status of the management of this malignancy and includes a short description of new pharmacological approaches in HCC treatment.
    MeSH term(s) Carcinoma, Hepatocellular/classification ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/pathology ; Carcinoma, Hepatocellular/therapy ; Humans ; Liver Neoplasms/classification ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Liver Neoplasms/therapy ; Liver Transplantation ; Neoplasm Staging ; Prognosis ; Treatment Outcome
    Language English
    Publishing date 2009-07-14
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.15.3210
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  6. Article: Giant appendiceal mucocele: report of a case and brief review.

    Rampone, Bernardino / Roviello, Franco / Marrelli, Daniele / Pinto, Enrico

    World journal of gastroenterology

    2005  Volume 11, Issue 30, Page(s) 4761–4763

    Abstract: Mucocele of the appendix is a rare lesion, characterized by distension of the lumen due to accumulation of mucoid substance. This disease is often asymptomatic and pre-operative diagnosis is rare. If untreated, one type of mucocele may rupture producing ... ...

    Abstract Mucocele of the appendix is a rare lesion, characterized by distension of the lumen due to accumulation of mucoid substance. This disease is often asymptomatic and pre-operative diagnosis is rare. If untreated, one type of mucocele may rupture producing a potentially fatal entity known as pseudomyxoma peritonei. The type of surgical treatment is related to the dimensions and to histology of the mucocele. Appendectomy is used for simple mucocele or for cystadenoma. Right hemi-colectomy is recommended for cystadenocarcinoma. In this paper, we report a case of a 51-year-old woman with a mobile, painless mass in the right lower quadrant of abdomen caused by a giant appendiceal mucocele. Imaging showed a large, tubular, cystic structure extending below from the inferior wall of the cecum. Surgery revealed a giant retro-cecal appendix measuring 17 cm in length and 4 cm in diameter. The final pathologic diagnosis was mucocele caused by mucinous cystadenoma.
    MeSH term(s) Appendiceal Neoplasms/complications ; Appendix ; Cecal Diseases/diagnosis ; Cecal Diseases/etiology ; Cecal Diseases/surgery ; Cystadenoma, Mucinous/complications ; Female ; Humans ; Middle Aged ; Mucocele/diagnosis ; Mucocele/etiology ; Mucocele/surgery
    Language English
    Publishing date 2005-07-20
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v11.i30.4761
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  7. Article: Updates on abdominal desmoid tumors.

    Rampone, Bernardino / Pedrazzani, Corrado / Marrelli, Daniele / Pinto, Enrico / Roviello, Franco

    World journal of gastroenterology

    2007  Volume 13, Issue 45, Page(s) 5985–5988

    Abstract: Desmoid tumor is a monoclonal, fibroblastic proliferation arising in musculoaponeurotic structures. This connective tissue hyperplasia infiltrates locally, recurs frequently after resection but does not metastasize. Abdominal desmoid occurs sporadically, ...

    Abstract Desmoid tumor is a monoclonal, fibroblastic proliferation arising in musculoaponeurotic structures. This connective tissue hyperplasia infiltrates locally, recurs frequently after resection but does not metastasize. Abdominal desmoid occurs sporadically, in association with some familial syndromes and often represents a clinical dilemma for surgeons. The enigmatic biology and anatomical location of abdominal desmoids make treatment recommendations difficult. This distinct pathological entity is reviewed with a specific focus on aetiology and management.
    MeSH term(s) Fibromatosis, Abdominal/diagnosis ; Fibromatosis, Abdominal/etiology ; Fibromatosis, Abdominal/therapy ; Humans ; Neoplasm Recurrence, Local
    Language English
    Publishing date 2007-10-11
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v13.45.5985
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  8. Article: Giant liposarcoma of the mesentery. Report of a case.

    Cerullo, Guido / Marrelli, Daniele / Rampone, Bernardino / Perrotta, Ester / Caruso, Stefano / Roviello, Franco

    Annali italiani di chirurgia

    2007  Volume 78, Issue 5, Page(s) 443–445

    Abstract: Liposarcomas represent the single most common type of soft tissue sarcoma. Its abdominal localization is rare, occurring in only 5% of cases. A 55 year old male was found to have a case of primary giant liposarcoma of the mesenterium with a maximum ... ...

    Abstract Liposarcomas represent the single most common type of soft tissue sarcoma. Its abdominal localization is rare, occurring in only 5% of cases. A 55 year old male was found to have a case of primary giant liposarcoma of the mesenterium with a maximum diameter of 40 cm and weight of 9 kg. Computed tomography revealed the presence of a large mass presenting a dishomogeneous density with an adipose component, probably of mesenteric origin. A xifopubic laparotomy confirmed the presence of a pedunculated growth originating from the mesentery. The mass was removed and the histopathological report noted a well differentiated sclerosing liposarcoma with the peritoneal liquid positive for malignant cells. Surgery currently represents the only possibly curative therapy for this type of tumour but close long-term follow up and accurate evaluation of the clinicopathologic parameters are needed.
    MeSH term(s) Aged ; Humans ; Liposarcoma/pathology ; Liposarcoma/surgery ; Male ; Mesentery ; Peritoneal Neoplasms/pathology ; Peritoneal Neoplasms/surgery
    Language English
    Publishing date 2007-09
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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  9. Article: Colecistite acuta alitiasica da emobilia in politraumatizzato. Caso clinico.

    Martino, Antonio / Rampone, Bernardino / Maharajan, Gautam / Sacco, Maria Lucia / Martino, Giovanni / La Rocca, Francesco / Sansone, Pasquale

    Annali italiani di chirurgia

    2009  Volume 80, Issue 3, Page(s) 225–229

    Abstract: The Authors report the clinical case of polytraumatized patient who has colic abdominal pain and Murphy sign after 68 days from damaging event. This symptomatology is consequent to Acute Acalculous Cholecystitis (ACC) associated with hemobilia. This work ...

    Title translation Acute acalculous cholecystectoctomy associated with haemobilia in polytraumatized subject. Case report.
    Abstract The Authors report the clinical case of polytraumatized patient who has colic abdominal pain and Murphy sign after 68 days from damaging event. This symptomatology is consequent to Acute Acalculous Cholecystitis (ACC) associated with hemobilia. This work may be different because hemobilia in polytraumatized patient, like causal factor of acute cholecystitis, is an isolated case in literature. The Authors discuss on ACC risk factors, diagnosis and therapy.
    MeSH term(s) Cholecystitis/complications ; Cholecystitis/diagnosis ; Cholecystitis/surgery ; Hemobilia/complications ; Hemobilia/diagnosis ; Hemobilia/surgery ; Humans ; Male ; Multiple Trauma/complications ; Young Adult
    Language Italian
    Publishing date 2009-05
    Publishing country Italy
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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  10. Article: Politrauma complesso: gestione poli-specialistica. Caso clinico.

    Martino, Antonio / Rampone, Bernardino / Maharajan, Gautam / Sacco, Maria Lucia / Martino, Giovanni / La Rocca, Francesco / Sansone, Pasquale

    Annali italiani di chirurgia

    2009  Volume 80, Issue 4, Page(s) 325–330

    Abstract: The Authors report the clinical course of M.L., a 22 years old man. He came to our observation after a road accident, in third care. In the former hospital admissions hemodynamic stabilization, surgical haemostasis of multiple hepatic lacerations with ... ...

    Title translation Polyspecialistic treatment of a polytrauma. Case report.
    Abstract The Authors report the clinical course of M.L., a 22 years old man. He came to our observation after a road accident, in third care. In the former hospital admissions hemodynamic stabilization, surgical haemostasis of multiple hepatic lacerations with hemoperitoneum and right leg amputation were performed. He arrived to our department in a critical condition owing to mild respiratory insufficiency due to many rib fractures with sero-haematic spillage into the pleural cavity, in dialytic treatment for acute renal insufficiency consequent to right renal artery damage, soft tissues necrosis of the amputation stump with sepsis and persistent fever until 40 degrees C. The treatment and care of this patient required a team-work with the collaboration of many specialists, namely surgeons, nephrologists, anaesthetists, interventionist radiologists and hyperbaric oxygen therapy experts. Thanks to such collaboration we achieved an excellent quoad vitam result. The aim of this paper is to confirm and emphasize the central role of a Trauma Team, fed in a Trauma Center and in a Trauma System, in the management of complex traumas.
    MeSH term(s) Accidents, Traffic ; Acute Kidney Injury/etiology ; Acute Kidney Injury/therapy ; Adult ; Amputation ; Amputation Stumps/surgery ; Femoral Fractures/complications ; Femoral Fractures/etiology ; Follow-Up Studies ; Humans ; Hyperbaric Oxygenation ; Injury Severity Score ; Laparotomy ; Leg/surgery ; Liver/injuries ; Male ; Multiple Trauma/diagnosis ; Multiple Trauma/diagnostic imaging ; Multiple Trauma/therapy ; Renal Artery/injuries ; Renal Dialysis ; Rib Fractures/etiology ; Shock, Hemorrhagic/etiology ; Tomography, X-Ray Computed ; Trauma Centers ; Treatment Outcome
    Language Italian
    Publishing date 2009-07
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 418927-9
    ISSN 2239-253X ; 0003-469X
    ISSN (online) 2239-253X
    ISSN 0003-469X
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