LIVIVO - Search results -

Search results

Result 1 - 10 of total 68194

Search options

Article ; Online: The Yun/Prohibitin complex regulates adult

Zhao, Hang / Shi, Lin / Li, Zhengran / Kong, Ruiyan / Ren, Xuejing / Ma, Rui / Jia, Lemei / Ma, Meifang / Lu, Shan / Xu, Ran / Binari, Richard / Wang, Jian-Hua / Dong, Meng-Qiu / Perrimon, Norbert / Li, Zhouhua

Proceedings of the National Academy of Sciences of the United States of America

2022 Volume 119, Issue 6

Abstract: Stem cells constantly divide and differentiate to maintain adult tissue homeostasis, and uncontrolled stem cell proliferation leads to severe diseases such as cancer. How stem cell proliferation is precisely controlled remains poorly understood. Here, ... ...

Abstract	Stem cells constantly divide and differentiate to maintain adult tissue homeostasis, and uncontrolled stem cell proliferation leads to severe diseases such as cancer. How stem cell proliferation is precisely controlled remains poorly understood. Here, from an RNA interference (RNAi) screen in adult
MeSH term(s)	Adult Stem Cells/metabolism ; Animals ; Animals, Genetically Modified ; Cell Differentiation/physiology ; Cell Proliferation/physiology ; Drosophila Proteins/metabolism ; Drosophila melanogaster/metabolism ; E2F1 Transcription Factor/metabolism ; Homeostasis/physiology ; Intestines/metabolism ; Prohibitins/metabolism ; RNA Interference/physiology ; Signal Transduction/physiology
Chemical Substances	Drosophila Proteins ; E2F1 Transcription Factor ; Prohibitins
Language	English
Publishing date	2022-02-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2111711119
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1148: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Phosphorylation of Yun is required for stem cell proliferation and tumorigenesis.

Ren, Xuejing / Zhao, Hang / Shi, Lin / Li, Zhengran / Kong, Ruiyan / Ma, Rui / Jia, Lemei / Lu, Shan / Wang, Jian-Hua / Dong, Meng-Qiu / Wang, Yingchun / Li, Zhouhua

Cell proliferation

2022 Volume 55, Issue 5, Page(s) e13230

Abstract: ... understood. Phosphorylation of Yun is essential for ISC proliferation. Yun is essential for the proliferation ... of normal and transformed intestinal stem cells. Our mass spectrometry and biochemical data suggest that Yun ... among these residues is likely interdependent. Furthermore, phosphorylation of each residue in Yun is important ...

Abstract	Stem cells maintain adult tissue homeostasis under physiological conditions. Uncontrolled stem cell proliferation will lead to tumorigenesis. How stem cell proliferation is precisely controlled is still not fully understood. Phosphorylation of Yun is essential for ISC proliferation. Yun is essential for the proliferation of normal and transformed intestinal stem cells. Our mass spectrometry and biochemical data suggest that Yun can be phosphorylated at multiple residues in vivo. Interestingly, we show that the phosphorylation among these residues is likely interdependent. Furthermore, phosphorylation of each residue in Yun is important for its function in ISC proliferation regulation. Thus, our study unveils the important role of post-translational modification of Yun in stem cell proliferation.
MeSH term(s)	Adult ; Cell Proliferation ; Cell Transformation, Neoplastic ; Drosophila Proteins/metabolism ; Humans ; Intestines ; Phosphorylation
Chemical Substances	Drosophila Proteins
Language	English
Publishing date	2022-04-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1064202-x
ISSN	1365-2184 ; 0008-8730 ; 0960-7722
ISSN (online)	1365-2184
ISSN	0008-8730 ; 0960-7722
DOI	10.1111/cpr.13230
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 532: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: [Yun's modified pelvic floor exercise improves female sexual dysfunction].

Chen, Jie / Zhou, Dan / Shi, Chao-Liang / Jiao, Wei / Huang, Ting / Zhu, Ling-Min / Wang, Yang-Yun / Shi, Guo-Wei

Zhonghua nan ke xue = National journal of andrology

2023 Volume 27, Issue 11, Page(s) 986–990

Abstract: Objective: To study the effect and safety of Yun's modified pelvic floor exercise (PFE ... them into an experimental (n = 40) and a control group (n = 40), the former treated by Yun's modified PFE and the latter ... Conclusions: Yun's modified pelvic floor exercise can improve the symptoms of female sexual dysfunction, more ...

Abstract	Objective: To study the effect and safety of Yun's modified pelvic floor exercise (PFE) in the treatment of female sexual dysfunction (FSD). Methods: We enrolled 80 FSD patients from the Outpatient Department of Shanghai Fifth People's Hospital from August 2018 to January 2021 and randomized them into an experimental (n = 40) and a control group (n = 40), the former treated by Yun's modified PFE and the latter by traditional PFE, both for 8 weeks. After 0, 4 and 8 weeks of treatment, we evaluated the clinical effect by comparing the female sexual function indexes (FSFI), including sexual desire, sexual arousal, vaginal lubrication, orgasm, sexual satisfaction and sexual intercourse pain, the male partners' sexual satisfaction, and the pelvic floor muscle strength between the two groups of patients. Results: Thirty-four of the patients in the experimental group and 36 in the control completed the treatment. There were no statistically significant differences in the baseline data between the two groups (P > 0.05). The FSFIs were significantly improved in both the experimental and control groups after 4 and 8 weeks of treatment compared with the baseline (P < 0.05), even more significantly in the experimental than in the control group at 8 weeks (P < 0.05). The effectiveness rate was remarkably increased from 52.8% at 4 weeks to 72.2% at 8 weeks in the experimental group (P < 0.05) and from 29.4% to 44.1% in the control (P < 0.05), even more significantly in the former than in the latter group (P < 0.05). Statistically significant differences were found in muscle tone and type I muscle strength between the two groups at 8 weeks (P < 0.05) but not at 4 weeks (P > 0.05). Type II muscle strength and partners' satisfaction were markedly higher in the experimental than in the control group at 4 and 8 weeks (P < 0.05). No adverse events were observed in either of the two groups. Conclusions: Yun's modified pelvic floor exercise can improve the symptoms of female sexual dysfunction, more effective than the traditional pelvic floor muscle exercise, and with no serious adverse reactions.
Language	Chinese
Publishing date	2023-07-09
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2267480-9
ISSN	1009-3591
ISSN	1009-3591
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6577: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Letter by Lei Wang and Yun-Tao Zhao Regarding Article, "Young Male With Incessantly Wide Complex Tachycardia: What Is the Substrate of the Arrhythmia?"

Wang, Lei / Zhao, Yun-Tao

Circulation

2018 Volume 138, Issue 2, Page(s) 211

MeSH term(s)	Arrhythmias, Cardiac ; Humans ; Male ; Tachycardia
Language	English
Publishing date	2018-07-09
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80099-5
ISSN	1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
ISSN (online)	1524-4539
ISSN	0009-7322 ; 0069-4193 ; 0065-8499
DOI	10.1161/CIRCULATIONAHA.118.034580
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui IV Zs.60: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Efficacy of Yun-type pelvic floor optimal training therapy and PFMT on middle aged women with mild to moderate overactive bladder: a randomized controlled trial.

Wang, Yangyun / Shi, Chaoliang / Wang, Jiawei / Shi, Guowei

Annals of translational medicine

2022 Volume 10, Issue 14, Page(s) 796

Abstract: ... reconstruction training method [Yun-type pelvic floor optimal training (Yun-type training)] for OAB patients ... to moderate OAB. Patients were randomly assigned to receive Yun-type training (n=83) or PFMT (n=67 ... The intervention group was first given Yun-type training for 6 weeks, then switched to PFMT for 6 weeks after 2 ...

Abstract	Background: The symptoms of overactive bladder (OAB) are highly bothersome to patients. In behavioral therapy, traditional pelvic floor muscle training (PFMT) can be boring and monotonous, which can cause poor compliance. It's important to establish a new safe and effective crotch-pelvic floor functional reconstruction training method [Yun-type pelvic floor optimal training (Yun-type training)] for OAB patients. Methods: This randomized, double-blind, crossover trial recruited a total of 150 women with mild to moderate OAB. Patients were randomly assigned to receive Yun-type training (n=83) or PFMT (n=67). The intervention group was first given Yun-type training for 6 weeks, then switched to PFMT for 6 weeks after 2 weeks of elution. Patients in the control group were first treated with PFMT for 6 weeks, and changed to the use of Yun-type training for 6 weeks after 2 weeks of elution. The primary endpoint was overactive bladder symptom scores (OABSS) after 6 and 14 weeks of Yun-type training and PFMT. Results: Yun-type training could significantly improve OABSS compared with PFMT after 6 and 14 weeks (P<0.001). Yun-type training was associated with an improvement in urine, urgency, urge urinary incontinence (UUI), urogenital distress inventory-6 (UDI-6), patient's perception of bladder condition (PPBC), voiding volume (VV), incontinence impact questionnaire-7 (IIQ-7), female sexual function index (FSFI), sexual desire, arousal, pain, satisfaction, pelvic floor muscle tone, type I muscle strength, type II muscle strength, and sex partner satisfaction as compared with PFMT after 6 and 14 weeks. Moreover, nocturia, maximum flow rate (Q Conclusions: Yun-type training could yield additional benefits on OAB symptoms, sexual function, and sex partner satisfaction as compared with PFMT. The superior sexual function resulting from Yun-type training can be explained by the fact that it can contract deep and superficial muscle layers, resulting in increased vaginal wall pressure and blood flow, which further improves FSFI and sex partner satisfaction. It could lead to a new non-invasive treatment for OAB patients. Trial registration: Chinese Clinical Trial Registry ChiCTR-INR-17012192.
Language	English
Publishing date	2022-07-19
Publishing country	China
Document type	Journal Article
ZDB-ID	2893931-1
ISSN	2305-5847 ; 2305-5839
ISSN (online)	2305-5847
ISSN	2305-5839
DOI	10.21037/atm-22-3357
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Erratum: PING PENG, DAYOU ZHAI, ROBIN J. SMITH, QIANWEI WANG, YUN GUO amp; LIPING ZHU (2021) On some modern Ostracoda (Crustacea) from the Tibetan Plateau in SW China, with descriptions of three new species. Zootaxa/, 4942: 501-542.

Peng, Ping / Zhai, Dayou / Smith, Robin J / Wang, Qianwei / Guo, Yun / Zhu, Liping

Zootaxa

2021 Volume 4964, Issue 3, Page(s) zootaxa.4964.3.11

Language	English
Publishing date	2021-04-23
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.4964.3.11
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Erratum: SHUO QI, ZHI-TONG LYU, JIAN WANG, YUN-MING MO, ZHAO-CHI ZENG, YANG-JIN ZENG, KE-YUAN DAI, YUAN-QIU LI, L. LEE GRISMER amp; YING-YONG WANG (2022) Three new species of the genus Boulenophrys (Anura, Megophryidae) from southern China. Zootaxa, 5072: 401438.

Qi, Shuo / Lyu, Zhi-Tong / Wang, Jian / Mo, Yun-Ming / Zeng, Zhao-Chi / Zeng, Yang-Jin / Dai, Ke-Yuan / Li, Yuan-Qiu / Grismer, L Lee / Wang, Ying-Yong

Zootaxa

2022 Volume 5115, Issue 4, Page(s) 600

Language	English
Publishing date	2022-03-16
Publishing country	New Zealand
Document type	Journal Article
ISSN	1175-5334
ISSN (online)	1175-5334
DOI	10.11646/zootaxa.5115.4.10
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Efficacy of Yun-Type Optimized Pelvic Floor Training Therapy for Middle-Aged Women With Severe Overactive Bladder: A Randomized Clinical Trial.

Shi, Chaoliang / Zhou, Dan / Yu, Wandong / Jiao, Wei / Shi, Guowei / Wang, Yangyun

Frontiers in surgery

2021 Volume 8, Page(s) 670123

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2021-07-14
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2021.670123
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Application of the Deep Neural Network in Retrieving the Atmospheric Temperature and Humidity Profiles from the Microwave Humidity and Temperature Sounder Onboard the Feng-Yun-3 Satellite.

He, Qiurui / Wang, Zhenzhan / Li, Jiaoyang

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 14

Abstract: The shallow neural network (SNN) is a popular algorithm in atmospheric parameters retrieval from microwave remote sensing. However, the deep neural network (DNN) has a stronger nonlinear mapping capability compared to SNN and has great potential for ... ...

Abstract	The shallow neural network (SNN) is a popular algorithm in atmospheric parameters retrieval from microwave remote sensing. However, the deep neural network (DNN) has a stronger nonlinear mapping capability compared to SNN and has great potential for applications in microwave remote sensing. The Microwave Humidity and Temperature Sounder (Beijing, China, MWHTS) onboard the Fengyun-3 (FY-3) satellite has the ability to independently retrieve atmospheric temperature and humidity profiles. A study on the application of DNN in retrieving atmospheric temperature and humidity profiles from MWHTS was carried out. Three retrieval schemes of atmospheric parameters in microwave remote sensing based on DNN were performed in the study of bias correction of MWHTS observation and the retrieval of the atmospheric temperature and humidity profiles using MWHTS observations. The experimental results show that, compared with SNN, DNN can obtain better bias-correction results when applied to MWHTS observation, and can obtain higher retrieval accuracy of temperature and humidity profiles in all three retrieval schemes. Meanwhile, DNN shows higher stability than SNN when applied to the retrieval of temperature and humidity profiles. The comparative study of DNN and SNN applied in different atmospheric parameter retrieval schemes shows that DNN has a more superior performance.
MeSH term(s)	China ; Humidity ; Microwaves ; Neural Networks, Computer ; Temperature
Language	English
Publishing date	2021-07-08
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21144673
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Retrieval of the vertical evolution of the cloud effective radius from the Chinese FY-4 (Feng Yun 4) next-generation geostationary satellites

Y. Chen / G. Chen / C. Cui / A. Zhang / R. Wan / S. Zhou / D. Wang / Y. Fu

Atmospheric Chemistry and Physics, Vol 20, Pp 1131-

2020 Volume 1145

Abstract: ... meteorological satellites (FY-4A, Feng Yun 4), we established a new method for objectively obtaining the vertical ...

Abstract	The vertical evolution of the cloud effective radius ( R e ) reflects the precipitation-forming process. Based on observations from the first Chinese next-generation geostationary meteorological satellites (FY-4A, Feng Yun 4), we established a new method for objectively obtaining the vertical temperature vs. R e profile. First of all, R e was calculated using a bispectral lookup table. Then, cloud clusters were objectively identified using the maximum temperature gradient method. Finally, the R e profile in a certain cloud was then obtained by combining these two sets of data. Compared with the conventional method used to obtain the R e profile from the subjective division of a region, objective cloud-cluster identification establishes a unified standard, increases the credibility of the R e profile, and facilitates the comparison of different R e profiles. To investigate its performance, we selected a heavy precipitation event from the Integrative Monsoon Frontal Rainfall Experiment in summer 2018. The results showed that the method successfully identified and tracked the cloud cluster. The R e profile showed completely different morphologies in different life stages of the cloud cluster, which is important in the characterization of the formation of precipitation and the temporal evolution of microphysical processes.
Keywords	Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	290
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Copernicus Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED