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  1. Article: Bidirectional Effects of Mao Jian Green Tea and Its Flavonoid Glycosides on Gastrointestinal Motility.

    Wu, Lei / Jin, Xiang / Zheng, Canwen / Ma, Fengjing / Zhang, Xue / Gao, Pengfei / Gao, Jianhua / Zhang, Liwei

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 4

    Abstract: Mao Jian Tea (MJT) has been generally consumed as a digestive aid for more than a hundred years ... investigated the effect of Mao Jian Green Tea (MJGT) on gastrointestinal motility. The biphasic effects ...

    Abstract Mao Jian Tea (MJT) has been generally consumed as a digestive aid for more than a hundred years in the Shanxi province of China. However, determination of its efficacy still remains elusive. This study investigated the effect of Mao Jian Green Tea (MJGT) on gastrointestinal motility. The biphasic effects of the hydro extracts of MJGT on gastric emptying and small intestinal propulsion of rats were identified in vivo; namely, the low (MJGT_L) and medium (MJGT_M) concentrations promoted gastrointestinal motility (
    Language English
    Publishing date 2023-02-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12040854
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Jian-Pi-Yi-Shen formula alleviates renal fibrosis by restoring NAD+ biosynthesis

    Gao, Liwen / Huang, Xi / Deng, Ruyu / Wu, Shanshan / Peng, Yu / Xiong, Guoliang / Lu, Jiandong / Liu, Xinhui

    Aging

    2023  Volume 16, Issue 1, Page(s) 106–128

    Abstract: Background: Patients with chronic kidney disease (CKD) lack efficacious treatment. Jian-Pi-Yi-Shen ...

    Abstract Background: Patients with chronic kidney disease (CKD) lack efficacious treatment. Jian-Pi-Yi-Shen formula (JPYSF) has demonstrated significant clinical efficacy in treating CKD for decades. However, its renoprotective mechanism has not been fully elucidated. This study aimed to determine whether JPYSF could delay renal fibrosis progression in CKD by restoring nicotinamide adenine dinucleotide (NAD+) biosynthesis.
    Methods: Adenine-diet feeding was used to model CKD in C57BL/6 mice. JPYSF was orally administered for 4 weeks. Human proximal tubular epithelial cells (HK-2) cells were stimulated with transforming growth factor-β1 (TGF-β1) with or without JPYSF treatment. Renal function of mice was assessed by serum creatinine and blood urea nitrogen levels. Renal histopathological changes were assessed using Periodic acid-Schiff and Masson's trichrome staining. Cell viability was assessed using a cell counting kit-8 assay. NAD+ concentrations were detected by a NAD+/NADH assay kit. Western blotting, immunohistochemistry, and immunofluorescence were employed to examine fibrosis-related proteins and key NAD+ biosynthesis enzymes expression in the CKD kidney and TGF-β1-induced HK-2 cells.
    Results: JPYSF treatment could not only improve renal function and pathological injury but also inhibit renal fibrosis in CKD mice. Additionally, JPYSF reversed fibrotic response in TGF-β1-induced HK-2 cells. Moreover, JPYSF rescued the decreased NAD+ content in CKD mice and TGF-β1-induced HK-2 cells through restoring expression of key enzymes in NAD+ biosynthesis, including quinolinate phosphoribosyltransferase, nicotinamide mononucleotide adenylyltransferase 1, and nicotinamide riboside kinase 1.
    Conclusions: JPYSF alleviated renal fibrosis in CKD mice and reversed fibrotic response in TGF-β1-induced HK-2 cells, which may be related to the restoration of NAD+ biosynthesis.
    MeSH term(s) Animals ; Humans ; Mice ; Fibrosis ; Kidney/pathology ; Mice, Inbred C57BL ; NAD/biosynthesis ; Renal Insufficiency, Chronic/metabolism ; Transforming Growth Factor beta1/metabolism
    Chemical Substances NAD (0U46U6E8UK) ; Transforming Growth Factor beta1
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Journal Article
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Jian-Pi-Yi-Shen formula restores iron metabolism from dysregulation in anemic rats with adenine-induced nephropathy.

    Li, Changhui / Huang, Haipiao / Wang, Rui / Zhang, Chi / Huang, Shiying / Wu, Jinru / Mo, Pingli / Yu, Huimin / Li, Shunmin / Chen, Jianping

    Journal of ethnopharmacology

    2023  Volume 312, Page(s) 116526

    Abstract: Ethnopharmacological relevance: Jian-Pi-Yi-Shen (JPYS) is a herbal decoction being used to relieve ...

    Abstract Ethnopharmacological relevance: Jian-Pi-Yi-Shen (JPYS) is a herbal decoction being used to relieve the symptoms of chronic kidney disease (CKD) and its complications, including anemia, for over twenty years. Nonetheless, it is unclear how JPYS influences renal anemia and iron metabolism.
    Aim of the study: An analysis of network pharmacology, chemical profiling, and in vivo experiments was conducted to identify the impact of JPYS on JAK2-STAT3 pathway and iron utilization in renal anemia and CKD.
    Materials and methods: The chemical properties of JPYS and its exposed ingredients were detected in vivo. And based on the aforesaid chemical compounds, the potential targets and signaling pathways of JPYS for renal anemia treatment were predicted by network pharmacology. Afterward, an adenine-feeding animal model of CKD-related anemia was developed to verify the mechanism by which JPYS modulates iron recycling to treat renal anemia. Renal injury was estimated by serum creatinine (Scr), blood urea nitrogen (BUN), histopathological examinations and fibrosis degree. Western blot, enzyme-linked immunosorbent assay (ELISA), quantitative real-time polymerase chain reaction (qPCR) and immunohistochemistry approaches were utilized to assess the levels of JAK2, STAT3 and iron metabolism-related factors.
    Results: There were 164 active ingredients identified in JPYS, including prototypes and metabolites in vivo were identified in JPYS, and 21 core targets were found through network pharmacology based on topological characteristics. Combined with the core targets and pathway enrichment analysis, the majority of the candidate targets were associated with the JAK2-STAT3 signaling pathways. Experimental results indicated that JPYS treatment significantly decreased the expression of BUN and Scr, restored renal pathological damage, down-regulated fibrosis degree, and improved hematological parameters such as red blood cell, hemoglobin and hematocrit in CKD rats. Furthermore, JPYS significantly restored iron metabolism from dysregulation by increasing the levels of iron and ferritin in the serum, inhibiting the production of hepcidin in liver and serum, and regulating transferrin receptor 1 in bone marrow. Meanwhile, the expression of JAK2 and STAT3 was suppressed by JPYS treatment.
    Conclusions: Based on these results, JPYS reduces hepcidin levels by inhibiting the activation of JAK2-STAT3 signaling, thereby protecting against iron deficiency anemia.
    MeSH term(s) Rats ; Animals ; Hepcidins/metabolism ; Adenine ; Anemia/drug therapy ; Iron ; Renal Insufficiency, Chronic/chemically induced ; Renal Insufficiency, Chronic/drug therapy ; Fibrosis
    Chemical Substances Hepcidins ; Adenine (JAC85A2161) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2023-04-23
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2023.116526
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Characterization of key odorants in Langyatai Baijiu with Jian flavour by sensory-directed analysis.

    Du, Jingyi / Li, Yueming / Xu, Jianchun / Huang, Mingquan / Wang, Juan / Chao, Jinfu / Wu, Jihong / Sun, Huibin / Ding, Haimei / Ye, Hong

    Food chemistry

    2021  Volume 352, Page(s) 129363

    Abstract: ... Baijiu with Jian flavour (LBJF) using sensory omics analysis (SOA). A total of 56 odorants were screened ... This study uncovers the characteristics of Jian flavour Baijiu (JFB) and provides a scientific basis ...

    Abstract A study was carried out to determine systematically the key aroma-active compounds of Langyatai Baijiu with Jian flavour (LBJF) using sensory omics analysis (SOA). A total of 56 odorants were screened out using gas chromatography-olfactometry-mass spectrometry (GC-O-MS)/Osme analysis. Among them, 15 aroma-active components were first identified. After quantitation, 30 odorants had odour activity values (OAVs) > 1.0 in LBJF. Recombinant and omission experiments proved that the esters, alcohols, acids, especially ethyl hexanoate, γ-nonalactone, and dimethyl trisulfide, were critical to the flavour of LBJF. The basic and commercial liquors had obvious differences in the skeleton compositions of esters and acids. This study uncovers the characteristics of Jian flavour Baijiu (JFB) and provides a scientific basis for the quality control of JFB, which is helpful for the development of Chinese Baijiu flavour styles.
    MeSH term(s) Alcoholic Beverages/analysis ; Food Analysis/methods ; Gas Chromatography-Mass Spectrometry ; Humans ; Odorants/analysis ; Olfactometry ; Taste ; Volatile Organic Compounds/analysis
    Chemical Substances Volatile Organic Compounds
    Language English
    Publishing date 2021-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 243123-3
    ISSN 1873-7072 ; 0308-8146
    ISSN (online) 1873-7072
    ISSN 0308-8146
    DOI 10.1016/j.foodchem.2021.129363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: [Analysis of classical prescription Jinshui Liujun Jian based on ancient literature].

    Dong, Zi-Liang / Li, Hong-Liang / Luo, Wei-Zao / Qin, Yao / Yu, Qi-Nan / Peng, Shi-Lu / Wang, Xin / Wu, Rui-Jun / Liu, Shi-Qi / Peng, Tao / Huang, Jing / Qing, Yu-Ling / Qin, Shao-Rong / Xu, Rui-Chao

    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

    2021  Volume 45, Issue 23, Page(s) 5639–5644

    Abstract: ... literature containing Jinshui Liujun Jian, including its origin and development. Bibliometric analysis was ... used and information of Jinshui Liujun Jian in ancient Chinese medical literature was then collected ... items of data were obtained from 48 ancient Chinese medicine books. Jinshui Liujun Jian was first ...

    Abstract To provide the ancient literary evidence support for the clinical application and development of classical prescription based on systematical collection and analysis of the ancient Chinese medical literature containing Jinshui Liujun Jian, including its origin and development. Bibliometric analysis was used and information of Jinshui Liujun Jian in ancient Chinese medical literature was then collected for statistical analysis of formula compositions, main indications, dosage, preparation methods, etc. A total of 151 valid items of data were obtained from 48 ancient Chinese medicine books. Jinshui Liujun Jian was first recorded in Jingyue Quanshu written by ZHANG Jiebin. This prescription consisted of Rehmanniae Radix Praeparata, Angelicae Sinensis Radix, Pinelliae Rhizome, Citri Reticulatae Pericarpium, Poria and Glycyrrhizae Radix et Rhizome Praeparata cum Melle, and it was mainly used to treat the deficiency of lung and kidney, edema and excess production of phlegm, or Yin deficiency in the old, insufficient blood-qi, wind-cold evil, cough and disgusting, asthma and excessive phlegm. Doctors in later dynasties mostly followed the prescription compositions, dosages and indications in Jingyue Quanshu, and extended the clinical application of this prescription.
    MeSH term(s) Drugs, Chinese Herbal ; Medicine, Chinese Traditional ; Prescriptions ; Rhizome
    Chemical Substances Drugs, Chinese Herbal
    Language Chinese
    Publishing date 2021-01-26
    Publishing country China
    Document type Journal Article
    ZDB-ID 1004649-5
    ISSN 1001-5302 ; 0254-0029
    ISSN 1001-5302 ; 0254-0029
    DOI 10.19540/j.cnki.cjcmm.20200424.306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Modified Jian-pi-yang-zheng decoction inhibits gastric cancer progression via the macrophage immune checkpoint PI3Kγ.

    Yuan, Mengyun / Zou, Xi / Liu, Shenlin / Xu, Xintian / Wang, Hongxing / Zhu, Min / Xie, Xiaodong / Wang, Haidan / Wu, Jian / Sun, Qingmin

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2020  Volume 129, Page(s) 110440

    Abstract: Jian-pi-yang-zheng Decoction (JPYZ) is a traditional Chinese medicine that is used ...

    Abstract Jian-pi-yang-zheng Decoction (JPYZ) is a traditional Chinese medicine that is used for the treatment of advanced gastric cancer, and it shows good efficacy in patients. A previous study indicated that JPYZ inhibited the progression of gastric cancer via the regulation of tumor-associated macrophages (TAMs), but the underlying molecular target of JPYZ regulation of TAMs has not been determined. The present study used modified-JPYZ (mJPYZ) to extend our investigation of gastric cancer. Our results showed that mJPYZ inhibited gastric cancer progression in vivo and in vitro. We found that mJPYZ decreased the activity of PI3-kinase γ (PI3Kγ) in TAMs, reduced the anti-inflammatory factor IL-10 and increased the expression of pro-inflammatory cytokines, such as TNF-α and IL-1β, which ultimately promoted the conversion of TAMs from M2 to M1. Our findings also indicated that mJPYZ inhibited the growth and metastasis of gastric cancer by alleviating the unfavorable differentiation of TAMs via the PI3Kγ signaling cascades. In conclusion, the present findings indicated that mJPYZ inhibited gastric cancer cell EMT via PI3Kγ-dependent TAM reprogramming, which eventually suppressed gastric cancer growth and metastasis. Our study provides an underlying mechanism of a Chinese medicine in the treatment of gastric cancer via PI3Kγ in macrophages.
    MeSH term(s) Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Cell Differentiation/drug effects ; Cell Movement/drug effects ; Class Ib Phosphatidylinositol 3-Kinase/metabolism ; Coculture Techniques ; Cytokines/metabolism ; Disease Progression ; Drugs, Chinese Herbal/pharmacology ; Epithelial-Mesenchymal Transition/drug effects ; Humans ; Inflammation Mediators/metabolism ; Mice ; Neoplasm Metastasis ; Phenotype ; Protein Kinase Inhibitors/pharmacology ; Signal Transduction/drug effects ; Stomach Neoplasms/drug therapy ; Stomach Neoplasms/enzymology ; Stomach Neoplasms/immunology ; Stomach Neoplasms/pathology ; THP-1 Cells ; Tumor Microenvironment ; Tumor-Associated Macrophages/drug effects ; Tumor-Associated Macrophages/enzymology ; Tumor-Associated Macrophages/immunology ; Tumor-Associated Macrophages/pathology
    Chemical Substances Antineoplastic Agents, Phytogenic ; Cytokines ; Drugs, Chinese Herbal ; Inflammation Mediators ; Protein Kinase Inhibitors ; Class Ib Phosphatidylinositol 3-Kinase (EC 2.7.1.137) ; PIK3CG protein, human (EC 2.7.1.137)
    Language English
    Publishing date 2020-06-29
    Publishing country France
    Document type Journal Article
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2020.110440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Ethanol Extract of Mao Jian Green Tea Attenuates Gastrointestinal Symptoms in a Rat Model of Irritable Bowel Syndrome with Constipation via the 5-hydroxytryptamine Signaling Pathway.

    Wu, Lei / Gao, Liming / Jin, Xiang / Chen, Zhikang / Qiao, Xutong / Cui, Xiting / Gao, Jianhua / Zhang, Liwei

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 5

    Abstract: In a previous study, we demonstrated that the hydro extract of Mao Jian Green Tea (MJGT) promotes ...

    Abstract In a previous study, we demonstrated that the hydro extract of Mao Jian Green Tea (MJGT) promotes gastrointestinal motility. In this study, the effect of MJGT ethanol extract (MJGT_EE) in treating irritable bowel syndrome with constipation (IBS-C) in a rat model constructed via maternal separation combined with an ice water stimulation was investigated. First, a successful model construction was confirmed through the determination of the fecal water content (FWC) and the smallest colorectal distension (CRD) volume. Then, the overall regulatory effects of MJGT_EE on the gastrointestinal tract were preliminarily evaluated through gastric emptying and small intestinal propulsion tests. Our findings indicated that MJGT_EE significantly increased FWC (
    Language English
    Publishing date 2023-03-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12051101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Transcriptome sequencing and network pharmacology-based approach to reveal the effect and mechanism of Ji Chuan Jian against Parkinson's disease.

    Wu, Yao / Bai, Yu / Lu, Yan / Zhang, Zhennian / Zhao, Yang / Huang, Sirui / Tang, Lili / Liang, Yan / Hu, Yue / Xu, Chengcheng

    BMC complementary medicine and therapies

    2023  Volume 23, Issue 1, Page(s) 182

    Abstract: Background: Ji Chuan Jian (JCJ), a classic Traditional Chinese Medicine (TCM) formula, has been ...

    Abstract Background: Ji Chuan Jian (JCJ), a classic Traditional Chinese Medicine (TCM) formula, has been widely applied in treating Parkinson's disease (PD) in China, However, the interaction of bioactive compounds from JCJ with the targets involved in PD remains elusive.
    Methods: Based on the transcriptome sequencing and network pharmacology approaches, the chemical compounds of JCJ and gene targets for treating PD were identified. Then, the Protein-protein interaction (PPI) and "Compound-Disease-Target" (C-D-T) network were constructed by using of Cytoscape. Gene Ontology (GO) enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis were applied to these target proteins. Finally, AutoDock Vina was used for applying molecular docking.
    Results: In the present study, a total number of 2669 differentially expressed genes (DEGs) were identified between PD and healthy controls using whole transcriptome RNA sequencing. Then, 260 targets of 38 bioactive compounds in JCJ were identified. Of these targets, 47 were considered PD-related targets. Based on the PPI degree, the top 10 targets were identified. In C-D-T network analysis, the most important anti-PD bioactive compounds in JCJ were determined. Molecular docking revealed that potential PD-related targets, matrix metalloproteinases-9 (MMP9) were more stably bound with naringenin, quercetin, baicalein, kaempferol and wogonin.
    Conclusion: Our study preliminarily investigated the bioactive compounds, key targets, and potential molecular mechanism of JCJ against PD. It also provided a promising approach for identifying the bioactive compounds in TCM as well as a scientific basis for further elucidating the mechanism of TCM formulae in treating diseases.
    MeSH term(s) Humans ; Molecular Docking Simulation ; Network Pharmacology ; Parkinson Disease/drug therapy ; Parkinson Disease/genetics ; Transcriptome ; China
    Language English
    Publishing date 2023-06-03
    Publishing country England
    Document type Journal Article
    ISSN 2662-7671
    ISSN (online) 2662-7671
    DOI 10.1186/s12906-023-03999-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The Extract of Astragalus membranaceus Inhibits Lipid Oxidation in Fish Feed and Enhances Growth Performance and Antioxidant Capacity in Jian Carp ( Cyprinus carpio var. Jian)

    Jing Xu / Gangfu Chen / Min Wu / Qihui Yang / Huatao Li

    Fishes, Vol 8, Iss 12, p

    2023  Volume 594

    Abstract: ... with their phenolic content. Then, juvenile Jian carp ( Cyprinus carpio var. Jian, 10.2 ± 0.3 g) were fed with diets ...

    Abstract In this study, a linoleic and linolenic acid were incubated with petroleum ether extract, ethyl acetate extract, acetone extract (AE) and aqueous extract of Astragalus membranaceus . The phenolic content and total antioxidant capacity (T-AOC) were determined in the extracts of Astragalus membranaceus (EAms) above. Results showed that EAms decreased the levels of malonaldehyde, conjugated diene, and peroxide value levels in material above. Of all of EAms, AE showed the strongest T-AOC and inhibitory effect on the lipid oxidation. Next, fish feeds were incubated with graded levels of AE. The results showed that AE inhibited lipid oxidation in fish feed. The appropriate dosage for reducing lipid oxidation was 6.74 g AE kg −1 feeds. The effect of EAms on the lipid oxidation may be closely associated with their phenolic content. Then, juvenile Jian carp ( Cyprinus carpio var. Jian, 10.2 ± 0.3 g) were fed with diets containing graded levels of AE (0.0, 1.0, 2.0, 3.0, 4.0, 5.0, 6.0, and 7.0 g kg −1 ) for 60 days. Current data displayed that dietary AE increased the growth performance of fish. The optimum dosage for growth promotion was 5.15 g AE kg −1 diet. This result of AE may be ascribed to its enhancing effect on the activity of digestive and absorptive enzymes and antioxidant capacity in digestive organs of fish. Our present study indicated that EAm holds promise as a natural antioxidant for fish and their feed.
    Keywords Astragalus membranaceus ; lipid oxidation ; growth performance ; digestion ; absorption ; antioxidant ; Biology (General) ; QH301-705.5 ; Genetics ; QH426-470
    Subject code 333
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Bidirectional Effects of Mao Jian Green Tea and Its Flavonoid Glycosides on Gastrointestinal Motility

    Wu, Lei / Jin, Xiang / Zheng, Canwen / Ma, Fengjing / Zhang, Xue / Gao, Pengfei / Gao, Jianhua / Zhang, Liwei

    Foods. 2023 Feb. 16, v. 12, no. 4

    2023  

    Abstract: Mao Jian Tea (MJT) has been generally consumed as a digestive aid for more than a hundred years ... investigated the effect of Mao Jian Green Tea (MJGT) on gastrointestinal motility. The biphasic effects ...

    Abstract Mao Jian Tea (MJT) has been generally consumed as a digestive aid for more than a hundred years in the Shanxi province of China. However, determination of its efficacy still remains elusive. This study investigated the effect of Mao Jian Green Tea (MJGT) on gastrointestinal motility. The biphasic effects of the hydro extracts of MJGT on gastric emptying and small intestinal propulsion of rats were identified in vivo; namely, the low (MJGT_L) and medium (MJGT_M) concentrations promoted gastrointestinal motility (p < 0.05), whereas the high concentration (MJGT_H) showed the opposite effect (p < 0.01). The expression levels of the gastric hormones, GAS, MTL and VIP (p < 0.05) were consistent with the gastrointestinal motility variation, with the exception of MTL in MJGT_H group (p > 0.01). Two flavonoids, eriodictyol (0.152 mg/mL) and luteolin (0.034 mg/mL), and the corresponding glycosides eriodictyol-7-O-glucoside (0.637 mg/mL) and luteolin-7-O-glucoside (0.216 mg/mL), dominated the hydro extracts identified by HPLC and UPLC-ESI-MS. These compounds can regulate the muscle strip contractions isolated from the gastrointestinal tissues. Additionally, the different concentrations also influenced the gut microbiota accordingly characterized by 16S rDNA gene sequencing. The MJGT_L boosted several probiotic bacteria, such as Muribaculaceae (1.77-fold), Prevotellaceae (1.85-fold) and Lactobacillaceae (2.47-fold), and suppressed the pathogenic species such as Staphylococcaceae (0.03-fold) that, conversely, was enriched in the MJGT_H group (1.92-fold). Therefore, the biphasic effect indicated that the dosage of the herbal tea should not be overlooked.
    Keywords Lactobacillaceae ; Staphylococcaceae ; gastrointestinal motility ; genes ; glycosides ; green tea ; herbal tea ; intestinal microorganisms ; intestines ; luteolin ; muscles ; probiotics ; China
    Language English
    Dates of publication 2023-0216
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12040854
    Database NAL-Catalogue (AGRICOLA)

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