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  1. Article ; Online: In Reply to "'Atypical' Anti-GBM Disease: Just Atypical, or Not Anti-GBM Disease at All?"

    Chauveau, Bertrand / Gibier, Jean-Baptiste / Rabant, Marion

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2024  

    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Letter
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2024.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Anatomopathologie et biologie médicale : quelle place dans la formation des étudiants en médecine ?

    Tazi, Asmaa / Rabant, Marion / Lemogne, Cédric / Flamant, Martin / Cariou, Alain / Baron, Stéphanie / Prot-Bertoye, Caroline

    Annales de biologie clinique

    2024  Volume 81, Issue 6, Page(s) 628–639

    Abstract: Pathology and biology are essential in the patient care. However, they suffer from a lack of attractiveness to medicine students. In order to gain insight and improve the visibility and attractiveness of these specialties, we designed a survey and ... ...

    Title translation Integrating pathology and biology into medical education: current state and future directions.
    Abstract Pathology and biology are essential in the patient care. However, they suffer from a lack of attractiveness to medicine students. In order to gain insight and improve the visibility and attractiveness of these specialties, we designed a survey and submitted forms to medical students, laboratory medical staff, and clinical staff from the different hospitals and institutes attached to "Université Paris Cité". The responses (363 students (response rate: 9.1%), 109 medical -laboratory staff (25%), 61 clinical staff (10%)) confirmed the poor visibility of these specialties among students as well as the will of the -medical laboratory staff to be more involved in the student's training. The -development of partnerships between laboratories and clinical -departments, which would allow medical students to spend short periods of time in related laboratories during their clinical internship, is a prospect for improving the teaching of these disciplines. The main expected benefits are to "discover a new specialty" and "to better understand the prescription of laboratory tests", which are crucial aspects for understanding the role of laboratory disciplines and their interaction with clinicians to improve patient care.
    MeSH term(s) Humans ; Education, Medical ; Medicine ; Internship and Residency ; Laboratories ; Biology ; Students, Medical
    Language French
    Publishing date 2024-02-23
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 418098-7
    ISSN 1950-6112 ; 0003-3898
    ISSN (online) 1950-6112
    ISSN 0003-3898
    DOI 10.1684/abc.2023.1857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Microvascular Inflammation of the Renal Allograft: A Reappraisal of the Underlying Mechanisms.

    Lebraud, Emilie / Eloudzeri, Maëva / Rabant, Marion / Lamarthée, Baptiste / Anglicheau, Dany

    Frontiers in immunology

    2022  Volume 13, Page(s) 864730

    Abstract: Antibody-mediated rejection (ABMR) is associated with poor transplant outcomes and was identified as a leading cause of graft failure after kidney transplantation. Although the hallmark histological features of ABMR (ABMRh), i.e., microvascular ... ...

    Abstract Antibody-mediated rejection (ABMR) is associated with poor transplant outcomes and was identified as a leading cause of graft failure after kidney transplantation. Although the hallmark histological features of ABMR (ABMRh), i.e., microvascular inflammation (MVI), usually correlate with the presence of anti-human leukocyte antigen donor-specific antibodies (HLA-DSAs), it is increasingly recognized that kidney transplant recipients can develop ABMRh in the absence of HLA-DSAs. In fact, 40-60% of patients with overt MVI have no circulating HLA-DSAs, suggesting that other mechanisms could be involved. In this review, we provide an update on the current understanding of the different pathogenic processes underpinning MVI. These processes include both antibody-independent and antibody-dependent mechanisms of endothelial injury and ensuing MVI. Specific emphasis is placed on non-HLA antibodies, for which we discuss the ontogeny, putative targets, and mechanisms underlying endothelial toxicity in connection with their clinical impact. A better understanding of these emerging mechanisms of allograft injury and all the effector cells involved in these processes may provide important insights that pave the way for innovative diagnostic tools and highly tailored therapeutic strategies.
    MeSH term(s) Allografts ; Antibodies ; Graft Rejection ; Graft Survival ; HLA Antigens ; Humans ; Inflammation ; Kidney Transplantation/adverse effects
    Chemical Substances Antibodies ; HLA Antigens
    Language English
    Publishing date 2022-03-22
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.864730
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Membranous nephropathy in primary antiphospholipid syndrome.

    Stammler, Romain / Rapoport, Camille / Van Huyen, Jean Paul Duong / Zuily, Stéphane / Olivier, Moranne / Daugas, Eric / Esteve, Emmanuel / de Menthon, Mathilde / Perrochia, Helene / Mussini, Charlotte / Sannier, Aurélie / Rabant, Marion / Buob, David / Karras, Alexandre

    Clinical kidney journal

    2024  Volume 17, Issue 2, Page(s) sfae017

    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfae017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A 39 year-old man with acroparesthesia and uncommon renal arterial lesions. What is the diagnosis?

    Creon, Antoine / Ferriere, Elsa / Rabant, Marion / Van Huyen, Jean-Paul Duong / Isnard, Pierre

    Journal of nephrology

    2022  Volume 36, Issue 1, Page(s) 241–243

    MeSH term(s) Male ; Humans ; Adult ; Kidney/diagnostic imaging ; Kidney/pathology ; Fabry Disease/pathology ; alpha-Galactosidase
    Chemical Substances alpha-Galactosidase (EC 3.2.1.22)
    Language English
    Publishing date 2022-02-23
    Publishing country Italy
    Document type Case Reports ; Journal Article
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-022-01277-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Non-myeloma light chain cast nephropathy: a multicenter retrospective study on clinicopathological characteristics.

    Martins, Ana Cristina / Gibier, Jean-Baptiste / Ronsin, Charles / Kandel-Aznar, Christine / Moreau, Anne / Chapal, Marion / Francisco, Diogo / Sakhi, Hamza / Oniszczuk, Julie / Gueguen, Lorraine / Grunenwald, Anne / Devaux, Mathilde / Karras, Alexandre / Royal, Virginie / Rabant, Marion / Gnemmi, Viviane / Olagne, Jérôme / Van Huyen, Jean-Paul Duong / Isnard, Pierre

    Haematologica

    2024  

    Abstract: Not available. ...

    Abstract Not available.
    Language English
    Publishing date 2024-03-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2024.285031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Evolution of the Definition of Rejection in Kidney Transplantation and Its Use as an Endpoint in Clinical Trials.

    Becker, Jan Ulrich / Seron, Daniel / Rabant, Marion / Roufosse, Candice / Naesens, Maarten

    Transplant international : official journal of the European Society for Organ Transplantation

    2022  Volume 35, Page(s) 10141

    Abstract: This article outlines the evolving definition of rejection following kidney transplantation. The viewpoints and evidence presented were included in documentation prepared for a Broad Scientific Advice request to the European Medicines Agency (EMA), ... ...

    Abstract This article outlines the evolving definition of rejection following kidney transplantation. The viewpoints and evidence presented were included in documentation prepared for a Broad Scientific Advice request to the European Medicines Agency (EMA), relating to clinical trial endpoints in kidney transplantation. This request was initiated by the European Society for Organ Transplantation (ESOT) in 2016 and finalized following discussions between the EMA and ESOT in 2020. In ESOT's opinion, the use of "biopsy-proven acute rejection" as an endpoint for clinical trials in kidney transplantation is no longer accurate, although it is still the approved histopathological endpoint. The spectrum of rejection is now divided into the phenotypes of borderline changes, T cell-mediated rejection, and antibody-mediated rejection, with the latter two phenotypes having further subclassifications. Rejection is also described in relation to graft (dys)function, diagnosed because of protocol (surveillance) or indication (for-cause) biopsies. The ongoing use of outdated terminology has become a potential barrier to clinical research in kidney transplantation. This article presents these perspectives and issues, and provides a foundation on which subsequent articles within this Special Issue of Transplant International build.
    MeSH term(s) Antibodies ; Biopsy ; Graft Rejection/etiology ; Humans ; Kidney/pathology ; Kidney Transplantation ; T-Lymphocytes
    Chemical Substances Antibodies
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 639435-8
    ISSN 1432-2277 ; 0934-0874
    ISSN (online) 1432-2277
    ISSN 0934-0874
    DOI 10.3389/ti.2022.10141
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: IgA nephropathy in children with minimal proteinuria: to biopsy or not to biopsy?

    Cambier, Alexandra / Roy, Jean-Philippe / Dossier, Claire / Patey, Natacha / Rabant, Marion / Boyer, Olivia / Delbet, Jean Daniel / Lapeyraque, Anne-Laure / Hogan, Julien

    Pediatric nephrology (Berlin, Germany)

    2023  Volume 39, Issue 3, Page(s) 781–787

    Abstract: Background: Tubulointerstitial lesions and glomerular inflammation severity have been shown to correlate with proteinuria in children with IgA nephropathy (cIgAN). However, there is a lack of data regarding severity of histopathologic findings in cIgAN ... ...

    Abstract Background: Tubulointerstitial lesions and glomerular inflammation severity have been shown to correlate with proteinuria in children with IgA nephropathy (cIgAN). However, there is a lack of data regarding severity of histopathologic findings in cIgAN in patients with minimal to absent proteinuria since kidney biopsy indications are not well defined in these cases.
    Methods: Twenty-eight cIgAN patients with kidney biopsy from 4 different centers in Paris (France) and Montreal (Canada) with a urine protein/creatinine ratio (UPCr) ≤ 0.03 g/mmol and a normal estimated glomerular filtration rate (eGFR > 90 ml/min/1.73 m
    Results: Median age was 11.82 (9.32-13.45) years, and median follow-up was 4 years (2.87-6.53). At time of biopsy, median eGFR was 116 (102.3-139.7) ml/min/1.73 m
    Conclusion: cIgAN with minimal proteinuria at time of biopsy might be linked with acute and chronic glomerular lesions.
    MeSH term(s) Child ; Humans ; Biopsy ; Glomerular Filtration Rate ; Glomerular Mesangium/pathology ; Glomerulonephritis, IGA/complications ; Glomerulonephritis, IGA/diagnosis ; Glomerulonephritis, IGA/pathology ; Kidney/pathology ; Kidney Glomerulus/pathology ; Proteinuria/etiology ; Proteinuria/pathology ; Retrospective Studies ; Adolescent
    Language English
    Publishing date 2023-09-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-023-06121-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Une biopsie endomyocardique de protocole au cours du suivi d’un transplanté cardiaque (n

    Rabant, Marion / Duong Van Huyen, Jean-Paul / Bruneval, Patrick

    Annales de pathologie

    2020  Volume 41, Issue 1, Page(s) 110–112

    Title translation A protocol endomyocardial biopsy during follow-up of a cardiac transplanted patient (No. 2).
    MeSH term(s) Biopsy ; Follow-Up Studies ; Humans ; Myocardium
    Language French
    Publishing date 2020-10-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2020.09.009
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  10. Article: Une biopsie endomyocardique de protocole au cours du suivi d’un transplanté cardiaque (N

    Rabant, Marion / Duong Van Huyen, Jean-Paul / Bruneval, Patrick

    Annales de pathologie

    2020  Volume 41, Issue 1, Page(s) 106–109

    Title translation A protocol endomyocardial biopsy during follow-up of a cardiac transplanted patient.
    MeSH term(s) Biopsy ; Follow-Up Studies ; Humans ; Myocardium
    Language French
    Publishing date 2020-11-23
    Publishing country France
    Document type Journal Article
    ZDB-ID 225720-8
    ISSN 0242-6498
    ISSN 0242-6498
    DOI 10.1016/j.annpat.2020.10.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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